This document discusses various methods for separating mixtures into their pure constituents, including evaporation, centrifugation, separation using a separating funnel, sublimation, distillation, fractional distillation, chromatography, crystallization, and separation of air components. It provides examples of using these methods to purify salt water, separate dye colors, and extract iron. Physical changes that alter state but not chemical composition are also distinguished from chemical changes involving new substances. Pure substances are defined as elements or compounds, not mixtures.