This document discusses interoperability and RTI's experience with facilitating interoperability between complex distributed systems. It describes RTI's work on over 800 projects across various industries involving 15+ standards efforts. RTI promotes using data-centric middleware like DDS to allow systems built with different technologies, platforms and vendors to easily share information through a common data model and quality of service controls. The document argues this approach improves integration, flexibility and future-proofing for systems compared to traditional methods.