CLONAL SELECTION THEORY IS AN SCIENTIFIC THEORY IN IMMUNOLOGY THAT EXPALINS THE FUNCTION OF CELLS OF THE IMMUNE SYSTEM IN RESPONSE TO SPECIFIC ANTIGEN INVADING THE BODY.
The ppt covers the following topic-
1.Introduction about antibody.
2. Types of antibody.
3.Genetic basis of antibody diversity.
4. Antibody diversity.
5.Light chain gene segment.
6. Mechanism of variable region DNA rearrangment.
7. Heavy chain gene segment.
8.Alternate splicing.
CLONAL SELECTION THEORY IS AN SCIENTIFIC THEORY IN IMMUNOLOGY THAT EXPALINS THE FUNCTION OF CELLS OF THE IMMUNE SYSTEM IN RESPONSE TO SPECIFIC ANTIGEN INVADING THE BODY.
The ppt covers the following topic-
1.Introduction about antibody.
2. Types of antibody.
3.Genetic basis of antibody diversity.
4. Antibody diversity.
5.Light chain gene segment.
6. Mechanism of variable region DNA rearrangment.
7. Heavy chain gene segment.
8.Alternate splicing.
SOS response was discovered by Miroslav Radman. It's a part of DNA repair system- synthesizes enzymes required for DNA repair. Cellular response to UV damage.
One of the important parts in the study of Immunology.I prepared it for the sake of a seminar series competition conducted in my university. Now I thought of sharing it with others.
I took major content from this website i came across. https://www.thevirtualnotebook.com
it's legit since it's sources are books. My other references are mentioned in the last second clip.
SOS response was discovered by Miroslav Radman. It's a part of DNA repair system- synthesizes enzymes required for DNA repair. Cellular response to UV damage.
One of the important parts in the study of Immunology.I prepared it for the sake of a seminar series competition conducted in my university. Now I thought of sharing it with others.
I took major content from this website i came across. https://www.thevirtualnotebook.com
it's legit since it's sources are books. My other references are mentioned in the last second clip.
Immunoglobulins:
The Antibodies or Immunoglobulins are globular proteins present in the serum and tissue fluids. They are produced by the plasma cells (B-cells) and are used in the immune system of the body to neutralize pathogenic microbes or other toxic foreign components.
What is an Antibody?Immunoglobulins: Classes and Sub classesvarinder kumar
Forms
History
Immunoglobulins: Classes and Sub classes
Epitope
Antibodies structure
Antibody–antigen interactions
Function
Medical Applications
Regulations
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Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
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1. SHRI RAMSWAROOP MEMORIAL UNIVERSITY
PRESENTED BY:
HIMANSHU VERMA
B.Sc. (H) Biotechnology
4th Semester
202110902120006
SUBJECT- IMMUNOLOGY
TOPIC- ISOTYPES, ALLOTYPES & IDIOTYPES
PRESENTED TO:
DR. NIRAJ TIWARI
(ASSISTANT PROFESSOR)
2. Isotypes: Iso=Same
Each different heavy- chain constant region is referred to as an isotype, and the
isotype of the heavy chains of a given antibody molecule determines its class.
Minor differences in the amino acid sequences of groups of light and heavy chains
led to further sub- classification of these heavy chains into sub- isotypes and their
corresponding antibodies therefore into subclasses.
3. allotypes: allo=different
Heavy or light-chain genes occur in multiple allelic forms, and alternative allelic
forms of the same isotype and referred to as allotypes.
Generally, two antibodies with allotypic differences will vary in just a few residues of
one of the immunoglobulin chains, and these residues constitute the allotypic
determinants.
4. Idiotypes: Idio=own
Idiotypes are the unique antigenic determinants present on variable heavy chain and
variable light region of individual antibody molecules.
Idiotypes are antibodies that recognize different specific epitopes.
Location: Variable region of heavy chain and light chain.
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