The patient recently went hiking and has developed leg paralysis. This is likely due to tick paralysis caused by a toxin secreted by certain tick species that blocks acetylcholine during feeding. Tick paralysis is most common in the Southeast in spring and summer. Removing the attached tick promptly can reverse the paralysis, so the doctor should conduct an examination to look for any remaining ticks and ensure removal of the culprit.
The presentation has been designed for non-medical people. Overview of few common diseases with preventive strategies. Diseases covered- Malaria, Dengue,Diarrhoeal diseases, Hepatitis,Viral Coryza,Conjunctivitis and Fungal Infections of Skin.
The presentation has been designed for non-medical people. Overview of few common diseases with preventive strategies. Diseases covered- Malaria, Dengue,Diarrhoeal diseases, Hepatitis,Viral Coryza,Conjunctivitis and Fungal Infections of Skin.
A simplified guide to the most common diseases with fever & rash especially in pediatrics. The data have been trimmed as much as possible and focused on spot visual diagnosis of the disease.
An insect that has an elongated body and a segmented, curved tail tipped with a venomous stinger.
A sting can be fatal to a person who is allergic to it.
The toxicity of scorpion venom varies by species. A given species' venom may contain many chemicals, some toxic to insects, others toxic to mammals.
Scorpion species with smaller and more slender claws generally have more toxic venom.
Scorpion stings are much more dangerous for infants and small children.
Two Cases of Fever in returned travelers - Slideset by Professor Ivan HungWAidid
This slideset by Professor Ivan Hung analyzes two different cases of fever in returned travelers: history, differentials, diagnosis and management, indicating also signs, symptoms and how to prevent it.
A simplified guide to the most common diseases with fever & rash especially in pediatrics. The data have been trimmed as much as possible and focused on spot visual diagnosis of the disease.
An insect that has an elongated body and a segmented, curved tail tipped with a venomous stinger.
A sting can be fatal to a person who is allergic to it.
The toxicity of scorpion venom varies by species. A given species' venom may contain many chemicals, some toxic to insects, others toxic to mammals.
Scorpion species with smaller and more slender claws generally have more toxic venom.
Scorpion stings are much more dangerous for infants and small children.
Two Cases of Fever in returned travelers - Slideset by Professor Ivan HungWAidid
This slideset by Professor Ivan Hung analyzes two different cases of fever in returned travelers: history, differentials, diagnosis and management, indicating also signs, symptoms and how to prevent it.
Internal Medicine Board Review - Nephrology Flashcards - by KnowmedgeKnowmedge
Internal Medicine Board Review Flashcards - This eBook contains 50 Nephrology / Urology Flashcards. The Flashcards are review questions and can be used to study for medical board exams including the USMLE Step Exams and the ABIM Internal Medicine Exam. More questions can be found at www.knowmedge.com
This is a power point i did in 2010 in Gateway. It is about zoonotic diseases that animals can get. I chose to do this as i wanted to be a vet or vet nurse
Dengue fever- a medical study ( definition, management ,prevention ,risks ,pa...martinshaji
#Dengue fever is a mosquito-borne disease that occurs in #tropical and #subtropical areas of the #world. Mild dengue fever causes high fever, #rash, and #muscle and #joint pain. A severe form of dengue #fever, also called dengue #hemorrhagic fever, can cause severe #bleeding, a sudden drop in #blood pressure (#shock) and #death.
#Millions of cases of dengue infection occur #worldwide each year. Dengue fever is most common in #Southeast #Asia and the #western #Pacific #islands, but the #disease has been increasing rapidly in #Latin #America and the #Caribbean
please comment
thank you
"Venomous Encounters: Understanding the Physiology, Treatment, and Prevention...krjx9cpvdg
Snake bites epitomize a multifaceted intersection between humans and reptiles, often culminating in dire consequences. The intricate dynamics of venom delivery mechanisms and their intricate interplay with the human physiology underscore the urgency of comprehensively understanding and addressing this complex issue.
Venomous snakes, equipped with specialized fangs honed by evolution, wield venom as a potent weapon. This venom, a sophisticated blend of toxins, serves diverse purposes, including immobilizing prey, aiding in digestion, and self-defense. The composition of snake venom varies markedly across species, each venom boasting a unique concoction of enzymes, peptides, and proteins meticulously tailored to disrupt physiological functions in their unsuspecting victims.
The ramifications of a snake bite can be profound and diverse, spanning from localized tissue damage and systemic toxicity to potentially life-threatening complications. The severity of envenomation hinges on myriad factors, including the potency of the venom, the volume injected, the site of the bite, and the health status of the victim. Neurotoxic venoms, for instance, can precipitate paralysis and respiratory failure, while hemotoxic venoms may induce extensive tissue necrosis and coagulopathies, underscoring the pernicious diversity of snakebite outcomes.
Timely recognition and appropriate management are pivotal in mitigating the impact of snake bites. Immediate implementation of first aid measures, such as immobilizing the affected limb, maintaining the victim's composure, and promptly seeking medical assistance, can substantially ameliorate outcomes. In regions where venomous snakes hold sway, access to antivenom and proficient healthcare professionals assumes paramount importance for efficacious treatment.
Nonetheless, the challenges posed by snake bites transcend the confines of mere medical intervention. Socioeconomic determinants, encompassing factors like limited healthcare accessibility, inadequate infrastructure, and geographical remoteness, can markedly exacerbate the burden of snakebite-related morbidity and mortality, particularly among marginalized populations.
Preventive strategies wield considerable influence in curtailing the incidence of snake bites and attenuating their repercussions. Educational initiatives geared toward disseminating knowledge about snake behavior, imparting proficiency in first aid techniques, and advocating preventive measures like donning protective attire and circumventing high-risk locales constitute indispensable pillars of snakebite prevention.
Furthermore, endeavors aimed at conserving snake habitats and fostering cohabitation between humans and serpents are pivotal for long-term snakebite mitigation. By fostering an understanding of the ecological roles of snakes and championing their conservation, societies can engender an environment conducive to harmonious coexistence between humans and reptiles.
An overview of the most commonly encountered emergencies in endurance athletes. The Baker to Vegas Law Enforcement Relay Race is the Largest of its kind in the world. This Year over 7000 runners will be competing in the 120 mile race.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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2. Just got back from Africa…
Flu like symptoms
Bleeding
??????
3. Marburg and Ebola Viruses
What to look for…
Recent travel (specifically Africa)
Hemorrhagic fever 7-10 days after
exposure
Head ache, fever, myalgias,
arthralgias, lethargy
GI – N/V/D
Bleeding from the nose, mouth,
rectum, eyes and ears
4. Marburg and Ebola Viruses
Labs – Thrombocytopenia,
Hemorrhagic anemia (specifically
GI med student finger positive)
ELISA and PCR for confirmation
Management Supportive (death
is common)
5. Parents find a bat in an infants
room when they wake up in the
AM.
What are you worried about?
6. Rabies
Roughly 3 cases per year in the US
however 40,000 deaths / yr
worldwide
Most common bites for Dogs and
Bats
7. Rabies
HIGH RISK
Raccoon
Skunk (not spray)
Fox
Bats
Coyote
Bite from larger
carnivore in endemic
area
LOW RISK
Domestic animals
Small rodents
Lagomorphs
Groundhogs /
Woodchucks based on
if area is endemic
SMALL ANIMALS ARE
KILLED WHEN BITTEN
8. Rabies
Rhabdovirus transmitted though saliva
into wound or mucous membrane
Replicates in muscle cells near bite site
and stays at site during incubation period
for 30 TO 90 DAYS. Head or neck is
shorter
Tracks through peripheral nerves to brain
stem, replicates, then enters salivary
glands
9. Rabies Symptoms
Prodrome ->URI / GI viral like
symptoms
Rabies Fury (encephalitis)->
agitation, irritable, hallucinations,
ataxia, weakness, sz
Aerophobia then Hydrophabia
Coma after one week followed
quickly by death
10. Rabies Dx
History, History, History
Bite or exposure to suspected animal
Animal should be observed for 10 DAYS
with animal vaccination hx obtained
Travel to endemic area South West
(SoCal spared), NorCal, Midwest, East
Brain Biopsy
11. Rabies Management
Clinical Rabies? – Sorry! Otherwise,
Post Exposure Prophylaxis!!!
PEP for bats with no history or signs
if in room while sleeping or
unattended child or someone with
dementia
12. Rabies PEP
Scrubbing with soap within 3 hours nearly
100% effective (Benzalkonium chloride,
povidone-iodide)
Passive immunity Human Rabies
Immunoglobulin (HRIG) 20 IU/kg as much as
possible in and arround wound, the rest at distant
site IM (must be 2 sites)
Active immunity Human diploid cell
vaccine (HDCV)
If no previous vacc then 1ml IM deltoid on days
0,3,7,14,28
If previously vacc then days 0,3
15. Small Pox (Variola) Sympt
Prodrome fever, malaise, back
pain, myalgias
Rash was often confused with
varicella
Macules
/ Papules that progress to
pustules over 1 to 2 days
Uniform progression (unlike vericalla)
Centerfugal distribution usually face
and oral mucosa first
16. Small Pox (Variola) Dx
If clinically suspected..
Viral swab of oral mucosa or open
pustule
Then call CDC and authorities for
suspected terrorist attack
17. Small Pox (Variola) Management
Contact and droplet iso
Iso family and close contacts
Vaccination and immunoglobulin
Supportive once rash appears
18. Pt returned from (insert 3rd world
country) now low grade fever
which has been spiking high, flu
like symptoms and very dark urine
with a positive VDRL????
23. Malaria Management
Uncomplicated Chloroquine (Haiti,
Dominican Rep, Central America parts of
Middle East)
Chloroquine Resistance? Quinine +
Doxy
P. Falciparum? IV quinine or quinidine
(causes profound hypoglycemia and
dysrythmias)
Primaquine? hepatic phases of P. ovale
and vivax – after testing for G6PD
25. Sporotrichosis Etiology
Fungal infection by Sporothrix
scheenckii
Mold
on plants– Roses
Cats, Armidillos
Inoculation into skin
Farmers, gardeners, forestry
workers
26. Sporotrichosis Hx/Symptoms
Acute:
Painless red papule
or papules
Lesions can be
delayed up to a
month post
exposure
Lymphocutaneous
spread
Chronic:
Skin leasions may
persist
intermittently for
years
Pulm involvement
with cough, fever,
and weight loss
Osteomylitis,
tenosynovitis,
osteomyelitis
CNS unlikely
27. Sporotrichosis Dx/Management
Organisms found in skin bx or body
fluid (blood, sputum, joint fluid)
MANAGEMENT
CUTANEOUS
ONLY months of azole tx
DISSIMINATED
Itraconazole if well appearing
Amphotericin if sick
31. Babesiosis
THE MALARIA OF NORTH EAST USA
Protazoan Maria-like parasite
Babesia
Multiplies in RBC’s resulting in
hemolysis then microvasculature
has sludging effect
Vector Ixodes (dammini, scapularis,
pacificus) with primary reservoir
white footed mouse
32. Babesiosis Symptoms/Signs/Dx
Fevers, myalgias, dark urine, headache,
fatigue
Hepatospleenomegally, anemia,
thrombocytopenia, increased LFT’s and
LDH
Giemsa and Wright stains on peripheral
smears reveal rings
Tetrad forms on smear is pathognomonic
34. I went hiking and got a tick bite. A
few days later I got a fever. A few
days after that it went away. A few
days after that it came back and
now I feel like crap. What do I
have??
35. Colorado Tick Fever
Western US and Germany
Dermacentor Andersoni (wood tick)
Can get with concurrent Rocky
Mountain Spotted Fever
Incubation of 3-6 days after tick
bite
36. Colorado Tick Fever
Symptoms/Signs:
1
Acute chills,
lethargy, H/A,
photophobia, abd
pain, severe
myalgias
2
Fever breaks
after 2-3 days
3
Recurs for
another 3 days
Management:
Supportive
38. Lyme Disease
Most common tick disease
North central to Northeastern and
Mid Atlantic areas --- also global
Spirochete – Borrelia Burgdorferi
Tick – Ixodes dammini
Primary reservoir is field mouse
Transmission 2 days after tick
attachment
39. Lyme Disease
Early:
Erythema Migrans
Secondary spread to
palms and soles
H/A (meningeal
irritation)
Hepatitis / Pharyngitis
Acute Disseminated:
Neuro findings (4
wks)
Meningeoencephalitis,
cranial neuropathy
(Bells) which can be
bilateral, extremity
radiculopathy with
assymetric
pain/weakness
Cardiac (3-5 wks)AV
block is most common
with gradual resolution
Arthritis (wksmonths)mono or
polyarticular
asymmetric arthritis
Late: (>1 yr)
10% chronic arthritis
Neuro fatigue
syndromes, chronic
encephalopathy
(memory impairment,
hypersomnolence, mild
psych)
40. Lyme Disease Dx
Only some pts report tick bite <50%
EM is diagostic
IgM peaks at 3-6 weeks then
nondiagnostic
IgG dectable at 2mo, peaks at 12 mo
ELISA, Western blot, PCR for confirmation
Lumbar puncture if neuro Lyme
41. Lyme Disease Management
Vaccination and Doxy
prophylax single dose
(72 hours after finding
an engorged tick) only
in high risk areas
Early Lyme Dz Doxy
100 Bid X 3wks
If Preg or Peds
amoxicillin
Jarish-Herxhiemer
rxn fever,
tachycardia, mylaise,
h/a (ASA/Rest for tx)
Early Disseminated
Doxy or amox X 1
month and no steroids
for Bells
Meningitis/Enceph –
IV Ceftriaxone or PCN
Cardiac first degree –
doxy or amox for 2130 days
Cardiac high degreeAdmit to tele, IV
Ceftriaxone or PCN
42. Lyme Disease Management
Late Dz:
Arthritis
Doxy or Amox for 30 days if
persistant 2nd course OR 2-4wks IV
Ceftriaxone
Neuro
Ceftriaxone 2 G daily for 2 -4
wks often with no complete resolution
of symptoms
43. WUZ GATOR HUNTIN WITH MY
CUZ/WIFE AND I SAW A TICK ON
ME!! NOW I’M SICK!! WHAT IS
IT DOC??? (in July)
44. Erlichiosis
Spotless RMSF
Summer Dz
Endemic South Central and South
Atlantic
Tick Ixodes scapularis
Gram neg coccbacilli -- Organisms
live in the leukocytes
Onset 9 days after bite (most pts
90% report bite)
48. Rocky Mountain Spotted Fever
5% mortality
Endemic in 48 contiguous states except
Maine– Most prevalent in Southeast
Ricketia Rickettsii–
Obligate intracellular gram neg coccobacillus
Orginisms multiply in vascular endothelium
and smooth muscle
Cause tPA and VWF release
Ticks – Dermacentor anderosi and
variabilis (wood tick and dog tick). All
warm blooded animals are resevoir
49. RMSF signs/symptoms
Tick bite history in most
Abrupt onset of symptoms:
h/a,
myalgias, N/V, abd mm myositis,
calf tenderness
Rumple-Leede phenom– petechiae
after BP cuff
Centripital Rash – initial pink/red
blanchable macules, may involve palms
and soles
52. Went hiking a week ago and now I
can’t move my legs. What do I
have and can you fix me?
53. TICK PARALYSIS
Most common in Southeast in spring
and summer
Dermacentor Species – toxin
secreted in salivary glands during
blood meal blocks acetylcholine
release
54. TICK PARALYSIS
Signs Symptoms:
Restlessness and
irritability 4-7 days
Then ascending
flacid paralysis +/ataxia
Loss of DTRs,
bulbar involvement
then resp paralysis
Management
Remove Tick
Improvement in a
few hours and
recovery within 48
hours
57. Tularemia
Most common in southwest
Untreated mortality 5-30%
Treated <1%
Francisella tularenis Gram neg
pleomorphic bacillus
Reservoirs RABITS, domestic cat, Tick
(Amblyomma Americanum and
Dermacento Variabilis)
Mode of transmission dictates illness
58. Tularemia Manifestations
Ulceroglandular
Most common
Ulceration of papules 2
days after tick innoculation
Glandular
2nd most common
Lymphadenopathy without
ulceration
Unilateral conjunctivitis
with regional adenopathy
Systemic dz without
identified entry site
f/c/abd pain/ night sweats
Pulmonary
Oculoglandular
Typhoidal
Direct inhalation
Similar to bacterial
pneumonia
Concern for bio warfare
Oropharyngeal
Least Common
Undercooked rabbit meat
Nonspecific GI issues… may
progress to GI bleed
59. Tularemia Dx/ Management
Dx:
Clinical history
Bubos
Seerologic testing
Do not aspirate LN
due to risk of
transmission to
health care worker
MaInagement:
Isolation not
required
Streptomysin for
active dz
PEP Doxy 100 BID
X 14 days
62. Infectious Control Droplet
Particles > 5 microns
Neg pressure not required
Doors may be open
Standard precautions with mask when
within
3FT of pt
Meningitis, diptheria, pertussis, plague,
bacterial pneumonia, scarlet fever,
adenovirus, mumps, parvovirus
63. Occupational Exposure
Hep B blood exposure
Consider booster if >10 yrs if prior
immunization and > 10mIU/ml 3 months after
3rd dose
If Prior immunization but non responder HBIG
and Vaccine concurrently or HBIG at injury and
again 1 month later
Unkown titers then draw and treat depending
on results if lab results > 48 hours then treat
No prior immunization same options as
nonresponder
64. Occupational Exposure
Hep C blood exposure
Transmission
is approximately 2-7%
Good Luck!! No treatment or
vaccination exists
65. Occupational Exposure
HIV blood exposure
Risk of all percutaneous exposure 0.3% if
source is HIV positive
Viral load of source makes a difference
Mucous memb exposure with blood risk 0.1%
PEP Recommend only for high risk exposure
including
Pt with AIDS plus mucous memb or skin
compramise
Patients with symptomatic HIV
Acute seroconversion
High Viral load >1500 copies/ml
66. Occupational Exposure
HIV blood exposure
Regimen:
Zidovudine and Lamivudine X 1 month
Administer as soon as possible
May be ineffective if started > 24 hours