Presentation made by Dr. Sarah Keedy at the May 28 2014 Live Webinar hosted by the Schizophrenia Forum - Research Domain Criteria (RDoC) Applied to Verbal Hallucinationshttp://schizophreniaforum.org/for/live/detail.asp?liveID=92
Presentation made by Dr. Bruce Cuthbert at the May 28 2014 Live Webinar hosted by the Schizophrenia Forum - Research Domain Criteria (RDoC) Applied to Verbal Hallucinationshttp://schizophreniaforum.org/for/live/detail.asp?liveID=92
Neuro-diagnostic research: a perfect marriageWHY5Research
The document discusses neuro-diagnostic research which combines biometric brain wave measurement via EEG with psychological analysis. It aims to provide objective insights into consumer motivations beyond what traditional qualitative research can determine. The approach is demonstrated through a case study analyzing alternative executions for a funeral insurance company's (DELA) new ad campaign. EEG data from viewers is analyzed using the AERA model to understand attention, emotion, rational processing and affective resonance. Key events in brain activity are identified and interpreted along with diagnostic interviews to evaluate how well each ad fulfills DELA's communication objectives.
Neuro-diagnostic research: the perfect marriage between biology and psychologyWHY5Research
Presentation by Madeleine Janssens (WHY5Research) and Marysia Kluppels (DELA) on how the brain wave measurement tool Evaluate helped DELA to choose the most effective narrative for their tv commercial. The document was presented at the Marketing & Insights Event 2013 in the Netherlands
The Effects of ADHD Symptomology on Sleep draft.final-2Leah Doghramji
This study examined the relationship between ADHD symptomology and sleep problems. The results showed that:
1) Both hyperactive/impulsive and inattentive ADHD symptoms were significantly related to poor sleep quality and efficiency.
2) Inattentive symptoms were also positively correlated with sleep disturbance and insomnia.
3) Hyperactive/impulsive symptoms at Time 1 were related to insomnia at Time 2, but this relationship was accounted for by depressive symptoms, suggesting depression partially mediates this relationship.
4) The findings indicate ADHD symptoms negatively impact sleep, and addressing sleep problems may help manage ADHD symptoms and related depression.
This document outlines a transdiagnostic approach to understanding psychotic symptoms across different diagnoses. It identifies four subtypes of psychotic experiences - highly salient, trauma-related, dreamlike, and isolated symptoms - that can present across conditions like schizophrenia, bipolar disorder, PTSD, and others. Each subtype is associated with different patterns in cognition, perception, and underlying neurobiology. Taking a transdiagnostic approach allows for more homogeneous patient groupings, links symptoms to pathophysiology, and ties pathophysiology to optimized treatment tailored to the specific symptom presentation rather than diagnosis alone.
Presentation made by Dr. Ralph Hoffman at the May 28, 2014 Live Webinar hosted by the Schizophrenia Forum - http://schizophreniaforum.org/for/live/detail.asp?liveID=92
Presentation made at the live webinar hosted by the Schizophrenia Research Forum on the 21st of February, 2017 - http://www.schizophreniaforum.org/forums/treatment-resistant-schizophrenia-new-guidelines-diagnosis-and-terminology
John Kane - Treatment-Resistant Schizophrenia: New Guidelines on Diagnosis an...wef
Presentation made at the live webinar hosted by the Schizophrenia Research Forum on the 21st of February, 2017 - http://www.schizophreniaforum.org/forums/treatment-resistant-schizophrenia-new-guidelines-diagnosis-and-terminology
Presentation made by Dr. Bruce Cuthbert at the May 28 2014 Live Webinar hosted by the Schizophrenia Forum - Research Domain Criteria (RDoC) Applied to Verbal Hallucinationshttp://schizophreniaforum.org/for/live/detail.asp?liveID=92
Neuro-diagnostic research: a perfect marriageWHY5Research
The document discusses neuro-diagnostic research which combines biometric brain wave measurement via EEG with psychological analysis. It aims to provide objective insights into consumer motivations beyond what traditional qualitative research can determine. The approach is demonstrated through a case study analyzing alternative executions for a funeral insurance company's (DELA) new ad campaign. EEG data from viewers is analyzed using the AERA model to understand attention, emotion, rational processing and affective resonance. Key events in brain activity are identified and interpreted along with diagnostic interviews to evaluate how well each ad fulfills DELA's communication objectives.
Neuro-diagnostic research: the perfect marriage between biology and psychologyWHY5Research
Presentation by Madeleine Janssens (WHY5Research) and Marysia Kluppels (DELA) on how the brain wave measurement tool Evaluate helped DELA to choose the most effective narrative for their tv commercial. The document was presented at the Marketing & Insights Event 2013 in the Netherlands
The Effects of ADHD Symptomology on Sleep draft.final-2Leah Doghramji
This study examined the relationship between ADHD symptomology and sleep problems. The results showed that:
1) Both hyperactive/impulsive and inattentive ADHD symptoms were significantly related to poor sleep quality and efficiency.
2) Inattentive symptoms were also positively correlated with sleep disturbance and insomnia.
3) Hyperactive/impulsive symptoms at Time 1 were related to insomnia at Time 2, but this relationship was accounted for by depressive symptoms, suggesting depression partially mediates this relationship.
4) The findings indicate ADHD symptoms negatively impact sleep, and addressing sleep problems may help manage ADHD symptoms and related depression.
This document outlines a transdiagnostic approach to understanding psychotic symptoms across different diagnoses. It identifies four subtypes of psychotic experiences - highly salient, trauma-related, dreamlike, and isolated symptoms - that can present across conditions like schizophrenia, bipolar disorder, PTSD, and others. Each subtype is associated with different patterns in cognition, perception, and underlying neurobiology. Taking a transdiagnostic approach allows for more homogeneous patient groupings, links symptoms to pathophysiology, and ties pathophysiology to optimized treatment tailored to the specific symptom presentation rather than diagnosis alone.
Presentation made by Dr. Ralph Hoffman at the May 28, 2014 Live Webinar hosted by the Schizophrenia Forum - http://schizophreniaforum.org/for/live/detail.asp?liveID=92
Presentation made at the live webinar hosted by the Schizophrenia Research Forum on the 21st of February, 2017 - http://www.schizophreniaforum.org/forums/treatment-resistant-schizophrenia-new-guidelines-diagnosis-and-terminology
John Kane - Treatment-Resistant Schizophrenia: New Guidelines on Diagnosis an...wef
Presentation made at the live webinar hosted by the Schizophrenia Research Forum on the 21st of February, 2017 - http://www.schizophreniaforum.org/forums/treatment-resistant-schizophrenia-new-guidelines-diagnosis-and-terminology
Price, S.L., Mahler, H. IM, & Hopwood, C. J. (2019, April). Development and validation of a self-report scale for measuring subjective emptiness. Oral presentation at the North American Society for the Study of Personality Disorders Annual Conference, Pittsburgh, PA.
This document provides an overview of the psychoanalytic approach to personality proposed by Sigmund Freud. It discusses:
1. Freud's discovery of the unconscious mind and development of psychoanalysis using free association.
2. Freud's structural model of personality consisting of the id, ego, and superego. It also discusses Freud's concepts of libido, thanatos, and defense mechanisms.
3. Freud's psychosexual stages of development including the oral, anal, and phallic stages and how fixation at different stages can influence adult personality.
The document provides a concise introduction to Freud's seminal psychoanalytic theory of personality.
Semantic shifts in mental health-related conceptsNaomi Baes
20-minute Presentation for Workshop: "4th International Workshop on Computational Approaches to Historical Language Change 2023 (LChange ’23)" - December 6 2023, Resorts World Convention Centre, Singapore, Empirical Methods for Natural Language Processing (EMNLP) 2023 Conference
Authors: Naomi Baes, Nick Haslam, Ekaterina Vylomova
Abstract: The present study evaluates semantic shifts in mental health-related concepts in two diachronic corpora spanning 1970-2016, one academic and one general. It evaluates whether their meanings have broadened to encompass less severe phenomena and whether they have become more pathology related. It applies a recently proposed methodology (Baes et al., 2023) to examine whether words collocating with a sample of mental health concepts have become less emotionally intense and develops a new way to examine whether the concepts increasingly co-occur with pathology-related terms. In support of the first hypothesis, mental health-related concepts became associated with less emotionally intense language in the psychology corpus (addiction, anger, stress, worry) and in the general corpus (addiction, grief, stress, worry). In support of the second hypothesis, mental health-related concepts came to be more associated with pathology-related language in psychology (addiction, grief, stress, worry) and in the general corpus (grief, stress). Findings demonstrate that some mental health concepts have become normalized and/or pathologized, a conclusion with important social and cultural implications.
Paper: https://aclanthology.org/2023.lchange-1.13/
This document contains learning objectives and materials for lessons on schizophrenia and research methods in psychology. It includes an application task analyzing a case study of a person named Jack who has schizophrenia. It also provides information on primary and secondary data in research and examples of questions to answer about these topics. Finally, it outlines objectives and materials on the use of twin studies in examining the role of nature and nurture in schizophrenia, including objectives for understanding Gottesman and Shields' twin study on concordance rates.
Week 5 Data Types and Gottesman and Shields 1961Jamie Davies
This document contains learning objectives and materials for lessons on schizophrenia and research methods in psychology. It includes an application task analyzing a case study of a person named Jack who has schizophrenia. It also provides information on primary and secondary data in research and examples of questions to answer about these topics. Finally, it outlines objectives and materials on the use of twin studies in examining the role of nature and nurture in schizophrenia, including objectives for understanding Gottesman and Shields' twin study on the disorder.
This document provides an overview of theories of personality, including Carl Jung's concepts of introversion and extroversion and Hans Eysenck's theory of the biological basis of introversion and extroversion. Eysenck believed that differences in central nervous system functioning, specifically the reticular activating system, underlie personality types, with high ARAS arousal predisposing individuals to introversion and low ARAS arousal to extroversion. The document also discusses research findings related to biological differences between introverts and extroverts and Eysenck's view that biological predispositions interact with environmental factors to shape personality.
By the end of this presentation you should be able to:
Describe what is qualitative research
Demonstrate the differences between Qualitative & Quantitative research
Understand the basic concepts of Qualitative studies:
Characteristics of qualitative research
Bias
Triangulation
Trustworthiness
Schizophrenia is characterized by psychosis, or a loss of contact with reality. It has a prevalence of 1% of the population and is classified into positive and negative symptoms. Positive symptoms include delusions and hallucinations, while negative symptoms involve a reduction in emotions and behaviors. Biological factors like genetics and dopamine levels are thought to contribute to schizophrenia. Treatment involves atypical antipsychotic drugs which target both positive and negative symptoms with fewer side effects than conventional drugs. However, antipsychotics may also have disadvantages like sudden death or involuntary movements.
October 23, 2019
The future of neuroscience and law will be a computational future, as both fields are increasingly integrating artificial intelligence and machine learning. But what will this future look like? Can AI and digital technologies promote justice, diversity, and inclusion? Or will these technologies replicate, or even exacerbate, existing inequalities and biases? In this lunchtime event, leading experts in artificial intelligence, computational psychiatry, and the law discussed these questions as they explored how AI and digital technologies can advance social good through improved social, psychiatric, and legal interventions.
For more information, visit our website at https://petrieflom.law.harvard.edu/events/details/computational-justice
This document discusses screening and assessment for trauma and substance abuse. It emphasizes the importance of screening to prevent misdiagnosis and improve treatment outcomes. The assessment process should determine the nature and extent of a client's problems, clarify expectations, build rapport, and respect personal space and culture. Assessments include clinical interviews, record reviews, and measures, and should be ongoing to update treatment plans. Common myths include thinking substance abuse is itself trauma or that assessing trauma is enough without treatment.
Wellness is something we can develop. These slides include references of papers and books with strategies to develop a healthy mind extracted from the latests discoveries in neuroscience research. www.jorgeserrano.com
The 1st Question - Is there Life after Deathsssagitarius
This document discusses evidence for life after death from a variety of sources, including near-death experiences, past life memories, conversations with mediums and non-physical entities, and scientific studies. It addresses common counterarguments such as the lack of physical evidence for the soul, subjective nature of experiences, brain changes altering personality, and variations in near-death experience accounts. The document provides a framework for evaluating this type of evidence and draws conclusions about the existence of non-physical entities and the potential to measure their presence and activities through scientific instruments.
This document discusses various topics related to forensic science, including whether forensic science is truly a science, cognitive biases that can affect forensic examiners, efforts to introduce quantitative methods and reduce bias, and developments in audio forensics. Specifically, it addresses the scientific method, cognitive biases, likelihood ratios as a quantitative measure, blind testing techniques, and the analysis of voiceprints in audio forensics cases.
The document discusses the reliability of diagnoses made using the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I). It reports that reliability is measured using kappa values and provides a table summarizing reliability statistics from several studies using the SCID-I. The table shows a wide range of kappa values for different diagnoses. The document notes several factors that can influence reliability scores, such as the study design, interviewer training, characteristics of the subject population, and base rates of diagnoses.
Intelligence involves the capacity to learn and adapt to one's environment, and theories of intelligence propose both general factors of intelligence as well as multiple intelligences. Research finds that intelligence is influenced by both genetic and environmental factors, with twin and adoption studies estimating heritability accounts for 30-75% of differences in intelligence. Larger brain size is correlated with higher intelligence, and environmental factors like education and nutrition can also impact intellectual development.
Eske Derks commentary - SRF webinar "Is Schizophrenia Dead Yet?"wef
Schizophrenia patients are qualitatively different from their healthy siblings and controls based on genetic studies. While there is some genetic overlap between schizophrenia, psychosis, and general mental health risk, distinct genetic factors for schizophrenia have also been found. Specifically, over 200 genetic risk factors for schizophrenia have been identified. Based on these genetic findings, the presenter concludes that schizophrenia is not simply an extreme on a normal distribution of traits and replacing it with a psychosis spectrum disorder would be premature.
This document provides an overview of several theories of personality, including psychodynamic, trait, humanistic, social-cognitive, cultural, and biological theories. It discusses key concepts from each approach, such as Freud's structural model of the id, ego, and superego; Jung's collective unconscious and archetypes; the Big Five personality traits; Rogers' humanistic perspective on genuineness, acceptance, and empathy; Bandura's social-cognitive theory of reciprocal determinism; individualism vs collectivism in cultural influences; and biological factors like brain damage, neurochemistry, and genetics that influence personality. The document also evaluates the scientific merits and limitations of different theories.
Robin Murray commentary during the SRF webinar "Is Schizophrenia Dead Yet?"wef
Schizophrenia is not a single disease but rather two different syndromes according to the DSM-5 and ICD-10 diagnostic criteria, with only 70% of patients meeting criteria for both. This raises questions about what to call patients who meet one but not the other and how useful the term "schizophrenia" is given the lack of biological markers and different interpretations by psychiatrists. Looking at dimensions of psychosis symptoms, predominant causes, and severity/persistence may provide more helpful information to patients and their outcomes than the term schizophrenia.
Jim van Os presentation during SRF live webinar "Is Schizophrenia Dead Yet?"wef
This document discusses the debate around schizophrenia diagnoses and proposes an alternative psychosis spectrum syndrome approach. It summarizes that the debate is about clinical diagnosis, not research criteria. It also notes that around 3.5% of people experience some form of psychosis, but the current system publishes overwhelmingly on only one category, schizophrenia. The document advocates for recognizing a spectrum approach and dimensional personal diagnoses within a categorical psychosis spectrum to better reflect individuals' experiences and needs.
Price, S.L., Mahler, H. IM, & Hopwood, C. J. (2019, April). Development and validation of a self-report scale for measuring subjective emptiness. Oral presentation at the North American Society for the Study of Personality Disorders Annual Conference, Pittsburgh, PA.
This document provides an overview of the psychoanalytic approach to personality proposed by Sigmund Freud. It discusses:
1. Freud's discovery of the unconscious mind and development of psychoanalysis using free association.
2. Freud's structural model of personality consisting of the id, ego, and superego. It also discusses Freud's concepts of libido, thanatos, and defense mechanisms.
3. Freud's psychosexual stages of development including the oral, anal, and phallic stages and how fixation at different stages can influence adult personality.
The document provides a concise introduction to Freud's seminal psychoanalytic theory of personality.
Semantic shifts in mental health-related conceptsNaomi Baes
20-minute Presentation for Workshop: "4th International Workshop on Computational Approaches to Historical Language Change 2023 (LChange ’23)" - December 6 2023, Resorts World Convention Centre, Singapore, Empirical Methods for Natural Language Processing (EMNLP) 2023 Conference
Authors: Naomi Baes, Nick Haslam, Ekaterina Vylomova
Abstract: The present study evaluates semantic shifts in mental health-related concepts in two diachronic corpora spanning 1970-2016, one academic and one general. It evaluates whether their meanings have broadened to encompass less severe phenomena and whether they have become more pathology related. It applies a recently proposed methodology (Baes et al., 2023) to examine whether words collocating with a sample of mental health concepts have become less emotionally intense and develops a new way to examine whether the concepts increasingly co-occur with pathology-related terms. In support of the first hypothesis, mental health-related concepts became associated with less emotionally intense language in the psychology corpus (addiction, anger, stress, worry) and in the general corpus (addiction, grief, stress, worry). In support of the second hypothesis, mental health-related concepts came to be more associated with pathology-related language in psychology (addiction, grief, stress, worry) and in the general corpus (grief, stress). Findings demonstrate that some mental health concepts have become normalized and/or pathologized, a conclusion with important social and cultural implications.
Paper: https://aclanthology.org/2023.lchange-1.13/
This document contains learning objectives and materials for lessons on schizophrenia and research methods in psychology. It includes an application task analyzing a case study of a person named Jack who has schizophrenia. It also provides information on primary and secondary data in research and examples of questions to answer about these topics. Finally, it outlines objectives and materials on the use of twin studies in examining the role of nature and nurture in schizophrenia, including objectives for understanding Gottesman and Shields' twin study on concordance rates.
Week 5 Data Types and Gottesman and Shields 1961Jamie Davies
This document contains learning objectives and materials for lessons on schizophrenia and research methods in psychology. It includes an application task analyzing a case study of a person named Jack who has schizophrenia. It also provides information on primary and secondary data in research and examples of questions to answer about these topics. Finally, it outlines objectives and materials on the use of twin studies in examining the role of nature and nurture in schizophrenia, including objectives for understanding Gottesman and Shields' twin study on the disorder.
This document provides an overview of theories of personality, including Carl Jung's concepts of introversion and extroversion and Hans Eysenck's theory of the biological basis of introversion and extroversion. Eysenck believed that differences in central nervous system functioning, specifically the reticular activating system, underlie personality types, with high ARAS arousal predisposing individuals to introversion and low ARAS arousal to extroversion. The document also discusses research findings related to biological differences between introverts and extroverts and Eysenck's view that biological predispositions interact with environmental factors to shape personality.
By the end of this presentation you should be able to:
Describe what is qualitative research
Demonstrate the differences between Qualitative & Quantitative research
Understand the basic concepts of Qualitative studies:
Characteristics of qualitative research
Bias
Triangulation
Trustworthiness
Schizophrenia is characterized by psychosis, or a loss of contact with reality. It has a prevalence of 1% of the population and is classified into positive and negative symptoms. Positive symptoms include delusions and hallucinations, while negative symptoms involve a reduction in emotions and behaviors. Biological factors like genetics and dopamine levels are thought to contribute to schizophrenia. Treatment involves atypical antipsychotic drugs which target both positive and negative symptoms with fewer side effects than conventional drugs. However, antipsychotics may also have disadvantages like sudden death or involuntary movements.
October 23, 2019
The future of neuroscience and law will be a computational future, as both fields are increasingly integrating artificial intelligence and machine learning. But what will this future look like? Can AI and digital technologies promote justice, diversity, and inclusion? Or will these technologies replicate, or even exacerbate, existing inequalities and biases? In this lunchtime event, leading experts in artificial intelligence, computational psychiatry, and the law discussed these questions as they explored how AI and digital technologies can advance social good through improved social, psychiatric, and legal interventions.
For more information, visit our website at https://petrieflom.law.harvard.edu/events/details/computational-justice
This document discusses screening and assessment for trauma and substance abuse. It emphasizes the importance of screening to prevent misdiagnosis and improve treatment outcomes. The assessment process should determine the nature and extent of a client's problems, clarify expectations, build rapport, and respect personal space and culture. Assessments include clinical interviews, record reviews, and measures, and should be ongoing to update treatment plans. Common myths include thinking substance abuse is itself trauma or that assessing trauma is enough without treatment.
Wellness is something we can develop. These slides include references of papers and books with strategies to develop a healthy mind extracted from the latests discoveries in neuroscience research. www.jorgeserrano.com
The 1st Question - Is there Life after Deathsssagitarius
This document discusses evidence for life after death from a variety of sources, including near-death experiences, past life memories, conversations with mediums and non-physical entities, and scientific studies. It addresses common counterarguments such as the lack of physical evidence for the soul, subjective nature of experiences, brain changes altering personality, and variations in near-death experience accounts. The document provides a framework for evaluating this type of evidence and draws conclusions about the existence of non-physical entities and the potential to measure their presence and activities through scientific instruments.
This document discusses various topics related to forensic science, including whether forensic science is truly a science, cognitive biases that can affect forensic examiners, efforts to introduce quantitative methods and reduce bias, and developments in audio forensics. Specifically, it addresses the scientific method, cognitive biases, likelihood ratios as a quantitative measure, blind testing techniques, and the analysis of voiceprints in audio forensics cases.
The document discusses the reliability of diagnoses made using the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I). It reports that reliability is measured using kappa values and provides a table summarizing reliability statistics from several studies using the SCID-I. The table shows a wide range of kappa values for different diagnoses. The document notes several factors that can influence reliability scores, such as the study design, interviewer training, characteristics of the subject population, and base rates of diagnoses.
Intelligence involves the capacity to learn and adapt to one's environment, and theories of intelligence propose both general factors of intelligence as well as multiple intelligences. Research finds that intelligence is influenced by both genetic and environmental factors, with twin and adoption studies estimating heritability accounts for 30-75% of differences in intelligence. Larger brain size is correlated with higher intelligence, and environmental factors like education and nutrition can also impact intellectual development.
Eske Derks commentary - SRF webinar "Is Schizophrenia Dead Yet?"wef
Schizophrenia patients are qualitatively different from their healthy siblings and controls based on genetic studies. While there is some genetic overlap between schizophrenia, psychosis, and general mental health risk, distinct genetic factors for schizophrenia have also been found. Specifically, over 200 genetic risk factors for schizophrenia have been identified. Based on these genetic findings, the presenter concludes that schizophrenia is not simply an extreme on a normal distribution of traits and replacing it with a psychosis spectrum disorder would be premature.
This document provides an overview of several theories of personality, including psychodynamic, trait, humanistic, social-cognitive, cultural, and biological theories. It discusses key concepts from each approach, such as Freud's structural model of the id, ego, and superego; Jung's collective unconscious and archetypes; the Big Five personality traits; Rogers' humanistic perspective on genuineness, acceptance, and empathy; Bandura's social-cognitive theory of reciprocal determinism; individualism vs collectivism in cultural influences; and biological factors like brain damage, neurochemistry, and genetics that influence personality. The document also evaluates the scientific merits and limitations of different theories.
Similar to Keedy RdoC multidimensional avhfinal (20)
Robin Murray commentary during the SRF webinar "Is Schizophrenia Dead Yet?"wef
Schizophrenia is not a single disease but rather two different syndromes according to the DSM-5 and ICD-10 diagnostic criteria, with only 70% of patients meeting criteria for both. This raises questions about what to call patients who meet one but not the other and how useful the term "schizophrenia" is given the lack of biological markers and different interpretations by psychiatrists. Looking at dimensions of psychosis symptoms, predominant causes, and severity/persistence may provide more helpful information to patients and their outcomes than the term schizophrenia.
Jim van Os presentation during SRF live webinar "Is Schizophrenia Dead Yet?"wef
This document discusses the debate around schizophrenia diagnoses and proposes an alternative psychosis spectrum syndrome approach. It summarizes that the debate is about clinical diagnosis, not research criteria. It also notes that around 3.5% of people experience some form of psychosis, but the current system publishes overwhelmingly on only one category, schizophrenia. The document advocates for recognizing a spectrum approach and dimensional personal diagnoses within a categorical psychosis spectrum to better reflect individuals' experiences and needs.
Rene Kahn commentary during SRF Live Webinar: "Is Schizophrenia Dead Yet?wef
Schizophrenia and bipolar disorder are distinct conditions with little genetic overlap and different risk factors. Schizophrenia is primarily a cognitive disorder, not defined by psychosis, as cognitive decline precedes psychotic episodes. While some wish to deny the poor prognosis of schizophrenia, studies show the disorder leads to reduced life expectancy, high suicide and unemployment rates, and long-term functional impairment for most patients.
NIMH i PSC Assays for the Drug Pipeline - Panchisionwef
Dr David Panchision's live presentation at the Schizophrenia Research Forum's live webinar of June 28, 2017 - http://www.schizophreniaforum.org/forums/webinar-modeling-neuropsychiatric-disorders-using-vitro-models
Schizophrenia Research Forum Live Webinar - June 28, 2017 - Rusty Gage wef
1) The document describes a study using induced pluripotent stem cells (iPSCs) derived from bipolar disorder (BD) patients to model the disease in vitro.
2) Hippocampal dentate gyrus-like neurons were differentiated from iPSCs and showed hyper-excitability at both the molecular and functional levels in BD-derived neurons.
3) Treatment with lithium rescued the hyper-excitability phenotype in neurons derived from lithium-responsive BD patients but not lithium non-responsive patients, suggesting patient-specific responses.
SCHIZOPHRENIA RESEARCH FORUM - LIVE WEBINAR June 2017 Kristen Brennandwef
Kristen Brennand presentation at the live webinar of June 28, 2017 hosted by the Schizophrenia Research Forum (http://www.schizophreniaforum.org/forums/webinar-modeling-neuropsychiatric-disorders-using-vitro-models)
STRATEGIES FOR COMMUNICATION AND SENSITIVITY FOR PERSONS EXPERIENCING DEMENTI...wef
This document summarizes a workshop on strategies for communicating with persons experiencing dementia. It discusses how communication is impacted at different stages of dementia from early to late stage. In early stage, word retrieval becomes difficult. In middle stage, language abilities further decline making conversation challenging. In late stage, communication is limited but sensory stimulation through touch, sound, and smell can still connect a person. The workshop provides guidance on adapting approaches to best communicate with someone based on their stage of dementia.
Translating from Animal Models to Human Schizophrenia - Insights into Pathoph...wef
Presentation made by Dr. Tony Grace at the Schizophrenia Research Forum's live webinar of May 4, 2017 - Dopamine in Schizophrenia—Cortical and Subcortical Pathophysiology - review recording of session at http://www.schizophreniaforum.org/forums/dopamine-schizophrenia%E2%80%94cortical-and-subcortical-pathophysiology
Presentation made by Dr. Oliver Howes at the Schizophrenia Research Forum's live webinar of May 4, 2017 - Dopamine in Schizophrenia—Cortical and Subcortical Pathophysiology - review recording of session at http://www.schizophreniaforum.org/forums/dopamine-schizophrenia%E2%80%94cortical-and-subcortical-pathophysiology
Topography and functional significance of the dopaminesgic dysfunction in sch...wef
Presentation made by Dr. Anissa Abi-Dargham at the Schizophrenia Research Forum's live webinar of May 4, 2017 - Dopamine in Schizophrenia—Cortical and Subcortical Pathophysiology - review recording of session at http://www.schizophreniaforum.org/forums/dopamine-schizophrenia%E2%80%94cortical-and-subcortical-pathophysiology
SRF Webinar - What It Will Take to Make Coordinated Specialty Care Available ...wef
Presentation made March 22, 2017, during the live webinar hosted by Schizophrenia Research Forum (SRF). Event recording and additional slides at http://www.schizophreniaforum.org/forums/achieving-effective-treatment-early-psychosis-united-states
SRF Webinar: Beyond DUP - Addressing Disengagement in Community-based Early I...wef
Presentation made March 22, 2017, during the live webinar hosted by Schizophrenia Research Forum (SRF). Event recording and additional slides at http://www.schizophreniaforum.org/forums/achieving-effective-treatment-early-psychosis-united-states
This document provides an overview of memory loss, dementia, and Alzheimer's disease. It defines key terms, describes symptoms at different stages of dementia, and discusses a person-centered approach to care. The main points are:
1) Dementia is not a specific disease but a general term for symptoms caused by various brain disorders, while Alzheimer's disease is the most common cause of progressive dementia.
2) Early stage dementia symptoms include memory loss, impaired judgment, and difficulty completing tasks, while middle and late stage symptoms involve greater impairment and dependence on others for care.
3) A person-centered approach focuses on maintaining an individual's dignity, independence, and identity through techniques like validation, respect, and personalized
Oliver Howes - Treatment-Resistant Schizophrenia: New Guidelines on Diagnosis...wef
Presentation made at the live webinar hosted by the Schizophrenia Research Forum on the 21st of February, 2017 - http://www.schizophreniaforum.org/forums/treatment-resistant-schizophrenia-new-guidelines-diagnosis-and-terminology
HEAR approach to behavior management Live webinar Feb 1 2017wef
Slides presented at the HEAR Approach to Behavior Management live webinar of February 1, 2017, featuring presentations from Dr. Andrew Heck and Carol Garby.
Live webinar recorded September 7, 2016, hosted by the Lewy Body Dementia Association (www.lbda.org), featuring Dr. James Leverenz and moderated by Angela Taylor.
Review recording and more information at www.lbda.org or at the event page: www.worldeventsforum.net/lbda
1. The document summarizes an orientation for DSS instructors, with panels discussing the previous semesters, upcoming fall courses, and addressing ageism.
2. Spring/Summer 2016 course offerings and attendance rates are reviewed. Instructors share their experiences and questions.
3. The fall 2016 curriculum is outlined, covering infection prevention, person-centered care, avoiding ageism, social isolation, bullying, and working with families.
4. A discussion on disrupting ageism encourages recognizing one's own attitudes, correcting myths, and using non-ageist language. An activity reflects on aging perspectives.
Carrie Bearden: Studying Psychosis in 22q11 Deletion Syndromewef
Presentation made at the live webinar hosted by Schizophrenia Research Forum on the 28th of July, 2016, titled Studying Psychosis in 22q11 Deletion Syndrome. Additional recording and materials available at the SRF website: http://www.schizophreniaforum.org/for/live/detail.asp?liveID=100
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
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1. The Multidimensional
Nature of Auditory
Hallucinations
Sarah K. Keedy, Ph.D.
Assistant Professor of Psychiatry and Behavioral Neuroscience
Director, Cognition and Emotion Neuroscience Lab
University of Chicago
2. 1. Different neural system sets likely lead to hallucinations
– Analogous to fever
– Between group variability
– Within group variability
– Varying “severity”
2. Empirical work endeavoring rational measurement of
hallucinatory experience confirms and unravels multiple
facets of hallucinatory experience
Using the latter (#2) to inform the former (#1) is a needed
research direction and fits RDoC framework
Auditory Hallucinations Are Complex and Varied
Language
network
Salience network Emotion
regulation …
Sarah Keedy, PhD
05.28.2014
3. The PSYRATS(AH)
• The gold standard AH severity scale
• AH scale is 11 items scored 0-4 on the basis of an interview
• Total score range of 0-44
Sarah Keedy, PhD
05.28.2014
4. Dimensions of Auditory Hallucinations
in PSYRATS(AH)
3 factorsa,b
1. Emotional
• Amount negative content
• Degree of negative
content
• Frequency of distress
• Intensity of distress
2. Physical
• Frequency
• Duration
• Loudness
3. Cognitive
• Location
• Origin beliefs
• Disruption
• Control
4 factorsc,d
1. Emotional
• Amount negative content
• Degree of negative
content
• Frequency of distress
• Intensity of distress
2. Physical
• Frequency
• Duration
3. Cognitive
• Location
• Origin beliefs
4. Control
• Loudness
• Disruption
• Control
4(ish) factors e
1. Emotional (Distress)
• Amount negative content
• Degree of negative
content
• Frequency of distress
• Intensity of distress
• Control
2. Physical (Frequency)
• Frequency
• Duration
• Disruption
3. Cognitive (Attribution)
• Location
• Origin beliefs
4. Loudness
a) Haddock et al., 1999, Psychol Med
b) Drake et al., 2007, Schizophr Res
c) Kronmuller et al., 2011, Compr Psychiatry
d) Steele et al., 2007, Int J Methods Psychiatr Res
e) *Woodward et al. (in press) Schiz Bull
5. Mapping the Emotional Factor to RDoC
Emotional Factor
• Amount of negative content
• Degree of negative content
• Frequency of distress
• Intensity of distress
Suggested RDoC Domain:
Negative Valence
Domain constructs:
Acute Threat
Sustained Threat
http://www.nimh.nih.gov/research-priorities/rdoc/rdoc-constructs.shtml#sustained_threat
6. Mapping the Physical Factor to RDoC
Physical Factor
• Frequency
• Duration
• Loudness
• Disruption
Suggested RDoC Domain:
Cognitive Systems
Suggested constructs:
Perception
subconstructs: Auditory
Attention
Language
Cognitive Control
http://www.nimh.nih.gov/research-priorities/rdoc/rdoc-constructs.shtml#auditory_perception