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Lumpy Skin Disease
Other names
• LSD
• Go Basant
• Knopvelsiekte
Etiology:
• Three group of virus
• Group I: Orphan virus is generally present on the skin of normal cattle but
does not appear to cause the disease
• Group II: Allerton virus causes a condition of a mild nature and is isolated
from skin nodules, saliva, nasal secretions and semen.
• Group III: Neethling virus causes severe form and is found in blood, mucus,
milk, saliva and semen.
• lumpy skin disease caused by genus Capripoxvirus
Transmission
• Semen, milk, nasal discharge, lacrimation
• Arthropods: act as vector
• Particularly mosquitoes
• Flies
• Ticks
• LSD is not a zoonotic disease
Economical loss :
Signs:
Clinical Signs:
All ages and
types of cattle
are susceptible,
although very
young calves
and lactating
and
malnourished
cattle
Clinical Sign:
lacrimation,
nasal
discharge,
salivation,
and
lameness
Clinical Signs
Multiple
intradermal
nodules
Diameter
from a few
millimetres
to 4–5cm
Clinical Signs
Flies on the
nodule
Clinical signs
Lymph nodes
enlarged.
Odema
develops on
lower
limbs, brisket,
udder, vulva or
scrotum
Brisket Edema
Nodule on mucous membrane
Clinical Signs:
Nodules over
the whole
body
Clinical Signs:
Secondary
infection can
lead to
mastitis,
abortion and
sterility in
bulls.
Clinical Signs:
The enlarged
skin nodules can
later ulcerate
Secondary Infections:
Severe case:
• Clinical pathology
• Intracellular, eosinophilic inclusion bodies in biopsy material.
• Virus isolation
• Fluorescent antibody
• Serum neutralization
• Polymerase chain reaction (PCR) tests
Differential Diagnose
Treatment:
• No specific treatment is available, but prevention of secondary
infection with antibiotics or sulfonamides is recommended
Vaccination:
• LSD vaccine
• Goat & Sheep vaccine
Control:
• Lumpy skin disease spread by movement of infected cattle,
• Possibly by wind-borne vectors
• Control of cattle movement from uninfected to infected areas.
• Fly repellent
• Cypermethrin spray
• Sangwan powder
Lumpy skin disease by Dr. Mushhood Qazi

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Lumpy skin disease by Dr. Mushhood Qazi