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Practicing Up To 
Date Medicine 
An overview of things that can 
make it easier 
Andrew Milne, NHS Librarian
Today we’ll cover: 
• What the Library can offer you 
• What NHS OpenAthens offers you 
• How to use those services as part of the 
Evidence Based Medicine cycle 
• Sources of additional support
Working at Imperial College 
Healthcare NHS Trust means 
access to an Imperial College 
network of libraries. 
That’s the book stock of six 
libraries instead of just one 
hospital library.
Opening hours vary by site 
Hammersmith 
9am – 9pm Monday to Friday 
Plus out of hours access to PCs 
until midnight and on weekends
Opening hours vary by site 
Charing Cross 
9am – 9pm Monday to Friday 
Plus 10am – 5pm Saturdays
Opening hours vary by site 
St. Mary’s 
9am – 9pm Monday to Friday 
1:30pm – 5pm Saturday 
Plus access to the upper gallery 
every day from 7am til midnight
Joining is simple 
1. Show Commonwealth 
Building security your hospital 
ID to get an Imperial College 
ID card. 
2. Fill in a registration form at 
the library.
Now that you’ve 
joined you get: 
books e-books 
journals e-journals 
printing and copying quiet study space 
PC access 
group study rooms 
databases free interlibrary loans 
help and training from library staff
We offer thousands of books covering 
general medicine, medical specialisms, 
nursing, allied health, and research skills.
Central Library also has books on other 
topics, including fiction.
We arrange our books 
based on NLM – National 
Library of Medicine 
classification. 
This means books 
are grouped by 
subject at general 
and specific levels.
We arrange our books 
based on NLM – National 
Library of Medicine 
classification. 
This means books 
are grouped by 
subject at general 
and specific levels.
WJ = general subject 
39 = specific subject 
OXF = title or first author
The library website has a 
dedicated section for NHS users. 
This offers information and links 
to a variety of resources and 
services.
You can also search the 
catalogue for books and 
journals or specific journal 
articles directly from library 
web pages.
For the most up to date current awareness 
and primary sources of evidence, you 
should be looking at journal articles.
We keep some current issues of journals in 
the library, with older issues available on 
request. 
Many are now provided electronically 
instead and can be viewed at one of our 
PCs.
As well as journal articles, our PCs give you 
access to: 
Internet 
Microsoft Office 
Additional resources 
from Imperial College 
London – for example 
UpToDate
You can send work to the 
B&W or colour printer from 
our PCs and release it from 
a printer with your Imperial 
College card if it has credit. 
Scanning is free.
OpenAthens 
and why it’s a vital tool 
for any health 
professional
OpenAthens gives you 
access to a wide range of 
resources – from any 
device, anywhere.
You can self-register for 
OpenAthens online – if 
necessary, we’ll check and 
approve your account.
NICE Evidence search is quick 
and handy ‘Google’ for health 
queries. 
Use it to search for clinical knowledge 
summaries, guidelines, care 
pathways, and more.
The A-Z list of journals gives you access to 
the archives of a variety of journals – at the 
library, the hospital, at home, and on the go. 
Great when you 
have a specific 
journal or article in 
mind.
The Cochrane Library 
A library of meta-analyses and systematic 
reviews available through NICE Evidence 
website. 
Systematic 
reviews = the 
gold standard
HDAS is the jewel in NICE 
Evidence’s crown. 
Healthcare Databases Advanced Search 
gives you 8 databases to search for 
articles specific to your clinical or research 
query.
The Evidence 
Based Medicine 
Cycle 
Uncertainty 
translated into 
answerable 
question 
Systematic 
retrieval of high 
quality relevant 
evidence 
Critical appraisal 
Evaluation and 
Applicable results 
applied to 
practice 
audit
Step 1 – Asking the right question 
• Be specific and provide as much detail as 
possible 
• Anticipate how you’ll use the answer 
• Consider techniques like PICO
PICO 
Population (or Patient) 
Intervention 
Control (or Comparison) 
Outcome
• Is acupuncture effective? 
VS 
• Is acupuncture an effective treatment in 
smoking cessation?
Step 2 – Gathering evidence 
• Use a variety of databases 
• Use consistent searches 
• Break your question down into ‘search 
chunks’ 
• Identify a variety of keywords and synonyms 
for each chunk
Rather than searching everything at once as in 
Google…
Use OR to combine keyword searches for 
similar and synonymous terms – i.e. to 
create chunks or groups of keywords. 
Oxygen 
therapy 
Oxygen 
delivery 
Oxygen 
inhalation 
therapy
Use OR to combine keyword searches for 
similar and synonymous terms – i.e. to 
create chunks or groups of keywords. 
Lower 
respiratory 
tract infection 
Whooping 
cough 
Pertussis
Use OR to combine keyword searches for 
similar and synonymous terms – i.e. to 
create chunks or groups of keywords. 
Child Infant Young
Use AND to combine the groups of 
keywords – bringing back only results 
relevant to every group. 
Oxygen 
therapy etc. 
Lower 
respiratory tract 
infections etc. 
Child etc.
How this looks in practice…
Map to thesaurus
Map to thesaurus
• Use your own keywords 
• Use keywords you identify in relevant 
literature 
• Use ‘map to thesaurus’ to search the 
database’s indexing system
• Constantly re-evaluate and develop your 
search strategies. 
• Don’t fall into the Google trap!
You’re not doing a quick Google 
search (or searching for pizza)
Step 3 – Critical Appraisal 
“the process of carefully and systematically 
examining research to judge its 
trustworthiness, and its value and relevance 
in a particular context” 
(Critical Appraisal 
Support Programme) 
www.casp-uk.net
Critical Appraisal… 
…stops you being a passive reader; 
…helps you to filter out low quality evidence; 
…should lead to stronger research output as 
you become aware of what makes evidence 
robust.
Step 3 – Critical Appraisal 
• Use checklists by organisations like CASP 
• Maintain a critical eye 
• Does the study ask a clear question? 
• Is the study well-designed for what it tries to 
investigate? 
• Is it statistically significant? 
• Is it clinically and locally significant?
Research design and methodology 
• Is the study type appropriate? 
• Is it ethical? 
• Was blinding used? 
• Were participants randomised? 
• Was intention to treat analysis used? 
• How many participants were lost to follow-up? 
• Was collection of results consistent?
Results 
• How large was the treatment effect? 
• Is the primary outcome clearly specified? 
• What results were found for each 
outcome? 
• How precise is the estimate of the 
treatment effect? (confidence intervals; 
power calculations)
Favours Treatment 
Value of no effect 
Favours Control 
-4 -3 -2 -1 0 1 2 3 4 
95% confidence interval
Stats cheat sheet 
• Look for p-values of 0.05 or less 
• Power calculations in the range 80-95% 
• Shorter confidence intervals mean closer 
pinpointing of the true result 
• Confidence intervals that cross 0 mean an 
inconclusive result 
• Number needed to treat (NNT) – lower is better, 
but avoid 0 or negative! 
• Relative Risk: 1 means no difference in risk 
between groups; either side favours one or the 
other
Implications of research 
• Can it be applied locally? 
• Costs and harm versus benefits? 
• Statistical significance does not mean 
clinical significance 
• Is further research needed? 
• Any conflicts of interest? 
• Any weasel words? (“approaching 
statistical significance”)
Three Rs 
• RIGOUR 
• RESULTS 
• RELEVANCE
• Join or set up a journal club 
• Follow journal clubs online (e.g. #TwitJC) 
• Attend a critical appraisal workshop 
• Read new literature  
• Save searches in HDAS and create alerts for 
when new literature is published
Steps 4 & 5 
• Applying the relevant results to your practice is 
up to you and your colleagues 
• Evaluation and audit makes continued use of 
your information skills and critical skills 
• Remain reflective and don’t rely on received 
wisdom or assume you’ve perfected something 
• Return to step 1
The Evidence 
Based Medicine 
Cycle 
Uncertainty 
translated into 
answerable 
question 
Systematic 
retrieval of high 
quality relevant 
evidence 
Critical appraisal 
Evaluation and 
Applicable results 
applied to 
practice 
audit
In summary 
• The library is here for you to use – use it 
• OpenAthens is there for you to use – use it 
• Apply systematic search techniques to 
answer focused questions 
• Set up alerts for those searches 
• Critically appraise your results before 
applying to practice 
• Seek help when you need it
Library 
Induction 
Searching 
Databases 
Current 
Awareness 
Critical 
Appraisal 
The four modules of the Library’s 
information skills training programme
Library 
Induction 
Searching 
Databases 
Current 
Awareness 
Critical 
Appraisal 
The four modules of the Library’s 
information skills training programme 
You might be able to skip steps if you feel 
comfortable. The goal is to help you complete the 
programme with the foundations necessary to make 
effective use of resources with stronger information 
literacy.
Library InductionSearching Databases 
Critical Appraisal Text here 
Social 
Media? 
Reference 
Management? 
Current 
Awareness 
New 
Tech? 
But eventually… 
• Additional modules 
• New content 
• A growing set of key 
skills for you to pick 
and mix 
• Consistent delivery 
• Fresh training 
responding to your 
needs and wants
Thanks for listening! 
Get in touch: 
a.milne@imperial.ac.uk 
020 3313 2189

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Practicing up-to-date-medicine

  • 1. Practicing Up To Date Medicine An overview of things that can make it easier Andrew Milne, NHS Librarian
  • 2. Today we’ll cover: • What the Library can offer you • What NHS OpenAthens offers you • How to use those services as part of the Evidence Based Medicine cycle • Sources of additional support
  • 3. Working at Imperial College Healthcare NHS Trust means access to an Imperial College network of libraries. That’s the book stock of six libraries instead of just one hospital library.
  • 4.
  • 5. Opening hours vary by site Hammersmith 9am – 9pm Monday to Friday Plus out of hours access to PCs until midnight and on weekends
  • 6. Opening hours vary by site Charing Cross 9am – 9pm Monday to Friday Plus 10am – 5pm Saturdays
  • 7. Opening hours vary by site St. Mary’s 9am – 9pm Monday to Friday 1:30pm – 5pm Saturday Plus access to the upper gallery every day from 7am til midnight
  • 8. Joining is simple 1. Show Commonwealth Building security your hospital ID to get an Imperial College ID card. 2. Fill in a registration form at the library.
  • 9. Now that you’ve joined you get: books e-books journals e-journals printing and copying quiet study space PC access group study rooms databases free interlibrary loans help and training from library staff
  • 10. We offer thousands of books covering general medicine, medical specialisms, nursing, allied health, and research skills.
  • 11. Central Library also has books on other topics, including fiction.
  • 12. We arrange our books based on NLM – National Library of Medicine classification. This means books are grouped by subject at general and specific levels.
  • 13. We arrange our books based on NLM – National Library of Medicine classification. This means books are grouped by subject at general and specific levels.
  • 14. WJ = general subject 39 = specific subject OXF = title or first author
  • 15. The library website has a dedicated section for NHS users. This offers information and links to a variety of resources and services.
  • 16. You can also search the catalogue for books and journals or specific journal articles directly from library web pages.
  • 17.
  • 18. For the most up to date current awareness and primary sources of evidence, you should be looking at journal articles.
  • 19. We keep some current issues of journals in the library, with older issues available on request. Many are now provided electronically instead and can be viewed at one of our PCs.
  • 20. As well as journal articles, our PCs give you access to: Internet Microsoft Office Additional resources from Imperial College London – for example UpToDate
  • 21. You can send work to the B&W or colour printer from our PCs and release it from a printer with your Imperial College card if it has credit. Scanning is free.
  • 22. OpenAthens and why it’s a vital tool for any health professional
  • 23. OpenAthens gives you access to a wide range of resources – from any device, anywhere.
  • 24. You can self-register for OpenAthens online – if necessary, we’ll check and approve your account.
  • 25. NICE Evidence search is quick and handy ‘Google’ for health queries. Use it to search for clinical knowledge summaries, guidelines, care pathways, and more.
  • 26. The A-Z list of journals gives you access to the archives of a variety of journals – at the library, the hospital, at home, and on the go. Great when you have a specific journal or article in mind.
  • 27. The Cochrane Library A library of meta-analyses and systematic reviews available through NICE Evidence website. Systematic reviews = the gold standard
  • 28. HDAS is the jewel in NICE Evidence’s crown. Healthcare Databases Advanced Search gives you 8 databases to search for articles specific to your clinical or research query.
  • 29. The Evidence Based Medicine Cycle Uncertainty translated into answerable question Systematic retrieval of high quality relevant evidence Critical appraisal Evaluation and Applicable results applied to practice audit
  • 30. Step 1 – Asking the right question • Be specific and provide as much detail as possible • Anticipate how you’ll use the answer • Consider techniques like PICO
  • 31. PICO Population (or Patient) Intervention Control (or Comparison) Outcome
  • 32. • Is acupuncture effective? VS • Is acupuncture an effective treatment in smoking cessation?
  • 33. Step 2 – Gathering evidence • Use a variety of databases • Use consistent searches • Break your question down into ‘search chunks’ • Identify a variety of keywords and synonyms for each chunk
  • 34. Rather than searching everything at once as in Google…
  • 35. Use OR to combine keyword searches for similar and synonymous terms – i.e. to create chunks or groups of keywords. Oxygen therapy Oxygen delivery Oxygen inhalation therapy
  • 36. Use OR to combine keyword searches for similar and synonymous terms – i.e. to create chunks or groups of keywords. Lower respiratory tract infection Whooping cough Pertussis
  • 37. Use OR to combine keyword searches for similar and synonymous terms – i.e. to create chunks or groups of keywords. Child Infant Young
  • 38. Use AND to combine the groups of keywords – bringing back only results relevant to every group. Oxygen therapy etc. Lower respiratory tract infections etc. Child etc.
  • 39. How this looks in practice…
  • 40.
  • 43.
  • 44. • Use your own keywords • Use keywords you identify in relevant literature • Use ‘map to thesaurus’ to search the database’s indexing system
  • 45. • Constantly re-evaluate and develop your search strategies. • Don’t fall into the Google trap!
  • 46. You’re not doing a quick Google search (or searching for pizza)
  • 47. Step 3 – Critical Appraisal “the process of carefully and systematically examining research to judge its trustworthiness, and its value and relevance in a particular context” (Critical Appraisal Support Programme) www.casp-uk.net
  • 48. Critical Appraisal… …stops you being a passive reader; …helps you to filter out low quality evidence; …should lead to stronger research output as you become aware of what makes evidence robust.
  • 49. Step 3 – Critical Appraisal • Use checklists by organisations like CASP • Maintain a critical eye • Does the study ask a clear question? • Is the study well-designed for what it tries to investigate? • Is it statistically significant? • Is it clinically and locally significant?
  • 50. Research design and methodology • Is the study type appropriate? • Is it ethical? • Was blinding used? • Were participants randomised? • Was intention to treat analysis used? • How many participants were lost to follow-up? • Was collection of results consistent?
  • 51. Results • How large was the treatment effect? • Is the primary outcome clearly specified? • What results were found for each outcome? • How precise is the estimate of the treatment effect? (confidence intervals; power calculations)
  • 52. Favours Treatment Value of no effect Favours Control -4 -3 -2 -1 0 1 2 3 4 95% confidence interval
  • 53. Stats cheat sheet • Look for p-values of 0.05 or less • Power calculations in the range 80-95% • Shorter confidence intervals mean closer pinpointing of the true result • Confidence intervals that cross 0 mean an inconclusive result • Number needed to treat (NNT) – lower is better, but avoid 0 or negative! • Relative Risk: 1 means no difference in risk between groups; either side favours one or the other
  • 54. Implications of research • Can it be applied locally? • Costs and harm versus benefits? • Statistical significance does not mean clinical significance • Is further research needed? • Any conflicts of interest? • Any weasel words? (“approaching statistical significance”)
  • 55. Three Rs • RIGOUR • RESULTS • RELEVANCE
  • 56. • Join or set up a journal club • Follow journal clubs online (e.g. #TwitJC) • Attend a critical appraisal workshop • Read new literature  • Save searches in HDAS and create alerts for when new literature is published
  • 57.
  • 58. Steps 4 & 5 • Applying the relevant results to your practice is up to you and your colleagues • Evaluation and audit makes continued use of your information skills and critical skills • Remain reflective and don’t rely on received wisdom or assume you’ve perfected something • Return to step 1
  • 59. The Evidence Based Medicine Cycle Uncertainty translated into answerable question Systematic retrieval of high quality relevant evidence Critical appraisal Evaluation and Applicable results applied to practice audit
  • 60. In summary • The library is here for you to use – use it • OpenAthens is there for you to use – use it • Apply systematic search techniques to answer focused questions • Set up alerts for those searches • Critically appraise your results before applying to practice • Seek help when you need it
  • 61. Library Induction Searching Databases Current Awareness Critical Appraisal The four modules of the Library’s information skills training programme
  • 62. Library Induction Searching Databases Current Awareness Critical Appraisal The four modules of the Library’s information skills training programme You might be able to skip steps if you feel comfortable. The goal is to help you complete the programme with the foundations necessary to make effective use of resources with stronger information literacy.
  • 63. Library InductionSearching Databases Critical Appraisal Text here Social Media? Reference Management? Current Awareness New Tech? But eventually… • Additional modules • New content • A growing set of key skills for you to pick and mix • Consistent delivery • Fresh training responding to your needs and wants
  • 64.
  • 65. Thanks for listening! Get in touch: a.milne@imperial.ac.uk 020 3313 2189