The document provides information about AIDS/HIV in 3 paragraphs: 1) It defines AIDS as acquired immune deficiency syndrome caused by the HIV virus. It affects immune cells called CD4+ T cells. HIV was first reported in 1981 in the US. 2) Pediatric AIDS contributes to 15-20% of cases in developing countries. HIV can be transmitted from mother to child during pregnancy, delivery, or breastfeeding. By 2007, over 2 million children lived with HIV. 3) HIV attacks and destroys CD4+ T cells, weakening the immune system. If untreated, HIV progresses to AIDS. Common opportunistic infections in children with AIDS include Pneumocystis pneumonia and MAC (Mycobacterium

27. Immunological Categories CD4 + Lymphocyte count Clinical categories No sign / symptom (N) Mild sign/ symptom (A) Moderate sign/ symptom (B) Severe sign/ symptom (C) No evidence of suppression Normal >25% N1 A1 B1 C1 Evidence of moderate suppression Moderate reduction (15-24%) N2 A2 B2 C2 Severe suppression Severe reduction (<15%) N3 A3 B3 C3

31. Immunological Categories Age of child Cells/micro liter <12 month 1-5 years 6-12 years No evidence of suppression >1500 >1000 >500 Evidence of moderate suppression 750-1499 500-999 200-499 Severe suppression <750 <500 <200

36. Viral infection

49. Drugs Pediatric Dosage Nucleoside Reverse transcriptase inhibitor Zidovudine ZDV,AZT 90-180 mg/kg6-8hrly Didanosine ddI 90-150 mg/kg12hrly Lamivudine 3TC 4 mg/kg BD Stavudine d4T 1 mg/kg BD Abacavir ABC 8 mg/kg BD Zalcitabine ddc .005-.01 mg/kg 8hrly Non Nucleoside Reverse transcriptase inhibitor Nevi rapine NVP 120-200 mg/kg12 hrly Efavirenz EFV 200-600mg/kg6hrly Delaviridin DLV 400mg TDS

50. Rifonavir RTV 400-450 mg/kg 12hrly Nefinavir NFV 30mg/kg 8hrly Amprenavir 20mg/kg QID

61. S No Disease Described symptom Srotas References 1 Abhinayas jawar Hattojas Ras vaha S u 39/43-45 2 Pandu Ojagunakshaya Ras vaha C c 16/4 3 Raj yakshma Kinchit oja kalapatae Ras vaha C c 8/41 4 Sosha Sosha Ras vaha S u 41 5 Premha Ojakshaya Medo vaha C n 4/37 6 Unmad Oja sanjhyetae Mano vaha C n 7/11 7 Madatya ojanaas Mano vaha C c 24/79 8 Avarita vaat Vaat vaha C c 28/208

66. Oja Kshaya Visaransa Vyapada Kshaya

71. THANKS