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Lymphoid neoplasm
This document discusses different types of lymphoid neoplasms, or cancers affecting the lymphatic system. It describes non-Hodgkin's lymphomas like chronic lymphocytic leukemia, MALT lymphoma, and follicular lymphoma. It also discusses Hodgkin's lymphoma and its subtypes of lymphocyte rich, nodular sclerosis, mixed cellularity, and lymphocyte depletion. Specific lymphomas mentioned include acute lymphoblastic leukemia, diffuse large B-cell lymphoma, and Burkitt's lymphoma.
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Lymphoid neoplasm
- 1.
- 2. Non Hodgkin’sLymphomaNon Hodgkin’s Lymphoma Hodgkin’s lymphomaHodgkin’s lymphoma
- 3. NHLNHL Low GradeLowGrade 1.1. CLLCLL 2.2. MALT LymphomaMALT Lymphoma 3.3. FollicularFollicular LymphomaLymphoma 4.4. MycosesMycoses Fungoides /Fungoides / Sezary syndromeSezary syndrome High GradeHigh Grade 1.1. ALLALL 2.2. Diffuse Large BDiffuse Large B cell Lymphomacell Lymphoma 3.3. Burkitt’sBurkitt’s LymphomaLymphoma
- 4. HD / HLHD/ HL 1.1. Lymphocyte RichLymphocyte Rich 2.2. Nodular sclerosisNodular sclerosis 3.3. Mixed cellularityMixed cellularity 4.4. Lymphocyte depletionLymphocyte depletion
- 5. ALLALL FAB classificationFABclassification
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- 19.
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- 24. Hairy cell leukemiaHairycell leukemia
- 25.
Editor's Notes
- #8 L1
- #9 L2
- #10 L3
- #12 Note the large cells with large, pale nuclei containing large purple nucleoli at the arrowheads. These are Reed-Sternberg cells that are indicative of Hodgkin lymphoma. Most of the cellular content of foci of Hodgkin lymphoma consists of reactive lymphoid cells. There are four main subtypes of Hodgkin lymphoma with similar molecular characteristics ("classical HL" with Reed-Sternberg cells that immunohistochemically are positive for CD15 and CD30 but negative for CD45): lymphocyte predominance, nodular sclerosis, mixed cellularity, and lymphocyte depletion. Lymphocyte predominance HL has RS cells that are CD20 positive but CD15 and CD30 negative, more like B cells.
- #13 LP positive for CD 20 It is negative for CD 30
- #14 LP - nodular
- #15 Mixed cellularity
- #16 LD
- #17 NS lacunar type of Reed Sternberg cells