SlideShare a Scribd company logo
SCORPION
VENOM
SCORPION VENOM
An insect that has
elongated body
a segmented,
curved tail tipped
with a venomous
stinger.
A sting can be fatal
to a person who is
allergic to it.
The toxicity of scorpion
venom varies by species. A
given species' venom may
contain many chemicals,
some toxic to insects,
toxic to mammals.
Scorpion species
with smaller and
more slender claws
generally have
toxic venom.
Scorpion stings are
much more
dangerous for
infants and small
children.
PATHOPHYSIOLOGY
oGrade 1: Local pain and paresthesias at the
sting site. The puncture wound may not be
noticeable in this grade. The "tap test" may
confirm a provider's suspicion by distracting the
patient and tapping on the area of the sting,
causing increased pain. This does not occur
other species. Care is limited to analgesia.
oGrade 2: Local pain and paresthesias at the
sting site as well as proximally. Recommended
care again includes analgesia with optional
When serious symptoms do occur, they are usually due to the Centruroides
species. Because of this, a classification scale has been created to grade each
envenomation by a Centruroides scorpion.
PATHOPHYSIOLOGY
o Grade 3: Grade 2 with added cranial nerve (increased oral secretions,
blurry vision, rapid tongue movement, nystagmus) or skeletal
neuromuscular dysfunction (flailing of the extremities and tetanus-like
arching of the back). These patients require analgesia and anxiolytics as
well as antivenom.
o Grade 4: Unlike grade 3 envenomations where the patient will
experience either cranial nerve or skeletal muscle dysfunction, grade 4
envenomations include both. This can cause hyperthermia,
rhabdomyolysis, pulmonary edema, and multiple organ failures.
antivenom is critical in this situation.
SIGNS AND SYMPTOMS
• Signs and symptoms at the site of the sting
may include:
– Pain, which can be intense
– Numbness and tingling in the area
the sting
– Slight swelling in the area around the
Most scorpion stings cause only localized signs and
symptoms, such as pain and warmth at the site of the sting.
Sometimes these symptoms may be quite intense, even if you
don't see redness or swelling.
SIGNS AND SYMPTOMS
• Signs and symptoms related to widespread (systemic) venom effects usually
occur in children who are stung and may include:
– Difficulty breathing
– Muscle twitching or thrashing
– Unusual head, neck and eye movements
– Drooling
– Sweating
– Nausea and vomiting
– High blood pressure (hypertension)
– Accelerated heart rate (tachycardia) or irregular heart beat (arrhythmia)
– Restlessness or excitability or inconsolable crying (in children)
HISTORY AND PHYSICAL EXAMINATION
• Most scorpion stings cause a local inflammatory reaction and pain.
• When the venom affects the sodium channels, this may manifest as
seizure-like activity in the patient and obscure the clinical picture,
especially when the child or infant is unable to relay an accurate history.
• Intubation may be required in these patients, as motor hyperactivity of
the pharyngeal muscles and uncontrolled diaphragmatic and intercostal
neuromuscular activity may be seen.
• These symptoms may progress quickly, causing impending airway
collapse.
• In the select species causing cardiopulmonary effects, tachycardia,
pulmonary edema, and more importantly, cardiogenic shock may be
seen.
• While uncommon, local tissue necrosis in days to weeks after the initial
TREATMENT
moving the patient away from the
scorpion
stabilizing the patient's airway and
vital signs
administration of antivenin
institution of symptomatic and local
treatment.
LOCAL TREATMENT
Calm the patient
• to lower the heart rate and blood pressure, thus limiting the spread of the venom.
Use ice bags
• to reduce pain and to slow the absorption of venom via vasoconstriction.
• This is most effective during the first 2 hours following the sting.
Administer local wound care.
Apply a topical or local anesthetic agent to the wound to decrease
paresthesia
Administer muscle relaxants for severe muscle spasms
Administer tetanus prophylaxis
Administer systemic antibiotics if signs of secondary infection occur.
LOCAL TREATMENTapplying a lymphatic-venous compression wrap 1 inch proximal to the
sting site
• For medical delay of secondary infection
• to reduce superficial venous and lymphatic flow of the venom but not to stop the
arterial flow.
• Only remove this wrap when the provider is ready to administer systemic support.
Immobilize the affected part in a functional position below the level of the
heart
SYSTEMIC TREATMENT
Establish airway, breathing, and circulation (ie, ABCs)
Monitor vital signs
Use invasive monitoring for patients who are unstable and
hemodynamic.
Administer oxygen.
Administer intravenous fluids to help prevent hypovolemia
Perform intubation and institute mechanical ventilation
Administer atropine to counter venom-induced
parasympathomimetic effects.
SYSTEMIC TREATMENT
HYPERDYNAMIC CARDIOVASCULAR CHANGES
administration of a combination of beta-blockers with sympathetic alpha-
blockers is most effective in reversing this venom-induced effect.
• Avoid using beta-blockers alone because this leads to an unopposed alpha-adrenergic
effect.
nitrates can be used for hypertension and myocardial ischemia.
diuretic may be used for pulmonary edema in the absence of hypovolemia
• afterload reducer, such as prazosin, nifedipine, nitroprusside, hydralazine, or
angiotensin-converting enzyme inhibitors, is better.Inotropic medications, such as digitalis, have little effect, while dopamine
aggravates the myocardial damage through catecholamine-like actions.
pressor such as norepinephrine to correct hypotension refractory to fluid
therapy.
Scorpion venom

More Related Content

What's hot

Snake Bite.ppt
Snake Bite.pptSnake Bite.ppt
Snake Bite.ppt
Vikas Kesarwani
 
Scorpion sting
Scorpion stingScorpion sting
Scorpion sting
ikramdr01
 
Snakebite
SnakebiteSnakebite
Snakebite
arnab ghosh
 
Plant poisoning
Plant poisoning Plant poisoning
Plant poisoning
hodmedicine
 
Snake & Snake bites
Snake & Snake bitesSnake & Snake bites
Snake & Snake bites
Dr. Aryan (Anish Dhakal)
 
Aluminium Phosphide Poisoning
Aluminium Phosphide PoisoningAluminium Phosphide Poisoning
Aluminium Phosphide Poisoning
autumnpianist
 
Plant poison
Plant poisonPlant poison
Plant poison
Praba Karan
 
Snake bite
Snake biteSnake bite
Snake bite
Sachin Verma
 
snake bite management
snake bite managementsnake bite management
snake bite management
Shivshankar Badole
 
Organophosphate poisoning and its management (Clinical Toxicology)
Organophosphate poisoning and its management (Clinical Toxicology)Organophosphate poisoning and its management (Clinical Toxicology)
Organophosphate poisoning and its management (Clinical Toxicology)
Soujanya Pharm.D
 
Bites and Stings emergency medicine
Bites and Stings emergency medicineBites and Stings emergency medicine
Bites and Stings emergency medicine
Lijo Joy
 
Snake bite management
Snake bite managementSnake bite management
Snake bite management
laddha1962
 
Snake bite .. scorpion sting
Snake bite .. scorpion stingSnake bite .. scorpion sting
Snake bite .. scorpion sting
Ahmed Essam
 
General toxicology
General toxicology General toxicology
General toxicology
imrana tanvir
 
Organophosphate poisoning
Organophosphate poisoningOrganophosphate poisoning
Organophosphate poisoning
Dhananjay Gupta
 

What's hot (20)

Animal Poisons
Animal PoisonsAnimal Poisons
Animal Poisons
 
Snake Bite.ppt
Snake Bite.pptSnake Bite.ppt
Snake Bite.ppt
 
Scorpion sting
Scorpion stingScorpion sting
Scorpion sting
 
Snake poisoning
Snake poisoningSnake poisoning
Snake poisoning
 
Snakebite
SnakebiteSnakebite
Snakebite
 
Plant poisoning
Plant poisoning Plant poisoning
Plant poisoning
 
Snake & Snake bites
Snake & Snake bitesSnake & Snake bites
Snake & Snake bites
 
Toxicity of pesticides
Toxicity of pesticidesToxicity of pesticides
Toxicity of pesticides
 
Aluminium Phosphide Poisoning
Aluminium Phosphide PoisoningAluminium Phosphide Poisoning
Aluminium Phosphide Poisoning
 
Oleandrin
OleandrinOleandrin
Oleandrin
 
Plant poison
Plant poisonPlant poison
Plant poison
 
Snake bite
Snake biteSnake bite
Snake bite
 
snake bite management
snake bite managementsnake bite management
snake bite management
 
Organophosphate poisoning and its management (Clinical Toxicology)
Organophosphate poisoning and its management (Clinical Toxicology)Organophosphate poisoning and its management (Clinical Toxicology)
Organophosphate poisoning and its management (Clinical Toxicology)
 
Electrocution
ElectrocutionElectrocution
Electrocution
 
Bites and Stings emergency medicine
Bites and Stings emergency medicineBites and Stings emergency medicine
Bites and Stings emergency medicine
 
Snake bite management
Snake bite managementSnake bite management
Snake bite management
 
Snake bite .. scorpion sting
Snake bite .. scorpion stingSnake bite .. scorpion sting
Snake bite .. scorpion sting
 
General toxicology
General toxicology General toxicology
General toxicology
 
Organophosphate poisoning
Organophosphate poisoningOrganophosphate poisoning
Organophosphate poisoning
 

Similar to Scorpion venom

Snake envenomation
Snake envenomationSnake envenomation
Snake envenomationHanan Fathy
 
Snake Bite and Scorpion Stings,(Kurdistan)
Snake Bite and Scorpion Stings,(Kurdistan)Snake Bite and Scorpion Stings,(Kurdistan)
Snake Bite and Scorpion Stings,(Kurdistan)
Znar Mzuri
 
Snake bites
Snake bitesSnake bites
Snake bites
Mayank Jain
 
Snake bite and its management by first aid and antivenom
Snake bite and its management by first aid and antivenomSnake bite and its management by first aid and antivenom
Snake bite and its management by first aid and antivenom
ShwetaKhadka
 
Complications of local anesthesia
Complications of local anesthesiaComplications of local anesthesia
Complications of local anesthesia
Nishant Kumar
 
"Venomous Encounters: Understanding the Physiology, Treatment, and Prevention...
"Venomous Encounters: Understanding the Physiology, Treatment, and Prevention..."Venomous Encounters: Understanding the Physiology, Treatment, and Prevention...
"Venomous Encounters: Understanding the Physiology, Treatment, and Prevention...
krjx9cpvdg
 
neurological manifestations of scorpion sting
neurological manifestations of scorpion stingneurological manifestations of scorpion sting
neurological manifestations of scorpion stingdrnaveent
 
Poisoning snake2012+MCQs.
Poisoning snake2012+MCQs.Poisoning snake2012+MCQs.
Poisoning snake2012+MCQs.
Shaikhani.
 
Snake bite final (2)
Snake bite final (2)Snake bite final (2)
Snake bite final (2)
Rahul Rai
 
Bites And Stings
Bites And StingsBites And Stings
Bites And Stings
pdhpemag
 
Allergic shock
Allergic shockAllergic shock
Allergic shockpsaltakis
 
Snake bite in pediatrics
Snake bite in pediatricsSnake bite in pediatrics
Snake bite in pediatrics
vinay nandimalla
 
Poisonous insects toxicology 6 th sem
Poisonous insects toxicology 6 th semPoisonous insects toxicology 6 th sem
Poisonous insects toxicology 6 th sem
sanam maharjan
 
Complications of local anesthesia
Complications of local anesthesiaComplications of local anesthesia
Complications of local anesthesia
Salabh Parihar
 
OCULAR EMERGENCIES
OCULAR EMERGENCIESOCULAR EMERGENCIES
OCULAR EMERGENCIES
IVRI
 
2.seizure.pptx
2.seizure.pptx2.seizure.pptx
2.seizure.pptx
MesfinShifara
 
Presentation emergency medicine
Presentation emergency medicinePresentation emergency medicine
Presentation emergency medicine
Lijo Joy
 
OBSTETRICIAN’s PERSPECTIVE OF LABOUR ANALGESIA.pptx
OBSTETRICIAN’s PERSPECTIVE OF LABOUR ANALGESIA.pptxOBSTETRICIAN’s PERSPECTIVE OF LABOUR ANALGESIA.pptx
OBSTETRICIAN’s PERSPECTIVE OF LABOUR ANALGESIA.pptx
Ammu Sujatha
 

Similar to Scorpion venom (20)

Project on snake bite
Project on snake biteProject on snake bite
Project on snake bite
 
Snake envenomation
Snake envenomationSnake envenomation
Snake envenomation
 
Snake Bite and Scorpion Stings,(Kurdistan)
Snake Bite and Scorpion Stings,(Kurdistan)Snake Bite and Scorpion Stings,(Kurdistan)
Snake Bite and Scorpion Stings,(Kurdistan)
 
Snake bites
Snake bitesSnake bites
Snake bites
 
Snake bite and its management by first aid and antivenom
Snake bite and its management by first aid and antivenomSnake bite and its management by first aid and antivenom
Snake bite and its management by first aid and antivenom
 
Complications of local anesthesia
Complications of local anesthesiaComplications of local anesthesia
Complications of local anesthesia
 
"Venomous Encounters: Understanding the Physiology, Treatment, and Prevention...
"Venomous Encounters: Understanding the Physiology, Treatment, and Prevention..."Venomous Encounters: Understanding the Physiology, Treatment, and Prevention...
"Venomous Encounters: Understanding the Physiology, Treatment, and Prevention...
 
neurological manifestations of scorpion sting
neurological manifestations of scorpion stingneurological manifestations of scorpion sting
neurological manifestations of scorpion sting
 
Poisoning snake2012+MCQs.
Poisoning snake2012+MCQs.Poisoning snake2012+MCQs.
Poisoning snake2012+MCQs.
 
Snake bite final (2)
Snake bite final (2)Snake bite final (2)
Snake bite final (2)
 
Bites And Stings
Bites And StingsBites And Stings
Bites And Stings
 
Allergic shock
Allergic shockAllergic shock
Allergic shock
 
Snake bite in pediatrics
Snake bite in pediatricsSnake bite in pediatrics
Snake bite in pediatrics
 
Poisonous insects toxicology 6 th sem
Poisonous insects toxicology 6 th semPoisonous insects toxicology 6 th sem
Poisonous insects toxicology 6 th sem
 
Complications of local anesthesia
Complications of local anesthesiaComplications of local anesthesia
Complications of local anesthesia
 
OCULAR EMERGENCIES
OCULAR EMERGENCIESOCULAR EMERGENCIES
OCULAR EMERGENCIES
 
2.seizure.pptx
2.seizure.pptx2.seizure.pptx
2.seizure.pptx
 
Presentation emergency medicine
Presentation emergency medicinePresentation emergency medicine
Presentation emergency medicine
 
Medical Conditions2
Medical Conditions2Medical Conditions2
Medical Conditions2
 
OBSTETRICIAN’s PERSPECTIVE OF LABOUR ANALGESIA.pptx
OBSTETRICIAN’s PERSPECTIVE OF LABOUR ANALGESIA.pptxOBSTETRICIAN’s PERSPECTIVE OF LABOUR ANALGESIA.pptx
OBSTETRICIAN’s PERSPECTIVE OF LABOUR ANALGESIA.pptx
 

More from Sawsan Monir

Dendrimers for Target Drug Delivery In Treatment of Cancer
Dendrimers for Target Drug Delivery In Treatment of CancerDendrimers for Target Drug Delivery In Treatment of Cancer
Dendrimers for Target Drug Delivery In Treatment of Cancer
Sawsan Monir
 
treatment of Mushroom toxicity
treatment of Mushroom toxicitytreatment of Mushroom toxicity
treatment of Mushroom toxicity
Sawsan Monir
 
Nano spray drying technology for heat sensitive biopharmaceuticals
Nano spray drying technology for heat sensitive biopharmaceuticalsNano spray drying technology for heat sensitive biopharmaceuticals
Nano spray drying technology for heat sensitive biopharmaceuticals
Sawsan Monir
 
Decision analysis & Markov chain
Decision analysis & Markov chainDecision analysis & Markov chain
Decision analysis & Markov chain
Sawsan Monir
 
Marketing
MarketingMarketing
Marketing
Sawsan Monir
 
Monosomy 7
Monosomy 7Monosomy 7
Monosomy 7
Sawsan Monir
 

More from Sawsan Monir (6)

Dendrimers for Target Drug Delivery In Treatment of Cancer
Dendrimers for Target Drug Delivery In Treatment of CancerDendrimers for Target Drug Delivery In Treatment of Cancer
Dendrimers for Target Drug Delivery In Treatment of Cancer
 
treatment of Mushroom toxicity
treatment of Mushroom toxicitytreatment of Mushroom toxicity
treatment of Mushroom toxicity
 
Nano spray drying technology for heat sensitive biopharmaceuticals
Nano spray drying technology for heat sensitive biopharmaceuticalsNano spray drying technology for heat sensitive biopharmaceuticals
Nano spray drying technology for heat sensitive biopharmaceuticals
 
Decision analysis & Markov chain
Decision analysis & Markov chainDecision analysis & Markov chain
Decision analysis & Markov chain
 
Marketing
MarketingMarketing
Marketing
 
Monosomy 7
Monosomy 7Monosomy 7
Monosomy 7
 

Recently uploaded

Neuro Saphirex Cranial Brochure
Neuro Saphirex Cranial BrochureNeuro Saphirex Cranial Brochure
Neuro Saphirex Cranial Brochure
RXOOM Healthcare Pvt. Ltd. ​
 
Telehealth Psychology Building Trust with Clients.pptx
Telehealth Psychology Building Trust with Clients.pptxTelehealth Psychology Building Trust with Clients.pptx
Telehealth Psychology Building Trust with Clients.pptx
The Harvest Clinic
 
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...
The Lifesciences Magazine
 
How many patients does case series should have In comparison to case reports.pdf
How many patients does case series should have In comparison to case reports.pdfHow many patients does case series should have In comparison to case reports.pdf
How many patients does case series should have In comparison to case reports.pdf
pubrica101
 
Demystifying-Gene-Editing-The-Promise-and-Peril-of-CRISPR.pdf
Demystifying-Gene-Editing-The-Promise-and-Peril-of-CRISPR.pdfDemystifying-Gene-Editing-The-Promise-and-Peril-of-CRISPR.pdf
Demystifying-Gene-Editing-The-Promise-and-Peril-of-CRISPR.pdf
SasikiranMarri
 
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptx
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptx
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptx
R3 Stem Cell
 
VVIP Dehradun Girls 9719300533 Heat-bake { Dehradun } Genteel ℂall Serviℂe By...
VVIP Dehradun Girls 9719300533 Heat-bake { Dehradun } Genteel ℂall Serviℂe By...VVIP Dehradun Girls 9719300533 Heat-bake { Dehradun } Genteel ℂall Serviℂe By...
VVIP Dehradun Girls 9719300533 Heat-bake { Dehradun } Genteel ℂall Serviℂe By...
rajkumar669520
 
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
ranishasharma67
 
.Metabolic.disordersYYSSSFFSSSSSSSSSSDDD
.Metabolic.disordersYYSSSFFSSSSSSSSSSDDD.Metabolic.disordersYYSSSFFSSSSSSSSSSDDD
.Metabolic.disordersYYSSSFFSSSSSSSSSSDDD
samahesh1
 
Myopia Management & Control Strategies.pptx
Myopia Management & Control Strategies.pptxMyopia Management & Control Strategies.pptx
Myopia Management & Control Strategies.pptx
RitonDeb1
 
HEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptxHEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptx
priyabhojwani1200
 
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Guillermo Rivera
 
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and BeyondEmpowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Health Catalyst
 
Health Education on prevention of hypertension
Health Education on prevention of hypertensionHealth Education on prevention of hypertension
Health Education on prevention of hypertension
Radhika kulvi
 
CONSTRUCTION OF TEST IN MANAGEMENT .docx
CONSTRUCTION OF TEST IN MANAGEMENT .docxCONSTRUCTION OF TEST IN MANAGEMENT .docx
CONSTRUCTION OF TEST IN MANAGEMENT .docx
PGIMS Rohtak
 
Contact ME {89011**83002} Haridwar ℂall Girls By Full Service Call Girl In Ha...
Contact ME {89011**83002} Haridwar ℂall Girls By Full Service Call Girl In Ha...Contact ME {89011**83002} Haridwar ℂall Girls By Full Service Call Girl In Ha...
Contact ME {89011**83002} Haridwar ℂall Girls By Full Service Call Girl In Ha...
ranishasharma67
 
Roti bank chennai PPT [Autosaved].pptx1
Roti bank  chennai PPT [Autosaved].pptx1Roti bank  chennai PPT [Autosaved].pptx1
Roti bank chennai PPT [Autosaved].pptx1
roti bank
 
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfCHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
Sachin Sharma
 
Surgery-Mini-OSCE-All-Past-Years-Questions-Modified.
Surgery-Mini-OSCE-All-Past-Years-Questions-Modified.Surgery-Mini-OSCE-All-Past-Years-Questions-Modified.
Surgery-Mini-OSCE-All-Past-Years-Questions-Modified.
preciousstephanie75
 
Artificial Intelligence to Optimize Cardiovascular Therapy
Artificial Intelligence to Optimize Cardiovascular TherapyArtificial Intelligence to Optimize Cardiovascular Therapy
Artificial Intelligence to Optimize Cardiovascular Therapy
Iris Thiele Isip-Tan
 

Recently uploaded (20)

Neuro Saphirex Cranial Brochure
Neuro Saphirex Cranial BrochureNeuro Saphirex Cranial Brochure
Neuro Saphirex Cranial Brochure
 
Telehealth Psychology Building Trust with Clients.pptx
Telehealth Psychology Building Trust with Clients.pptxTelehealth Psychology Building Trust with Clients.pptx
Telehealth Psychology Building Trust with Clients.pptx
 
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...
 
How many patients does case series should have In comparison to case reports.pdf
How many patients does case series should have In comparison to case reports.pdfHow many patients does case series should have In comparison to case reports.pdf
How many patients does case series should have In comparison to case reports.pdf
 
Demystifying-Gene-Editing-The-Promise-and-Peril-of-CRISPR.pdf
Demystifying-Gene-Editing-The-Promise-and-Peril-of-CRISPR.pdfDemystifying-Gene-Editing-The-Promise-and-Peril-of-CRISPR.pdf
Demystifying-Gene-Editing-The-Promise-and-Peril-of-CRISPR.pdf
 
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptx
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptx
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptx
 
VVIP Dehradun Girls 9719300533 Heat-bake { Dehradun } Genteel ℂall Serviℂe By...
VVIP Dehradun Girls 9719300533 Heat-bake { Dehradun } Genteel ℂall Serviℂe By...VVIP Dehradun Girls 9719300533 Heat-bake { Dehradun } Genteel ℂall Serviℂe By...
VVIP Dehradun Girls 9719300533 Heat-bake { Dehradun } Genteel ℂall Serviℂe By...
 
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
GURGAON Call Girls ❤8901183002❤ #ℂALL# #gIRLS# In GURGAON ₹,2500 Cash Payment...
 
.Metabolic.disordersYYSSSFFSSSSSSSSSSDDD
.Metabolic.disordersYYSSSFFSSSSSSSSSSDDD.Metabolic.disordersYYSSSFFSSSSSSSSSSDDD
.Metabolic.disordersYYSSSFFSSSSSSSSSSDDD
 
Myopia Management & Control Strategies.pptx
Myopia Management & Control Strategies.pptxMyopia Management & Control Strategies.pptx
Myopia Management & Control Strategies.pptx
 
HEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptxHEAT WAVE presented by priya bhojwani..pptx
HEAT WAVE presented by priya bhojwani..pptx
 
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...
 
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and BeyondEmpowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
Empowering ACOs: Leveraging Quality Management Tools for MIPS and Beyond
 
Health Education on prevention of hypertension
Health Education on prevention of hypertensionHealth Education on prevention of hypertension
Health Education on prevention of hypertension
 
CONSTRUCTION OF TEST IN MANAGEMENT .docx
CONSTRUCTION OF TEST IN MANAGEMENT .docxCONSTRUCTION OF TEST IN MANAGEMENT .docx
CONSTRUCTION OF TEST IN MANAGEMENT .docx
 
Contact ME {89011**83002} Haridwar ℂall Girls By Full Service Call Girl In Ha...
Contact ME {89011**83002} Haridwar ℂall Girls By Full Service Call Girl In Ha...Contact ME {89011**83002} Haridwar ℂall Girls By Full Service Call Girl In Ha...
Contact ME {89011**83002} Haridwar ℂall Girls By Full Service Call Girl In Ha...
 
Roti bank chennai PPT [Autosaved].pptx1
Roti bank  chennai PPT [Autosaved].pptx1Roti bank  chennai PPT [Autosaved].pptx1
Roti bank chennai PPT [Autosaved].pptx1
 
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfCHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdf
 
Surgery-Mini-OSCE-All-Past-Years-Questions-Modified.
Surgery-Mini-OSCE-All-Past-Years-Questions-Modified.Surgery-Mini-OSCE-All-Past-Years-Questions-Modified.
Surgery-Mini-OSCE-All-Past-Years-Questions-Modified.
 
Artificial Intelligence to Optimize Cardiovascular Therapy
Artificial Intelligence to Optimize Cardiovascular TherapyArtificial Intelligence to Optimize Cardiovascular Therapy
Artificial Intelligence to Optimize Cardiovascular Therapy
 

Scorpion venom

  • 2. SCORPION VENOM An insect that has elongated body a segmented, curved tail tipped with a venomous stinger. A sting can be fatal to a person who is allergic to it. The toxicity of scorpion venom varies by species. A given species' venom may contain many chemicals, some toxic to insects, toxic to mammals. Scorpion species with smaller and more slender claws generally have toxic venom. Scorpion stings are much more dangerous for infants and small children.
  • 3. PATHOPHYSIOLOGY oGrade 1: Local pain and paresthesias at the sting site. The puncture wound may not be noticeable in this grade. The "tap test" may confirm a provider's suspicion by distracting the patient and tapping on the area of the sting, causing increased pain. This does not occur other species. Care is limited to analgesia. oGrade 2: Local pain and paresthesias at the sting site as well as proximally. Recommended care again includes analgesia with optional When serious symptoms do occur, they are usually due to the Centruroides species. Because of this, a classification scale has been created to grade each envenomation by a Centruroides scorpion.
  • 4. PATHOPHYSIOLOGY o Grade 3: Grade 2 with added cranial nerve (increased oral secretions, blurry vision, rapid tongue movement, nystagmus) or skeletal neuromuscular dysfunction (flailing of the extremities and tetanus-like arching of the back). These patients require analgesia and anxiolytics as well as antivenom. o Grade 4: Unlike grade 3 envenomations where the patient will experience either cranial nerve or skeletal muscle dysfunction, grade 4 envenomations include both. This can cause hyperthermia, rhabdomyolysis, pulmonary edema, and multiple organ failures. antivenom is critical in this situation.
  • 5. SIGNS AND SYMPTOMS • Signs and symptoms at the site of the sting may include: – Pain, which can be intense – Numbness and tingling in the area the sting – Slight swelling in the area around the Most scorpion stings cause only localized signs and symptoms, such as pain and warmth at the site of the sting. Sometimes these symptoms may be quite intense, even if you don't see redness or swelling.
  • 6. SIGNS AND SYMPTOMS • Signs and symptoms related to widespread (systemic) venom effects usually occur in children who are stung and may include: – Difficulty breathing – Muscle twitching or thrashing – Unusual head, neck and eye movements – Drooling – Sweating – Nausea and vomiting – High blood pressure (hypertension) – Accelerated heart rate (tachycardia) or irregular heart beat (arrhythmia) – Restlessness or excitability or inconsolable crying (in children)
  • 7. HISTORY AND PHYSICAL EXAMINATION • Most scorpion stings cause a local inflammatory reaction and pain. • When the venom affects the sodium channels, this may manifest as seizure-like activity in the patient and obscure the clinical picture, especially when the child or infant is unable to relay an accurate history. • Intubation may be required in these patients, as motor hyperactivity of the pharyngeal muscles and uncontrolled diaphragmatic and intercostal neuromuscular activity may be seen. • These symptoms may progress quickly, causing impending airway collapse. • In the select species causing cardiopulmonary effects, tachycardia, pulmonary edema, and more importantly, cardiogenic shock may be seen. • While uncommon, local tissue necrosis in days to weeks after the initial
  • 8. TREATMENT moving the patient away from the scorpion stabilizing the patient's airway and vital signs administration of antivenin institution of symptomatic and local treatment.
  • 9. LOCAL TREATMENT Calm the patient • to lower the heart rate and blood pressure, thus limiting the spread of the venom. Use ice bags • to reduce pain and to slow the absorption of venom via vasoconstriction. • This is most effective during the first 2 hours following the sting. Administer local wound care. Apply a topical or local anesthetic agent to the wound to decrease paresthesia Administer muscle relaxants for severe muscle spasms Administer tetanus prophylaxis Administer systemic antibiotics if signs of secondary infection occur.
  • 10. LOCAL TREATMENTapplying a lymphatic-venous compression wrap 1 inch proximal to the sting site • For medical delay of secondary infection • to reduce superficial venous and lymphatic flow of the venom but not to stop the arterial flow. • Only remove this wrap when the provider is ready to administer systemic support. Immobilize the affected part in a functional position below the level of the heart
  • 11. SYSTEMIC TREATMENT Establish airway, breathing, and circulation (ie, ABCs) Monitor vital signs Use invasive monitoring for patients who are unstable and hemodynamic. Administer oxygen. Administer intravenous fluids to help prevent hypovolemia Perform intubation and institute mechanical ventilation Administer atropine to counter venom-induced parasympathomimetic effects.
  • 12. SYSTEMIC TREATMENT HYPERDYNAMIC CARDIOVASCULAR CHANGES administration of a combination of beta-blockers with sympathetic alpha- blockers is most effective in reversing this venom-induced effect. • Avoid using beta-blockers alone because this leads to an unopposed alpha-adrenergic effect. nitrates can be used for hypertension and myocardial ischemia. diuretic may be used for pulmonary edema in the absence of hypovolemia • afterload reducer, such as prazosin, nifedipine, nitroprusside, hydralazine, or angiotensin-converting enzyme inhibitors, is better.Inotropic medications, such as digitalis, have little effect, while dopamine aggravates the myocardial damage through catecholamine-like actions. pressor such as norepinephrine to correct hypotension refractory to fluid therapy.