The Human Brain Project (HBP) is a ten-year initiative aimed at advancing neuroscience through collaborative research infrastructure, with a focus on reverse engineering the human brain and developing related algorithms. The Blue Brain Project, an integral part of HBP, seeks to create a synthetic brain to understand brain function and assist in medical advancements. While the potential benefits of this technology include preserving human intelligence and enhancing memory, it raises ethical concerns such as dependency on technology and the risks associated with human cloning.

1. Fazla Rabbi Mashrur
Roll:1515020
DEPARTMENT OF BIOMEDICAL
ENGINEERING, KUET
BME 2101
Human Anatomy
Human Brain Project
And
Blue Brain Project

2. Contents
▪ What is Human Brain Project?
▪ Goals of Human Brain Project
▪ Introduction to Artificial Brain
▪ Human Brain and the Blue Brain
Project
▪ Founder of HBP and BBP
▪ What is Blue Brain Project?
▪ Blue Brain Project Objectives
▪ Brain Simulation
▪ Modeling
▪ Uploading Human Brain
▪ Research Work
▪ Hardware and Software
Requirements
▪ Advantages
▪ Disadvantages
▪ Applications
▪ Conclusion

3. What is Human Brain Project?
▪ The Human Brain Project (HBP) is a large ten-year scientific
research project that aims to build a collaborative ICT-based
scientific research infrastructure to allow researchers across the
globe to advance knowledge in the fields of neuroscience,
computing, and brain-related medicine
▪ Founder : Henry Markram
▪ Around 100 scientists from 13
different institutions around the
world is working on it
▪ The HBP is coordinated by the École Polytechnique Fédérale de
Lausanne and is largely funded by the European Union.The project
is based in Geneva, Switzerland.

4. Goals of Human Brain Project
● In 1st 10 years reverse
engineering of neocortical tissue
will be mainly focused on. Cell
densities, number of cell types,
morphologies of cells ,anatomy,
physiology,electro- physiology and
gene expression of neuron.
● In 2nd 10 years development of
algorithm and software
ecosystem will be mainly focused
on. Which can take spontaneous
data ,constrain it in a dense
digital reconstruction of the
neocortical tissue.

5. Introduction to Artificial Brain
 Human brain, the most
valuable creation of god.
The man is called intelligent
because of the brain.
 But we loss the knowledge
of a brain when the body is
destroyed after the death .
 Is it really possible to create
a artificial human brain?
 “YES", the IBM & EPFL is
now developing a virtual
brain known as the BLUE
BRAIN

6. Introduction to Artificial Brain
● IBM’s Blue Gene supercomputer allows a quantum leap in the
level of detail at which the brain can be modelled.
● It would be the worlds first virtual brain.
● In 2025, we will be able to scan ourselves into the computers.

7. Human Brain and the Blue Brain Project
● The central vision for the Human Brain Project (HBP) -
reconstructing and simulating the human brain - was
developed by Henry Markram, based on the research
strategy developed in the Blue Brain Project.
● In January 2013, after multiple rounds of peer review,
the project was funded with 1 billion euro over 10 years.
The project began operations in October of the same year.
The project currently includes 112 partners.

8. Founder of HBP and BBP

9. What is Blue Brain Project?
● The Blue Brain Project is an
attempt to create a synthetic
brain by reverse-engineering
the mammalian brain down
to the molecular level in order
to understand brain function
through detailed simulations.
● Simply modeling of
Mammalian Brain

10. Blue Brain Project Objectives
● The project will search for
insights into how human beings
think and remember.
● Scientists think that blue brain
could also help to cure the
Parkinson's disease.
● The brain circuitry is in a
complex state of flux, the brain
rewiring itself every moment of
its existence. If the scientists can
crack open the secret of how and
why the brain does it, the
knowledge could lead to new
breed of supercomputers.

11. Brain Simulation
Natural Brain
▪ Input
▪ By neurons
▪ By sensory cells
▪ Interpretation
▪ Memory
Virtual Brain
▪ Input
▪ ANN with silicon chip.
▪ Electric impulses
▪ Interpretation
▪ Memory

12. Brain Simulation
● Simulating human brain
by reverse engineering &
combining biological
studies to digital
technology using concept
of Artificial Neural
Network (ANN)

13. Modeling
● Neurons receive inputs from thousands of other neurons, and
has branches of highly complex dendritic trees and require
tens of thousands of compartments to accurately represent
them.
● Therefore a massive increase in computational power is
required to make this quantum leap — an increase that is
provided by IBM’s Blue Gene supercomputer.
● Using a Blue Gene supercomputer running Michael Hines's
NEURON software, the simulation does not consist simply of an
artificial neural network, but involves a biologically realistic
model of neurons.

14. Uploading Human Brain
▪ The uploading is possible by
the use of small robots
known as the NANOBOTS.
▪ These robots are small
enough to travel throughout
our circulatory system.
▪ Will monitor activity of brain
by traveling into the spine
and brain
▪ They will provide an interface
with computer .

15. Research Work
▪ IBM developing the “Blue brain” .
▪ IBM, in partnership with scientists at Switzerland’s Ecole
Polytechnique Federal De Lausanne’s(EPFL) Brain and Mind
Institute will begin simulating the brain’s biological systems.

16. Hardware and Software Requirements
● A Super computer.
● Memory with a very large storing capacity.
● Processor with a very high processing power.
● A very wide network.
● A program to convert the electric impulses from the brain
to input signal, which is to be received by the computer and
vice versa.
● Very powerful Nanobots to act as the interface between
the natural brain and the computer.

17. Advantages
Intelligence of a person is not lost even after his death
Things can be remembered easily without much effort
Allowing deaf to hear via nerve simulation
Making decisions without the presence of the person
in processing speed and memory could make entire
human brain simulated
The activity of different animals can be understood

18. Disadvantages
We become dependent upon the computer
Others may use technical knowledge against us
Another fear is found today with respect to human
cloning
A very costly procedure of regaining the memory
back

19. Applications
▪ gathering and testing 100 years of data
▪ cracking the neural code
▪ a foundation for molecular modeling of brain function
▪ understanding neocortical information processing
▪ a novel tool for drug discovery for brain disorders
▪ a global facility
▪ a foundation for whole brain simulations

20. Conclusion
▪ We will be able to transfer ourselves into
computers at some point.
▪ It will bring both benefits and harm to human
society .
▪ Very soon this technology will be highly accepted
whole over the world.

22. ANY QUERIES…..
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