Each kidney contains over 1 million tiny structures called nephrons. Each nephron has a glomerulus, the site of blood filtration. The glomerulus is a network of capillaries surrounded by a cuplike structure, the glomerular capsule (or Bowman’s capsule). As blood flows through the glomerulus, blood pressure pushes water and solutes from the capillaries into the capsule through a filtration membrane. This glomerular filtration begins the urine formation process.Inside the glomerulus, blood pressure pushes fluid from capillaries into the glomerular capsule through a specialized layer of cells. This layer, the filtration membrane, allows water and small solutes to pass but blocks blood cells and large proteins. Those components remain in the bloodstream. The filtrate (the fluid that has passed through the membrane) flows from the glomerular capsule further into the nephron.The glomerulus filters water and small solutes out of the bloodstream. The resulting filtrate contains waste, but also other substances the body needs: essential ions, glucose, amino acids, and smaller proteins. When the filtrate exits the glomerulus, it flows into a duct in the nephron called the renal tubule. As it moves, the needed substances and some water are reabsorbed through the tube wall into adjacent capillaries. This reabsorption of vital nutrients from the filtrate is the second step in urine creation.The filtrate absorbed in the glomerulus flows through the renal tubule, where nutrients and water are reabsorbed into capillaries. At the same time, waste ions and hydrogen ions pass from the capillaries into the renal tubule. This process is called secretion. The secreted ions combine with the remaining filtrate and become urine. The urine flows out of the nephron tubule into a collecting duct. It passes out of the kidney through the renal pelvis, into the ureter, and down to the bladder.The nephrons of the kidneys process blood and create urine through a process of filtration, reabsorption, and secretion. Urine is about 95% water and 5% waste products. Nitrogenous wastes excreted in urine include urea, creatinine, ammonia, and uric acid. Ions such as sodium, potassium, hydrogen, and calcium are also excreted
Human kidney,structure and functions of kidneyAnand P P
human kidney structural and functions.different types of structural components present in kidney and each structure having definite functions.structural and functional aspects of kidney.
Nephron (The Guyton and Hall physiology)Maryam Fida
Structural and Functional unit of kidney is called nephron.
There are about 1.3 million nephron in each kidney.
New nephrons can not be regenerated by kidneys.
Functioning nephrons decrease about 10 % every 10 years at the age of 40.
At the age of 80, there are 40 % of functioning nephrons as compared to 40 yrs.
It is formed by two parts.
1. GLOMERULUS
2. BOWMAN’S CAPSULE
1- Glomerulus:
It consists of tuft of glomerular capillaries.
There is anastomosing & branching network of glomerular capillaries.
Glomerular capillaries have high hydrostatic pressure (nearly 60 mm Hg) as compared with other capillaries.
Glomerulus is surrounded by a membranous cover called Bowman’s capsule.
Each glomerulus is about 0.2 mm in diameter.
Glomerulus and Bowman’s capsule together constitute renal corpuscle.
Each renal tubule is divided into various part as they have different functions.
i- Proximal convulated tubule.
It is continuation of Bowman’s capsule.
ii- Loop of Henle. It is continuation of prox. conv. tubule.
* Loop of Henle has three parts.
a- descending limb,
b- u turn or bend in medulla and
c- ascending limb.
Ascending limb has initial thin segment followed by thick segment.
At the end of thick ascending limb, there is short segment called macula densa, which plays important role in controlling functions of nephron.
Each kidney contains over 1 million tiny structures called nephrons. Each nephron has a glomerulus, the site of blood filtration. The glomerulus is a network of capillaries surrounded by a cuplike structure, the glomerular capsule (or Bowman’s capsule). As blood flows through the glomerulus, blood pressure pushes water and solutes from the capillaries into the capsule through a filtration membrane. This glomerular filtration begins the urine formation process.Inside the glomerulus, blood pressure pushes fluid from capillaries into the glomerular capsule through a specialized layer of cells. This layer, the filtration membrane, allows water and small solutes to pass but blocks blood cells and large proteins. Those components remain in the bloodstream. The filtrate (the fluid that has passed through the membrane) flows from the glomerular capsule further into the nephron.The glomerulus filters water and small solutes out of the bloodstream. The resulting filtrate contains waste, but also other substances the body needs: essential ions, glucose, amino acids, and smaller proteins. When the filtrate exits the glomerulus, it flows into a duct in the nephron called the renal tubule. As it moves, the needed substances and some water are reabsorbed through the tube wall into adjacent capillaries. This reabsorption of vital nutrients from the filtrate is the second step in urine creation.The filtrate absorbed in the glomerulus flows through the renal tubule, where nutrients and water are reabsorbed into capillaries. At the same time, waste ions and hydrogen ions pass from the capillaries into the renal tubule. This process is called secretion. The secreted ions combine with the remaining filtrate and become urine. The urine flows out of the nephron tubule into a collecting duct. It passes out of the kidney through the renal pelvis, into the ureter, and down to the bladder.The nephrons of the kidneys process blood and create urine through a process of filtration, reabsorption, and secretion. Urine is about 95% water and 5% waste products. Nitrogenous wastes excreted in urine include urea, creatinine, ammonia, and uric acid. Ions such as sodium, potassium, hydrogen, and calcium are also excreted
Human kidney,structure and functions of kidneyAnand P P
human kidney structural and functions.different types of structural components present in kidney and each structure having definite functions.structural and functional aspects of kidney.
Nephron (The Guyton and Hall physiology)Maryam Fida
Structural and Functional unit of kidney is called nephron.
There are about 1.3 million nephron in each kidney.
New nephrons can not be regenerated by kidneys.
Functioning nephrons decrease about 10 % every 10 years at the age of 40.
At the age of 80, there are 40 % of functioning nephrons as compared to 40 yrs.
It is formed by two parts.
1. GLOMERULUS
2. BOWMAN’S CAPSULE
1- Glomerulus:
It consists of tuft of glomerular capillaries.
There is anastomosing & branching network of glomerular capillaries.
Glomerular capillaries have high hydrostatic pressure (nearly 60 mm Hg) as compared with other capillaries.
Glomerulus is surrounded by a membranous cover called Bowman’s capsule.
Each glomerulus is about 0.2 mm in diameter.
Glomerulus and Bowman’s capsule together constitute renal corpuscle.
Each renal tubule is divided into various part as they have different functions.
i- Proximal convulated tubule.
It is continuation of Bowman’s capsule.
ii- Loop of Henle. It is continuation of prox. conv. tubule.
* Loop of Henle has three parts.
a- descending limb,
b- u turn or bend in medulla and
c- ascending limb.
Ascending limb has initial thin segment followed by thick segment.
At the end of thick ascending limb, there is short segment called macula densa, which plays important role in controlling functions of nephron.
The basics of autoregulation of Gloemrular filtration rate. This ppt deals with basic renal physiology, tubuloglomerular feedback, myogenic reflex, juxtaglomerular apparatus and renin angiotensin aldosterone system in brief. P.S.- The ppt has animations so kindly view in slide/presentation mode
Tubular reabsorption (The Guyton and Hall physiology)Maryam Fida
It is the second step of urine formation.
It is defined as;
“ The process by which water and other substances are transported by renal tubules back to blood is called Tubular Reabsorption”.
Tubular reabsorption is highly selective.
Some substances like glucose and amino acids are completely absorbed from tubules. So, the urinary excretion is zero.
Ions such as Na+, Cl-, HCO3- are highly absorbed but rate of absorption and excretion varies, according to body needs.
Materials Not Reabsorbed
Nitrogenous waste products
Urea
Uric acid
Creatinine
Excess water
The nephron is the microscopic structural and functional unit of the kidney. It is composed of a renal corpuscle and a renal tubule. The renal corpuscle consists of a tuft of capillaries called a glomerulus and an encompassing Bowman's capsule. The renal tubule extends from the capsule.
The basics of autoregulation of Gloemrular filtration rate. This ppt deals with basic renal physiology, tubuloglomerular feedback, myogenic reflex, juxtaglomerular apparatus and renin angiotensin aldosterone system in brief. P.S.- The ppt has animations so kindly view in slide/presentation mode
Tubular reabsorption (The Guyton and Hall physiology)Maryam Fida
It is the second step of urine formation.
It is defined as;
“ The process by which water and other substances are transported by renal tubules back to blood is called Tubular Reabsorption”.
Tubular reabsorption is highly selective.
Some substances like glucose and amino acids are completely absorbed from tubules. So, the urinary excretion is zero.
Ions such as Na+, Cl-, HCO3- are highly absorbed but rate of absorption and excretion varies, according to body needs.
Materials Not Reabsorbed
Nitrogenous waste products
Urea
Uric acid
Creatinine
Excess water
The nephron is the microscopic structural and functional unit of the kidney. It is composed of a renal corpuscle and a renal tubule. The renal corpuscle consists of a tuft of capillaries called a glomerulus and an encompassing Bowman's capsule. The renal tubule extends from the capsule.
AnswerKidneys are the functional units of renal system of rom uri.pdfaquacareser
Answer:
Kidneys are the functional units of renal system of rom urine and it is essential to maintain
homeostasis. Blood is going to enter into the kidney through renal arteries followed by entry of
afferent arterioles into the \"glomerulus of nephrons\" & leave the filtrate (according to
concentration gradient) finally exists as efferent arteriole
Kidneys are the major organs of urinary system. The filtration of blood takes place in the kidneys
through the nephrons. Two ureters carry the urine from the kidneys to the urinary bladder. From
the bladder, urine is excreted out through the urethra. Relatable analogy is presence of \"similar
ureters\" and two bean shaped kidenys with nephrons
The different stages in glomerular filtration or urine formation are.
Filtration: The movement of water and solutes from the plasma into the renal tubules is known as
filtration. The major driving force of the filtration is hydrostatic pressure in the glomerulus
capillaries.
Blood passes through the capillaries in the glomerulus, due to the hydrostatic pressure in the
Bowman’s capsule, plasma is filtered into the Bowman\'s capsule except blood proteins (this is
called ultra-filtration). This filtrate is called glomerular filtrate. Hydrostatic pressure is the
pressure exerted by the filtrate in Bowman\'s capsule (15 mm Hg).
Absorption (or reabsorption):
It is the movement of water and solutes from the renal tubule into the plasma. The process of
absorption mostly occurs in the proximal tubules (approximately 70% of the filtrate is
reabsorbed from the proximal tubules). The process of reabsorption is driven by hydrostatic and
oncotic pressure, which is strictly under hormonal regulation.
Oncotic pressure is the pressure exerted by the blood proteins, which draws water in to the
circulation.
Secretion:
Tubular reabsorption of water and other substances back to the blood occur while the glomerular
filtrate passes through the tubular portion of nephron. About 99% of water and electrolytes are
reabsorbed during this process by both active and passive reabsorption process. During tubular
secretion, substances pass from the blood into renal tubules.
Excretion:
Urine from the renal tubules enter into the collecting duct à Papillary duct à Calyx à Renal pelvis
à Ureters à Urinary bladder à Urethra (excreted out of the body.).
Normal glomerular filtration rate in the Bowman’s capsule is from 90 to 120 ml / min/1.73 m2.
Usually older people do have a bit lower normal GFR levels as it is naturally reduce with age.
Given GFR is 35mL/min/1.73 m2 (moderate decrease), it tells about the patient’s kidney
function that “a sign of chronic kidney disease” because of diabetes, high blood pressure
followed by glomerulonephritis. It is better control blood pressure by hormonal release.
The three stages of urine formation are 1. Filtration; 2. Tubular reabsorption & secretion; 3.
Water conservation
Glomerular filtration (GFR):
The formation of urine includes
1. Glomerular filtration
.
AnswerKidneys are the functional units of renal system of rom uri.pdfaquapariwar
Answer:
Kidneys are the functional units of renal system of rom urine and it is essential to maintain
homeostasis. Blood is going to enter into the kidney through renal arteries followed by entry of
afferent arterioles into the \"glomerulus of nephrons\" & leave the filtrate (according to
concentration gradient) finally exists as efferent arteriole
Kidneys are the major organs of urinary system. The filtration of blood takes place in the kidneys
through the nephrons. Two ureters carry the urine from the kidneys to the urinary bladder. From
the bladder, urine is excreted out through the urethra. Relatable analogy is presence of \"similar
ureters\" and two bean shaped kidenys with nephrons
The different stages in glomerular filtration or urine formation are.
Filtration: The movement of water and solutes from the plasma into the renal tubules is known as
filtration. The major driving force of the filtration is hydrostatic pressure in the glomerulus
capillaries.
Blood passes through the capillaries in the glomerulus, due to the hydrostatic pressure in the
Bowman’s capsule, plasma is filtered into the Bowman\'s capsule except blood proteins (this is
called ultra-filtration). This filtrate is called glomerular filtrate. Hydrostatic pressure is the
pressure exerted by the filtrate in Bowman\'s capsule (15 mm Hg).
Absorption (or reabsorption):
It is the movement of water and solutes from the renal tubule into the plasma. The process of
absorption mostly occurs in the proximal tubules (approximately 70% of the filtrate is
reabsorbed from the proximal tubules). The process of reabsorption is driven by hydrostatic and
oncotic pressure, which is strictly under hormonal regulation.
Oncotic pressure is the pressure exerted by the blood proteins, which draws water in to the
circulation.
Secretion:
Tubular reabsorption of water and other substances back to the blood occur while the glomerular
filtrate passes through the tubular portion of nephron. About 99% of water and electrolytes are
reabsorbed during this process by both active and passive reabsorption process. During tubular
secretion, substances pass from the blood into renal tubules.
Excretion:
Urine from the renal tubules enter into the collecting duct à Papillary duct à Calyx à Renal pelvis
à Ureters à Urinary bladder à Urethra (excreted out of the body.).
Normal glomerular filtration rate in the Bowman’s capsule is from 90 to 120 ml / min/1.73 m2.
Usually older people do have a bit lower normal GFR levels as it is naturally reduce with age.
Given GFR is 35mL/min/1.73 m2 (moderate decrease), it tells about the patient’s kidney
function that “a sign of chronic kidney disease” because of diabetes, high blood pressure
followed by glomerulonephritis. It is better control blood pressure by hormonal release.
The three stages of urine formation are 1. Filtration; 2. Tubular reabsorption & secretion; 3.
Water conservation
Glomerular filtration (GFR):
The formation of urine includes
1. Glomerular filtration
.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/