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Gangrene
By
Amira Essam
Medical student
-source-
Short text book of pathology Dr Mohamed danish
Pathology
• The clinical condition results from necrosis or putrefaction of tissue
due to infection .
Necrosis putrefaction infection gangrene
causes
Arterial
obstruction
infection trauma Physical agents
Due to :
• Thrombosis
• Embolus
• Diabetes
• Burger’s disease
• Raynaud’s disease
In
• Boils
• carbuncles
In
• Crush injuries
• Pressure sores
With
• Burns
• Frostbite
• chemicals
Types
• Wet gangrene
• Dry gangrene
• Gas gangrene
• Appears moist , results from severe bacterial infection superimposed
on necrosis. Found on internal organs and exposed parts
• Appears dry ,wrinkled and discolored , results from gradual
obstruction of blood supply. Found on exposed parts.
• Wet gangrene + gas formation , Found on exposed parts.
Types
wet dry gas
Smell foul No smell foul
Edema + + +
Black color + + -
Line of discrimination no Yes between living and
dead cells
no
Gas bubbles no no Yes with crepitus
Treatment
• Treatment of predisposing factors.
• Amputation : surgical removal of gangrenous part to
prevent spreading.
Thanks

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Gangrene

  • 1. Gangrene By Amira Essam Medical student -source- Short text book of pathology Dr Mohamed danish
  • 2. Pathology • The clinical condition results from necrosis or putrefaction of tissue due to infection . Necrosis putrefaction infection gangrene
  • 3. causes Arterial obstruction infection trauma Physical agents Due to : • Thrombosis • Embolus • Diabetes • Burger’s disease • Raynaud’s disease In • Boils • carbuncles In • Crush injuries • Pressure sores With • Burns • Frostbite • chemicals
  • 4. Types • Wet gangrene • Dry gangrene • Gas gangrene • Appears moist , results from severe bacterial infection superimposed on necrosis. Found on internal organs and exposed parts • Appears dry ,wrinkled and discolored , results from gradual obstruction of blood supply. Found on exposed parts. • Wet gangrene + gas formation , Found on exposed parts.
  • 5. Types wet dry gas Smell foul No smell foul Edema + + + Black color + + - Line of discrimination no Yes between living and dead cells no Gas bubbles no no Yes with crepitus
  • 6. Treatment • Treatment of predisposing factors. • Amputation : surgical removal of gangrenous part to prevent spreading.