Lowe syndrome is a rare genetic disorder caused by mutations in the OCRL1 gene. It primarily affects males and causes eye, kidney, and central nervous system problems. The main symptoms are cataracts, glaucoma, renal Fanconi syndrome resulting in loss of substances in the urine, and neurological issues like developmental delays. While there is no cure, treatment focuses on managing symptoms like replacing lost substances, eye drops or surgery for glaucoma, and tube feeding for nutritional issues. More research is still needed to fully understand the disease mechanisms.