Trina Histon, Aubrey Kraft, W. Scott Heisler, Kaiser Permanente Care Manageme...Mad*Pow
How Kaiser Permanente is using human centered design to help members understand and improve their emotional health
In this session you will learn:
One
We will share key insights from our journey to stand up an ecosystem for emotional health and wellness with digital therapeutics in multiple care settings and ‘self-serve’ access to these tools and resources on our patient facing portal.
Two
We will also share our learnings on the application of human centered design to mental health, our preliminary data and insights on the development of a digital therapeutic formulary for emotional health and wellness and key takeaways we have so far on what it takes to integrate these tools across clinical pathways.
Three
Understand how human centered methods map to health literacy
Mental Diseases are more common than cancer, diabetes or heart diseases. However it's often under recognized and stigmatized. Hopefully in 2015 some entrepreneurs are trying to tackle this field in an innovative way.
Santovia's innovative education support tool enables users to make the best healthcare decisions, employers benefit from a solution that supports employees and helps reduce overall costs and insurance.
Trina Histon, Aubrey Kraft, W. Scott Heisler, Kaiser Permanente Care Manageme...Mad*Pow
How Kaiser Permanente is using human centered design to help members understand and improve their emotional health
In this session you will learn:
One
We will share key insights from our journey to stand up an ecosystem for emotional health and wellness with digital therapeutics in multiple care settings and ‘self-serve’ access to these tools and resources on our patient facing portal.
Two
We will also share our learnings on the application of human centered design to mental health, our preliminary data and insights on the development of a digital therapeutic formulary for emotional health and wellness and key takeaways we have so far on what it takes to integrate these tools across clinical pathways.
Three
Understand how human centered methods map to health literacy
Mental Diseases are more common than cancer, diabetes or heart diseases. However it's often under recognized and stigmatized. Hopefully in 2015 some entrepreneurs are trying to tackle this field in an innovative way.
Santovia's innovative education support tool enables users to make the best healthcare decisions, employers benefit from a solution that supports employees and helps reduce overall costs and insurance.
In this webinar, you will learn:
How we approach intervention campaigns: a framework
The science of behavior change and how it can be applied to increase the probability of desired outcomes
How Altarum’s ACE Measure can help predict consumer behaviors and design successful intervention campaigns
Speakers:
Ryan Rossier, Medullan
Chris Duke, Altarum
Josh Klapow, ChipRewards
Upping the "Total" in Total Rewards. Incentivizing your employees with the most sophisticated wearable technology, measuring more biomarkers than any other device, and the only device meriting being reviewed as a medical device. Included in the cost of the device - customized wellness programs designed on your employees biometrics. Our commitment to provide the most personalized corporate wellness programs, at the most affordable price and everyone gets the ultimate wearable technology. We will happily help you design a true program of reward - employee/employer contribution - rewarding commitment and motivation.
Gamification and Global Health ChallengesDavid Wortley
Global Health Challenges such as Obesity, Diabetes, Pandemics and antibiotic-resistant viruses present a real and present danger, not just for the future of national health service provision, but also, arguably, for the future of mankind. This presentation, delivered at the Segamed 2015 conference in Nice in December 2015 focuses primarily on lifestyle related conditions such as obesity. The presentation makes the argument for a collaborative approach from all sectors of society and that the medical profession alone cannot be expected to provide solutions for problems which are essentially self-inflicted.
The presentation looks at the combination of gamification and enabling technologies and, using the analogy of a car, suggests that the human body is our vehicle for taking us through life's journey. Using technology to monitor the condition of our body and developing tools which give us the equivalent of a human sat-nav for our life journey can help to shift responsibility and power for health management towards the citizen and the communities in which we exist.
The MIT Enterprise Forum of Cambridge gathered together a crowd on March 29, 2017 at the Broad Institute to hear about some of the most exciting wearable technologies on the front wave of transformation in healthcare.
From devices that measure brain activity and track workouts, to systems that stimulate muscles to minimize workouts, to body sensors and voice-activated collaborative care solutions that help improve patient engagement and quality of care, the possibilities are near endless.
Please note not all slides presented at the live event are available here, per the request of the presenting companies.
For more information about the MIT Enterprise Forum of Cambridge and all of our programs, please visit: www.mitforumcanbridge.org
International Health Policy and Practice: Comparing the U.S. and Canada on Ac...The Commonwealth Fund
Dr. Eric Schneider's presentation on international health policy and practice. This presentation was delivered at the 2015 AcademyHealth Annual Research Meeting on June 14, 2015.
Making happier, healthier patients
The link between happiness and health is well documented. More accurately referred to as subjective wellbeing, it’s been demonstrated that a positive outlook is
not only the result of good health, but the cause of it.
HCLT Case Study: Gamification in Chronic Disease (ADHD) Treatment HCL Technologies
This slider presentation speaks about HCL’s differentiated approach to managing and assisting treatment of chronic ailments, viz., ADHD/ADD leveraging gamification concepts enabled by mobile technology
Data drives company outcomes - employers agree analytics are a key factor in strategic planning. Customizing wellness solutions that has turned science fiction into science. Employees biometrics and genomics - sequencing the genome - drives choosing individualized wellness coaching. Health solutions - providing a path of sustainability and adherence - scientific, engaging, redefining individualized - And we make it affordable. Employee health programs - what a wonderful way to build healthier communities - establish lifestyle habits creating a healthier future for our children. We can manage & prevent chronic illnesses - saving lives and money - investing the money for happier, bigger, better futures.
New Ideas on the Future of Healthcare at WebVisions PDXElizabeth Bacon
This is a super-quickie presentation given as part of a panel where I introduce some of my recent thoughts about the role of design with respect to the future of healthcare.
In this webinar, you will learn:
How we approach intervention campaigns: a framework
The science of behavior change and how it can be applied to increase the probability of desired outcomes
How Altarum’s ACE Measure can help predict consumer behaviors and design successful intervention campaigns
Speakers:
Ryan Rossier, Medullan
Chris Duke, Altarum
Josh Klapow, ChipRewards
Upping the "Total" in Total Rewards. Incentivizing your employees with the most sophisticated wearable technology, measuring more biomarkers than any other device, and the only device meriting being reviewed as a medical device. Included in the cost of the device - customized wellness programs designed on your employees biometrics. Our commitment to provide the most personalized corporate wellness programs, at the most affordable price and everyone gets the ultimate wearable technology. We will happily help you design a true program of reward - employee/employer contribution - rewarding commitment and motivation.
Gamification and Global Health ChallengesDavid Wortley
Global Health Challenges such as Obesity, Diabetes, Pandemics and antibiotic-resistant viruses present a real and present danger, not just for the future of national health service provision, but also, arguably, for the future of mankind. This presentation, delivered at the Segamed 2015 conference in Nice in December 2015 focuses primarily on lifestyle related conditions such as obesity. The presentation makes the argument for a collaborative approach from all sectors of society and that the medical profession alone cannot be expected to provide solutions for problems which are essentially self-inflicted.
The presentation looks at the combination of gamification and enabling technologies and, using the analogy of a car, suggests that the human body is our vehicle for taking us through life's journey. Using technology to monitor the condition of our body and developing tools which give us the equivalent of a human sat-nav for our life journey can help to shift responsibility and power for health management towards the citizen and the communities in which we exist.
The MIT Enterprise Forum of Cambridge gathered together a crowd on March 29, 2017 at the Broad Institute to hear about some of the most exciting wearable technologies on the front wave of transformation in healthcare.
From devices that measure brain activity and track workouts, to systems that stimulate muscles to minimize workouts, to body sensors and voice-activated collaborative care solutions that help improve patient engagement and quality of care, the possibilities are near endless.
Please note not all slides presented at the live event are available here, per the request of the presenting companies.
For more information about the MIT Enterprise Forum of Cambridge and all of our programs, please visit: www.mitforumcanbridge.org
International Health Policy and Practice: Comparing the U.S. and Canada on Ac...The Commonwealth Fund
Dr. Eric Schneider's presentation on international health policy and practice. This presentation was delivered at the 2015 AcademyHealth Annual Research Meeting on June 14, 2015.
Making happier, healthier patients
The link between happiness and health is well documented. More accurately referred to as subjective wellbeing, it’s been demonstrated that a positive outlook is
not only the result of good health, but the cause of it.
HCLT Case Study: Gamification in Chronic Disease (ADHD) Treatment HCL Technologies
This slider presentation speaks about HCL’s differentiated approach to managing and assisting treatment of chronic ailments, viz., ADHD/ADD leveraging gamification concepts enabled by mobile technology
Data drives company outcomes - employers agree analytics are a key factor in strategic planning. Customizing wellness solutions that has turned science fiction into science. Employees biometrics and genomics - sequencing the genome - drives choosing individualized wellness coaching. Health solutions - providing a path of sustainability and adherence - scientific, engaging, redefining individualized - And we make it affordable. Employee health programs - what a wonderful way to build healthier communities - establish lifestyle habits creating a healthier future for our children. We can manage & prevent chronic illnesses - saving lives and money - investing the money for happier, bigger, better futures.
New Ideas on the Future of Healthcare at WebVisions PDXElizabeth Bacon
This is a super-quickie presentation given as part of a panel where I introduce some of my recent thoughts about the role of design with respect to the future of healthcare.
American Heart Association Lifestyle Recommendations to Redu.docxSusanaFurman449
American Heart Association Lifestyle Recommendations to Reduce Obesity
Yuritza Medina
Chamberlain College of Nursing
NR709 Project and Practicum IV
Summer 2022
Abstract Past tense
The prevalence of obesity and sedentary lifestyle complications are increasing at alarming rates, representing a common but preventable cause of severe medical complications like diabetes, cardiovascular diseases, and early mortality. This common but chronic condition has been for a long time a public health concern and social determinant. The integrative review focused on how the American Heart Association (AHA) Diet and Lifestyle recommendations and the Fitbit app are used as innovative solutions to reduce obesity in adult patients. The Fitbit app offers a unique opportunity to enhance the efficacy of weight loss plans, as it is used to track activity, monitor steps, heart rate, energy expenditure, sleep, and sedentary behavior.
Research Methodology: A systematic review was conducted to identify research articles completed in the preceding 4-5 years centered on obesity care, diet, physical activity, activity trackers, and lifestyle implications. The databases searched were Chamberlain Library, PubMed, and CINHAL.
Results and Discussion: Initial searches yielded over 2000 articles, of which 45 were chosen and examined because they fit the integrative review's theme. The 15 papers most relevant to the PICOT question were studied in further detail and appraised using the Johns Hopkins Evidence Appraisal table. The studies reported positive physical activity outcomes. What were the key themes?
Conclusions and Further Recommendations:This systematic review supported the effectiveness of the AHA Diet and Lifestyle recommendations to prevent and reduce obesity, and clinical use is recommended. Fitbit app provides new ways to improve physical activity habits, and the easy availability of electronic devices may enhance their generalizability use.
Keywords: Obesity care; Obesity complications; Lifestyle recommendations; Obesity management; Physical activity intervention using Fitbit activity trackers.
Dedication
In dedication to my family for their steadfast support of this project; their cooperation means a lot to me. To my husband Armando, thank you for your love, understanding, and patience during this time. I credit my achievement to all of you for your unwavering love and belief in me.
Acknowledgments
First, I must acknowledge the help of all my professors from Chamberlain University, who inspired, encouraged, and supported me throughout the DNP program. My heartfelt thanks to my teammates, without whom I would never have completed this phase in my life. Their encouragement has had a significant influence on my strong determination during this trip.
Contents
American Heart Association Lifestyle Recommendations to Reduce Obesity 1
Abstract 2
Dedication 3
Acknowledgments 4
Introductio.
Most population health webinars focus on topics like chronic disease management, closing care gaps, and the role of preventive care. While these are important concerns, we want you to rethink the meaning of population health and why it’s so important right now. After years of saying value-based care is coming, Dr. Will Caldwell, a physician with 19 years of experience and the Senior Vice President for Population Health at Health Catalyst, will make the case that emerging trends are enabling the true shift to population health.
In this webinar, Dr. Caldwell will offer the following:
• Create excitement about your role in helping others live healthier lives.
• Raise awareness of the opportunity facing us.
• Help us understand the role private equity is playing.
• Encourage us to rethink how we source and use data.
• Explain the transition from disease management to population health management.
• Discuss the largest unrealized opportunity in managing the total cost of care and driving better outcomes.
ILC-UK and the Actuarial Profession Debate: The Economics of Promoting Person...ILC- UK
ILC-UK is delighted to be working with Alliance Boots and the University College London School of Pharmacy to explore why public health has just got ‘personal’ and if such a trend will yield cost savings or cost some groups of society or sections of the economy more than others.
The event will also mark the launch of a report produced by Professor David Taylor and Dr Jennifer Gill from the UCL School of Pharmacy, supported by Alliance Boots entitled ‘Active Ageing: Live longer and prosper? Towards realising a second demographic dividend in 21st century Europe’.
The debate will focus on the balance between encouraging individual accountability and accepting collective responsibility for achieving longer lives and the consequent implications for health outcomes and cost.
The Coalition Government (like its predecessors) is trying to move away from the ‘nanny state’ towards ‘nudging’ people in the direction of choosing healthier behaviours.
Few people would question the desirability of encouraging more informed personal decision making to prevent avoidable illness. But too much reliance on individual choice and responsibility could fail those most at risk and potentially impose needless costs and losses on individuals, their families and the wider community. Promoting the behavioural and cultural changes needed to deliver better public health and keep NHS and social care costs as affordable as possible remains a pressing and complex challenge.
Subject areas to discuss will include:
The philosophical and political underpinnings of public health policy, including: social solidarity, fairness, entitlement, risk and personal responsibility. Are we in danger of unravelling the principle tenets of the Beveridge model welfare state in ways which may not only disadvantage the most vulnerable, but may in time increase financial pressures on other sectors of society?
Determining the boundaries of personal and societal level responsibility, and the legitimate as opposed to illegitimate need for publicly funded care and support. In areas ranging from smoking cessation to reducing the threat of an obesity driven diabetes epidemic, communities have to make tough choices between limiting risks and accepting the consequences of personal, social and corporate freedom.
The impact of current trends and possible future policy decisions in areas ranging from the costs of health and life insurance to the price of pensions for individuals and society.
The role of private employers in promoting and requiring healthy living.
The winners and losers if the trend towards personal responsibility continues, with particular regard to older people and disadvantaged groups and what impact could this trend have on the cost of care?
Agenda from the event
16:00
Registration
16:30
Welcome, Baroness Sally Greengross
16:40 – 18:25
Presentations and responses from:
Prof. David Taylor
Prof. Nick Bosaonquet
Tricia Kennerley
Martin Green
Improving quality of care, using existing assets better and reducing medical ...NHS England
Expo is the most significant annual health and social care event in the calendar, uniting more NHS and care leaders, commissioners, clinicians, voluntary sector partners, innovators and media than any other health and care event.
Expo 15 returned to Manchester and was hosted once again by NHS England. Around 5000 people a day from health and care, the voluntary sector, local government, and industry joined together at Manchester Central Convention Centre for two packed days of speakers, workshops, exhibitions and professional development.
This year, Expo was more relevant and engaging than ever before, happening within the first 100 days of the new Government, and almost 12 months after the publication of the NHS Five Year Forward View. It was also a great opportunity to check on and learn from the progress of Greater Manchester as the area prepares to take over a £6 billion devolved health and social care budget, pledging to integrate hospital, community, primary and social care and vastly improve health and well-being.
More information is available online: www.expo.nhs.uk
An industry-wide survey of the health ecosystem. By looking at leading operating models that are representative of the future health ecosystem, the viewer can get a handle on how the future will look.
GenSearch - Innovation in Healthcare: What is the Point?Alix Aubert
In this white paper, you will discover instances where innovation in technology and organisational operations are connecting patients to healthcare providers and are sharing secure clinical data with researchers. Others have disrupted traditional manufacturing methods to improve processes and some have even transformed organisational operations to create customer trust, value, and to improve outcomes for patients.
Top HR & Workplace Benefits Trends to Improve Employee Satisfaction + Family ...Aggregage
In this webinar, you will learn and understand how to offer flexible oral and vision benefits and convenient access to this type of care for children and families.
Khizar HayatPublic Health FoundationType two diabetesAssessmen.docxcroysierkathey
Khizar Hayat Public Health Foundation Type two diabetes
Assessment Coversheet and Feedback Form
Faculty of….
School of….
First Marker Name:
Aldo Mussi
First Marker Signature:
AM
Date:
Jan’20
Feedback: General comments on the quality of the work, its successes and where it could be improved
Hi Khizar - Thank you for submitting your work.
However, there are a number of things which must be strengthened to bring it up to Level 7 standard.
Right from the background, good, recent sources are often lacking, and your exploration of causes is far too brief (Indeed, you don’t even refer to a basic ‘energy in – energy out’ equation for T2D). Your selection of interventions appears arbitrary and poorly supported, with no real attempt to examine ‘Health-Evidence-People’. Crucially, for Level 7 work, some attempt at critical analysis is needed.
You could use your Beattie model to analyse the interventions, and your ethics discussion should apply a framework to those interventions. The policy discussion should examine a current government example.
A number of whole paragraphs are without a source, so you referencing needs serious attention.
Provisional Uncapped Mark Marks will be capped if this was a late submission or resit assessment and may be moderated up or down by the examination board.
37 %
Feed Forward: How to apply the feedback to future submissions
Please arrange a tutorial to debrief this feedback, and seek support from the Centre for Academic Success.
Table of Content
Contents
INTRODUCTION 4
BACKGROUND 4
PUBLIC HEALTH INTERVENTIONS OF TYPE 2 DIABETES 6
Beattie’s Model of Health Promotion 10
ETHICS 11
HISTORY AND POLICY FOR TYPE 2 DIABETES INTERVENTIONS 12
CONCLUSION 12
REFERENCES 13
Type two Diabetes and Public HealthINTRODUCTION
Type 2 Diabetes was chosen to be the topic of discussion in this assignment as it is a common type of diabetes, making it a public health issue. This occurs when the blood sugar level has surpassed the normal level, basically the blood sugar, comes from the food eaten and I is the main source of energy needed to run our bodies. Whereby hormones made by the pancreas and insulin aids the glucose to get into our body cells to provide the energy needed. The connection comes in whereby the glucose or blood sugar level is much more than needed which makes the insulin not to be enough or the insulin that is present is not used well. Basically, that is the general description of type two diabetes. Therefore, the result is that too much sugar remains in the blood and the cells lack enough to run the body on a daily basis. This type of diabetes mainly affects people of every age, it cannot be considered as a condition for only people. This type of diabetes affects at every age even age childhood. Comment by Aldo Mussi: Rethink this (with Refs).
But generally, it affects most people who are middle aged and older people, especially under predisposing aspects such as family history of diabetes and obesity. Based on demo ...
Today's companies must begin to look at employee health, not as a cost, but an investment. Data show conclusively that the health status of a company's employees is directly correlated to the profitibility and competitiveness of the company. This is not an American challenge, but a global challenge and responsibility. This was a keynote address to a dozen major US corporations in May, 2008. I'm happy to discuss with anyone of interest.
10 Most Trusted Diabetes Solution Providers in 2022.pdfinsightscare
In the following edition of Insights Care, “10 Most Trusted Diabetes Solution Providers in 2022,” we highlight ten such companies that have put forth their innovative foot.
10 Most Trusted Diabetes Solution Providers in 2022V3 2.pdfinsightscare
In the following edition of Insights Care, “10 Most Trusted Diabetes Solution Providers in 2022,” we highlight ten such companies that have put forth their innovative foot.
February 14, 2020
On February 14, 2020, Harvard Medical School Center for Bioethics and the Program on Regulation, Therapeutics, and Law (PORTAL) at Brigham and Women's Hospital, in collaboration with the Petrie-Flom Center hosted the monthly health policy consortium on sugar-sweetened beverage excise taxes.
In recent years, some cities have tried to impose soda taxes and other new policies to reduce the obesity epidemic in the US—particularly among children—and its critical impact on society and the health care system. How effective are these policies? What is blocking their uptake? What alternatives should we consider?
For more information visit our website at: https://petrieflom.law.harvard.edu/events/details/soda-taxes-and-other-policy-responses-to-the-american-obesity-epidemic
Similar to James Nakagawa, How technology made us healthier, GCF2012 presentation (20)
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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