Congestive heart failure (CHF) is a chronic progressive condition that affects the pumping power of your heart muscles. While often referred to simply as “heart failure,” CHF specifically refers to the stage in which fluid builds up around the heart and causes it to pump inefficiently. You have four heart chambers.
Heart failure (HF), often used to mean chronic heart failure (CHF), occurs when the heart is unable to pump sufficiently to maintain blood flow to meet the needs of the body.
A Global Problem
HIGHLY LETHAL 5 yr Survival rate “50%”
More M.I. cases now survive More Incidence of CHF due to damaged myocardium
Better options than before now available to treat CHF
Congestive heart failure (CHF) is a chronic progressive condition that affects the pumping power of your heart muscles. While often referred to simply as “heart failure,” CHF specifically refers to the stage in which fluid builds up around the heart and causes it to pump inefficiently. You have four heart chambers.
Heart failure (HF), often used to mean chronic heart failure (CHF), occurs when the heart is unable to pump sufficiently to maintain blood flow to meet the needs of the body.
A Global Problem
HIGHLY LETHAL 5 yr Survival rate “50%”
More M.I. cases now survive More Incidence of CHF due to damaged myocardium
Better options than before now available to treat CHF
Transplantation basics explained with history . For details look at the subtext for every slide. Immune suppression drugs. Body reaction to grafts are all explained
Definition of heart
The heart is a roughly cone-shape hollow muscular organ situated in the middle mediastinum of the thoracic cavity that's pumps blood to the body.
Definition of heart disease
A type of disease that affects the heart or blood vessels. The risk of certain heart diseases may be increased by smoking, high blood pressure, high cholesterol, unhealthy diet, lack of exercise, and obesity.
In pregnancy:
Maternal heart disease includes heart defects that are present at birth and acquired heart disease later in life. These can range from simple to complex. Examples include: A hole in the wall between the two sides of the heart. A heart valve that is too narrow or one that doesn't open or close properly.
Signs:
Chest pain, chest tightness, chest pressure and chest discomfort (angina)
Shortness of breath.
Pain, numbness, weakness or coldness in your legs or arms if the blood vessels in those parts of your body are narrowed.
Pain in the neck, jaw, throat, upper abdomen or back.
It is a presentation on Heart Disease in Pregnancy 2023
Welcome to our discussion on the fascinating topic of the difference between cardiac arrest and a heart attack.
While these terms are often used interchangeably, they actually refer to distinct medical emergencies with varying causes, symptoms, and treatments.
Understanding these differences is crucial as it can save lives and provide clarity in medical situations.
So, let's dive into this essential knowledge and shed light on the disparities between cardiac arrest and a heart attack.
Heart disease is a broad term for a range of conditions that affect the heart. It is the leading cause of death for both men and women in the United States.
CHAPTER 12: Cardiovascular Disease, Diabetes, and
Cancer
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood
vessels. Cardiovascular disease includes coronary artery diseases (CAD) such
as angina and myocardial infarction (commonly known as a heart attack). Other
CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart
disease, cardiomyopathy, heart arrhythmia, congenital heart disease, valvular heart
disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic
disease, and venous thrombosis.
The underlying mechanisms vary depending on the disease. Coronary artery
disease, stroke, and peripheral artery disease involve atherosclerosis, which is the
narrowing of the inside of an artery due to the build up of plaque. This may be
caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high
blood cholesterol, poor diet, and excessive alcohol consumption, among others. High
blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes
6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow
untreated strep throat. It is estimated that 90% of CVD is preventable.
Coronary heart disease (CHD), also commonly referred to as just heart disease, is a
common term for the buildup of plaque in the heart’s arteries that could lead to
heart attack. But is there a difference between coronary heart disease and coronary
artery disease? The short answer is often no — health professionals frequently use
the terms interchangeably. However, coronary heart disease, or CHD, is actually a
result of coronary artery disease, or CAD. With coronary artery disease, plaque first
grows within the walls of the coronary arteries until the blood flow to the heart’s
muscle is limited. View an illustration of coronary arteries below:
Coronary Arteries
The Coronary Arteries are the blood vessels that supply blood to your heart. They
branch off of the aorta at its base. The right coronary artery, the left main coronary, the
left anterior descending, and the left circumflex artery, are the four major coronary
arteries. Blockage of these arteries is a common cause of angina, heart disease, heart
attacks and heart failure.
This restriction of the blood supply to the tissues is also called ischemia. It may be
chronic, narrowing of the coronary artery over time and limiting of the blood supply
to part of the muscle. Or it can be acute, resulting from a sudden rupture of a plaque
and formation of a thrombus or blood clot.
Anatomy of the Cardiovascular System
To fully understand Cardiovascular Diseases, it may be helpful to understand the
anatomy of the cardiovascular system. It includes the following:
o Heart: the pump, divided into four chambers (R/L atria, R/L ventricles)
o Arteries: large vessels carrying oxygen-rich blood away from heart; have
thick, muscular wall
o Arterioles: smaller arteries
...
Angina pectoris and myocardial infraction.pptxSHIVANEE VYAS
Angina may feel like pressure or squeezing in your chest. The pain also can occur in your shoulders, arms, neck, jaw, or back. Angina pain may even feel like indigestion.
Angina is chest pain or discomfort that occurs if an area of your heart muscle doesn't get enough oxygen rich blood.
Dr. Mubashar A Choudry - Cardiovascular Diseases and their symptomsMubashar A Choudry MD
Cardiovascular disease comprises many different types of disease alone or in a group of disease. These types of disease can affects the arteries, veins, capillaries throughout the body.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
2. content
O Definition
O Causes
O Pathophysiology
O Types
O Clinical manifestation
O Frank starling phenomenon
O Pulmonary embolism and pulmonary edema
O prevention
O Complication
O Medical management
O Nursing management
3. Definition
O Heart failure
“ is the inability of the heart to pump
sufficient blood to meet the needs of tissues
for oxygen and nutrients ”
4.
5. causes
Left side Right side
1. Hypertension
2. Coarctation of aorta:
congenital condition
of narrowing aorta
3. Myocardial infarction
4. Cardiomyopathy
5. Aortic stenosis
6. Mitral regurgitation
1. Pulmonary
hypertension
2. Cor-pulmonale
3. Pulmonary
stenosis
4. Atrial septal defect
9. Types
1. Right sided HF : means that right side of heart not
pumping blood to lung as well as normal . Most
common cause is left side HF.
2. Left sided HF; when left ventricle don’t pump blood
out to body . And have two types:
Diastolic HF: the left ventricle losses it’s ability to
relax normally ( because muscles become stiff , the
heart can’t properly fill with blood during resting
period between each beat .
Systolic HF : left ventricle losses it’s ability to
contract normally ( heart not pump with enough force
to push enough blood into circulation .
11. Differentiation signs
right side
Peripheral congestion
:dependent edema and
ascites
Cyanosis
Fatigue
Distended jugular veins
Anorexia
Hepatomegaly or
spleenomegaly
Gi disteress and weight loss
left side
Pulmonary congestion:
crackles, wheezing , cough and
blood tinged sputum and
pulmonary edema :Paroxysmal
nocturnal dyspnea and
Orthopnea
Tachypnea
Dyspnea on exertion
Tachycardia
Cyanosis
Fatigue
Decrease cardiac output lead
to intolerance and tissue
perfusion are decreased :
restlessness
12. Frank starling phenomenon
O In increase workload on heart , the heart
dilated and increase in muscle mass (
hypertrophy )
O In dilatation the heart muscle fibers stretch
to increase the force of myocardial
contraction , which is called frank starling
phenomenon
13. Pulmonary embolism and
pulmonary edema
O Pulmonary embolism : is blood clot and
block blood vessels in lung
O Pulmonary edema : is fluid collection in
lung
17. Prevention
O The best way to prevent heart failureis to have a heart-healthy
lifestyleand control existing health problems like high blood
pressure and diabetes.
O To reduce your risk:
1. Don't smoke. If you smoke, quit. Avoid secondhand smoke too.
2. Eat heart-healthy foods. Eat fruits, vegetables, fish, lean meats, and
whole grains. Choose foods that are low in saturated fat and avoid trans
fat. Limit sodium, alcohol, and sugar.
3. Get regular exercise. Try to do activities that raise your heart rate. Aim
for at least 2½ hours ofmoderate exercise a week.1
4. Stay at a healthy weight. Lose weight if you need to.
5. Manage other health problemsthat can raise your risk of heart
disease and heart failure. These include high blood pressure,high
cholesterol, and diabetes. You can use heart-healthy lifestyle changes
along with medicines to manage these conditions
18. Complication
1. Atrial fibrillation
2. Kidney failure
3. Anemia : because of low perfussion to
kidney or kidney failure that lead to reduce
production of erythropioten that make RBC
.
4. Stroke
5. Heart valve condition ( mitral regurgitation
MR)
19. Medical management
O Upright position
O ACE-I , beta blocker , digoxin
O Lasix as diuretics
O Oxygen
O nitrates
O Restricted salt
O Reducing fluid
O Reducing afterload
20. Surgery AND other medical
procedure
O Surgery may need for
O Coronary artery bypass graft (CABG)
O Cardiac transplantation
O Angioplasty
O Valve replacement
O Left ventricular assist device
21. Nursing management
O Elevate legs for reducing edema
O Elevate head of bed
O give oxygen as ordered
O Give medication : digoxin , beta blocker ..
As ordered
O Teach : low – salt diet . Exercise but pace
activates , avoid extremes weather when
exercising