There are a lot of reasons to take a closer look at Sweden. One of them is that it is a country of great natural beauty and wilderness. But Sweden is also at the front line of global issues such as equality, human rights and sustainability. Swedes are some of the world's fastest people at adapting to new trends and ideas, and, it seems, are constantly on the cusp of a groundbreaking innovation.
Written by two former Swedish expats, Sweden-Up North, Down to Earth gives an overall view of Sweden as it is today. It presents regular Swedes and astonishing Swedes, supercars and indie rock bands, vampires and royalty.
There are a lot of reasons to take a closer look at Sweden. One of them is that it is a country of great natural beauty and wilderness. But Sweden is also at the front line of global issues such as equality, human rights and sustainability. Swedes are some of the world's fastest people at adapting to new trends and ideas, and, it seems, are constantly on the cusp of a groundbreaking innovation.
Written by two former Swedish expats, Sweden-Up North, Down to Earth gives an overall view of Sweden as it is today. It presents regular Swedes and astonishing Swedes, supercars and indie rock bands, vampires and royalty.
Wildlife Of Greenland
The wildlife of Greenland is very different. Familiar mammals in Greenland include the Arctic hare, collared lemming, ermine and Arctic fox. Reindeer hunting is of considerable cultural importance to the people of Greenland. Visit: http://touringgreenland.com/City_tours_category
Sleep is a crucial health issue - but it is often ignored by both individuals and the medical community. Sleep has been shown to substantially impact almost every major health condition including Diabetes, Cancer, Obesity, Heart Disease, and Mental Health. It's time for sleep to take it's rightful place in keeping us health. This presentation gives some of the cold, hard facts behind why sleep is such a silent killer.
Wildlife Of Greenland
The wildlife of Greenland is very different. Familiar mammals in Greenland include the Arctic hare, collared lemming, ermine and Arctic fox. Reindeer hunting is of considerable cultural importance to the people of Greenland. Visit: http://touringgreenland.com/City_tours_category
Sleep is a crucial health issue - but it is often ignored by both individuals and the medical community. Sleep has been shown to substantially impact almost every major health condition including Diabetes, Cancer, Obesity, Heart Disease, and Mental Health. It's time for sleep to take it's rightful place in keeping us health. This presentation gives some of the cold, hard facts behind why sleep is such a silent killer.
Essential nutrients and some risk factors based on poor nutrition. This is an updated version from a previously uploaded presentation.
So maybe delete the old one..consider this a work in progress :)
Protein doesn't just mean steak! Nuts, beans/legumes, soy, and other plant based proteins can adequately meet a person's protein needs while reducing one's carbon footprint and improving health. In this workshop, discover how to incorporate more plant proteins into your diet with recipes using ingredients like lentils, chickpeas, almonds, and seitan.
This powerpoint provides "Choose My Plate" informative slides and student activities. Note- The information in this lesson will require multiple days to cover. Please review the materials in advance and decide which activities you would like to include. Computer lab or cart access is required for many of the projects and activities.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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2. Why do we need fuel for our bodies? For energy to perform throughout the day Achieve or maintain an optimal weight
3. Where do we get our Fuel? Six Basic Nutrients Carbohydrates Protein Fat Vitamins Minerals Water
4. Carbohydrates Provide energy for the muscles Comes from starches and sugars in the form of glycogen. Helps digestion and the control of fat and cholesterol
5. Protein Essential for developing new tissue Maintains existing tissue, including muscles, red blood cells, and hair Produces essential enzymes, antibodies and hormones Control the water level inside and outside the cells
6. Fat Primary source of stored energy that is used when the body is resting and long-term aerobic activity Saturated fat (meat, butter) contributes to cardiovascular disease and cancer Unsaturated fat (olive oil, canola oil) is healthier
7. Vitamins Regulate metabolic reactions within the body Types of Vitamins A- helps the eyes work correctly A and C- needed for the immune system B- help cells burn energy and the nervous system D- help calcium and phosphorus go from the food you eat to your bloodstream
8. Minerals Help form structures in the body and regulate body processes. Types of Minerals: Calcium, Phosphorus and Magnesium- help keep bones strong Fluoride- strengthens teeth Iron- essential in oxygen transport Sodium and Potassium- vital in controlling blood volume Zinc- helps derive energy from fuel Iodine- helps control the rate energy is used
9. Water Temperature control through sweating Carries nutrients to cells Removes waste from cells Important constituent of muscle and in processes inside cells Constitutes 60 to 70 percent of the body’s weight
11. Food Groups from the Food Guide Pyramid Grains Vegetables Fruits Milk and Dairy Proteins Oils and Fats
12. Eat 6-11 servings of grains a day based on a 2,000 calorie diet Make half of your grains whole grain Grains include: cereals, rice, bread and pasta One serving = 1 oz = one slice of bread
13. Benefits of Grains Reduce the risk of heart disease Grains contain fiber which help reduce constipation Whole grains help with weight management Provide many nutrients that are vital for the health and maintenance of our bodies.
14. Eat 3-5 servings of vegetables a day based on a 2,00 calorie diet Try to vary your veggies (Eat veggies of different colors) Vegetables include: Broccoli, Carrots, Corn, Asparagus, Spinach, Cauliflower, Potatoes One serving of vegetables= ½ cup cooked or chopped raw veggies or 1 cup of raw leafy vegetables or ½ cup of vegetable juice
15. Benefits of vegetables Reduces the risk of heart disease, heart attack and stroke, obesity and type 2 diabetes Helps protect against cancers May lower blood pressure Helps decrease bone loss May reduce the risk of developing kidney stones
16. Eat 2-4 servings of fruits a day based on a 2,000 calorie diet Fruits include: grapes, watermelon, oranges bananas, apples, pears, strawberries, pineapple, peaches One serving of fruits = 1 medium apple, orange or banana or ¼ cup of dried fruit or ¾ cups of fruit juice or ½ cup of chopped, cooked or canned fruit
17. Benefits of fruits Reduces the risk of heart disease, heart attack and stroke, obesity and type 2 diabetes Helps protect against cancers May lower blood pressure Helps decrease bone loss May reduce the risk of developing kidney stones
18. Eat 2-3 servings of dairy products a day based on a 2,000 calorie diet Dairy products include: Milk, yogurt, cheese One serving of dairy = 1 cup of milk or yogurt, 1.5 oz of natural cheese, 2 oz of processed cheese (American cheese) It’s best to choose dairy products that are either fat-free or low-fat If you can’t consume dairy, get your daily servings from lactose-free products or other sources of calcium from fortified foods or beverages
19. Benefits of Dairy Products Improves bone health Reduces Osteoporosis Reduces the risk of cardiovascular disease, type 2 diabetes Can lower blood pressure in adults
20. Eat 2-3 servings of protein products a day based on a 2,000 calorie diet Its best to vary your protein and choose low-fat or lean meats Proteins include: Meat, Fish, Poultry (chicken), Eggs, Nuts and Beans One serving of protein = 1 egg, or ½ cup or dried cooked beans, or 2 tbsp of peanut butter, or 1/3 cup of nuts Meat, fish and poultry should be cooked in total ounces per day (2-3 oz cooked)
21. Benefits of Protein Foods Supply many nutrients such as: protein, B vitamins, Vitamin E, Iron, Zinc and Magnesium Proteins are the building blocks for, bones, skin, blood, muscles and cartilage B Vitamins help the body release energy and plays a role in the function of the nervous system and helps build tissue Iron is used to carry oxygen to the blood Magnesium is used for building bones and releasing energy from the muscles Zinc helps the immune system function properly
22. Fats and Oils Fats and Oils should be used sparingly Fats and Oils is found in salad dressings, cream cheese, butter, margarine, shortening, sugars, soft drinks, fruit drinks, candies, and sweet snack foods Limit these foods because they provide calories and few vitamins and minerals
32. Physical Activity Can produce long-term health benefits Increase self-esteem Have stronger bones and muscles Stay at or get a healthier weight Increase your chances of living longer
34. Physical Activity Young Children (ages 2-5) should be active a number of minutes several times a day Children and Adolescents (ages 6-17) should do 60 minutes or more of physical activity each day Adults (ages 18+) should be active 5 or more hours each week spreading out over at the least 3 days a week
35. Tips for increasing physical activity Get the whole family involved Join groups in your neighborhood Take the steps instead of the escalator or elevator Replace breaks at work with a brisk walk Do active activities that are fun for YOU!