Drought conditions are affecting parts of East Africa, while diseases are spreading among livestock. Frequent crises negatively impact people's ability to cope with shocks, and short-term aid fails to address the underlying issues. Over 26.8 million people in East and Southern Africa are affected by natural disasters each year, in addition to 10.8 million affected by conflict. Flagship Program 4 of the International Crops Research Institute for the Semi-Arid Tropics aims to understand the impacts of stress and aid on agricultural and social systems to improve interventions before, during, and after crises and promote increased resilience, and it needs research from Flagship Program 1 on long-term drivers of change to help achieve these goals.