The MIT Enterprise Forum of Cambridge gathered together a crowd on March 29, 2017 at the Broad Institute to hear about some of the most exciting wearable technologies on the front wave of transformation in healthcare. From devices that measure brain activity and track workouts, to systems that stimulate muscles to minimize workouts, to body sensors and voice-activated collaborative care solutions that help improve patient engagement and quality of care, the possibilities are near endless. Please note not all slides presented at the live event are available here, per the request of the presenting companies. For more information about the MIT Enterprise Forum of Cambridge and all of our programs, please visit: www.mitforumcanbridge.org

1. Connected Health: Emerging Tech Poised to Make Our
Lives Better
Welcome & Introductions
Katja Wald
Christina Licursi
Keynote
Joseph Kvedar, MD
Startup Presentations
Emerald
humon
MC10
MobioSense
Neumitra
Orbita
Sensico
Drinks + Networking
Broad Lobby
March 29, 2017
@mitefcmb | #InnoSeries

2. A Critical Look at
Connected Health
Adoption in 2017
Joseph Kvedar, MD
March 29, 2017

3. 3
1990
’s

4. 4
2000
’s

5. Connected Health is a
Vibrant Marketplace
Virtual visits
Remote monitoring
Wearables
Mobile
Apps/Engagement tools

6. Connected
Cardiac
Care

7. Diabetes
and Blood
Pressure
Demonstrated lowered
blood pressure
Demonstrated lower
HbA1c

8. Engagement
and
Diabetes
0.36
1.08
0.62
Lowengagement HighEngagement All
HbA1cChange

9. What is left to
do?
Time to
Retire?

10. Challenges That Remain
Provider Patient Payer

11. 1300 MDs Surveyed
80% 45% 12%
Have Worries
Liability
Privacy/security
EMR integration
Reimbursement
Are Enthusiastic Have adopted

12. Patient Barriers
Design and Usability
No UI/Frictionless
Use proven engagement
tools
Software with Empathy
Near term impact
Personalization
Social
Subliminal messaging
Unpredictable rewards
Sentinel effect

13. Insurers
ROI
Consumers change
plans
Risk contracts are
adjusted yearly
Pay today for savings
tomorrow?

14. Opportunities
Make it easy for MDs to
adopt
Focus on patient
usability
Explore new business
models

15. Thank You
Connect with me. The cHealth Blog:
chealthblog.connectedhealth.org
partners.org/connectedhealth
The Internet of Healthy Things:
Theinternetofhealthythings.com
LinkedIn Group:
Connected Health Community
Twitter:
@connectedhealth
@jkvedar
Contact Me:
jkvedar@partners.org

17. Emerald
In-Home Non-Contact Health Monitoring

18. Emerald Box
Wireless device that
monitors health metrics,
vital signs and activities
Emerald Cloud
Cloud based management
platform using the data of
Emerald Box to improve results
EMERALD

19. Wireless device that does NOT need to be worn and monitors:
EMERALD
Mobility Vital Signs
ADLs & Daily Pattern
Breathing
Heart RateGait Speed
No Patient Adherence Problems!
Falls

20. 1
• 1. Sleep
2
4
3
2. Home Patterns
3. Bathroom Usage
4. Withdrawal vs.
Interaction
QUALITY OF LIFE
QUANTIFIED

21. MobioSense
Justin Yang MD MPH
Chief Medical Officer

22. Every 43 seconds,
an American suffers a Heart attack.

23. We can’t Prevent
what
We can’t See
Tests we use now are:
• Not sensitive enough for prevention
• Expensive & requires reagent/ refrigeration

24. HERO
Instant & Affordable Heart Attack Monitoring with
1 Drop of Fingerstick Blood

25. 4th generation ultra-sensitive troponin
Portable, Real time results in 10 minutes
100X sensitive than current in-hospital tests
$4 MSRP: 70% markdown

26. Competitive Analysis
* Anticipated MSRPs

27. FDA 510 (k)
FDA
CLIA-w
Now
Tomorrow
Future- Telemedicine
2017
Validation
2019
Point-of-Care
2022
Home Care
Multi-marker heart panel
• HPV
• HIV
• Hepatitis
• Kidney injury
One
HERO
for
All
diseases

28. What does the future
look like with HERO?
What is the
Future?

31. STRATEGIC PARTNERS & MENTORS
CLINICAL PARTNERS & NATIONAL GRANTS
2016 FINALIST
2016 SEMI-FINALIST
2017 FINALIST
$160K
$25K $40K
WINNER
Interested in learning more about us?

32. 735,000
Americans suffer from heart attacks
every year

33. Future starts Now

34. Voice. First.
www.orbitavoice.com
www.orbitahealth.com
@orbitahealth

36. The Rise of Voice-First Experiences
2000
Websites •Bots
•Voice
•Faceless
Computing
”Bots are like new applications
that you can converse with.”
(Satya Nadella, Microsoft CEO)
20202010
Mobile
Apps

37. Connected Healthcare…
and the $300B* medication and treatment adherence problem
Care Journey
• Engage Patients
• Practical and intuitive user
experiences that empower and
motivate
• Empower Caregivers
• Collaboration and communication
for better support and advocacy
• Inform Clinicians
• Care journey management for
better awareness, data-driven
insights, and interventions
CLINICIAN
PATIENT
CAREGIVE
R

38. • Decisions
• Is 150 bad?
• Actions
• What action
should be taken?
• Engagement
• What do I send
back to the user?
My blood
pressure is 150
over 85
The Problem

39. Care Journey Management
for the Connected Patient
“I took my medicine .”
May 5, 2017 9:32A
Meds Taken
Coumadin 10 Mg
• Contextual Journey
Management
• Conversational UX Design
• Rules and AI-based
Decision Logic
“Got it. You took your Tuesday morning
Coumadin. Please remember to use your CPM
machine for 30 mins today.“

40. Example: Chronic Care Management
Increased patient
engagement and
treatment adherence
=
Reduce emergencies
and re-admissions
Population Care Dashboard
Analog
Digital
Start my therapy
session
…breath in for 2
seconds starting
now...

41. © 2016 ORBITA, INC. PROPRIETARY AND CONFIDENTIAL
Thank You!
Bill Rogers, CEO
bill@orbitahealth.com
603-801-5065

42. Experience Management
for Conversational Applications
CONSUMERS BUSINESSES
Orbita helps companies maximize business
value from next generation “Voice First”
applications
Google
Home
Amazon
Echo©
Bots Voice Assisted Vehicles

43. Orbita Engage™
• Complete care collaboration and patient journey management solution
Orbita Voice™
• Design, build, and maintain intelligent voice-powered health assistants
Orbita Cloud™
• Secure (HIPAA-compliant) cloud platform for smart, connected healthcare
applications
Our Products
Voice Experience Designer

44. For Business Analysts…
• Easily Create and
Manage Voice-First
User Experiences
• Track User
Engagement
• Perform A/B Testing
• Leverage Pre-built
Templates (Surveys,
Instructions,
Knowledge Bases,
Messaging,…) Voice Management
Portal

45. Orbita Engage
User Journey Management
Complete user journey
management optimized for
connected, conversational
experiences
• Engagement and Activity Management
• Domain-specific templates (Healthcare)
• Messaging and Communication
• Smart Content Curation and Delivery
• Flexible Device and System Integrations
• “Voice-First” UX Support (via Orbita
Voice)
• Data-driven Insights and Actions

46. Digital Therapeutics for In-Home Health
Management of Patients with Complex Chronic
Conditions
Howard Brick
Senior Advisor
howardb@sensciosystems.com
Senscio Systems

47. • Using digital innovations to transform health management of people with multiple chronic conditions
• Artificial intelligence provides real-time insights & actionable intelligence to enable:
- Earlier interventions
- Improved outcomes
- Lower costs
• Proven results, ready to scale commercially
2
Introduction

48. • 3+ chronic conditions and/or failure to
meet treatment goals
• 15+ chronic medicines and/or
multiple high risk medications
• High social service needs interfering
with care
• Hospital Admissions: 5+ in year
• ED Utilization: 5+ in year
3
Meet Pauline - a Typical
Ibis User

49. 4
Addressing Known Gaps
11%
17%
21%
32%
56%
63%
0% 25% 50% 75%
Inability to monitor patients between visits
High frequency of calls or visits from patients
Patients' hesitation toward price of tests and Rx
Patients' inconsistency in following treatment plans
The complexity of managing multiple conditions
Lack of time to provide the extra guidance and
reinforcement these patients require
According to a poll of 500 primary care physicians*, biggest challenges in
caring for patients with multiple chronic conditions are:
These are the unmet needs that our business addresses
* http://hitconsultant.net/2015/09/28/challenge-caring-chronic-care-patients/

50. • Support healthcare between
physician office visits
- Engage patients in their own
care
- Monitor adherence and
health
- Trigger timely interventions
• Augment physician’s ability to
adjust care
5
The Practical Solution

51. Introducing Ibis
6
Digital therapeutics platform
powered by unique artificial
intelligence
Timely, personalized, and
responsive coaching and care
coordination
+
99% of effort 1% of effort
Driving Outcomes through Intelligent Activation and Intelligent Intervention

54. 10
> 85%
average adherence to prescribed care plan,
versus 50% norm
> 90%
of exacerbations are detected and treated at
home, 3-7 days earlier than usual
> 20%
fewer hospitalization per patient per year; 70% for COPD population
$5000 cost savings potential per patient per year
100%
of patients feel more in command of health
Early results indicate high impact

55. 12
Creating an unbroken
process for optimal
care coordination