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Introduction
 Uterine lining implants itself to
other organs in the pelvic
region. Ex.. Ovaries, bladder,
fallopian tubes
 Appears as cysts and adhesions
 Causes a great deal of menstrual
pain
 Affects women of the
reproductive age
 Remains a “hidden” disease until
other problems arise
possible locations of endometriosis
Symptoms
 Pelvic Pain (acute or chronic)
 Dyspareunia (painful intercourse)
 Painful bowel movements
 Premenstrual staining and abnormal bleeding
 Difficult urination and/or blood present in the
urine
 Infertility
Some Theoretical Causes
 Genetic, “runs in the family”
 Retrograde menstruation
 Problems in the immune system
 Estrogen
Effects on the Body
 Linked to infertility
 Miscarriages
 Loss of reproductive organs (hysterectomy)
 Psychologically damaging
 Chronic pain
Methods of Diagnosis
 Most cases diagnosed because of other complication(s)
 Laparoscopy is best detector and treatment option
Some Classifications
 Mild- Rare, scattered lesions, no scarring
 Moderate- Minimal adhesions and superficial
implants
 Severe- Reproductive organs are bound down by
growths, bladder and/or bowel may also become
affected
Stages
Photos
 A small adhesion on an
ovary about to be
removed surgically
Photos
 Endometriosis growing
on the ovary and
fallopian tube
Photos
 Severe endometriosis
on the back of the
uterus causing
adhesions of the bowel
and pelvic organs
Treatment Options- Surgical
 Laparoscopy- method of choice
 Conservative surgery
 Hysterectomy
Treatment Options- Non surgical
 Gonadotropin-releasing hormone agonists,
Danazol, Gestrinone
 All acyclic, some high androgen, others high
progesterone, all low estrogen
 Negative side effects such as accelerated bone loss,
weight gain, nausea, breakthrough bleeding
 Pain killers (aspirin, morphine, and codeine)
Statistics
 6-58% of infertile women have endometriosis
 30-50% of women with endometriosis are infertile (twice
the rate of the general population)
 Up to 22% of women have no symptoms
 30-50% of women with this disease have had miscarriages
 Between 1965-1984 ~2 million US women between ages 25-
54 diagnosed received a hysterectomy
 Painful disease: 66% of women experience chronic pain
 1 out of 10 women from menarche to menopause can be
expected to have some degree of endometriosis EXCEPT
women with a sister, mother, or daughter already
diagnosed, then incidences double to 1 out of 5
Conclusion
 No cure
 Combination therapy involving surgery, hormones,
and (if needed) assisted reproduction

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Endometriosis

  • 1.
  • 2. Introduction  Uterine lining implants itself to other organs in the pelvic region. Ex.. Ovaries, bladder, fallopian tubes  Appears as cysts and adhesions  Causes a great deal of menstrual pain  Affects women of the reproductive age  Remains a “hidden” disease until other problems arise
  • 3. possible locations of endometriosis
  • 4. Symptoms  Pelvic Pain (acute or chronic)  Dyspareunia (painful intercourse)  Painful bowel movements  Premenstrual staining and abnormal bleeding  Difficult urination and/or blood present in the urine  Infertility
  • 5. Some Theoretical Causes  Genetic, “runs in the family”  Retrograde menstruation  Problems in the immune system  Estrogen
  • 6. Effects on the Body  Linked to infertility  Miscarriages  Loss of reproductive organs (hysterectomy)  Psychologically damaging  Chronic pain
  • 7. Methods of Diagnosis  Most cases diagnosed because of other complication(s)  Laparoscopy is best detector and treatment option
  • 8. Some Classifications  Mild- Rare, scattered lesions, no scarring  Moderate- Minimal adhesions and superficial implants  Severe- Reproductive organs are bound down by growths, bladder and/or bowel may also become affected
  • 10. Photos  A small adhesion on an ovary about to be removed surgically
  • 11. Photos  Endometriosis growing on the ovary and fallopian tube
  • 12. Photos  Severe endometriosis on the back of the uterus causing adhesions of the bowel and pelvic organs
  • 13. Treatment Options- Surgical  Laparoscopy- method of choice  Conservative surgery  Hysterectomy
  • 14.
  • 15. Treatment Options- Non surgical  Gonadotropin-releasing hormone agonists, Danazol, Gestrinone  All acyclic, some high androgen, others high progesterone, all low estrogen  Negative side effects such as accelerated bone loss, weight gain, nausea, breakthrough bleeding  Pain killers (aspirin, morphine, and codeine)
  • 16. Statistics  6-58% of infertile women have endometriosis  30-50% of women with endometriosis are infertile (twice the rate of the general population)  Up to 22% of women have no symptoms  30-50% of women with this disease have had miscarriages  Between 1965-1984 ~2 million US women between ages 25- 54 diagnosed received a hysterectomy  Painful disease: 66% of women experience chronic pain  1 out of 10 women from menarche to menopause can be expected to have some degree of endometriosis EXCEPT women with a sister, mother, or daughter already diagnosed, then incidences double to 1 out of 5
  • 17. Conclusion  No cure  Combination therapy involving surgery, hormones, and (if needed) assisted reproduction