This document provides an overview and introduction to using Embase. It discusses the webinar controls, contents that will be covered which include tools, why Embase is used and who the typical users are, and guiding users through initial investigations, building search strategies, and refining results. Support tools are highlighted such as training webinars, search guides, videos, and a newsletter. Methods for building and combining searches, as well as refining results through limits, filters, and saving searches are covered. Finally, there is a reminder about the next introductory webinar and information on accessing the slides and recording.
Els nuigalway-embase-training-gm-slidespdfrosie.dunne
The document provides an agenda for an Embase introduction and workshop. It includes an overview of Embase indexing and content, a demonstration of searching Embase using the case of "atrial fibrillation", and exploring Embase search features like Emtree terms, filters, and result visualization. It also describes Embase's comprehensive coverage of biomedical literature, controlled vocabulary, and focus on drug safety monitoring and medical devices.
Learn how to use Embase for all your biomedical searches.
- Which workflows are supported by Embase and why
- An overview of content and indexing compared to Medline
- A demo in Embase of some introductory searches
- Answers to the most frequently asked questions by new users
- Where to find materials to support trainers
Power Point Presentation By Patient Counseling Team, Alexandria, Egypt. Presented in February 2009. Divided in four parts. This is part 1.
For comments:
http://www.facebook.com/home.php?#/group.php?gid=62233441130
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This document provides guidance on how to effectively search the literature. It discusses defining a topic and research question, choosing appropriate databases and search terms, developing a search strategy using Boolean operators and medical subject headings (MeSH), applying filters to refine results, and saving searches and setting up email alerts. The goal is to conduct a methodical search that is focused, systematic, and identifies all relevant published literature on a given topic.
Embase webinar pico search strategies as of 042115v3Ann-Marie Roche
This document describes how to construct a PICO search strategy to answer clinical questions using Embase. It explains that PICO search strategies are comprised of separate search strings for the patient population (P), intervention (I), and study type. It provides examples of search strings for common study types like randomized controlled trials, cohort studies, and systematic reviews. The document demonstrates how to build a prognosis PICO search strategy step-by-step, including combining the P, I, and study type search strings with filters and limits. The goal is to retrieve the most relevant evidence while excluding irrelevant publication types and animal studies.
This document provides guidance on developing a systematic and comprehensive search strategy for systematic reviews. It explains that a systematic search strategy is essential to capture all relevant studies on a topic. The strategy should include synonyms for key concepts, Boolean operators to combine terms, and subject headings from different databases. It provides an example of developing a search strategy based on turning a research question into PICO components and combining population, intervention, comparison, and outcome terms. The search strategy example spans multiple slides and databases to model a comprehensive approach.
Els nuigalway-embase-training-gm-slidespdfrosie.dunne
The document provides an agenda for an Embase introduction and workshop. It includes an overview of Embase indexing and content, a demonstration of searching Embase using the case of "atrial fibrillation", and exploring Embase search features like Emtree terms, filters, and result visualization. It also describes Embase's comprehensive coverage of biomedical literature, controlled vocabulary, and focus on drug safety monitoring and medical devices.
Learn how to use Embase for all your biomedical searches.
- Which workflows are supported by Embase and why
- An overview of content and indexing compared to Medline
- A demo in Embase of some introductory searches
- Answers to the most frequently asked questions by new users
- Where to find materials to support trainers
Power Point Presentation By Patient Counseling Team, Alexandria, Egypt. Presented in February 2009. Divided in four parts. This is part 1.
For comments:
http://www.facebook.com/home.php?#/group.php?gid=62233441130
you can post on the wall, or email the group admins.
This document provides guidance on how to effectively search the literature. It discusses defining a topic and research question, choosing appropriate databases and search terms, developing a search strategy using Boolean operators and medical subject headings (MeSH), applying filters to refine results, and saving searches and setting up email alerts. The goal is to conduct a methodical search that is focused, systematic, and identifies all relevant published literature on a given topic.
Embase webinar pico search strategies as of 042115v3Ann-Marie Roche
This document describes how to construct a PICO search strategy to answer clinical questions using Embase. It explains that PICO search strategies are comprised of separate search strings for the patient population (P), intervention (I), and study type. It provides examples of search strings for common study types like randomized controlled trials, cohort studies, and systematic reviews. The document demonstrates how to build a prognosis PICO search strategy step-by-step, including combining the P, I, and study type search strings with filters and limits. The goal is to retrieve the most relevant evidence while excluding irrelevant publication types and animal studies.
This document provides guidance on developing a systematic and comprehensive search strategy for systematic reviews. It explains that a systematic search strategy is essential to capture all relevant studies on a topic. The strategy should include synonyms for key concepts, Boolean operators to combine terms, and subject headings from different databases. It provides an example of developing a search strategy based on turning a research question into PICO components and combining population, intervention, comparison, and outcome terms. The search strategy example spans multiple slides and databases to model a comprehensive approach.
This document provides guidance on searching the medical literature. It discusses four categories of information resources, criteria for selecting resources, and five databases for finding primary studies. It outlines how to develop a search strategy, including turning a question into search concepts and keywords. It also covers running searches, applying screening criteria to search results, and synthesizing findings. The goal is to perform a systematic, explicit and reproducible search of the biomedical literature.
How to do a Literature search for your research and scientific publication BhaskarBorgohain4
Dr. Bhaskar Borgohain discusses strategies for conducting an effective literature search. He emphasizes defining a clear research question, brainstorming keywords, using appropriate search techniques like Boolean operators and filters, and keeping detailed records of the search process. Maintaining a search diary and using a citation manager are important for reproducing and organizing search results.
This document provides guidance on conducting an effective literature search, including how to formulate a research question, identify relevant keywords and concepts, consider appropriate levels of evidence, develop a search strategy using the PICO framework, use Boolean operators and subject headings, search appropriate databases and tracks additional relevant sources. It emphasizes breaking down the research question, using both controlled vocabulary and keyword searching across multiple databases, and adjusting the search as needed based on results.
The document discusses important considerations for developing an effective search strategy for systematic reviews, including:
1) Selecting appropriate databases and other sources based on the topic; searching MEDLINE, EMBASE, and CENTRAL at minimum.
2) Developing a focused research question to guide the search, listing relevant synonyms for participants and interventions.
3) Using controlled vocabulary and keywords, taking advantage of features like truncation, Boolean operators, and proximity searching to construct an optimized search string.
This document provides guidance on conducting an effective literature search to answer a research question in physiotherapy. It outlines the importance of developing a well-formulated question and considering the desired level of evidence. The PICO framework is introduced to break down the question into relevant concepts. Useful search techniques like Boolean operators, subject headings, limits and expanding/narrowing the search are described. Key databases for physiotherapy evidence are highlighted, including PEDro, Cochrane Library and BMJ Best Practice.
The document discusses conducting a systematic literature search to minimize bias. It describes searching multiple databases and sources in a thorough, objective and reproducible manner. Key steps include refining the clinical question, developing a search strategy using Boolean logic and Medical Subject Headings (MeSH) terms, searching bibliographic databases like PubMed and the Cochrane Library, and documenting the search strategy.
This document provides instructions for searching PsycBITE, a free database containing citations and summaries of research on psychological problems resulting from acquired brain impairment. It describes PsycBITE's contents and sources, how to access it through the La Trobe University Library website, tips for searching like using keywords and Boolean operators, an example search on exercise and depression in dementia, and how search results are rated for methodological quality. It also explains how to find full text and provides additional help resources.
The document provides an overview of how to find empirical evidence for clinical research projects, outlining key strategies and resources for developing effective search techniques and evaluating different levels of evidence, from systematic reviews and clinical practice guidelines down to individual studies. It includes examples of searching databases such as MEDLINE, Embase and the Cochrane Library, as well as searching for grey literature and critically appraising the evidence found.
The document provides an overview of how to conduct a systematic search to identify relevant research for a systematic review. It discusses developing a clear research question, selecting appropriate databases and sources, developing a search strategy using subject headings and keywords, applying limits and screens, and exporting references to a citation manager. Tips are provided for developing an effective search strategy, applying it across multiple databases, and identifying additional relevant studies through other methods like hand searching. Contact information is given for experts available to help with the systematic search process.
BMJ Best Practice and BMJ Clinical Evidence are point-of-care decision support tools that combine the latest research evidence, guidelines, and expert opinion on prevention, diagnosis, treatment, and prognosis. They can be accessed through the La Trobe University Library databases. Users can browse topics or search for terms to find condition management information. Search results are organized by content type and relevance. Accounts can be created to save searches, bookmark pages, and access the resources mobilely. Help is available through various library guides and chat.
This document provides guidance on conducting an effective literature search to answer a research question about prosthetics and orthotics. It outlines how to formulate a well-structured research question, develop a search strategy using the PICO framework to identify relevant concepts and keywords, choose appropriate databases and search techniques, and evaluate search results. Effective searching requires using both controlled vocabularies and keywords to retrieve all relevant articles on a topic.
This document provides guidance on conducting an effective literature search to answer a research question in podiatry. It outlines how to formulate a well-structured research question using the PICO framework to identify relevant keywords and concepts. Different study designs and levels of evidence are discussed. Search strategies like using subject headings, Boolean operators and truncation are demonstrated. Finally, it recommends searching key databases and resources for podiatry literature, as well as refining searches and accessing full text.
This presentation was funded by CDC and PEPFAR through the SUCCEED project at Stellenbosch University. The presentation was delivered by Ms Lynn Hendricks from the Centre for Evidence Based Health Care in July 2017
Julie glanville embase sunrise seminar may 2016Ann-Marie Roche
Simple text mining tools can help Embase users in several ways:
- Frequency analysis of terms in records can identify useful search terms and concepts to explore. Tools like EndNote and Voyant allow viewing frequencies of words in titles, abstracts, and subject headings.
- Phrase analysis identifies common word combinations or concepts in the text, beyond single words. Voyant and TERMINE are useful for this.
- Word collocation analysis shows which words frequently occur near each other, suggesting relationships between ideas. The Voyant collocates tool supports this.
- Cluster and network visualizations identify major themes or concepts within a set of records. VOSviewer creates visual maps of related terms.
Exploring records
Describe the major available electronic resources
Describe how to build a search strategy
Describe some alternate sources for finding trials
Describe what to do once you get your search results
An introduction to conducting a systematic literature review for social scien...rosie.dunne
An introduction to conducting a systematic literature review for social scientists and health researchers presented by Luke van Rhoon Health Behaviour Change Research Group, School of Psychology, NUI Galway November 2020
Learn how to use Embase for all your biomedical searches
• Which workflows are supported by Embase and why
• An overview of content and indexing compared to Medline
• A demo in Embase of some introductory searches
• Answers to the most frequently asked questions by new users
• Where to find materials to support trainers
In this webinar we introduce you to the workflows supported by Embase, describe the benefits of Embase content and coverage and show you how you may utilize deep drug indexing to pinpoint and track biomedical information.
This document provides guidance on searching the medical literature. It discusses four categories of information resources, criteria for selecting resources, and five databases for finding primary studies. It outlines how to develop a search strategy, including turning a question into search concepts and keywords. It also covers running searches, applying screening criteria to search results, and synthesizing findings. The goal is to perform a systematic, explicit and reproducible search of the biomedical literature.
How to do a Literature search for your research and scientific publication BhaskarBorgohain4
Dr. Bhaskar Borgohain discusses strategies for conducting an effective literature search. He emphasizes defining a clear research question, brainstorming keywords, using appropriate search techniques like Boolean operators and filters, and keeping detailed records of the search process. Maintaining a search diary and using a citation manager are important for reproducing and organizing search results.
This document provides guidance on conducting an effective literature search, including how to formulate a research question, identify relevant keywords and concepts, consider appropriate levels of evidence, develop a search strategy using the PICO framework, use Boolean operators and subject headings, search appropriate databases and tracks additional relevant sources. It emphasizes breaking down the research question, using both controlled vocabulary and keyword searching across multiple databases, and adjusting the search as needed based on results.
The document discusses important considerations for developing an effective search strategy for systematic reviews, including:
1) Selecting appropriate databases and other sources based on the topic; searching MEDLINE, EMBASE, and CENTRAL at minimum.
2) Developing a focused research question to guide the search, listing relevant synonyms for participants and interventions.
3) Using controlled vocabulary and keywords, taking advantage of features like truncation, Boolean operators, and proximity searching to construct an optimized search string.
This document provides guidance on conducting an effective literature search to answer a research question in physiotherapy. It outlines the importance of developing a well-formulated question and considering the desired level of evidence. The PICO framework is introduced to break down the question into relevant concepts. Useful search techniques like Boolean operators, subject headings, limits and expanding/narrowing the search are described. Key databases for physiotherapy evidence are highlighted, including PEDro, Cochrane Library and BMJ Best Practice.
The document discusses conducting a systematic literature search to minimize bias. It describes searching multiple databases and sources in a thorough, objective and reproducible manner. Key steps include refining the clinical question, developing a search strategy using Boolean logic and Medical Subject Headings (MeSH) terms, searching bibliographic databases like PubMed and the Cochrane Library, and documenting the search strategy.
This document provides instructions for searching PsycBITE, a free database containing citations and summaries of research on psychological problems resulting from acquired brain impairment. It describes PsycBITE's contents and sources, how to access it through the La Trobe University Library website, tips for searching like using keywords and Boolean operators, an example search on exercise and depression in dementia, and how search results are rated for methodological quality. It also explains how to find full text and provides additional help resources.
The document provides an overview of how to find empirical evidence for clinical research projects, outlining key strategies and resources for developing effective search techniques and evaluating different levels of evidence, from systematic reviews and clinical practice guidelines down to individual studies. It includes examples of searching databases such as MEDLINE, Embase and the Cochrane Library, as well as searching for grey literature and critically appraising the evidence found.
The document provides an overview of how to conduct a systematic search to identify relevant research for a systematic review. It discusses developing a clear research question, selecting appropriate databases and sources, developing a search strategy using subject headings and keywords, applying limits and screens, and exporting references to a citation manager. Tips are provided for developing an effective search strategy, applying it across multiple databases, and identifying additional relevant studies through other methods like hand searching. Contact information is given for experts available to help with the systematic search process.
BMJ Best Practice and BMJ Clinical Evidence are point-of-care decision support tools that combine the latest research evidence, guidelines, and expert opinion on prevention, diagnosis, treatment, and prognosis. They can be accessed through the La Trobe University Library databases. Users can browse topics or search for terms to find condition management information. Search results are organized by content type and relevance. Accounts can be created to save searches, bookmark pages, and access the resources mobilely. Help is available through various library guides and chat.
This document provides guidance on conducting an effective literature search to answer a research question about prosthetics and orthotics. It outlines how to formulate a well-structured research question, develop a search strategy using the PICO framework to identify relevant concepts and keywords, choose appropriate databases and search techniques, and evaluate search results. Effective searching requires using both controlled vocabularies and keywords to retrieve all relevant articles on a topic.
This document provides guidance on conducting an effective literature search to answer a research question in podiatry. It outlines how to formulate a well-structured research question using the PICO framework to identify relevant keywords and concepts. Different study designs and levels of evidence are discussed. Search strategies like using subject headings, Boolean operators and truncation are demonstrated. Finally, it recommends searching key databases and resources for podiatry literature, as well as refining searches and accessing full text.
This presentation was funded by CDC and PEPFAR through the SUCCEED project at Stellenbosch University. The presentation was delivered by Ms Lynn Hendricks from the Centre for Evidence Based Health Care in July 2017
Julie glanville embase sunrise seminar may 2016Ann-Marie Roche
Simple text mining tools can help Embase users in several ways:
- Frequency analysis of terms in records can identify useful search terms and concepts to explore. Tools like EndNote and Voyant allow viewing frequencies of words in titles, abstracts, and subject headings.
- Phrase analysis identifies common word combinations or concepts in the text, beyond single words. Voyant and TERMINE are useful for this.
- Word collocation analysis shows which words frequently occur near each other, suggesting relationships between ideas. The Voyant collocates tool supports this.
- Cluster and network visualizations identify major themes or concepts within a set of records. VOSviewer creates visual maps of related terms.
Exploring records
Describe the major available electronic resources
Describe how to build a search strategy
Describe some alternate sources for finding trials
Describe what to do once you get your search results
An introduction to conducting a systematic literature review for social scien...rosie.dunne
An introduction to conducting a systematic literature review for social scientists and health researchers presented by Luke van Rhoon Health Behaviour Change Research Group, School of Psychology, NUI Galway November 2020
Learn how to use Embase for all your biomedical searches
• Which workflows are supported by Embase and why
• An overview of content and indexing compared to Medline
• A demo in Embase of some introductory searches
• Answers to the most frequently asked questions by new users
• Where to find materials to support trainers
In this webinar we introduce you to the workflows supported by Embase, describe the benefits of Embase content and coverage and show you how you may utilize deep drug indexing to pinpoint and track biomedical information.
Embase: Tips and tricks for trainers - 27 Feb 2013Ann-Marie Roche
In this webinar, Ann-Marie reviewed the following:
- How to demonstrate value in Embase
- How to scope out and build searches
- Where to find tools and materials for training.
This document provides information on searching strategies and drug information resources. It begins by outlining various searching techniques for databases, including the use of wildcards
This document discusses the difference between common practice and best practice in nursing. Common practice refers to the way things are typically done based on past experience, while best practice refers to the most effective way to do something based on research evidence. The document encourages nurses to engage in clinical inquiry by questioning current practices and searching research to determine if common practices should be changed or maintained. Nurses are asked to identify a clinical issue of interest, search the literature to find peer-reviewed research on the topic, and analyze the methodologies used in 4 research articles related to the issue.
Advanced literature searching for nursing dissertation 2019 sarahvr10
The document provides guidance on conducting an advanced literature search to find relevant articles for a research topic or question. It outlines a 6-stage process for searching: 1) identifying keywords, 2) selecting search terms, 3) applying search techniques, 4) selecting databases, 5) refining the search, and 6) final article selection. Examples are given for developing search strings using PICO/PEO frameworks and utilizing search techniques like truncation, Boolean operators, phrase searching and proximity operators to construct effective search strategies. The goal is to search in a structured and auditable way and to apply limits to focus the results.
Embase - Answers to your biomedical answers webinar - 27 Sept 2012Ann-Marie Roche
Our webinar was aimed at all biomedical researchers with a need to search biomedical literature and we focused on how content, indexing and specific search tools help you to find relevant answers.
Evidence based databases_Literature search.pptmohdbakar12
This document discusses strategies for finding evidence from medical literature, including:
- Formulating clear clinical questions using the PICO format
- Mapping the information landscape by identifying relevant keywords and concepts
- Deciding which evidence databases and sources are appropriate based on the hierarchy of evidence
- Learning how to effectively search databases using Boolean operators, subject headings, limits, and other tools
The overall aim is to help participants understand how to plan and conduct searches that retrieve high-quality evidence relevant to answering clinical questions.
This document provides an overview of evidence-based practice (EBP) and database basics. It discusses the EBP process and different types of studies used for EBP including practice guidelines, review articles, and research articles. The document then covers key aspects of the search process such as formulating questions, choosing search terms, using subject headings versus keywords, Boolean operators, and selecting appropriate databases. Examples are provided to illustrate searching PubMed and other resources.
This document provides an introduction to searching PubMed, the U.S. National Library of Medicine's database. It discusses accessing PubMed through a web browser or Google search. The document uses a sample search question ("What are the most effective drug therapies for adolescents with depressive disorder?") to demonstrate basic and advanced searching in PubMed. Basic searching involves entering terms in the search box, while advanced searching allows limiting searches to specific fields. The MeSH database is also introduced as a way to find controlled vocabulary terms for more precise searches. Hands-on exercises are provided to have the reader identify key terms in sample queries.
Advanced literature searching for Paramedic Science April 2019 sarahvr10
The document does not provide any substantive information to summarize. It contains a single word "Finding" with no additional context or details provided. No conclusions can be drawn from this very limited information.
The document provides an overview of conducting a literature review. It defines a literature review as analyzing significant research on a particular topic and placing one's own research question in the context of previous and current studies. The purpose is to evaluate research, recognize relevant sources, synthesize studies, and help answer the research question. It also discusses developing search strategies, evaluating sources, and writing the review. Key steps include formulating a question, identifying search terms, searching databases, appraising sources, and recording search methods.
Advanced literature searching for midwifery sarahvr10
The document provides guidance on conducting an advanced literature search. It outlines six stages of the literature search process: 1) identifying keywords, 2) selecting search terms, 3) applying search techniques, 4) selecting databases, 5) refining the search, and 6) making a final selection of articles. Search techniques discussed include truncation, Boolean operators, phrase searching, and using the PICO/PEO frameworks to develop an answerable research question and identify key concepts. The goal is to perform a structured, auditable search to systematically arrive at relevant research articles.
This document provides an overview of library resources and services available to NHS staff to help practice evidence-based medicine. It discusses the library collections, databases, and training programs available. Key services include access to books, journals, databases through OpenAthens, reference management support, and a four part information skills training program covering induction, searching, current awareness, and critical appraisal. The training program teaches skills for finding and evaluating evidence using a systematic approach to answer clinical questions and apply results to practice.
This document provides an overview of evidence-based practice (EBP) including its definition, importance, evolution, decision-making process, benefits, and misconceptions. It outlines a 5-step approach to EBP: formulating a question, finding evidence, appraising evidence, applying to practice while considering patient values, and evaluating effectiveness. Various resources and levels of evidence are also defined to help practitioners implement EBP and provide the highest quality, cost-effective care.
Finding the evidence - nursing apprenticeship sarahvr10
This document provides guidance on advanced literature searching. It aims to teach students how to search for journal articles to provide evidence for assignments. It covers developing search strategies using PICO/PEO frameworks, identifying keywords, selecting appropriate databases, applying search techniques, and documenting searches. The document recommends starting with key databases like Cinahl, Medline, and Cochrane, and provides tips for effective searching, such as using truncation and Boolean operators. The overall goal is to equip students with the skills to systematically and comprehensively find relevant evidence from the academic literature.
This document provides information about evidence-based resources available through an e-library. It begins with an overview of key e-library databases like DynaMed, Nursing Reference Center, and STAT!Ref. It then discusses how to effectively search within databases using Boolean operators, truncation, and other search techniques. The document concludes by emphasizing the value of evidence-based resources for supporting high-quality patient care and decision-making.
Literature searching msc chinese medicine 4th Dec 2015LesleyCB
This document provides guidance on conducting literature searches for an MSc in Chinese Medicine. It covers searching databases, search tips, authentication, sample searches, combining keywords, and accessing full text. Students are advised to break their topics into key concepts and identify synonyms. Databases, the library catalog, and interlibrary loans can be used to access full-text articles when subscriptions do not provide access. Feedback on the session can be left online.
Similar to Embase: Tips and tricks for trainers - Webinar, 27 Nov 2013 (20)
How predictive models help Medicinal Chemists design better drugs_webinarAnn-Marie Roche
All scientific disciplines, including medicinal chemistry, are experiencing a revolution in unprecedented rates of data being generated and the subsequent analysis and exploitation of this data is increasingly fundamental to innovation. Using data to design better compounds is a challenge for Medicinal and Computational chemists.
The design of small-molecule drug candidates, encompassing characteristics such as potency, selectivity and ADMET (absorption, distribution, metabolism, excretion and toxicity) is a key factor in the success of clinical trials and computer-aided drug discovery/design methods have played a major role in the development of therapeutically important small molecules for over three decades. These methods are broadly classified as either structure-based or ligand-based.
In this webinar our expert Dr. Olivier Barberan will discuss ligand-based methods and he will cover the following:
How to use only ligand information to predict activity depending on its similarity/dissimilarity to previously known active ligands.
- Discuss ligand-based pharmacophores, molecular descriptors, and quantitative structure-activity relationships and important tools such as target/ligand databases necessary for successful implementation of various computer-aided drug discovery/design methods in a drug discovery campaign.
Webinar: New RMC - Your lead_optimization Solution June082017Ann-Marie Roche
The document discusses Reaxys Medicinal Chemistry and how it supports hit-to-lead and lead optimization processes. It provides high quality data on topics like efficacy, ADMET properties, and animal models to help computational and medicinal chemists. The pX concept normalizes bioactivity measurements like IC50, Ki, and % inhibition into a single comparable metric, making it possible to compare compound affinity regardless of the metric reported. This allows researchers to more easily search for and analyze active compounds.
Oil&Gas Thought Leader Webinar - New Plays for Old Ideas - Dr.Gabor TariAnn-Marie Roche
In our April 2017 webinar, three industry experts shared their research and demonstrated the importance of focusing on fundamental geologic and geophysical research approaches that integrate variety of data, information and concepts from disparate sources and related disciplines.
This back-to-fundamentals research can both inspire and accelerate exploration teams’ thinking about petroleum systems and lead to a path to success.
Dr Gabor Tari is currently the Group Chief Geologist at OMV. He has over 20 years’ experience working in upstream oil & gas and has worked for Amoco, BP, and Vanco, before joining OMV in 2007. Gabor has worked on exploration projects in basins around the globe, including Romania, Angola, North Africa, and the Middle East. He has authored over 50 scientific publications, presented papers at dozens of conferences, and most recently co-authored the book Permo-Triassic Salt Provinces of Europe, North Africa and the Atlantic Margins, with Dr Joan Flinch (Repsol) and Juan Soto, Professor of Geodynamics in the Granada University and in the Instituto Andaluz de Ciencias de la Tierra, Spain, which is currently available from Elsevier for pre-order online.
Gabor discussed and shared some examples of how new plays can be built on a solid foundation of petroleum system development and research, and how new ideas can be garnered from building on published research of oil & gas companies, academia, service providers and consultants.
Oil&Gas Thought-Leader Webinar - New Plays for Old Ideas - Dr. Rob ForknerAnn-Marie Roche
In our April 2017 webinar, three industry experts shared their research and demonstrated the importance of focusing on fundamental geologic and geophysical research approaches that integrate variety of data, information and concepts from disparate sources and related disciplines. This back-to-fundamentals research can both inspire and accelerate exploration teams’ thinking about petroleum systems and lead to a path to success.
Dr Rob Forkner is a carbonate geologist at Statoil, working in the carbonate plays and reservoirs research group in Austin, Texas, focusing on carbonate play prediction in Atlantic margin systems. Prior to Statoil, Rob worked at Maersk and Shell in onshore and offshore in well planning, geosteering, high-resolution sequence stratigraphy and facies prediction, carbonate sedimentology in unconventional assets, evaporite classification and prediction, rock typing, and more recently, carbonate system suppression and recovery during Oceanic Anoxic Events.
Oil&Gas Thought-Leader Webinar - New Plays for Old Ideas - Dr. Sander HoubenAnn-Marie Roche
Dr. Sander Houben presented on combining paleoceanographic and exploration tools to study Early Jurassic anoxic events. He discussed how carbon isotopes can be used as a stratigraphic tool to analyze perturbations to the carbon cycle during these events. Palynological analysis of indicators of photic zone anoxia and chemocline migration provided insight into changes in water column ecology. A case study of the Toarcian OAE and Posidonia Shale Formation showed how isotopic analyses revealed a major increase in export of hydrogen-rich organic matter due to intensified primary productivity by diazotrophs under low oxygen conditions. Paleoceanographic observations combined with an exploration geology perspective provided understanding of the formation of
Embase for pharmacovigilance: Search and validation March 22 2017Ann-Marie Roche
Scientific literature plays a critical role in Pharmacovigilance and Drug Safety workflows. Monitoring literature for mentions of adverse drug reactions (ADRs) is mandated by regulatory bodies, and marketing authorization holders (MAHs) that do not properly report ADRs can be subject to heavy fines. With an increasing volume of unstructured content to cover, along with rising labor costs, MAHs are looking for ways to make their literature monitoring more effective and efficient.
Abstract and indexing (A&I) databases play an important role in Literature Monitoring – due to the vast amount of scientific literature published daily – in order for MAH’s to locate specific articles or conference presentations that may be relevant for their products (for both benefit/risk analysis and ADR detection). Rather than reading all the literature, MAH’s create search strategies that identify the relevant records in A&I databases and execute the searches regularly. GVP module VI mandates that searches are done at least weekly, but many companies maintain a daily monitoring and review cycle.
In this webinar, Senior Product Development Manager Embase, Dr. Ivan Krstic discussed best practices for saving time, staying current, validating search strategies and mitigating risk in the face of these increasingly complex processes in literature monitoring
Literature Management for Pharmacovigilance: Outsource or in-house solution? ...Ann-Marie Roche
Pharmaceutical companies are required to screen scientific literature on a regular basis and this comes with many challenges, such as handling large amounts of data, building search strings and integrating EMA MLM results. Out-sourcing literature screening to service providers reduces the workload for the PV-team, but how does it impact the literature management process overall? Maybe it results in decreased oversight and additional activities like audits and reconciliation? And what about building the search strategy?
During this webinar our PV expert, Dr. Joyce De Langen spoke about the following:
• The importance of literature management in Pharmacovigilance and the challenges.
• An evaluation of the benefits and risks of outsourcing literature management versus alternative solutions.
About the speaker:
Joyce de Langen, Ph.D has more than 10 years of experience in the domain of pharmacovigilance and drug safety. Through her work in the pharmaceutical industry, academia and regulatory authorities, Joyce has developed a broad perspective and knowledge in pharmacovigilance and drug safety.
Finding the right medical device information in embase 11 2016Ann-Marie Roche
The document discusses guidelines for systematic reviews of biomedical literature in Clinical Evaluation Reports (CERs) for medical devices, highlighting how Embase addresses the requirements through its comprehensive indexing of devices, manufacturers, and adverse effects, as well as features for building sensitive searches. It also provides examples of searches in Embase to find information on device clinical performance, comparisons, and safety for a case study on an everolimus eluting coronary stent.
The document discusses medical device adverse event reporting requirements, including definitions of reportable events and timelines for submitting reports to regulatory agencies. It provides an overview of the classification system for medical devices and regulations around reporting malfunctions, deaths and serious injuries caused by devices. Reporting requirements and challenges involving software as a medical device are also reviewed.
The All-New 2016 Engineering Academic Challenge - developed by students for students
The Engineering Academic Challenge (formerly as the Knovel Academic Challenge) is an immersive, 5-week interactive problem-set competition, featuring weekly thematic engineering challenges built around five transdisciplinary themes inspired by the National Academy of Engineering Grand Challenges.
Literature monitoring for pv what are we doing at galderma elsevier webinarAnn-Marie Roche
The document discusses literature monitoring for pharmacovigilance. It describes weekly monitoring of individual case safety reports and periodic monitoring through development safety update reports and periodic benefit-risk evaluation reports. Key databases for literature searches are Medline and Embase. While Embase has more extensive drug coverage, searches on Medline via PubMed are more reliable due to the potential for loss of MeSH subheadings when mapping to Emtree and the risk of false negatives and positives when searching Embase alone. Literature searches support signal detection and periodic evaluation of a product's safety profile.
This document discusses how drug analytics based on manually extracted semantic relationships in Embase can be useful for drug development, repurposing, and safety. It describes how relationships between drugs, diseases, and adverse reactions that are manually indexed can provide valuable information for drug repurposing, development, and safety. Specific examples are provided to show how the semantic relationships can guide drug repositioning strategies, investigate new combination drugs, identify drug-drug interactions, collect drug comparison data, and help improve risk management.
This document discusses Lean Six Sigma and resources available through Knovel to support Lean Six Sigma implementation. It provides an overview of the Lean Six Sigma implementation process including strategic leadership and vision, deployment planning, and execution and results. It describes Knovel's Lean Six Sigma resources such as handbooks, case studies, templates, and guides covering tools like DMAIC, DOE, SPC etc. that can help with the different belts and project phases from Define to Control. Other resources discussed include those for Design for Six Sigma and practical applications/case studies.
Reaxys provides a unified information portal that integrates data from multiple chemistry sources through a single interface. It links chemistry data, structures, citations, and full-text articles. Reaxys also integrates in-house data from sources like electronic lab notebooks through its API and can be used for activities like compound screening, literature searching, and patent analysis to support drug discovery.
Phil Lorenzi discusses pathway analysis approaches and their uses in biomedical research and drug development. He compares strategies for analyzing the autophagy and apoptosis pathways, finding that integrating multiple methods provides the most comprehensive understanding. Lorenzi also provides examples of how pathway analysis could have predicted problems with COX-2 inhibitors and helped explain past failures of AKT inhibitors. He concludes that pathway analysis is consistent with approvals of EGFR, MEK, RANKL and PARP inhibitors and may support development of GLS inhibitors.
Searching literature databases for post authorisation safety studies (pass)Ann-Marie Roche
This document discusses using literature databases like Embase to conduct post-authorization safety studies (PASS) through systematic literature reviews and meta-analyses. It provides an example PASS on the drug brentuximab vedotin that identified adverse events like peripheral neuropathy and infections. The document reviews how to structure a literature search using the PICO framework and Embase's in-depth indexing of concepts, relationships, and causality to comprehensively identify safety outcomes reported for a drug.
Ian crowlesmith embase retrospective mla 2016Ann-Marie Roche
Embase began in 1946 as Excerpta Medica, founded to provide medical abstracts. It was acquired by Elsevier in 1971 and became available online in 1978. Key developments included introducing a controlled vocabulary called Emtree in 1987 and adding item types and check tags for evidence-based medicine in 1990. Currently, Embase indexes articles in great depth using natural language and extensively covers drugs and devices. The taxonomy Emtree is regularly updated to reflect new terms.
The document provides an update on new features and enhancements to Embase.com. Key points include:
- The addition of a new PICO search page that allows users to build clinical searches by splitting questions into Patient, Intervention, Comparison, and Outcome elements.
- Other enhancements include improved search tips, the ability to add synonyms and view all abstracts, as well as analytics capabilities for drug safety and repurposing based on triple indexing of content.
- Future plans include improvements to content, taxonomy, and indexing as well as a revamp of the search platform interface and functionality.
This document discusses upcoming changes to process safety management (PSM) regulations and standards. It notes several major industrial accidents in recent decades that prompted reforms. New PSM requirements in California will likely be adopted more widely and require more prescriptive tasks, reporting, and accountability. To ensure future PSM success, the document recommends: making no distinction between internal/external compliance; expanding the definition of mechanical integrity; understanding "double jeopardy"; not replacing investigations with management of change; knowing what the operations team is doing; and clarifying teamwork expectations regarding stop work authorizations.
This document describes a collaboration between Findacure, a UK charity focused on rare diseases, and Elsevier to mobilize informational resources for congenital hyperinsulinism (CHI), a rare genetic disease. Elsevier will provide Findacure access to its extensive literature database and text mining capabilities to summarize what is known about CHI mechanisms, identify potential drug targets, and find approved drugs that may treat CHI. The collaboration aims to support Findacure's efforts to drive research, develop treatments, and help patients by providing structured, analyzed information extracted from Elsevier's literature and linking researchers and institutions working on CHI.
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8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
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Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
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2. Need to know
• Webinar control panel:
– ‘chat’ or ‘ask a question’ for
questions and comments
– Option for full screen view
• Q&A during and time at end.
3. CONTENTS
• Tools
• Why Embase and who uses Embase
• Guiding users through…
– Initial investigation
– Setting up search strategies
– Refining, editing and managing
search results
3
4. SUPPORT TOOLS
• Customer support and training page
•
Webinars
•
Search Guides and white papers
•
Videos
• Revamping
Help and
Support in
Embase
• Newsletter registration
4
5. WEBINARS IN EMBASE
Webinar overview 2013
• Intro webinars – once a quarter
• Topic webinars – Evidence-Based-Medicine, Adverse Events, Emtree,
Tips and Tricks for trainers
• 12 webinars in 2014
Webinars in 2014
• Looking for ideas from you from you for NEW webinars
• Extending the number of intro webinars to other time-zones and
languages
• Repeat popular topics from this year and include priorities like
Medical Devices
5
6. NEW VIDEOS
CURRENTLY ON WWW.ELSEVIER.COM/ONLINE-TOOLS/EMBASE/CUSTOMER-SUPPORT BUT MOVING TO
WWW.ELSEVIER.COM/ONLINE-TOOLS/EMBASE/TRAINING-AND-SUPPORT
• Getting started
• Designing your search
• Refining your search
• Managing your search
• Setting up and managing email
alerts and saved searches
6
9. HOW EMBASE DELIVERS VALUE
...by including literature and information
resources in a timely manner
...by reading full-text to identify
drugs, diseases, adverse affects,
clinical trials, drug trade names etc.
...by enabling advanced search filters to
drill down a comprehensive search to a
relevant and manageable record set
Conference
proceedings
Scientific
Journals
In Press
(unpublished)
Deep indexing using own
taxonomy (EMTREE)
Very powerful
Search
Environment
...by allowing users to automate
searching and result management
We make sure you don’t
miss any
biomedical literature
They only close
alternative is reading
all the articles
Good precision and
recall balance
Automation and
documentation
E-mail Alerting
API
Interoperability
9
9
10. BEING AS COMPREHENSIBLE AS POSSIBLE
SOURCE
Efforttools required
TEXT
MINING
EMBASE
SCOPUS
PUBMED
GOOGLE
E
0%
50 %
100 %
Percentage of relevant articles retrieved
10
11. WHO BENEFITS FROM USING EMBASE
• Systematic reviews of the (biomedical) literature
• Health Technology Assessments or rapid advisories
• Comparative Effectiveness Reviews
• Post-market surveillance and / or clinical evaluations for Medical Devices
• Comprehensive „scanning/monitoring‟ literature for drug adverse effects, emerging
public health threats, off-label drug use, efficacy, medication errors, drug-drug
interactions, abuse and misuse, quality complaints, counterfeiting, inaccurate or
inappropriate statements on drugs and devices in data. Common heading could be
Pharmacovigilance.
•
If users have a more „general‟ research need – Scopus for example is a great solution.
11
12. FAQS
• How current is Embase. Does it have AIP and In Process for
example?
• Where do conference abstracts come from?
• Is all of MEDLINE in Embase? Therefore do I NOT need to search
both? Check out our Embase/MEDLINE and differences between
Emtree/MeSH white paper
• Why do I need indexing?
12
13. Content
Emtree: Biomedical thesaurus, over 60k terms
1947
1950
1974
2009
Embase: Fully indexed: Over 8,000 journals, 1974(5.5M not in MEDLINE)
MEDLINE: 2,500 journals unique to Embase, mapped to Embase
indexing, 1950- (including MEDLINE Classic)
Embase Classic:
Digitally scanned and
re-indexed, 1947-1973
AIP and In Process:
Indexing added, from 2009
Conference Abstracts:
Indexing added, from 2009
http://www.elsevier.com/online-tools/embase/about
15. INDEXING
1. TRANSLATE
To bring the semantic richness of medical terminology within your
grasp: mapping many synonyms to a single (natural language)
preferred terminology
2. EXPAND
To expose and summarize the information in biomedical articles
beyond title and abstract: discovering in-depth data about
drugs, diseases and medical devices
3. FOCUS
To identify the key concepts hidden within those articles – what
they are really about – providing you with a toolkit to find
answers beginning with comprehensive searches
15
16. INDEXING
MEDLINE INDEXING IS MAPPED TO EMTREE TERMS
SEE WHITE PAPER: COVERAGE OF MEDLINE ON EMBASE
“When MeSH terms are
mapped to Emtree,
subheadings are mapped to
Embase subheadings.
Since not all MeSH
subheadings have an exact
Emtree equivalent, some of
them generate Emtree terms
rather than subheadings.”
16
18. Meet Karol, an information specialist
supporting pharmacovigilence. Karol
needs to ensure that she is setting up
searches across all relevant sources, to
track all adverse events for 3 of their
products on the market. There is so much
info to track and she struggles to be
confident when reporting.
Let‟s dive in and show her how she may
quickly review all side effects for her
drugs, saving her time, while being
confident that she is not missing anything
with Embase‟s current and unique
content.
21. START SEARCHING
FIND THE BEST TERMS FOR YOUR SEARCH AND INCLUDE SYNONYMS
AUTOMATICALLY WITH AUTOCOMPLETE IN QUICK SEARCH
34
22. CHECK FILTERS
CLICK ON DISEASE FILTER FOR EXAMPLE, TO SEE WHICH DISEASES ARE
REFERENCED WITH JANUVIA, EITHER AS A THERAPEUTIC AREA OR SIDE
EFFECT.
35
23. CHECK ARTICLES FOR SEARCH TERMS
Find interesting search terms or drug and disease
relationships without having to consult the full text.
36
25. START WITH EMTREE
Search for over 60K terms,
including MeSH terms and over
30K drug and chemical terms
Click here to search further in an
Embase search form, mapping all
synonyms
Click here to the see the results,
exploded
38
38
26. REVIEW EMTREE TERMS
Consider the term’s History
Take note of any Synonyms listed
Look at the CAS registry number(s) displayed
Read the entry provided from
Dorland’s dictionary, when
available
39
27. REVIEW QUESTION 1
•Track the efficacy of saxagliptin in treating diabetes type 2 and
compare to other dipeptidyl peptidase 4 inhibitors
•Investigate the use of subheadings, such as:
‘Pharmacokinetics’, ‘Adverse Drug Reaction’, ‘Drug Toxicity’
•Use explosion to investigate other depeptidyl peptidase 4
inhibitors
40
28. REVIEW QUESTION 2
Find disease management studies for Type II diabetes
•Look for your term in Emtree
•Use the disease search form for disease subheadings.
•Use major focus to limit your results.
41
29. REVIEW QUESTION 3
• Evaluate the evidence for suicide risk in children treated for
depression with SSRIs
• Evaluate the evidence that children treated for depression
using serotonin reuptake inhibitors are at increased risk of
suicide
42
30. REVIEW QUESTION 4
• What are the pro’s and con’s for metal-on-metal hip implants vs
other types of hip prosthesis?
• What are the pro’s and con’s for metal-on-metal hip implants
vs other types in different patient groups?
43
31. BUILD AND COMBINE SEARCHES
REFER TO HELP FOR MORE GUIDANCE AND LINKS TO MATERIALS SUCH
AS THE QUICK USER GUIDE.
• Use single quotes to capture a phrase „diabetes mellitus‟ for example (not
with Autocomplete in Quick Search)
• Break up your search into individual searches, such as a drug search (in
Drug Search form) and a disease search (in Disease Search form) and
combine your results in Session Results
• Run your cursor over your search to Edit or copy to a Search Form for
guided editing.
• Truncation and operators, AND, OR, NOT, NEXT, NEAR
44
32. BUILD AND COMBINE SEARCHES
REFER TO HELP FOR MORE GUIDANCE AND LINKS TO MATERIALS SUCH
AS THE QUICK USER GUIDE.
• Use single quotes to capture a phrase „diabetes mellitus‟ for example (not with
Autocomplete in Quick Search)
• Break up your search into individual searches, such as a drug search (in Drug Search
form) and a disease search (in Disease Search form) and combine your results in
Session Results
• Run your cursor over your search to Edit or copy to a Search Form for guided editing.
• Truncation and operators, AND, OR, NOT, NEXT, NEAR
45
34. STUDY TYPES AND TOPIC TERMS
• From Emtree facet “Types of article or study”
• Include many more terms than check tags
• Now include “Topic terms” (from 2011)
Topic terms: 10 terms ending with (topic)
Topic terms were introduced in 2011 to differentiate between study
types, indexed when the article IS the primary report for an RCT
(for example), and articles in which that term is only a topic that is
discussed.
47
35. REFINING YOUR SEARCH
CHECK OUT OUR TRAINING VIDEOS AT FOR MORE GUIDANCE
• Quick and Advanced Limits on Advanced, Drug and Disease Search forms
• Major Focus on all advanced forms – major drugs and diseases retrieved
• Field limits under Advanced Search box to search in specific fields such as article title,
abstract, conference name, drug name etc
• Drug and Disease Subheadings to limit to specific concepts such as Adverse Drug
Reaction, Drug Comparison and Side Effect.
• Filters on Session Results page for specific diseases or study types for example
Check out our training videos at www.elsevier.com/onlinetools/embase/customer-support#videos for more guidance.
48
36. REGISTERING FOR EMAIL ALERTS AND SAVE
SEARCHES
•Setting up email alerts
•Saving your searches
•Staying up to date
49
49
37. SAVING SEARCHES
• Save in personal folders or share your saved searches.
• Edit sub-searches within your main search strategy and rerun
• Re-use a save search - #name in future searches
50
39. THANK YOU
• Our next intro webinar is Jan 22 2014!
• You may review our up to date webinar schedule on our webinar
page.
• Slides and recording will be sent as well as any further questions?
52
Editor's Notes
Where do you go for tools?What do you like to use when training or presenting on Embase?What have you found useful?
The story is essentially that as you move closer to doing a 100% comprehensive literature search – your costs / time investment go up exponentially. Therefore, it’s only worth buying an Embase sub or employing an Embase related /based text mining solution, if the use case requires you to get close to that 100% coverage (PV, systematic reviews, clinical evaluations / investigations, HTA’s etc.) It’s a framework that we could use more extensively to position Embase and to defend / substantiate pricing. For example , when we are selling Embase, we’re not selling 28 million records, we’re selling the possibility to go from 70/80% retrievability on any particular topic, to (let’s say) 95%. Of course, the only way to get to a 100% is to buy and read every relevant journal there is and visit every conference. Needless to say the solution that would require the most time / investment and would be virtually impossible to do on a regular basis (postmarket surveillance).
Impact of increased regulatory pressures in PV continue to drive interest among small & mid Pharma, consultancy agency’s and generic manufacturers. As new ’12 PV standards are being applied, Pharma is being audited. As a consequence they are stepping up their scrutiny on the quality of data and PV service providersEvidence Based Medicine continues to grow and we see an increased number of signups and quotes from the HS domain (Embase being offered in conjunction with Clinical Key). Systematic reviews and spinoffs (HTA’s, Comparative Effectiveness Reviews, Rapid Evidence Advisories) continue to drive the need for Embase in the Academic and Government domain. In the medical devices domain adaption of new ‘safety’ requirements is influenced by a 5-year grace period.
Some examples of commonly asked questions. Any other questions at this point?
To help you and your users visualize the content in Embase, you can use this diagram. This shows the Embase content, combined with MEDLINE going back to 1960 and with Embase Classic going back to 1947. Embase AIPs. In Process and Conference Abstracts ensure users have the opportunity to review the most recent research as soon as possible. We are looking into adding MEDLINE AiPs and In Process this year.And to look at the overlap in more detail…
All of Embase and all of MEDLINE are in Embase.com, with minimum duplication. We choose for Embase record . We will address some questions on this later.the The strategy for searching for Embase ONLY is included. This search will NOT include Medline unique and records which are overlapping Embase/MEDLINE.
Let’s take a high level view of what is happening with indexing.Probably like all databases, Embase indexing serves three main roles: to translate (**), expand (**), and focus (**).What is specific to Embase is how we interpret each of these aspects.For example:Under the heading translation, what is special about Embase is the natural language terminology used for indexing, and the very large number of synonyms.expansion stands for the in-depth indexing of drugs, diseases and in fact also medical devices which is derived from the full text of the articleand focus refers to the specific tools that Embase makes available to help you drill down to the articles you need.
A few things to focus on:MEDLINE records in Embase: For all these records, we use the MEDLINE indexing, which we map against Emtree in order to ensure that these MEDLINE records are fully retrievable in all searches using Emtree.(**) The details of how we do the mapping are described in the white paper whose URL is shown here.(**) For example, the mapping for MeSH subheadings has to take into account that for some of them there is no equivalent Embase subheading.
For example:May I introduce Pierre. Pierre is a clinical liaison librarian, in the Information Services Biomedical Library, Center for Evidence-Based Research. They work with 3 main hospitals.Pierre has many concerns,for example, he instructs users in the use of library resources and management of information and he assists with literature searches on evidence-based practice issues, consulting with staff conducting systematic reviews with regards to search strategies. He serves as the primary library contact for many of the resources used by clinicians. Hisusers are mainly involved in finding information from relevant and reliable sources regarding the effects of different forms of healthcare and they must be thorough when conducting this research and when publishing.His users are preparing articles for publication and they hear more and more that journal editors and referees now stipulate that Embase searches are needed and authors publishing in the field of EBM, who need to follow Cochrane guidelines MUST conduct Embase searches. How can he best incorporate this into their workflow? Some users are still convinced that MEDLINE is enough and some have even asked about Scopus. Let’s have a look at the unique value Embase offers and also how easy it is to search with confidence!
The PERFECT DEMO for Embase. Here we show you the answer and now let’s see how Embase helps you to get there quickly and effectively.
One of the major steps in conducting a systematic review is a comprehensive literature search. With Embase, all users, regardless of experience may enter the best term or terms to search, even on the Quick Search page. An user with more experience may have more success with knowing which terms to use to retrieve workable results from non-thesaurus options, Google and Scopus shown here for example but what if you do not have this experience, there are no prompts like you see in Embase.
Pubmed (Medline) does allow thesaurus searching but here also we notice a difference in the number of results retrieved. Pubmed finds 132 results compared to 8,000 in Embase. We know there is unique content in Embase, the conference abstracts shown here for, but there is also a difference in indexing focus and so Embase indexes more drugs and more deeply.
In Medline, this article although present in Medline is not indexed with digoxin and therefore our search for digoxin and antibacterial agents did not find this article. As we know already, it is found in Embase.For those of you who would like to dive into this search in more detail:Antibiotic and digoxin with drug combinationANDCongestive heart failure with drug therapyAND PneumoniaSave this search – remove drug therapy from disease and rerun main searchNow in session results, remove drug comparison from drug sub-searches and note asterix (indicates which searches have been effected by a change to a related search)– now click on result number to update your search strategy.Compare the effectiveness of sitagliptin and saxagliptin in the treatment of type II diabetes mellitus (show this in Emtree)Go to Drug Search and type in sitagliptin and saxagliptin with drug comparison. Go to Emtree and show diabetes mellitus and then go to ‘type 2 diabetes mellitus’. Take this to Disease Search and combine with disease subheading ‘drug therapy’. Combine both searches.Show editing options. NOT [review]/limAdvanced combine on the Session Results: Last search above NOT saxagliptin search, for example #2 NOT #1.Show Emtree to find suitable terms/subject headings and then using Drug Search to add subheadings.
Second poll? – what are pain points?What are other examples here to engage audience and find out more about them? List professions? List tools they know and use? As about main tasks?
How are you going to start searching for all the synonyms in a non-thesaurus database, such as Scopus? In Embase, we search for our drug, including all the synonyms. We added the drug concept/subheading, ‘adverse drug reaction’ and ‘drug toxicity’ and here we search for a specific relationship with the drug. This is not possible in Scopus.
How are you going to start searching for all the synonyms in a non-thesaurus database, such as Scopus? In Embase, we search for our drug, including all the synonyms. We added the drug concept/subheading, ‘adverse drug reaction’ and ‘drug toxicity’ and here we search for a specific relationship with the drug. This is not possible in Scopus.
Now we have introduced a scenario and shown some searching in Embase. We can continue to search and ask the audience to prompt us with the next steps...
This is where we get started and try to find the best terms for our search for example.POLL
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Starting with Emtree to find suitable terms/subject headings and then using Drug Search to add subheadings. Search saxagliptin with pharmacokinetics and combine with ‘type 2 diabetes mellitus’ with disease subheading ‘drug therapy’.Go back and search for dipeptidyl peptidase IV inhibitors exploded. Copy back to drug search and combine with pharmacokinetics. Combine with previous disease search.Advanced combine on the Session Results: Last search above NOT saxagliptin search, for example #2 NOT #1.
Starting with Emtree to find suitable terms/subject headings and then using Disease Search to add subheadings. From Session Results, you can edit in-line by moving your mouse over the search strategy and selecting Edit. Try using /de and :de for exact search and phrase search. Human/de picks up records where human is in the index field and human:de picks up aspects of human. Selecting human from the Advanced Search form searches /de.When looking for exact journal names, such as biochemistry, use /jt. From the Session Results, we may also Copy to Disease Search form and use major focus.Refer to www.trainingdesk.elsevier.com/embase and the Quick User Guide for more guidance
Emtree to disease search => depression/exp/dm_dt (= drug therapy)Limits => [child]/lim OR [adolescent]/limEmtree to drug search => serotonin-uptake-inhibitor/exp/dd_dt (via synonym search for SSRI)1 AND 2 AND 3Emtree => suicide/exp4 AND 5Filter => view & select levels of evidence
Emtree => hip-prosthesis/expMetal-on-metal (after reviewing Quick search / autocomplete) Avoid relying on metal-on-metal joint prosthesis, introduced 20131 AND 2Filter => select comparative-study, intermethod-comparisonEdit => replace by compar* (compare free text vsEmtree results)Emtree => treatment outcome Filter => view & select levels of evidence
Compare the effectiveness of sitagliptin and saxagliptin in the treatment of type II diabetes mellitus (show this in Emtree)Go to Drug Search and type in sitagliptin and saxagliptin with drug comparison. Go to Emtree and show diabetes mellitus and then go to ‘type 2 diabetes mellitus’. Take this to Disease Search and combine with disease subheading ‘drug therapy’. Combine both searches.Show editing options. NOT [review]/limAdvanced combine on the Session Results: Last search above NOT saxagliptin search, for example #2 NOT #1.Quickly show Emtree to find suitable terms/subject headings and then using Drug Search to add subheadings.
Now, as you’ll recall, the check tags include a group of study types, such as “major clinical study” and “randomized controlled trial”.Another way of finding study types is to use the Filters at the left hand side of the results page, which I mentioned a few moments ago.(**) All of the study types mentioned here for one particular search are taken from the Emtree facet on “Types of article or study”(**) This is a rich source of terms that you can use to filter your search, and it now includes 10 so-called topic terms shown here, that I described last month in an Embase webinar on Evidence Based Medicine. If you want to follow up on this, you can access those slides via the Embase info site.This definition of topic terms, by the way, mirrors the definitions of similar terms which the NLM uses to index MEDLINE.
Find disease management studies for Type II diabetesGo to Emtree and type in diabetes. Once you see the tree, select non-insulin dependant diabetes mellitus. Click on ‘take this to Disease search’. Point out ‘major focus’ option if users would like to limit their search to only records where the disease is of major importance and show on Disease Search form. Shoe quick and advanced limits.You can then add the subheading ‘disease management’. Check filters for drugs and study types.
Don’t loose those important searches, register in Embase so you may save your searches or set up email alerts. Registering also means you receive all up to date information such as upcoming webinars.Antibiotic and digoxin with drug combinationANDCongestive heart failure with drug therapyAND PneumoniaSave this search – remove drug therapy from disease and rerun main searchNow in session results, remove drug comparison from drug sub-searches and note asterix (indicates which searches have been effected by a change to a related search)– now click on result number to update your search strategy.Re-use a named search in a new search. For example you may have a group of #limitstrial AND digoxin
Antibiotic and digoxin with drug comparisonANDCongestive heart faliure with drug therapyAND PneumoniaSave this search – remove drug therapy from disease and rerun main searchNow in session results, remove drug comparison from drug sub-searches and note asterix (indicates which searches have been effected by a change to a related search)– now click on result number to update your search strategy.Re-use a named search in a new search. For example you may have a group of #limitstrial AND digoxin