This document provides an overview of drug information services and the modified systematic approach used to answer drug-related questions. It discusses the need for drug information services, skills required, and how to establish a drug information center. The modified systematic approach involves 7 steps: 1) securing requestor demographics, 2) obtaining background information, 3) determining the ultimate question, 4) developing a search strategy, 5) evaluating/analyzing data, 6) formulating a response, and 7) follow-up. Examples are provided to illustrate how this approach is used to appropriately categorize questions and provide accurate, tailored responses.
REVIEWING THE CLINICIANS PRESCRIPTION AND TREATMENT PROGRESSION IS THE FUNDAMENTAL RESPONSIBILITY OF PHARMACIST. THIS PRESENTATION WILL DEAL WITH VARIOUS ASPECTS OF REVIEWING PATIENT DRUGTHERAPY PLAN
Drug Information Services- DIC and Sources.raviapr7
Drug information services
Drug and Poison information Center, Sources of drug information
Computerized services, and the storage and retrieval of information.
REVIEWING THE CLINICIANS PRESCRIPTION AND TREATMENT PROGRESSION IS THE FUNDAMENTAL RESPONSIBILITY OF PHARMACIST. THIS PRESENTATION WILL DEAL WITH VARIOUS ASPECTS OF REVIEWING PATIENT DRUGTHERAPY PLAN
Drug Information Services- DIC and Sources.raviapr7
Drug information services
Drug and Poison information Center, Sources of drug information
Computerized services, and the storage and retrieval of information.
It is defined as knowledge of fact through reading, study or practical experience on chemical substance that is used in diagnosis, prevention and treatment of diseases.
It covers all type of information including; objective and subjective information as well as information gathered by scientific observation or practical experience.
The all the content in this profile is completed by the teachers, students as well as other health care peoples.
thank you, all the respected peoples, for giving the information to complete this presentation.
this information is free to use by anyone.
2. Minimum Standard for Hospital Pharmacy_ASHP_2022-2023.pptxssuserca7d2c
I’m going back in a minute I need a little more help I have a couple things I have a question about for the next two days and then I’m not going back in for a little while I need help I have a little more money to pay my my mom has to go back in the house so I’m going back in to the hospital so I’m going back to my room so I’m going back home to do my homework
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
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Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
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Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
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LITERATURE EVALUATION.pptx
1. HARAMAYA UNIVERSITY HIWAT
FANA COMPREHENSIVE SPECIALIZED
HOSPITAL CLINICAL PHARMACY AND
DRUG AND POISON INFORMATION
SERVICE (DPIS) UNIT
BY SALAHADIN A. (B.PHARM)
1
3. At the end of this lecture the student will
be able to:
• Describe need for drug information service
• Describe skills needed for drug information service
• Describe what is the modified systematic approach
used in answering drug information questions
• List the 7 steps involved in the MSA in answering DI
questions, and discuss the rational of each step
• Use the modified systematic approach in answering
drug information questions
3
5. • Providing medication information is among the
most fundamental responsibilities of pharmacists
The information can be given for;
• patient specific, as an integral part of
pharmaceutical care,
• a group of patients, such as in the development of
a therapeutic guideline, publishing an electronic
newsletter, or updating a website.
5
6. Definition of Terms
Drug information: The process of provision of
unbiased, well-referenced, and critically evaluated
information
Drug informatics: A technologically advanced version
of drug information. This often denotes the electronic
management of drug information.
It emphasizes the use of technology as an integral tool
in effectively organizing, analyzing, and managing
information on medication use in patients.
6
7. • Drug information centre (DIC): A physical location
where pharmacists have the resources (e.g., books,
journals, and computer systems) to provide drug
information service.
• Drug information service (DIS): A professional
service aimed at providing drug information usually
located DIC.
• Drug information Specialists: The individual
responsible for operation of the DIC…….The one
who store, retrieve, select, evaluate, and
disseminate drug information
Definition of Terms ….
7
8. • In 1960s, the availability of new drugs (first
generation cephalosporin) was providing challenges
for practitioners to keep in line and make
appropriate decisions for their patients
• No way to effectively communicate the wealth of
information to those needing it…. drug information
specialist was viewed as a person who could bridge
the gap and effectively communicate drug
information
History
8
9. History…
• In 1962, the first drug information center was
established at the University of Kentucky Medical
Center…..area separated from pharmacy
• It acted as a “major source of selected,
comprehensive drug information for staff physicians
and dentists to allow them to evaluate and compare
drugs”
9
10. • In following years various centers were opened
• The centers were given the role of retrieving,
selection, evaluating, and dissemination
• Information would be disseminated to respond to
specific questions, to assist in the evaluation of drugs
for use in the hospital, or to inform others through
newsletters of current developments related to
drugs.
History…
10
11. In Ethiopia
• HIV/AIDS Twinning Center partners at Addis Ababa
University and Howard University of Washington…..
opened a model Drug Information Center 2009 at
Black Lion Hospital.
History…
11
12. WHY DRUG INFORMATION SERVICE NOW??
• In our modern world, information is everywhere… but the
source and the interpretation may not be reliable
• ……..selecting and organizing the information in
manageable way needs systematic approach
• As a pharmacist we have responsibilities to provide
reliable and accurate drug information…. For health
professionals, patients, careers and the public in general
12
13. WHY DRUG INFORMATION….
• Accessing, reviewing, analyzing, evaluating, and
interpreting the clinical drug literature are important
responsibilities of pharmacist, who are the “drug
experts”.
• To accomplish this, pharmacists need to know how
and where to find clinical drug literature, how to
evaluate it, and how to put it in practice.
13
14. Other deriving factors;
• Change in philosophy of pharmacy practice( from
product to patient focused care)
• Occurrences of adverse drug events
• Growth of information technology
• Changes in the health care environment with a
focus on evidence-based medicine
• The sophistication of medication therapy
• The self-care movement
WHY DRUG INFORMATION….
14
15. Services under DIS
• Support for clinical services/ Information for
practitioners
– Answering drug related questions
– Developing criteria/guidelines for medication use
• Development of medication use policies, formulary
management
• Publications--- newsletter, journal columns, websites
• Education in-services for health professionals, students,
consumers
• Medication use evaluation
• Coordination of reporting programs, e.g., adverse
medication reactions
15
16. DIS is both Reactive and proactive
• Information or advice given in response to questions
or enquiries about medicines is referred to as
‘reactive’ drug information.
• ‘Proactive’ drug information involves the
preparation of newsletter, websites, etc. in an
attempt to educate or raise awareness of key
therapeutic issues.
16
17. WHAT MEDICATION INFORMATION SKILLS DO
WE NEED?
• Assess available information and gather situational
data needed to characterize question or issue
• Formulate appropriate question(s)
• Use a systematic approach to find needed
information
• Evaluate information critically for validity and
applicability
17
18. SKILLS WE NEED…
• Develop, organize, and summarize response for
question or issue
• Communicate clearly when speaking or writing,
considering the audience level
• Anticipate other information needs
18
20. 20
Space
Sufficient for storage of reference
collection and provision of service
Office Equipments
Computer
Photocopier
Telephone
Filing cabinets
Shelving
Desks, chairs
Journal display rack
Internet access
21. Location
– Should be readily accessible to all prospective
users
– Located within;
• The Hospitals
• Medical or Pharmacy association
• Drug regulatory Authority
• Ministry of Health
– Located to have ready access to a good
facilities like internet
21
22. Personnel
• Requires a Registered Pharmacist
– Education and Training
• Formal DI training
• Computer-based information System
• Experience –ward and clinical-based
experience is particularly desirable
22
23. • Competence in evaluation, selection and utilization
of the Professional literature
• Good written and verbal communication skills
• Knowledge of clinical drug use and therapeutics
• Knowledge and acceptance of the legal and ethical
responsibilities
23
Particular Skills Needed
25. • An essential component within drug information
service is the ability to effectively answer
questions posed by health care professionals and
individual patients
• There are various methods for receiving,
researching, and providing answers to drug
information questions. ……However, most DICs and
pharmacists follow a basic pattern.
25
26. • More than providing an answer to a question, they
should provide solutions to therapeutic problems
• Isolated therapeutic answers do not usually provide
adequate solutions
• Responses should follow thoughtful process that
aims at extracting the relevant information and
synthesizing relevant answers
26
27. In 1975, Watanabe et al. presented a systematic
approach for responding to drug information
requests. The systematic approach comprised of five
steps
Step 1: Classification of the request
Step 2: Obtaining background information
Step 3: Systematic search
Step 4: Response
Step 5: Re-classification
27
28. Modified systematic approach
Step 1: Secure demographics of requestor
Step 2: Obtain background information
Step 3: Determine and categorize the ultimate question
Step 4: Develop strategy and conduct search
Step 5: Perform evaluation, analysis and synthesis
Step 6: Formulate and provide response
Step 7: Conduct follow-up and documentation
28
29. Step 1: Secure demographics of requestor
• Gather general demographic information about the
requestor.
• Assessing the sophistication of the requestor allows
information to be provided that best meets an
individual’s needs…. determine the requestor’s
position, training, and anticipated knowledge
• Secure a mechanism for delivery of the response….
telephone number(s), fax number, and/or address
(mail or e-mail) or location
29
30. Example 1:
• If a patient and a physician inquired about how the
new medication Prandin®/Repaglinide works (i.e.,
pharmacology), the depth of the response would
differ for each individual.
Answer 1
• The new medication is the first agent approved in
the meglitinide class and is a nonsulfonylurea
insulin releasing oral hypoglycemic agent for type 2
diabetes mellitus.
Answer 2
• The new medicine acts by improving the way your
body processes sugar. 30
31. Step 2: Obtain background information
• The responder must utilize good communication
skills and ask thoughtful, pertinent questions of the
requestor to characterize fully precise information
need.
• Background information helps to clarify the
question and is a critical step in the process.
• When background questions are utilized
appropriately, the response to information requests
or inquiries is very efficient.
31
32. Obtain background information…
• The requestor’s name
• The requestor’s affiliation (institution or practice) if
a health care professional
• The resources that the requestor already consulted
• Whether the request is patient specific or academic
• The patient’s diagnosis, other medications, and
pertinent medical information
• The urgency of the request (i.e., negotiate the time
response)
32
33. Example 2:
• A pharmacist is asked, "what is the dose of
amoxicillin (Amoxil®)?”
• This question could be answered quickly (and
potentially inaccurately) by stating that the normal
dosage as 500 mg every eight hours.
• The question also could be answered by gathering
background information concerning the origin of
the question.
33
34. • If an information request pertains to a
specific patient, the following patient-
specific background Information might be
required in order to formulate an
appropriate response:
–age, weight, type of infection, concurrent
disease states, other medication
–relevant past medical history including
allergies
–preferred dosage form 34
35. Step 3: Determine and categorize the ultimate
question
• Determining the ultimate question is accomplished easily
once sufficient background information is obtained.
• Often the initial question differs significantly from the
ultimate of final question.
• Once the ultimate question is identified and clear, the
drug information specialist can then quickly categorize
the request into various categories before begin the
search.
35
36. The questions can be categorized under:
• Adverse drug reaction,
• Availability,
• Complementary and Alternative medicine,
• Compounding,
• Dose,
• Drug compatibility/stability,
• Drug interactions,
• Drug identification,
• pediatric dose, etc..
36
37. • The major purpose of this categorization is to
minimize the search timing and increase the
specificity.
• Example: In the previous example above, the
amoxicillin request pertains to a dose. Therefore,
this question would be classified as Dose.
37
38. Step 4: Develop strategy and conduct
search
• The categorization of the request or enquiry prompts
(on time) the resource selection process. For
example, the categorization of a question as “adverse
effect” suggests the use of adverse effect oriented
resources.
• Once resources have been selected, they are
prioritized based on the probability of their
containing the information or data desired.
38
39. Example 3:
• In the previous example above, the amoxicillin
request pertains to a dose.
• The following are examples of references that
provide this information:
– American Hospital Formulary Service (AHFS),
– Facts and Comparisons,
39
40. Step 5: Data evaluation, analysis and
synthesis
• The pharmacist should confirm information with
other references to assure consistency between
various resources.
• The pharmacist should apply his or her techniques
and skills for literature evaluation and clinical
application for statistical analysis
• This step requires strong literature evaluation skills
• Knowledge of Evidence based medicine, study
design, research, and statistical concepts is essential
40
41. Step 6: Formulation and provision of response
• After careful analysis and synthesis of
information, the drug information specialist
formulates a response and then accurately
conveys the response back to the requestor of
information.
• This requires strong verbal and written
communication skills.
41
42. Format for logical argument in response
formulation
Step I. Present the competing viewpoints or considerations
Step II. State the assessment of the literature or
information reviewed and claim the superior viewpoint
Step III. Briefly disprove the major strengths and present
weaknesses of the inferior viewpoint
Step IV. Defend the major weaknesses and promote the
strengths of the superior viewpoint
Step V. Restate the final assessment in support of the
superior viewpoint.
42
43. Step 7: Follow-up & documentation
• Follow-up is the process of verifying the
appropriateness, correctness, and completeness of
a response following the communication.
Certain circumstances command follow-up:
• Patient-specific requests especially if judgmental
(i.e., therapeutic assistance or dosing
recommendations)
• Any situation in which a therapeutic decision was
dependent on assumptions or “soft” data
43
44. • Thorough documentation is essential for reducing
liability and potentially promoting the development
of a continual service.
• The ultimate question (as verified by the requestor),
the materials searched (with pertinent findings
noted), the response, and follow-up should be
documented.
44
45. Assignment
1) A caller requests information regarding the use of aspirin
for the prevention of preeclampsia.
• What specifics regarding caller demographics should be
secured?
• What questions should be asked to obtain background
information from the caller?
• Categorize the question and develop possible search
strategies.
2) Select pertinent drug related issues and prepare news
letter
3) Use given format and systematic approach to fill the drug
query and response
45
46. Reference
• C. R. Kothari, Research Methodology, Methods
and Techniques, 2nd Revised Edition, 2004.
46
Finding the piece of information relevant to a clinical problem can be like finding a needle in a haystack; it is difficult for the practitioner to know which source is best for a specific situation”
The pharmacist can serve as a
resource for issues regarding cost-effective medication selection and use, medication policy
decisions (drug benefits), medication information resource selection, or practice-related issues.
Medication information: recently used term to convey the management and use of information on medication therapy and signify the broader role that all pharmacists take in information provision.
So this course helps to educate on how to efficiently research interpret, collate and disseminate information in the most usable form.
Drug information is the sum of all of the data and knowledge
generated by throughout this life cycle. The diversity and
number of customers for this information is huge, ranging from
the researcher, physician, pharmaceutical benefit manager,
insurer to the consumer. The relevance of the different types
of information will vary with circumstance but little will be
totally irrelevant. For example, a particular pattern of gene
expression seen in early clinical trials may indicate that a
particular patient is susceptible an adverse side effect, such as
liver toxicity.
Currently, in United states 80% of the Hospitals have DIC
In Hiwot Fana, DIC was established in 2011??
Drug information provision is an essential part of pharmacy practice. The provision of medication information is among the most fundamental responsibilities of pharmacists. The information may be either patient specific, as an integral part of pharmaceutical care, or relative to a group of patients, such as in the development of a therapeutic guideline, publishing an electronic newsletter, or updating a website.
In present situation, the drug information opportunities are developing and expanding with changes in the health care environment. Also the pharmacists can serve as a resource for issues regarding cost-effective medication selection and use, medication policy decisions (drug benefits), medication information resource selection, or practice-related issues. Health professionals, patients, carers and the public regularly ask pharmacists for information and advice and it is vital that this should be reliable, accurate and up to date. To carry out these roles effectively, pharmacists need to know how and where to find information, how to evaluate it, and how to put it in practice. In our modern world, information is everywhere. It is presented on television, radio, sent from computer to computer over the internet, and passed from person to person using telephones and fax machines. The great challenge in sorting out the current information from the dated, the reliable from the questionable, the actual from the imagined. Practitioners and scientists must be able to find and identify different types of information in a variety of formats and media. In addition to meeting their own information needs, pharmacists must also be able to assist patients in meeting their information needs with regard to drugs, therapies and diseases. Accessing, reviewing, analyzing, evaluating, and interpreting the clinical drug literature are important responsibilities of health-care practitioners; this is particularly true for pharmacist, who are the “drug experts”.
With national efforts to expand access to care while reducing health care costs, the advent of consumerism, and the integration of new technologies, medication information opportunities are growing in several areas including managed care organizations, pharmaceutical industry, medical and specialty care clinics, scientific writing and medical communication companies, and the insurance industry.
Evidence-based medicine is an approach to practice and teaching that integrates current clinical research evidence with pathophysiologic rationale, professional expertise, and patient preferences to make decisions for a population.
Pharmacists need to be able to evaluate the medication use issues for a group of patients; search, retrieve, and critically evaluate the scientific literature; and apply the information to the targeted group of patients.
The WWW, a method of sharing information over the Internet, allows the user to easily access the scientific literature, government publications, items in the news, and many other things.
BioMed Central (<<www.biomedcentral.com>>) and PubMed (<<www.pubmedcentral.nih.gov>>) are allowing individuals to access millions of articles quickly, easily, and free of charge.
IOM analysts
estimate that prescription medications are responsible for up to 7000 American deaths per
year, with the cost of drug-related morbidity and mortality being nearly U.S. $77 billion per year
Drug information service has different benefit;
For health care in general..
Enable cost-effective medication selection
Helps medication policy decisions
For health care providers…..
For example a Pharmacist (DI) receives a query from a physician/healthcare provider
Options:
1- Answer immediately (from your background knowledge) or
2- Asks questions to get the correct picture….systematic approach
These approaches can be
applied in any area while practicing pharmacy, including community pharmacy, pharmaceutical
industry,
institutional pharmacy
management, as well as general application in any type of
professional
consultation.
These approaches can be
applied in any area while practicing pharmacy, including community pharmacy, pharmaceutical
industry,
institutional pharmacy
management, as well as general application in any type of
professional
consultation. Th
Obtaining background information should be part of a seamless transition from gathering the requestor’s demographic information to a focus on the question itself.
If the
question is patient specific, important information to acquire would include the
patient's age, weight, allergies, type of infection, concurrent disease states, other
medications, and preferred dosage form (e.g., oral suspension, capsules, or
chewable tablets). For example, amoxicillin may not be the best agent to select for
the infection. In addition, the dose of amoxicillin can be 500 mg every eight hours
Without prioritization, resources may be utilized based on ease of access or degree of comfort instead of probable efficiency.