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Impact of PED in growing pigs 
Julio Alvarez, Javier Sarradell, 
Robert Morrison, Andres Perez 
DVM, PhD 
Department of Veterinary Population Medicine 
College of Veterinary Medicine 
University of Minnesota
PED impact 
a 
• Primarily due to losses in suckling piglets 
– Mortalities between 50-80%b 
– Time to recover baseline production of 
>10 wksc 
• Further impact? 
– Infected growing pigs: 1-3% mortalityb 
– Pigs exposed to PED as piglets that make it to the 
growing phase? 
a Swine enteric Coronavirus disease testing summary report, Sept 3 2014 
b White Paper (Geiger and Connor, 2013) 
c Swine Health Monitoring Project (Goede and Morrison, 2014)
Objective 
• To quantify the impact of PEDv infection 
in growing pigs by comparing 
– Mortality 
– Average daily gain (ADG) 
– Average daily feed intake (ADFI) 
– Feed conversion rate (FCR) 
in batches exposed/unexposed to the virus
Peek at the results 
• Impaired performance of pigs from 
first PED+ batches compared with 
PED- pigs 
– Increased mortality (6-18%) 
– Decreased ADG (0.07-0.26 lb/day) 
– Increased FCR (0.3-0.8)
Material and methods 
• Screening of productive records to select 
batches from positive flows 
– Only nursery/WF batches 
• Selection of 33 flows 
– 11 nursery 
– 22 WF 
Commercial sow 
Nursery 
Finishing 
Wean to 
finish 
PED detection
Inclusion criteria 
• Selection of first PED+ batch within a given flow 
(“infected” batch) 
• Selection of the closest preceding PED- batch 
from the same flow (“control” batch) 
– At least 14 days before the infected batch (increase 
specificity) 
– Not more than 4 months before the infected batch 
PED+ 
batch 
Control batch (closest available) 
Weeks
Data analysis 
• Pairs of batches - paired non-parametric 
comparison (Wilcoxon test) of 
performance records 
• Comparison of nursery to WF paired 
differences (Mann-Whitney test)
Study population 
• 18 flows fulfilled the inclusion criteria (18 case + 18 
control batches) 
– 4 nursery 
– 14 WF (double stocking: first stage in growing, ≈60d) 
• Average mortality, ADG, ADFI and FCR in the previous 
four months (before PED) within normal limits
Descriptive results 
• First PED+ batch  change in trends 
– Increase in mortality (4.9 to 15.2%) 
– Decrease in ADG (0.79 to 0.72) 
– No change in ADFI 
– Increase in FCR (1.75 to 2.28) 
• GRAFICA GLOBAL 
4 3 2 1 PED!
Paired comparison 
• Mortality 
12.5% increase 
(95% CI: 6.4-18.4) 
Control Infected
• Performance 
ADG ADFI 
FCR 
↓0.16 lb/d 
↑ 0.55 
Control Infected Control Infected Control Infected
So, as previously mentioned… 
• Impaired performance of pigs from 
first PED+ batches compared with 
PED- pigs 
– Increased mortality (6-18%) 
– Decreased ADG (0.07-0.26 lb/day) 
– Increased FCR (0.3-0.8)
Conclusions (II) 
• Caveats of the study 
– Reduced dataset 
– No adjustment by covariates (site) 
• However… 
– Robust trend suggesting a decreased performance of 
growing pigs from PED+ batches 
• Increase in mortality (6-18%... Or more!) 
• Decrease in ADG, ADFI unaffected Increase in FCR (0.3-0.8) 
– Rough numbers: with 0.3$/lb feed from wean to 40 lbs, 
0.55 poorer FCR costs approx $0.16/lb gain 
• Impact of PEDv goes beyond suckling piglets
Dr. Sarradell 
Dr. Morrison 
Questions? 
jalvarez@umn.edu 
Dr. Perez

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Dr. Julio Alverez - Impact of PED in Growing Pigs

  • 1. Impact of PED in growing pigs Julio Alvarez, Javier Sarradell, Robert Morrison, Andres Perez DVM, PhD Department of Veterinary Population Medicine College of Veterinary Medicine University of Minnesota
  • 2. PED impact a • Primarily due to losses in suckling piglets – Mortalities between 50-80%b – Time to recover baseline production of >10 wksc • Further impact? – Infected growing pigs: 1-3% mortalityb – Pigs exposed to PED as piglets that make it to the growing phase? a Swine enteric Coronavirus disease testing summary report, Sept 3 2014 b White Paper (Geiger and Connor, 2013) c Swine Health Monitoring Project (Goede and Morrison, 2014)
  • 3. Objective • To quantify the impact of PEDv infection in growing pigs by comparing – Mortality – Average daily gain (ADG) – Average daily feed intake (ADFI) – Feed conversion rate (FCR) in batches exposed/unexposed to the virus
  • 4. Peek at the results • Impaired performance of pigs from first PED+ batches compared with PED- pigs – Increased mortality (6-18%) – Decreased ADG (0.07-0.26 lb/day) – Increased FCR (0.3-0.8)
  • 5. Material and methods • Screening of productive records to select batches from positive flows – Only nursery/WF batches • Selection of 33 flows – 11 nursery – 22 WF Commercial sow Nursery Finishing Wean to finish PED detection
  • 6. Inclusion criteria • Selection of first PED+ batch within a given flow (“infected” batch) • Selection of the closest preceding PED- batch from the same flow (“control” batch) – At least 14 days before the infected batch (increase specificity) – Not more than 4 months before the infected batch PED+ batch Control batch (closest available) Weeks
  • 7. Data analysis • Pairs of batches - paired non-parametric comparison (Wilcoxon test) of performance records • Comparison of nursery to WF paired differences (Mann-Whitney test)
  • 8. Study population • 18 flows fulfilled the inclusion criteria (18 case + 18 control batches) – 4 nursery – 14 WF (double stocking: first stage in growing, ≈60d) • Average mortality, ADG, ADFI and FCR in the previous four months (before PED) within normal limits
  • 9. Descriptive results • First PED+ batch  change in trends – Increase in mortality (4.9 to 15.2%) – Decrease in ADG (0.79 to 0.72) – No change in ADFI – Increase in FCR (1.75 to 2.28) • GRAFICA GLOBAL 4 3 2 1 PED!
  • 10. Paired comparison • Mortality 12.5% increase (95% CI: 6.4-18.4) Control Infected
  • 11. • Performance ADG ADFI FCR ↓0.16 lb/d ↑ 0.55 Control Infected Control Infected Control Infected
  • 12. So, as previously mentioned… • Impaired performance of pigs from first PED+ batches compared with PED- pigs – Increased mortality (6-18%) – Decreased ADG (0.07-0.26 lb/day) – Increased FCR (0.3-0.8)
  • 13. Conclusions (II) • Caveats of the study – Reduced dataset – No adjustment by covariates (site) • However… – Robust trend suggesting a decreased performance of growing pigs from PED+ batches • Increase in mortality (6-18%... Or more!) • Decrease in ADG, ADFI unaffected Increase in FCR (0.3-0.8) – Rough numbers: with 0.3$/lb feed from wean to 40 lbs, 0.55 poorer FCR costs approx $0.16/lb gain • Impact of PEDv goes beyond suckling piglets
  • 14. Dr. Sarradell Dr. Morrison Questions? jalvarez@umn.edu Dr. Perez