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Medical Management of Eating
          Disorder
       Dr. Dawn Holemon
Diagnostic Assessment
• Psychiatric       • Anorexia nervosa
                    • Bulimia nervosa
                    • ED, nos



• Medical           • Risk increased with rapid
                      weight change, purging,
                      onset of binges, non
                      compliance with medication
AN, BN or ED, nos
• Refer for inpatient or residential care
  Pregnancy
  Diabetes mellitus
  Abnormal EKG
  Deficiencies of potassium, magnesium or phosphorus
  Suicidal ideation
EKG
Associated disorders
• Medical
PANDAS
PCOS
Associated disorders
• Psychiatric
Major depression
Anxiety disorder
Bipolar disorder
Alcohol and/or drug dependence or abuse
Body dysmorphic disorder
Laboratory tests commonly indicated
         in eating disorder


Liver enzymes              RBC Folate
Blood count                Magnesium,
Serum creatinine,            Phosphorus, Amylase,
   ferritin, vitamin B12     Potassium, Sodium
                           TSH
Laboratory tests commonly indicated
         in eating disorder


Urinalysis
Urine drug screen
EKG
Bone density
Medical complications of eating
          disorder

Edema
Weakness
Shortness of breath
Cardiac arrhythmias
Chest pain
Confusion
Loss of consciousness
Medical complications of eating
             disorder
Refeeding syndrome

 -imbalance of electrolytes and fluid
 -risk factors
 -symptoms to monitor
Psychotropic medications used to
      treat eating disorder


  SSRI          Other antidepressant
  SNRI          Trimonoamine
  TCA              modulator
  MAOI
Psychotropic medications used to
         treat eating disorder
Mood stabilizers
Antipsychotics, 1st generation
Antipsychotics, 2nd generation
Psychotropic medications used to
         treat eating disorder
Anxiolytics, non benzodiazepine
Benzodiazepines, short-acting
Benzodiazepines, mid-acting
Benzodiazepines, long-acting
Psychotropic medications used to
         treat eating disorder
Insomnia
ADHD
Dependence, opioid
Dependence, nicotine
Common side effects of medications
    used to treat eating disorder


Lightheadedness   Headache
Sedation          Acid reflux
Dry mouth         nausea
Constipation
Less common side effects of
medication used to treat eating
           disorder
 Parasthesia
 EPSE
 Weight gain/loss
 Galactorrhea
Recent research in neuropsychiatry

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Dr. holemon- Medical Management of ED

Editor's Notes

  1. Diagnosis of ED; anorexia, bulimia or ED, nos Concurrent psychiatric diagnosis, history of prior treatment, medications, onset of illness Medical; preadmission labs, EKG, bone density; ROS, past medical history, FH Cardiac arrhythmia is the most common medical cause of death in AN
  2. Chest pain, dysrhythmias, syncope
  3. Strength of association of substance use disorders varies by diagnosis, strongest in bulimia, weaker in ED of AN, purging type, not significant in AN, restricting Substance use increased suicide risk across the board, all psychiatric diagnoses
  4. Refeeding at low energy replacement and monitor electrolytes, weight, cardiac status Rapid weight loss and/or profound weight loss; abnormal EKG; low phosphorus levels Symptoms; swelling, SOB, altered mental status
  5. SNRI examples TCA uses MAOI issues and complications Other antidepressant examples TMM example; deplin or methylfolate as booster