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Embase: Tips and tricks for trainers - 27 Feb 2013
- 1. Welcome to our Embase webinar program! Tips and tricks for trainers Your presenter: Ann-Marie Roche
- 2. Agenda • Tools • Demonstrating value with case study • Guiding users through… o Initial investigation o Setting up search strategies o Refining, editing and managing search results • Q&A
- 3. Need to know • Webinar control panel: o ‘chat’ or ‘ask a question’ for questions and comments o Option for full screen view • Q&A during and time at end.
- 4. Tools • Info site o Webinars o FAQs o White papers, including MEDLINE in Embase o Newsletter o Links to videos on Training Desk • NEW Training and Support site coming in April!
- 6. Content overview Emtree: Biomedical thesaurus, over 60k terms 1947 1950 1974 2009 Embase: Fully indexed: Over 8,000 journals, 1974- MEDLINE: 2,500 journals unique to Embase, mapped to Embase indexing, 1950- (including MEDLINE Classic) Embase Classic: AIP and In Process: Digitally scanned and Indexing added, from 2009 re-indexed, 1947-1973 Conference Abstracts: Indexing added, from 2009 http://www.embase.com/info/what-is-embase/coverage
- 7. Content overlap Embase MEDLINE 5.5m 10m 9m 2000 3000 2500 [embase/lim] NOT [medline]/lim
- 8. How is Embase delivering value? ...by including literature and information Conference Scientific In Press We make sure you don’t resources in a timely manner proceedings Journals (unpublished) miss any biomedical literature ...by reading full-text to identify drugs, diseases, adverse affects, Deep indexing using own The only close alternative is reading clinical trials, drug trade names etc. taxonomy (EMTREE) all the articles ...by enabling advanced search filters to drill down a comprehensive search to a Very powerful relevant and manageable record set Good precision and Search recall balance Environment ...by allowing users to automate Automation and searching and result management documentation Email alerting API Interoperability 8
- 9. Case study A clinician is working on a systematic review for publication. She needs to adhere to certain guidelines to ensure she has conducted a through search of the literature. Question Are there any risks associated with the administration of antibiotics together with digoxin in a patient with congestive heart failure who has contracted pneumonia?
- 10. Articles like this contain vital information…
- 11. Comprehensive searching in Embase 11
- 12. 2 sets of results…Why are the results so different and does it matter…?
- 13. 23 synonyms as well as ‘antibacterial agent’ are searched simultaneously as well as over 38 narrower terms (including moxifloxacin). No simultaneous searching of synonyms or narrower terms= Only ‘antibacterial agent’ is searched and this does not find all the vital information
- 14. Our article is found in the Embase results… …Not in our non-thesaurus assisted search
- 15. 2 thesaurus assisted searches but different results? There is unique content such as conference abstracts? Anything else?
- 16. Our article is found in the Embase results… … Not in MEDLINE, as MEDLINE does NOT index digoxin in this article.
- 17. Unique content in Embase Presented by Carol Lefebvre MLA 2010 • ‘Embase is a rich source of reports of randomized trials that are either not included in MEDLINE or not indexed as trials in MEDLINE, especially reports in some languages other than English’. • ‘In addition to searching CENTRAL, people looking for reports of randomized trials should search Embase, as well as MEDLINE, for reports published in recent years that have not yet been considered for inclusion in CENTRAL’. Ref: Lefebvre et al. Emerging Themes in Epidemiology 2008 5:13
- 18. Questions • What is the difference between AIP, In Process and fully indexed records and why does Embase have all 3? • Where do conference abstracts come from? • Is all of MEDLINE in Embase? Therefore do I NOT need to search both? http://www.embase.com/info/UserFiles/Files/Coverage%20of%2 0Medline%20in%20Embase.pdf
- 20. Start searching… Find the best terms for your search and include synonyms automatically with autocomplete in Quick Search
- 21. Check filters… Click on Disease Filter for example, to see which diseases are referenced with Januvia, either as a therapeutic area or side effect.
- 22. Check articles for search terms… Find interesting search terms or drug and disease relationships without having to consult the full text.
- 24. Start with Emtree Search for over 60K terms, including MeSH terms and over 30K drug and chemical terms Click here to search further in an Embase search form, mapping all synonyms Click here to the see the results, exploded 3 x updates per year. www.embase.com/info/emtree for 24 more information
- 25. Reviewing an Emtree term Consider the term’s History Take note of any Synonyms listed Look at the CAS registry number(s) displayed Read the entry provided from Dorland’s dictionary, when available 25
- 26. Backposting • Emtree terms changes such as trade name and now generic name – How do you find ALL articles, NOT only those indexed from the date of the new term? • BACKPOSTING!
- 27. Review Question •Tracking the efficacy of saxagliptin in treating diabetes type 2 •Comparing the efficacy/safety of dipeptidyl peptidase 4 inhibitors •Investigate the use of subheadings, such as: ‘Pharmacokinetics’, ‘Adverse Drug Reaction’, ‘Drug Toxicity’ •Use explosion to investigate other depeptidyl peptidase 4 inhibitors 27
- 28. Building and combining searches • Use single quotes to capture a phrase ‘diabetes mellitus’ for example (not with Autocomplete in Quick Search) • Break up your search into individual searches, such as a drug search (in Drug Search form) and a disease search (in Disease Search form) and combine your results in Session Results • Run your cursor over your search to Edit or copy to a Search Form for guided editing. • Truncation and operators, AND, OR, NOT, NEXT, NEAR Refer to http://info.embase.com/helpfiles for more guidance and links to materials such as the Quick User Guide.
- 30. Review Question Find disease management studies for Type II diabetes •Look for your term in Emtree •Use the disease search form for disease subheadings. •Use major focus to limit your results. 30
- 31. Refining your search • Quick and Advanced Limits on Advanced, Drug and Disease Search forms • Major Focus on all advanced forms – major drugs and diseases retrieved • Field limits under Advanced Search box to search in specific fields such as article title, abstract, conference name, drug name etc • Drug and Disease Subheadings to limit to specific concepts such as Adverse Drug Reaction, Drug Comparison and Side Effect. • Filters on Session Results page for specific diseases or study types for example Check out our training videos at www.trainingdesk.elsevier.com/embase for more guidance.
- 32. More drug and disease combination searches Find recent reports of cardiac adverse effects of beta 2 agonists in asthma treatment (e.g. formoterol, salmeterol, indacaterol) 32
- 33. More drug and disease combination searches Are there any risks associated with the administration of antibiotics together with digoxin in a patient with congestive heart failure who has contracted pneumonia? 33
- 34. More drug and disease combination searches Cost effectiveness of treatment with rosuvastatin compared with other statins 34
- 35. Registering in Embase •Setting up email alerts •Saving your searches 35 •Staying up to date
- 36. Q&A
Editor's Notes
- So let’s start with tools available to you for your own training and for training others.Accesible via our info site, we have webinars, which you all know of course, being in one now. The webinar schedule or individual webinar links may be distributed throughout the organisation, in fact we positively encourage this. FAQs are not searchable yet but will be in our new platform. More on this in a minute. I will be referring to our MEDLINE in Embase White Pper later in the webinar and we have others also available.NLs are sent quarterly with tips and tricks, customer interviews and a round up of all that is new. If you have not signed up already, you can on the info site. Registered users of Embase automatically get the NL. Finally, we have a selection of short videos for the NEW user.Our information is a bit scattered at the moment and in order to optimize this, we are building a new site for release in April. You will all be notified so do not worry if you currently go somewhere for info, we will communicate in time.I would like to pause at this point and ask if you have any comments or questions on these tools? Please use the chat box we mentioned earlier. Would you like to see some additional tools? Please let me know.
- To help you and your users visualize the content in Embase, you can use this diagram. This shows the Embase content, combined with MEDLINE going back to 1960 and with Embase Classic going back to 1947. Embase AIPs. In Process and Conference Abstracts ensure users have the opportunity to review the most recent research as soon as possible. We are looking into adding MEDLINE AiPs and In Process this year.And to look at the overlap in more detail…
- All of Embase and all of MEDLINE is in Embase.com, with minimum duplication. We choose for Embase record . We will address some questions on this later.the The strategy for searching for Embase ONLY is included. This search will NOT include Medline unique and records which are overlapping Embase/MEDLINE.
- This is what we would like to demonstrate to users. By searching in Embase, they are not missing any biomedical literature, best results are achieved through using the controlled vocabulary as these are used to index the full text and the Embase tools and search capabilities help them to better pinpoint precise information. Imagine not having to read through piles of articles.
- ME: May I introduce Pierre. Pierre is a clinical liaison librarian, in the Information Services Biomedical Library, Center for Evidence-Based Research. They work with 3 main hospitals.Pierre, can you tell us more about your role and your main points of concern?PIERRE: It is many, for example, I instruct users in the use of library resources and management of information and I assist with literature searches on evidence-based practice issues, consulting with staff conducting systematic reviews with regards to search strategies. I serve as the primary library contact for many of the resources used by clinicians.My users are mainly involved in finding information from relevant and reliable sources regarding the effects of different forms of healthcare and they must be through when conducting this research and when publishing.ME: Are your users preparing articles for publication, particularly Systematic Review Articles. PIERRE: Yes and we hear more and more that journal editors and referees now stipulate that Embase searches are needed and authors publishing in the field of EBM, who need to follow Cochrane guidelines MUST conduct Embase searches. How can we best incorporate this into their workflow? Some users are still convinced that Medline is enough and some have even asked about Scopus. ME: Let’s have a look at the unique value Embase offers and also how easy it is to search with confidence!
- The PERFECT DEMO for Embase. Here we show you the answer and now let’s see how Embase helps you to get here quickly and effectively.
- One of the major steps in conducting a systematic review is a comprehensive literature search. With Embase, all users, regardless of experience may enter the best term or terms to search, even on the Quick Search page. An user with more experience may have more success with knowing which terms to use to retrieve workable results from non-thesaurus options, Google and Scopus shown here for example but what if you do not have this experience, there are no prompts like you see in Embase.
- Pubmed (Medline) does allow thesaurus searching but here also we notice a difference in the number of results retrieved. Pubmed finds 132 results compared to 8,000 in Embase. We know there is unique content in Embase, the conference abstracts shown here for, but there is also a difference in indexing focus and so Embase indexes more drugs and more deeply.
- In Medline, this article although present in Medline is not indexed with digoxin and therefore our search for digoxin and antibacterial agents did not find this article. As we know already, it is found in Embase.
- Carol was a aSenior Information Specialist from Cochrane UK when she presented Embase at MLA in 2010. She presented an update last year at MLA and this still holds true in her opinion.
- Any other questions at this point?
- A scoping search to see what is out there, then an initial search to see if their PICO question is covered - at which point they may need to adjust their PICO question. And finally a thorough expert search based on their final and strong PICO.
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- Starting with Emtree to find suitable terms/subject headings and then using Drug Search to add subheadings. Search saxagliptin with pharmacokinetics and combine with ‘type 2 diabetes mellitus’ with disease subheading ‘drug therapy’.Go back and search for dipeptidyl peptidase IV inhibitors exploded. Copy back to drug search and combine with pharmacokinetics. Combine with previous disease search.Advanced combine on the Session Results: Last search above NOT saxagliptin search, for example #2 NOT #1.
- Compare the effectiveness of sitagliptin and saxagliptin in the treatment of type II diabetes mellitus (show this in Emtree)Go to Drug Search and type in sitagliptin and saxagliptin with drug comparison. Go to Emtree and show diabetes mellitus and then go to ‘type 2 diabetes mellitus’. Take this to Disease Search and combine with disease subheading ‘drug therapy’. Combine both searches.Show editing options. NOT [review]/limAdvanced combine on the Session Results: Last search above NOT saxagliptin search, for example #2 NOT #1.Quickly show Emtree to find suitable terms/subject headings and then using Drug Search to add subheadings.
- Starting with Emtree to find suitable terms/subject headings and then using Disease Search to add subheadings. Copy Non insulin to disease search and remove original subheading. Now add disease management. Go back and add child. Experiment with major focus.Refer to www.trainingdesk.elsevier.com/embase and the Quick User Guide for more guidance
- Find disease management studies for Type II diabetesGo to Emtree and type in diabetes. Once you see the tree, select non-insulin dependant diabetes mellitus. Click on ‘take this to Disease search’. Point out ‘major focus’ option if users would like to limit their search to only records where the disease is of major importance and show on Disease Search form. Shoe quick and advanced limits.You can then add the subheading ‘disease management’. Check filters for drugs and study types.
- We shall take this review question as an example for demonstrating Embase tips. Starting with looking into finding subject headings in Emtree, using indexing and combining with filters. Antibiotic and digoxin with drug comparisonAND‘congestive heart faliure’ with drug therapyAND PneumoniaSave this search – remove drug therapy from disease and rerun main searchNow in session results, remove drug comparison from drug sub-searches and note asterix (indicates which searches have been effected by a change to a related search)– now click on result number to update your search strategy.
- Don’t loose those important searches, register in Embase so you may save your searches or set up email alerts. Registering also means you receive all up to date information such as upcoming webinars.Antibiotic and digoxin with drug combinationANDCongestive heart failure with drug therapyAND PneumoniaSave this search – remove drug therapy from disease and rerun main searchNow in session results, remove drug comparison from drug sub-searches and note asterix (indicates which searches have been effected by a change to a related search)– now click on result number to update your search strategy.Re-use a named search in a new search. For example you may have a group of #limitstrial AND digoxin