Gonorrhea is a sexually transmitted disease caused by Neisseria gonorrhoea that mainly affects the genitals, rectum, and throat. It is estimated that 98 million new cases occur annually worldwide. Risk factors include having multiple sex partners or a new sex partner. Symptoms vary depending on the infected area but may include painful urination, increased discharge, or bleeding. It is treated with antibiotics like ceftrioxone or cefotaxime. Prevention involves safe sex practices and testing of partners.

2.  Gonorrhea is a sexually transmitted
disease caused by Neisseria gonorrhoea
that can affect both men and women,
mainly affects genitals, rectum and
throat.

3.  98 million new cases of Gonorrhea occur
annually, according to WHO estimates
 Prevalence of gonorrhoea ranges from 0-
19% in India from 2000-2009

4.  Gonorrhea of genital tract- Affects
genitals
 Gonorrhea of rectum- Affects rectum
 Gonorrhea of eyes- Affects eyes
 Gonorrhea of throat- Affects throat
 Gonorrhea of joints- Affects joints

5.  Younger age
 New sex partner
 Persons with multiple sex partners
 Previous gonorrhoea diagnosis
 Persons with other sexually transmitted
diseases

6.  It is caused by Neisseria gonorrhoea
 It is transmitted through sexual contact

9. Genital tract- men-
o Painful when urination
o Pus like discharge from tip of penis
Genital tract- women-
 Increased vaginal discharge
 Painful urination
 Painful intercourse
 Vaginal bleeding between periods
 Abdominal/ pelvic pain

11. Rectum
 Itching
 Pus like discharge from rectum
 Bleeding
Eyes
 Eye pain
 Sensitivity of light
 Pus like discharge from one/ both eyes
Throat
 Sore throat
 Swollen lymph nodes in the neck
Joints
 Red, swollen and painful joints

12.  Infertility in men and women
 Septic Arthralgia
 Blindness to babies of infected mothers
 Epididymitis
 Prostatitis
 Inguinal lymphadenopathy
 Urethral stricture
 Pelvic inflammatory disease

13.  Gram staining
 Culture sensitivity test
 Enzyme immune assay
 DNA probe techniques
 Nucleic acid amplification techniques

15.  Counselling on safe sex practices

17. Drug Category Mode of action Dose Adverse affects
Ceftrioxone Cephalosporin It inhibits
bacterial cell
wall synthesis
250mg-IM-
once
 Injection site reactions
 Eosinophilia
 Thrombocytosis
 Diarrhoea
 Transaminitis
Cefotaxime Cephalosporin It inhibits
bacterial cell
wall synthesis
0.5g-IM-once  Injection site reactions
 Eosinophilia
 Pseudomembranous colitis
 Nephrotoxicity
 Hepatotoxicity
Azithromycin Macrolides It inhibits
bacterial protein
synthesis
1g-PO-once  Diarrhoea
 Abdominal pain
 Cramping
 Vaginitis
 Dyspepsia
Erythromycin Macrolides It inhibits
bacterial protein
synthesis
0.5% ointment  Burning in eyes
 Stinging in eyes
 Redness in eyes
 Irritation in eyes
 Temporary blurred vision

18.  https://www.ncbi.nlm.nih.gov/pmc/articles/P
MC5839552/
 https://www.ncbi.nlm.nih.gov/pmc/articles/P
MC5735573/
 https://www.sciencedirect.com/science/articl
e/pii/S1876034117301326?via%3Dihub
 https://www.ncbi.nlm.nih.gov/pmc/articles/P
MC4874098/
 http://www.ijmm.org/article.asp?issn=0255-
0857;year=2015;volume=33;issue=1;spage=
39;epage=42;aulast=Bharara