Global Health Challenges such as Obesity, Diabetes, Pandemics and antibiotic-resistant viruses present a real and present danger, not just for the future of national health service provision, but also, arguably, for the future of mankind. This presentation, delivered at the Segamed 2015 conference in Nice in December 2015 focuses primarily on lifestyle related conditions such as obesity. The presentation makes the argument for a collaborative approach from all sectors of society and that the medical profession alone cannot be expected to provide solutions for problems which are essentially self-inflicted. The presentation looks at the combination of gamification and enabling technologies and, using the analogy of a car, suggests that the human body is our vehicle for taking us through life's journey. Using technology to monitor the condition of our body and developing tools which give us the equivalent of a human sat-nav for our life journey can help to shift responsibility and power for health management towards the citizen and the communities in which we exist.