Leprosy, also known as Hansen's disease, is a chronic infectious disease caused by Mycobacterium leprae that mainly affects the skin, nerves, respiratory tract, and eyes. It can occur at any age and is transmitted through droplets from the nose and mouth during prolonged close contact with untreated cases. While not very infectious, it has a long incubation period of 1-20 years and can cause discolored skin patches, thickened nerves, and sensory loss if left untreated.