Explains the inflammatory process of endometrium,its causes and its two clinical variants as acute and chronic endometritis.
Describes the pathology of its two types with histologic perspective.
Endometritis is caused by an infection in the uterus. It can be due to chlamydia, gonorrhea, tuberculosis, or a mix of normal vaginal bacteria. It is more likely to occur after miscarriage or childbirth. It is also more common after a long labor or C-section.
Bartholin’s Gland
Function :
The production of mucoid secretion that lubricates the
distal end of the vagina during intercourse.
The glands become active after menarche and are non
palpable.
Bartholinitis
Causative agent:
Gonococcus
Streptococcus
Staphylococcus
E. coli
End result :
Complete resolution
Recurrence
Abscess
Cyst formation
Clinical features :
Local pain discomfort.
Difficulty in walking / sitting.
Examination :
Tenderness
Induration of post half of vagina.
Secretion coming out from the duct when pressed.
Treatment
Local :
Systemic:
Ampicillin 500 mg TDS
Bartholin’s Abscess
End result of acute Bartholinitis.
Clinical features:
Severe local pain and discomfort.
Difficult / painful walking and sitting.
On examination:
Unilateral tender swelling.
Oedomatous red overlying skin.
Treatment:
Rest.
Sitz bath.
Systemic antibiotic Ampicillin 500 mg.
Drainage of abscess.
Bartholin’s cyst
The content is colourless glairy liquid.
C/f :
Small cyst : usually unnoticed.
Larger cyst : Local discomfort and dyspareunia.
Examination:
Unilateral swelling on post half of labia majora.
Projection on vulval cleft into S-shape.
Overlying skin is shiny and thin.
Cyst remains non tender and fluctuant.
Treatment:
Marsupilisation.
Endometritis is caused by an infection in the uterus. It can be due to chlamydia, gonorrhea, tuberculosis, or a mix of normal vaginal bacteria. It is more likely to occur after miscarriage or childbirth. It is also more common after a long labor or C-section.
Bartholin’s Gland
Function :
The production of mucoid secretion that lubricates the
distal end of the vagina during intercourse.
The glands become active after menarche and are non
palpable.
Bartholinitis
Causative agent:
Gonococcus
Streptococcus
Staphylococcus
E. coli
End result :
Complete resolution
Recurrence
Abscess
Cyst formation
Clinical features :
Local pain discomfort.
Difficulty in walking / sitting.
Examination :
Tenderness
Induration of post half of vagina.
Secretion coming out from the duct when pressed.
Treatment
Local :
Systemic:
Ampicillin 500 mg TDS
Bartholin’s Abscess
End result of acute Bartholinitis.
Clinical features:
Severe local pain and discomfort.
Difficult / painful walking and sitting.
On examination:
Unilateral tender swelling.
Oedomatous red overlying skin.
Treatment:
Rest.
Sitz bath.
Systemic antibiotic Ampicillin 500 mg.
Drainage of abscess.
Bartholin’s cyst
The content is colourless glairy liquid.
C/f :
Small cyst : usually unnoticed.
Larger cyst : Local discomfort and dyspareunia.
Examination:
Unilateral swelling on post half of labia majora.
Projection on vulval cleft into S-shape.
Overlying skin is shiny and thin.
Cyst remains non tender and fluctuant.
Treatment:
Marsupilisation.
Cervical Erosion
Dr. Yashika
Definition
Cervical erosion is a condition where the squamous epithelium of the ectocervix is replaced by columnar epithelium which is continuous with endocervix.
Aetiology
Congenital
Acquired
Clinical features
Symptoms :
Vaginal discharge
Contact bleeding
Associated cervicitis
SIGNS :
Diagnosis
Ectropion
Early carcinoma
Primary Lesion (Chancre)
Tubercular ulcer
Management
Pregnancy
Pill user
Persistent ectopy
this lecture involves full, simple and easy description of cervicitis
including acute and chronic cervicitis and the major causes for it as Neisseria gonorrhea and chlamydia trachomatous
also chronic infection and ectopy
Cervical Erosion
Dr. Yashika
Definition
Cervical erosion is a condition where the squamous epithelium of the ectocervix is replaced by columnar epithelium which is continuous with endocervix.
Aetiology
Congenital
Acquired
Clinical features
Symptoms :
Vaginal discharge
Contact bleeding
Associated cervicitis
SIGNS :
Diagnosis
Ectropion
Early carcinoma
Primary Lesion (Chancre)
Tubercular ulcer
Management
Pregnancy
Pill user
Persistent ectopy
this lecture involves full, simple and easy description of cervicitis
including acute and chronic cervicitis and the major causes for it as Neisseria gonorrhea and chlamydia trachomatous
also chronic infection and ectopy
En el marco del curso Infecciones en el embarazo y puerperio, desarrollado por el programa SOS Telemedicina, se presenta la conferencia de la Dra. Sofía Crocco B. sobre Endometritis puerperal.
Encuentra todo lo k necesitas a cerca de las vulvovaginitis: vaginosis bacteriana y vaginitis que incluye tricomoniasis y candidiasis. Todo lo anterior con su respectivo tratamiento en Colombia
This presentation touches briefly on the vaginal discharges, both physiological and pathological, approach to management, and a brief touch on pelvic inflammatory disease.
Topic: Polycystic Ovarian Syndrome.
Etiology of the PCOS, Risk factors,clinical features, diagnosis, treatment and complications of the PCOS. The diagnosis is discussed according to clinical criteria. The investigations are discussed in details as well.
Topic of presentation: Lymphoma. Pathology of Lymphoma, stages of Lymphoma, types of Lymphoma. Hodgkin and Non-Hodgkin lymphoma are discussed along with their sub types clinical features, diagnosis, treatment and prognosis.
Topic : MENINGITIS
Discussion on meningitis; it's etiology, clinical features, diagnosis,treatment and prevention.
Etiology on the basis of causative agents is described. Clinical manifestations are listed along with methods of diagnosis in detail. The treatment is discussed according to the causative agent. How meningitis can be prevented will also be discussed . Hope this presentation will help you.
Topic of presentation: Amenorrhea. Content includes: Introduction, Etiology, signs and symptoms, classification, diagnosis and management with treatment. How it can be prevented. Both the types: Primary and secondary are discussed.
This presentation discusses COVID-19. It covers etiology, epidemiology, pathophysiology, clinical features, diagnosis, clinical management and treatment of COVID-19. It also discusses the effects of COVID-19 on pregnancy,how it manifests and how it is diagnosed and how it is managed. Hope this will help you.
Presentation Topic: Endometriosis. Discuss in detail the endometriosis . What is it? What is the etiology, clinical features, how can you diagnose and what is it's treatment as well as management. You'll find everything in this presentation along with pictures and illustrations.
Topic: Skull Fractures. The types of skull fractures, their etiologies,signs and symptoms, clinical presentation, radiologic diagnosis and treatment. We'll also discuss the complications of skull fractures.
Acute Abdomen. What is it and what are various causes of acute abdomen. We'll learn to evaluate acute abdomen by history taking and giving emphasize on location of pain, intensity, duration, aggravating and relieving factors of the pain. The important signs are discussed in the physical examination. Investigations are discussed as well as or the urgent indications for the action.
This presentation on the topic of Mumps. What is the etilogy,how does it spread and what is the classification of mumps. We'll discuss the clinical manifestations along with treatment and prevention of this infectious disease of the children and adults.
What is scabies? What is the cause of scabies? What is the pathogenesis of scabies? What are the types of scabies? What is the treatment of scabies? Let's discuss scabies in detail. The disease is spread by an itch mite. We'll discuss about it's transmission from human to human. How does it affects the skin and causes itching of the skin. The treatment and management is discussed as well. Hope this presentation will help you out.
This presentation is about Hyperemesis Gravidarum. What is it and what are the causes. How you'll diagnose and differentiate it from other disorders. We'll learn about it's management as well as termination of pregnancy.
Chromosomal Disorders. The types of chromosomal disorders: structural, deletion or addition. Down's syndrome, Turner's syndrome, Klinefelter's syndrome, Patau syndrome. Hope this presentation will help you.
This presentation includes the important clinical signs of the diseases. This includes physical signs and diagnostic signs which are observed on x-ray and ultrasound.
What is COPD, what causes COPD? What is the pathophysiology?How can we diagnose COPD. What is it's classification depending on severity. How can we diagnose COPD clinically as well as under microscope.How can we treat and manage COPD with the help of medicine as well as socially. Let's discuss.
Topic of discussion: Urinary Tract Infections,their etiologies. The organisms responsible for the infection of the urinary tract as well as the clinical approach to the treatment of Urinary Tract Infections (UTIs).
This presentation is about Medical importance of Enzymes and their role in clinical medicine. The types of Enzymes are mentioned along with their normal roles and in pathologies. The measurements of enzyme levels are given as well as fluctuations in their levels in the presence of pathology. Hope this will help you.
Skull fractures are discussed with their types briefly. The treatments of the fractures are discussed as well depending on the age of the patient if patient is adult or a child. The CT Scans are also given in order to better explain and help you in understanding.
Here we'll discuss the Memory Disorders and their types. We'll learn about 3 types of memories. We'll discuss Amnesia and the types of amnesia as well as the various other pathologies related to memory. Hope this will help you all
We'll discuss the treatment of Schizophrenia which includes both pharmacological and psychological intervention. The side effects of antipsychotics are also mentioned related to Central nervous system, cardiovascular system, anticholinergic and metabolism. The psychological intervention is discussed including CBT. The duration of the CBT. The social aspect is also discussed that how patient should be helped by the community.
This PPT discusses the Mood Disorders. The Major Depressive Disorder as well as Bipolar Disorder with it's types. It throws light on the treatment of the disorders as well. The medical conditions associated with these disorders are also discussed. Hope these slides will help you.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
2. ENDOMETRIUM
It is the lining of uterus.it consists of columnar
epithelium and stroma.it has two layers;
1)functional built after end of menstruation during the
first part of the previous menstrual cycle.It sheds
during menstruation.
2)basal layer is not shed during menstrual cycle and
functional layer develops from it.
3. It is inflammation of the lining of the uterus.
Commonly occurs after giving birth or also in
non-pregnant women.
In addition to endometrium, inflammation
may involve myometrium and occasionally
parametrium.
4. Causes of Endometritis
Endometritis is caused by infection in the uterus.It can be due
to;
-Chlamydia
-Tuberculosis
-Gonorrhea
-Mix. of normal vaginal bacteria.
It is most likely to occur after miscarriage or childbirth or after
C-section.
It can be transmitted through following medical procedures;
-Hysteroscopy
-Placement of an Intra Uterine Device(IUD)
-Uterine scrapping
5. Symptoms
Dysmenorrhea
Dyspareunia
Abnormal vaginal discharge
-increased amount
-unusual color,consistency,color
Discomfort with bowel movement(including
constipation).
Fever(range from 37.8 to 40C)
General discomfort, uneasiness, or ill
feeling(malaise).
Pain in lower abdomen or pelvic region.
Pain is typically chronic and crampy.
Infertility.
6. Acute endometritis
It is characterized by infection.The organisms
most often isolated are because of compromised
abortions, delivery,medical instrumentation and
retention of placental fragments.
Histologically; Neutrophilic infiltration of the
endometrial tissue is present during the acute
endometritis.
Clinical presentation include typical high fever
and purulent vaginal discharge.
7. Menstruation after acute endometritis is
excessive.
Most often caused by Staphylococci,
Streptococci or N.gonorrheae.
8. Chronic endometritis
Characterized by the presence of the plasma cells in
the stroma.
Lymphocytes, eosinophills and even lymphoid
follicles can be seen but in the absence of plasma
cells are not enough for a histologic diagnosis.
The most common organisms are;
-Neisseria gonorrheae
-Chlamydia
-Streptococcus Agalactiae
-Tuberculosis
-Mycoplasma
-Various viruses
9. Patients suffering from chronic endometritis
may have an underlying cancer of the cervix or
the endometrium.
