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Chapter 18 Regulation of gene expression Groen: Brinker expression Rood:  Knirps Blauw: Delta, vein marker From: Cook et al. 2004, Dev Biol. 131, 2113-2124
Contents Chapter 18 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
2  Regulation of a metabolic pathway ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
2  Regulation of a metabolic pathway ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
3  The tryptophane or trp -operon ,[object Object],[object Object],[object Object],[object Object]
3  The tryptophane or trp -operon ,[object Object],[object Object],[object Object],[object Object]
3  The tryptophane or trp -operon ,[object Object],[object Object],[object Object],[object Object]
3  Function of the repressor and operator ,[object Object],[object Object]
Ways to control an operon ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Cooper: The cell, 2 nd  ed.
4  The  lac -operon without lactose ,[object Object],[object Object]
4   Lac  operon switched on ,[object Object],[object Object],[object Object]
5  Glucose is preferred
5  Glucose is preferred
5  Glucose is preferred ,[object Object],[object Object],[object Object],[object Object],[object Object]
Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
6  Several controls in  eukaryotic gene expression ,[object Object]
First way to control gene expression   7 Chromatin structure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
First way to control gene expression   7 Chromatin structure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
8  Birth of a eukaryotic transcript (in this case a precursor for mRNA)
8  Birth of a eukaryotic transcript (in this case a precursor for mRNA)
8  Birth of a eukaryotic transcript (in this case a precursor for mRNA)
8  Birth of a eukaryotic transcript (in this case a precursor for mRNA)
8  Birth of a eukaryotic transcript (in this case a precursor for mRNA)
8  Birth of a eukaryotic transcript (in this case a precursor for mRNA)
8  Birth of a eukaryotic transcript (in this case a precursor for mRNA)
8  Birth of a eukaryotic transcript (in this case a precursor for mRNA) ,[object Object],[object Object],[object Object],[object Object],[object Object],Thank you…
How does RNA polymerase find its start? ,[object Object],[object Object],[object Object],[object Object],[object Object]
9  Role of enhancers and transcription factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(
9  Role of enhancers and transcription factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(
9  Role of enhancers and transcription factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(

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  • 1. Chapter 18 Regulation of gene expression Groen: Brinker expression Rood: Knirps Blauw: Delta, vein marker From: Cook et al. 2004, Dev Biol. 131, 2113-2124
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  • 19. 8 Birth of a eukaryotic transcript (in this case a precursor for mRNA)
  • 20. 8 Birth of a eukaryotic transcript (in this case a precursor for mRNA)
  • 21. 8 Birth of a eukaryotic transcript (in this case a precursor for mRNA)
  • 22. 8 Birth of a eukaryotic transcript (in this case a precursor for mRNA)
  • 23. 8 Birth of a eukaryotic transcript (in this case a precursor for mRNA)
  • 24. 8 Birth of a eukaryotic transcript (in this case a precursor for mRNA)
  • 25. 8 Birth of a eukaryotic transcript (in this case a precursor for mRNA)
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