2. Pathology
• The clinical condition results from necrosis or putrefaction of tissue
due to infection .
Necrosis putrefaction infection gangrene
3. causes
Arterial
obstruction
infection trauma Physical agents
Due to :
• Thrombosis
• Embolus
• Diabetes
• Burger’s disease
• Raynaud’s disease
In
• Boils
• carbuncles
In
• Crush injuries
• Pressure sores
With
• Burns
• Frostbite
• chemicals
4. Types
• Wet gangrene
• Dry gangrene
• Gas gangrene
• Appears moist , results from severe bacterial infection superimposed
on necrosis. Found on internal organs and exposed parts
• Appears dry ,wrinkled and discolored , results from gradual
obstruction of blood supply. Found on exposed parts.
• Wet gangrene + gas formation , Found on exposed parts.
5. Types
wet dry gas
Smell foul No smell foul
Edema + + +
Black color + + -
Line of discrimination no Yes between living and
dead cells
no
Gas bubbles no no Yes with crepitus
6. Treatment
• Treatment of predisposing factors.
• Amputation : surgical removal of gangrenous part to
prevent spreading.