Home DNA testing: How do genes determine a person’s reaction to drugs, nutrients and vitamins? How can you test your genes for your biological age? Find out more!
Role of genetics in periodontal diseasesAnushri Gupta
Terminologies in Genetics
Genetic study design
genetic syndrome and disease associated with periodontal diseases, heretibility of periodontal disease, gene library, gene therapy
The study of how genes and gene products interact with dietary chemicals to alter phenotype and, conversely, how genes and their products metabolize nutrients is called nutritional genomics or “Nutrigenomics”.
Nutrigenomics is the science that examines the response of individuals to food compounds using post-genomic and related technologies (e.g. genomics, transcriptomics, proteomics, metabol/nomic etc.). The long-term aim of nutrigenomics is to understand how the whole body responds to real foods using an integrated approach termed 'systems biology'. The huge advantage in this approach is that the studies can examine people (i.e. populations, sub-populations - based on genes or disease - and individuals), food, life-stage and life-style without preconceived ideas.
Contents- Introduction to Immunodeficiency | Types | SCID | LAD
Immunodeficiency is the inability to produce an adequate immune response because of insufficiency or absence of antibodies, immune cells or both.
SCID & LAD are the two immunodeficiencies from primary immunodeficiency.
Gene therapy is the process of inserting therapeutic genes into cells to prevent or cure wide range of diseases. The newly introduced genes will encode proteins and correct the deficiencies that occur in genetic diseases. Gene therapy primarily involves genetic manipulations in animals or humans to correct a disease, and keep organism in good health. It is a technique for correcting defective genes responsible for disease and development.
Role of genetics in periodontal diseasesAnushri Gupta
Terminologies in Genetics
Genetic study design
genetic syndrome and disease associated with periodontal diseases, heretibility of periodontal disease, gene library, gene therapy
The study of how genes and gene products interact with dietary chemicals to alter phenotype and, conversely, how genes and their products metabolize nutrients is called nutritional genomics or “Nutrigenomics”.
Nutrigenomics is the science that examines the response of individuals to food compounds using post-genomic and related technologies (e.g. genomics, transcriptomics, proteomics, metabol/nomic etc.). The long-term aim of nutrigenomics is to understand how the whole body responds to real foods using an integrated approach termed 'systems biology'. The huge advantage in this approach is that the studies can examine people (i.e. populations, sub-populations - based on genes or disease - and individuals), food, life-stage and life-style without preconceived ideas.
Contents- Introduction to Immunodeficiency | Types | SCID | LAD
Immunodeficiency is the inability to produce an adequate immune response because of insufficiency or absence of antibodies, immune cells or both.
SCID & LAD are the two immunodeficiencies from primary immunodeficiency.
Gene therapy is the process of inserting therapeutic genes into cells to prevent or cure wide range of diseases. The newly introduced genes will encode proteins and correct the deficiencies that occur in genetic diseases. Gene therapy primarily involves genetic manipulations in animals or humans to correct a disease, and keep organism in good health. It is a technique for correcting defective genes responsible for disease and development.
Genetic and epigenetic biomarkers for therapeutic monitoring in neurological ...Pranav Sopory
Seminar held on Genetic and epigenetic biomarkers for therapeutic monitoring in neurological disorders.
Multiple Sclerosis, Alzheimer's Disease and Parkinson's Disease.
Biomarkers and epigenetic explained. New epigenetic drug targets.
Richard Frye, MD, PhD, FAAP, FAAN, CPI, will discuss:
*The enteric (gut) microbiome has an important influence on health and disease states in humans.
* The enteric microbiome influences the human host using chemical mediators, some of which can directly affect mitochondrial function
* Short chain fatty acids produced by gut bacteria not only modulate mitochondrial function and cellular regulatory pathways, but can also be used as mitochondrial fuels.
A healthy immune system defends the body against disease and infection. But if the immune system malfunctions, it mistakenly attacks healthy cells, tissues, and organs. Called autoimmune disease, these attacks can affect any part of the body, weakening bodily function and even turning life-threatening.
Gene Therapy: Central concept of gene therapy, basic molecular mechanism of gene transfer, prerequisite of human gene therapy, biological basis of gene therapy strategies, vehicles for gene transfer, Antisence oligonucleotides and RNAi, clinical gene therapy studies, gene therapy for hereditary disease, gene therapy for cancer, gene therapy for HIV.
Uso ed abuso dei farmaci - Applicazione delle informazioni genetiche per un u...Digital for Academy
Il seminario dello scorso 17 Aprile 2015 ha affrontato i temi dell’aderenza alla terapia e dell’appropriatezza prescrittiva toccando, tra le varie specialità aziendali, l’antibiotico terapia, i vaccini, la farmacogenetica e il suo uso nelle cure psichiatriche. Sono state inoltre analizzate delle possibili strategie digitali che consentano a medici, farmacisti e aziende di scegliere la cura più adatta per una determinata patologia e che agevolino il paziente nel seguirla al meglio.
Presentazione del dott. Marco Marchetti, CEO - FB Health.
the new emerging field of science that is nutrigenomics can deal with the issues of health and improve out health with the simple tools by understanding the risk and the baic genome of a person
Prof. Dr. Vladimir Trajkovski - Epigenetics of ASD-10.05.2019Vladimir Trajkovski
President of MSSA Prof. Dr. Vladimir Trajkovski presented this topic "Epigenetics of Autism Spectrum Disorders" at the mini simposyum in Voerandaal, Holland, organized by ReAttach Academy at May 10th 2019.
It will be an appropriate source for you to understand about the food toxicology. Further, the impacts of genetically modified are discussed in detail. the effects of toxicity in human and other living organisms are included in this document with examples.
Genetic and epigenetic biomarkers for therapeutic monitoring in neurological ...Pranav Sopory
Seminar held on Genetic and epigenetic biomarkers for therapeutic monitoring in neurological disorders.
Multiple Sclerosis, Alzheimer's Disease and Parkinson's Disease.
Biomarkers and epigenetic explained. New epigenetic drug targets.
Richard Frye, MD, PhD, FAAP, FAAN, CPI, will discuss:
*The enteric (gut) microbiome has an important influence on health and disease states in humans.
* The enteric microbiome influences the human host using chemical mediators, some of which can directly affect mitochondrial function
* Short chain fatty acids produced by gut bacteria not only modulate mitochondrial function and cellular regulatory pathways, but can also be used as mitochondrial fuels.
A healthy immune system defends the body against disease and infection. But if the immune system malfunctions, it mistakenly attacks healthy cells, tissues, and organs. Called autoimmune disease, these attacks can affect any part of the body, weakening bodily function and even turning life-threatening.
Gene Therapy: Central concept of gene therapy, basic molecular mechanism of gene transfer, prerequisite of human gene therapy, biological basis of gene therapy strategies, vehicles for gene transfer, Antisence oligonucleotides and RNAi, clinical gene therapy studies, gene therapy for hereditary disease, gene therapy for cancer, gene therapy for HIV.
Uso ed abuso dei farmaci - Applicazione delle informazioni genetiche per un u...Digital for Academy
Il seminario dello scorso 17 Aprile 2015 ha affrontato i temi dell’aderenza alla terapia e dell’appropriatezza prescrittiva toccando, tra le varie specialità aziendali, l’antibiotico terapia, i vaccini, la farmacogenetica e il suo uso nelle cure psichiatriche. Sono state inoltre analizzate delle possibili strategie digitali che consentano a medici, farmacisti e aziende di scegliere la cura più adatta per una determinata patologia e che agevolino il paziente nel seguirla al meglio.
Presentazione del dott. Marco Marchetti, CEO - FB Health.
the new emerging field of science that is nutrigenomics can deal with the issues of health and improve out health with the simple tools by understanding the risk and the baic genome of a person
Prof. Dr. Vladimir Trajkovski - Epigenetics of ASD-10.05.2019Vladimir Trajkovski
President of MSSA Prof. Dr. Vladimir Trajkovski presented this topic "Epigenetics of Autism Spectrum Disorders" at the mini simposyum in Voerandaal, Holland, organized by ReAttach Academy at May 10th 2019.
It will be an appropriate source for you to understand about the food toxicology. Further, the impacts of genetically modified are discussed in detail. the effects of toxicity in human and other living organisms are included in this document with examples.
It is about aging and how aging is tried to controlled by different sort of methods and animals models are used in the testing the products created by science. It explains the different theories of aging in a very detailed manner. And the very least includes different animal models like mouse and monkey on which these treatments are applied and checked the effects of them that how we can control aging. We, can never say that controlling aging is something about that we are becoming immortal it is totally about finding the factors which can reduce tha aging and aging related diseases.
substances released by one microorganism, stimulating the growth of another microorganism.”Live microbial supplements which beneficially affects the host animal by improving it’s microbial balance.”
What is personalized medicine?
Why we need personalized medicine?
What’s Pharmacogenetics?
DNA polymorphism
Biomarkers
Today’s treatments with PM
Future insights
Challenges
What we still need to know more
Epigenetics definition, history of epigenetics, molecular basis of epigenetics, epigenetic modification, tools to study epigenetics, disease linked with epigenetics, DNA methylation demethylation and enzymes regulating DNA methylation
How and Why Pesticides Affect Our Healthmomasunite
Dr. Myrto Ashe, MD, MPH presents scientific evidence that pesticides affect the health of our children. She explains the mechanism of how pesticides disrupt the health of children.
The leaflet aims at providing general objective information on genetic tests, including their nature and the potential implications of their results. It presents the different types of tests available, their applications in the medical field and the extent and limit of the significance of the information resulting from these tests.
More information - www.coe.int/bioethics
Read about the 9 funny winning achievements of the Ig Nobel Prize 2021 in life science categories. From biology, ecology and chemistry to peace, economy and more.
The funny side of science: The Ig Nobel Prize honours achievements that make people laugh but also think afterwards! Here are the 8 best Ig Nobel Pize winning achievements.
While shopping meat, consumers ask: "What is the origin of the meat I buy and what were the rearing conditions of the animals? Is the meat hormone- and antibiotics-free? Is it organic and from grass-fed and free-range raised animals?"
How can meat processors and retailers assure their customers that the meat they buy is actually the one declared on the packaging? Genomic Meat Sourcing enables full traceability of meat from the point of purchase to the farm of origin, transparency of the supply chain, and analytical verification of the meat.
Investigate archaea with the Eurofins Genomics Microbiome Profiling 3.0 service! In addition to profiling bacteria and fungi, we now offer profiling of the archaea community in your samples. Why did we include archaea? It has been found that archaea are associated with conditions such as irritable bowel disease, obesity, anorexia nervosa, but also with infectious diseases like brain abscesses. Methanogenic archaea in the digestive tract of ruminants are the main producers of the greenhouse gas methane. Archaea also play roles in the microbiomes of the human skin and mouth, they show growth- and health-promoting effects on plants, and are present in the microbiome of corals, intracellular niches in amoebae, protozoa, and termites. The option to profile archaea provides a tool for researchers to broaden the knowledge about the effects and impact of archaea.
A funny take on the biochemical and molecular biological regulation of the Christmas feeling.
Christmas season, the long anticipated and very special time of the year. It is widely known that this time is connected to temporal changes in human emotions and behaviour. Read here about the biochemical and molecular biological mechanisms that underlie these changes.
Inforgraphic describing where blood-based liquid biopsies can be used during cancer management. A brief summary of the characteristics of GATCLIQUID, GATC Biotech's liquid biopsy assays is also included.
An overview of circulating cell-free DNA (cfDNA) as liquid biopsy biomarkers and the role of circulating tumour DNA (ctDNA) in advancing cancer research and diagnosis through non-invasive tumour mutation profiling
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills MN
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
hematic appreciation test is a psychological assessment tool used to measure an individual's appreciation and understanding of specific themes or topics. This test helps to evaluate an individual's ability to connect different ideas and concepts within a given theme, as well as their overall comprehension and interpretation skills. The results of the test can provide valuable insights into an individual's cognitive abilities, creativity, and critical thinking skills
ISI 2024: Application Form (Extended), Exam Date (Out), EligibilitySciAstra
The Indian Statistical Institute (ISI) has extended its application deadline for 2024 admissions to April 2. Known for its excellence in statistics and related fields, ISI offers a range of programs from Bachelor's to Junior Research Fellowships. The admission test is scheduled for May 12, 2024. Eligibility varies by program, generally requiring a background in Mathematics and English for undergraduate courses and specific degrees for postgraduate and research positions. Application fees are ₹1500 for male general category applicants and ₹1000 for females. Applications are open to Indian and OCI candidates.
Salas, V. (2024) "John of St. Thomas (Poinsot) on the Science of Sacred Theol...Studia Poinsotiana
I Introduction
II Subalternation and Theology
III Theology and Dogmatic Declarations
IV The Mixed Principles of Theology
V Virtual Revelation: The Unity of Theology
VI Theology as a Natural Science
VII Theology’s Certitude
VIII Conclusion
Notes
Bibliography
All the contents are fully attributable to the author, Doctor Victor Salas. Should you wish to get this text republished, get in touch with the author or the editorial committee of the Studia Poinsotiana. Insofar as possible, we will be happy to broker your contact.
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
1. Home Genomics Testing
Know Thyself
Can you test your genes for your reaction to
drugs, nutrients and vitamins?
2. 2
Home genomics testing
Eurofins Genomics – The DNA Universe
“Know Thyself” is the English translation
of the Ancient Greek inscription at the
Temple of Apollo of Delphi “Gnōthi
Seauton”
How can the “knowledge” of DNA be
used for one’s benefit?
3. 3
The basis of human variations…
Eurofins Genomics – The DNA Universe
… is genetics
Variations between individuals
manifest on a spectrum, e.g:
• Savantism
• Rare disease
• Abnormal responses to therapeutic
agents
• Personality traits
• Rate of aging
Advancements in DNA
sequencing methods enable
precise information about:
• Ancestry
• Predisposition to disease
• Personality
• Dietary requirements
• And more
Home genomics testing enables everybody to
gain knowledge about one‘s individual variations!
4. 4
The concept behind home genomics testing kits is simple
Eurofins Genomics – The DNA Universe
Procedure
1. The home genomics testing kit is delivered via mail
2. Simple instructions for sample collection:
• Often, enclosed swab is used to scrub cells from inside of cheek Swab is placed in enclosed tube
• Saliva is collected in tube
3. Sealed package with sample is returned via mail
4. After sample arrival in lab, the DNA is extracted and analysed (via microarrays or next-generation sequencing (NGS))
5. Generated data is analysed by BioIT team
6. Results are provided online
5. 5
Home genomics testing for personality traits
Eurofins Genomics – The DNA Universe
Variations in personality traits have been linked to
genetic polymorphisms!
• Strong correlation between variations in genes encoding proteins
responsible for dopamine metabolism and personality traits ‘Openness to
experience’
• Higher levels of dopamine in prefrontal cortex (PFC) are associated with
higher engagement in cognitive and behavioural exploration and curiosity
• Enzyme Catechol-O-Methyltransferase (COMT) metabolises dopamine
in PFC
• Certain SNP in COMT (gene) called ‘Val158 Met’ leads to less efficient
version of the COMT enzyme
• Results:
• Decreased dopamine breakdown rate & higher dopamine levels in PFC
• Translates into higher scores in personality trait ‘Opennes’
SNP = single nucleotide polymorphism
Personality traits ‘Openness to experience’ defined as
general inclination to indulge in imaginative, artistic and
intellectual endeavours; represents intellect and creativity
6. 6
Eurofins Genomics - The DNA Universe
A person’s chronological age is not necessarily the person’s biological age
Chronological age
Represents number of years of life
Biological age
In a sense, relates to morbidity &
mortality risk, as well as aging
Epigenetic clock
Is based on methylation status of
DNA
It has been described as the most
accurate molecular measure of
age
Home genomics testing for the epigenetic clock – how old are you really?
Common practice
A person’s biological age is estimated
via certain clinical biomarkers
Shortcoming
Measuring biomarkers can be
somewhat misleading
“Hispanic mortality paradox”:
• People of Hispanic ancestry have,
in general, higher clinical risk
profiles but live longer than people
with European ancestry
• However, according to epigenetic
clock, Hispanics seem to age slower
Epigenetic clock (and rate of aging)
highly depends on genetic make-up
& seems to be hereditary
Example:
A person’s ancestors lived to be 100
years old or more
Probability that this person’s
epigenetic clock is “younger” than
somebody’s clock whose ancestors
did not live to be 100 years old is
very likely
7. 7
Home genomics testing for the epigenetic clock – how old are you really?
Eurofins Genomics – The DNA Universe
Benefit of analysing DNA methylation of an individual
• Prediction of biological age compared to chronological age
• If “DNA methylation age” is higher than chronological age, the risk for
certain diseases is often higher (positive age acceleration)
• If “DNA methylation age” is lower, it implies lower risk (negative age
acceleration)
• Statistically prediction of lifespan and onset of diseases, such as
coronary heart disease, cognitive decline or cancer based on DNA in
blood samples
• Statistical effect of diet and lifestyle factors on biological age (DNA
methylation GrimAge)
Eating vegetables and fruits (especially carotenoids), exercising &
even education have beneficial effects on aging
Smoking has most significant negative effect on aging followed by
inflammation, poor waist to hip ratio and diabetes.
8. 8
Home genomics testing for drug metabolism
Impact of SNPs on drug metabolism
• CYP2D6 encodes for enzyme Cytochrome P450 2D6
responsible for metabolism of nearly 25% of drugs on
the market
Example: Some beta-blockers used for different health
conditions such as high blood pressure
• SNPs in CYP2D6 account for varying enzyme activity
and different phenotypes
Eurofins Genomics - The DNA Universe
Poor drug metabolisers
Little or no CYP2D6 activity
Intermediate drug metabolisers
Intermediate CYP2D6 activity between poor and
normal metabolisers
Extensive drug metabolisers
Normal CYP2D6 activity
Ultrarapid drug metabolisers
Higher CYP2D6 activity that occurs as result of
expression of multiple copies of CYP2D6 gene
Knowing which class of metabolisers a person
belongs to and accordingly adjusting drug dose is
of great importance to achieve optimum therapeutic
effect & avoid unwanted side effects
9. 9
Vit D3 metabolism
• SNPs in CYP2R1 and CYP24A1 can predict
if a person is likely to be deficient in vit D3
• Vitamin D goes through two hydroxylation
reactions to be converted into active vit D3
Home genomics testing for nutrient and vitamin metabolism
Individual metabolism of vitamins
and nutrients varies drastically
according to individual’s genetic
make-up.
Eurofins Genomics – The DNA Universe
Vit D3 biosynthesis
• First hydroxylation step is catalysed by enzyme CYP2R1
SNPs in CYP2R1 have been associated with lower vit D3 serum levels
• CYP24A1 encodes for monooxygenase responsible for degrading active vit D3
Four SNPs in this gene have been linked to lower concentrations of vit D3
Identifying personal metabolism activity of vitamins and nutrients could support measures for improved physical
and mental performance
10. 10
Home genomics testing of the microbiome
Eurofins Genomics – The DNA Universe
The gut microbiome has profound effects on human health and well-being
Gut microbes are classified as commensal/mutualistic, beneficial,
pathogenic
• Beneficial microbes are involved in vitamin biosynthesis,
dietary fibre breakdown, butyrate & neurotransmitter production
• Commensal/mutualistic microbes do not harm the body
but are involved in defence against pathogens
• Pathogenic microbes cause harm to the body
Importance of well-balanced microbial community in the gut
Dysbiosis is imbalance of gut microbiome & is linked to
pathogenesis of illnesses such as inflammatory bowel
disease & diabetes
11. 11
Home genomics testing of the microbiome
Eurofins Genomics – The DNA Universe
Ingestion of beneficial microbes can have significant effects
on health
• Daily ingestion of probiotic containing 2 x 1010 CFU
Lactobacillus plantarum P8 reduced levels of stress &
enhanced cognitive abilities and memory
• Daily ingestion of probiotic containing 109 CFU Lactobacillus
plantarum DR7 showed same effects & lowered plasma
cortisol levels
Gut microbiome home testing kits enable analysis to determine if balanced and diverse gut microbiota that supports
optimal body and mind function is present
Analysis results can be used for dietary adjustments and ingestion of probiotics to improve gut flora
12. 12
Ig Nobel Prize 2021 winner for Physics & Kinetics
Eurofins Genomics – The DNA Universe
Further reading
Read more about the influence of the microbiome on human health at:
https://the-dna-universe.com/2018/03/08/the-influence-of-the-microbiome-on-human-health/
Did you know that the microbiome profoundly affects cancer and cancer development? Read more at:
https://the-dna-universe.com/2021/05/27/the-microbiome-of-cancer/
Metagenome analysis – Beyond microbiome analysis. Find out more at:
https://the-dna-universe.com/2019/05/29/microbiome-analysis-are-you-aware-of-all-the-applications/
How are faecal transplants used for the treatment of antibiotics-associated disease? Read more at:
https://the-dna-universe.com/2019/06/27/world-microbiome-day-2019-in-the-matter-of-faecal-transplants-
for-a-healthy-microbiome/
Overview of all microbiome-related articles at: https://the-dna-universe.com/category/microbiome-articles/
13. 13
Follow Us
Eurofins Genomics – The DNA Universe
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Funny content and interesting news
facebook.com/EurofinsGenomics/
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linkedin.com/company/eurofinsgenomics/
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Dedicated to DNA and Genomics
https://the-dna-universe.com/
14. 14
Eurofins Genomics whole product portfolio is structured to address 3 types of customer needs
Eurofins Genomics - The DNA Universe
BUILT
FOR YOU
Pre-designed and validated
packages for standard
applications
BUILD
YOUR OWN
Flexible standardized
modules for easy design
of custom solutions
CUSTOMISED
SOLUTIONS
Tailored solutions for
complex projects, designed
together with our experts
DNA & RNA
Oligonucleotides
Application oligos and
qPCR probes
Flexible modules to design
custom DNA and RNA oligos
e.g., custom qPCR assay
with primers and probe in
plates
Custom DNA
Sequencing
Simple premixed solutions in
tubes and plates
Flexible options for
sequencing in tubes and
plates
e.g., SNP analysis, primer
walking, GLP sequencing
Next Generation
Sequencing
INVIEW packages for
frequent applications
Flexible modules for DNA,
RNA and amplicon
sequencing
e.g., GLP sequencing,
custom amplicon panel
Gene Synthesis /
Molecular Biology
Synthetic genes and
site-directed mutagenesis
Modules of gene synthesis
for individual ordering (e.g.,
gene fragments)
e.g., super express gene
synthesis, plasmid
linearization
Genotyping &
Gene Expression
CLA for standard cell lines
and mycoplasma check
CLA for custom cell lines and
FLA
e.g., microarray analysis,
authenticity testing
Customer Care:
+49 7531 8160 68
support-eu@eurofins.com
eurofinsgenomics.com
15. 15
References
• Belsky, D. W., Caspi, A., Houts, R., Cohen, H. J., Corcoran, D. L., Danese, A., Harrington, H., Israel, S., Levine, M. E., Schaefer, J. D., Sugden, K., Williams, B., Yashin, A. I., Poulton, R., & Moffitt, T. E. (2015)
Quantification of biological aging in young adults. PNAS, 112(30): E4104-10.
• DNA Solutions (2021) Paternity Testing. [online] Available from: https://dnasolutions.com.au/product-category/dna-tests/paternity-test/ [accessed 19/10/2021].
• Deyoung, C. G., Cicchetti, D., Rogosch, F. A., Gray, J. R., Eastman, M., & Grigorenko, E. L. (2011) Sources of Cognitive Exploration: Genetic Variation in the Prefrontal Dopamine System Predicts
Openness/Intellect. Journal of research in personality, 45(4): 364–71.
• Chong, H. X., Yusoff, N., Hor, Y. Y., Lew, L. C., Jaafar, M. H., Choi, S. B., Yusoff, M., Wahid, N., Abdullah, M., Zakaria, N., Ong, K. L., Park, Y. H., & Liong, M. T. (2019) Lactobacillus plantarum DR7 alleviates stress
and anxiety in adults: a randomised, double-blind, placebo-controlled study. Beneficial microbes, 10(4): 355–73.
• Farahmand, N., Ouoba, L.I.I., Naghizadeh Raeisi, S., Sutherland, J., Ghoddusi, H.B. (2021) Probiotic Lactobacilli in Fermented Dairy Products: Selective Detection, Enumeration and Identification Scheme.
Microorganisms 9: 1600.
• Flockhart D.A., Thacker, D., McDonald, C., Desta, Z. (2021) The Flockhart Cytochrome P450 Drug-Drug Interaction Table. [online] Division of Clinical Pharmacology, Indiana University School of Medicine (Updated
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