This document summarizes a seminar on ion chromatography. It describes ion chromatography as a form of liquid chromatography that uses ion exchange resins to separate atomic or molecular ions based on their interaction with the resin. It was initially developed in the 1940s to separate rare earths and transuranic ions for nuclear weapons. The instrumentation can use a standard HPLC setup with arrangements to suppress mobile phase signals, including a solvent delivery system, sample injection system, separating column, stripping column, detector, and recorder. The document discusses suppressor-based and single column ion chromatography and their applications, which include separation and detection of trace anionic and cationic species, analysis of food and environmental samples, and analysis of polyvalent anions and

1. A SEMINAR ON
ION CHROMATOGRAPHY
Submitted by:-
Nidhi Maheshwari
M.Sc. (Applied
Chemistry)

3. Introduction
 Ion Chromatography (IC) is a form of Liquid
Chromatography that uses ion exchange
resins to separate atomic or molecular ions
based on their interaction with the resin.
 It was initially developed in early 1940s in
order to separate and concentrate rear earths
and transuranic ions for development of first
nuclear weapon.

4. Instrumentation and
Technique
 Can be performed on standard HPLC
instrument, with arrangements to
suppress mobile phase signals.
 Set up consist of:-
 Solvent delivery system
 Sample injection system
 Separating column
 Stripping column
 Detector
 Recorder

6.  Types of Ion
Chromatography
 Suppressor
based Ion
Chromatography
 Single column Ion
Chromatography

7.  Working and regeneration of
suppressor

8. Applications
Separation and detection of trace anionic and
cationic species.

9. Analysis of food products to check for
presence of ionic contaminants and also
guarantee its quality.
Environmental analysis
Biological applications
Analysis of polyvalent anions.
Analysis of multi element transition
metals.