Research View of Porcine Epidemic Diarrhea Virus - Dr. Bong Kyun Park, Professor and Swine Virologist, Veterinary Virology Laboratory, Seoul National University, from the 2013 Allen D. Leman Swine Conference, September 14-17, 2013, St. Paul, Minnesota, USA.
More presentations at http://www.swinecast.com/2013-leman-swine-conference-material
Recent advances in African swine fever vaccine development at the Internation...ILRI
Presentation by Lucilla Steinaa at a Global African Swine Fever Research Alliance (GARA)/International Alliance for Biological Standardization (IABS) webinar on current efforts in African swine fever vaccines, 6 May 2021
Recent advances in African swine fever vaccine development at the Internation...ILRI
Presentation by Lucilla Steinaa at a Global African Swine Fever Research Alliance (GARA)/International Alliance for Biological Standardization (IABS) webinar on current efforts in African swine fever vaccines, 6 May 2021
Dr. X.J. Meng - Designing PRRSV Vaccines for Heterologous ProtectionJohn Blue
Designing PRRSV Vaccines for Heterologous Protection - Dr. X.J. Meng, VA-MD College of Veterinary Medicine, Virginia Tech, from the 2015 North American PRRS Symposium, December 4 - 5, 2015, Chicago, IL, USA.
More presentations at http://www.swinecast.com/2015-north-american-prrs-symposium
Dr. Michael Murtaugh and Dr. Cheryl Dvorak - Natural Infection, Immunity & Pr...John Blue
Natural Infection, Immunity & Prevalence of PCV2 - Dr. Michael Murtaugh and Dr. Cheryl Dvorak, University of Minnesota, USA , from the Boehringer Ingelheim Pre-AASV Conference, February 28, 2014 - Dallas, TX
More presentations at http://www.swinecast.com/2014-boehringer-ingelheim-aasv
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Dr. Hanchun Yang - Pathogenesis and control of Chinese highly pathogenic Porc...John Blue
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More presentations at http://www.swinecast.com/2016-north-american-prrs-symposium
Dr Paul Bowyer - Aspergillosis Study Day May 1st 2012Graham Atherton
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Dr. X.J. Meng - Designing PRRSV Vaccines for Heterologous ProtectionJohn Blue
Designing PRRSV Vaccines for Heterologous Protection - Dr. X.J. Meng, VA-MD College of Veterinary Medicine, Virginia Tech, from the 2015 North American PRRS Symposium, December 4 - 5, 2015, Chicago, IL, USA.
More presentations at http://www.swinecast.com/2015-north-american-prrs-symposium
Dr. Michael Murtaugh and Dr. Cheryl Dvorak - Natural Infection, Immunity & Pr...John Blue
Natural Infection, Immunity & Prevalence of PCV2 - Dr. Michael Murtaugh and Dr. Cheryl Dvorak, University of Minnesota, USA , from the Boehringer Ingelheim Pre-AASV Conference, February 28, 2014 - Dallas, TX
More presentations at http://www.swinecast.com/2014-boehringer-ingelheim-aasv
Presented by José M. Sánchez-Vizcaíno at the African Swine Fever Diagnostics, Surveillance, Epidemiology and Control Workshop, Nairobi, Kenya, 20-21 July 2011
Dr. Hanchun Yang - Pathogenesis and control of Chinese highly pathogenic Porc...John Blue
Pathogenesis and control of Chinese highly pathogenic Porcine Reproductive & Respiratory Syndrome (PRRSV) - Dr. Hanchun Yang, China Agricultural University, from the 2016 North American PRRS Symposium, December 3‐4, 2016, Chicago, Illinois, USA.
More presentations at http://www.swinecast.com/2016-north-american-prrs-symposium
Dr Paul Bowyer - Aspergillosis Study Day May 1st 2012Graham Atherton
Dr Paul Bowyer is the Principle Scientist at the National Aspergillosis Centre. This talk was given to a group of professionals allied to medicine who are attending an education & awareness day at the Centre.
Dr Bowyer summarises our current understanding of the pathogenic processes that lead to an aspergillus infection.
Respiratory pathogens in an intensive poultry farm in Debre Zeit, EthiopiaILRI
Poster prepared by S. Hutton, J. Bettridge, T. Habte, R. Christley , E. Sambo and K. Ganapathy for the Annual Meeting of the Society of Veterinary Epidemiology and Preventive Medicine, Madrid, Spain, 20-22 March 2013.
Gene Olinger, USAMRIID, Fort Detrick USA, presents at the ProImmune Antigen Characterization and Biomarker Discovery Summit, January 2011.
Protective Immune Reponses to Ebola Virus
The effect of concurrent vaccine administration for peste des petits ruminant...ILRI
Poster by Alex Mabirizi, Joseph Nkamwesiga, Paul Lumu, Kristina Roesel, Charles Drago Kato and Henry Kiara presented at the Boosting Uganda's Investment in Livestock Development (BUILD) project annual planning meeting, Kampala, Uganda, 20–22 September 2022.
Dr. Matt Sturos - Senecavirus A Infection in BoarsJohn Blue
Senecavirus A Infection in Boars - Dr. Matt Sturos, from the 2017 Allen D. Leman Swine Conference, September 16-19, 2017, St. Paul, Minnesota, USA.
More presentations at http://www.swinecast.com/2017-leman-swine-conference-material
Peste des-ruminants-is-a-rinderpest.doc pdfGudyne Wafubwa
Peste des petits ruminant virus (PPRV) is a disease mostly affecting goats and sheep. Since its first discovery, it has caused massive economic loss to most small pastoralists in Africa and other developing countries. It is the integral role of all stakeholders to join hands so as to eradicate the disease.
Prevalence of Moraxella ovis Infection in Goats under the Ladang Angkat Progr...iosrjce
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS) is a double blind peer reviewed International Journal edited by the International Organization of Scientific Research (IOSR). The journal provides a common forum where all aspects of Agricultural and Veterinary Sciences are presented. The journal invites original papers, review articles, technical reports and short communications containing new insight into any aspect Agricultural and Veterinary Sciences that are not published or not being considered for publication elsewhere.
Clinical Manifestations of Plasmodium bergheiANKA Infection in Juvenile Mice:...AI Publications
Malaria is an important health and development challenge in Africa, Animalmodels most particularly mice, have long been employedto study malaria pathogenesis. Clinical manifestations due to Plasmodium bergheiANKA infection in juvenile mice as a model for understanding the complications ofcongenital malaria in neonates.Forty-five juvenile mice (5-7 days old) were acquired from University College Hospital, Ibadan and injected with 2 x 107 (0.2ml) Plasmodium berghei ANKA parasitized red blood cells (PRBCs). Mice were transported to the study site, kept in well ventilated cages and fed daily with a balanced ration. Every day after post-P. berghei infection, mice were monitored for mortality. Clinical manifestations ofexperimental cerebral malaria (ECM) was assessed and confirmed if at leastruffled fur, hunching, wobbly gait, limb paralysis, convulsions, or coma was observed. Each sign was given a score of 1. Animals with scores ≥4 were considered to have severe ECM.20 (44%) micewerelost due to natural cause (i.e. stress) at day 2 of the experiment. Between day 4 and 9, 25 (56%) of the studymice presented clinical signs of ECM which includes; ruffled fur 25(100%), hunching 21 (84%), wobbly gait 17 (68%), limb paralysis 20 (80%), convulsions 25 (100%) and subsequently died. Survival rate and severity of ECM in the mice differs, 22 (88.0%) had severe ECM and 3(12.0%) had mild ECM.This study has shown that parasite establishment and malaria complications can manifest as early as 4 days’postP. berghei infection in 5-7 days old mice.
Rotavirus RV is a disease that is extremely spreadable in children whose age ranges between 3'5 years. Rotavirus vaccination RVV is an effective method for combating the diarrhoea disease as rotavirus is the leading cause of diarrhoea worldwide. For fulfilling the aim of reducing the burden of RV caused in children under 5 years for diarrhoea mortality. World Health Organization WHO recommends introducing RVVs worldwide. Globally three RVVs are licensed for local use two monovalent vaccines Rotarix, and Rotavac and a pentavalent vaccine RotaTeq. Safety and efficacy of these vaccines have been proved, however, they require cold chain storage at or below 2oto 8oC before use. In this article, a detailed profile of Rotarix vaccine is being emphasized. Rotavirus Vaccines are in high demand for introduction by many low income countries, but limitations such as price, poor supply and insufficient cold chain capacity at distant delivery points, have restricted their introduction. A. A Bhosale | Dr. V. U Barge "Illustrative Review on Rotavirus Vaccines" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-1 , December 2019, URL: https://www.ijtsrd.com/papers/ijtsrd29552.pdfPaper URL: https://www.ijtsrd.com/biological-science/biotechnology/29552/illustrative-review-on-rotavirus-vaccines/a-a-bhosale
Occurrence of selected bacterial and viral pathogens in smallholder pig produ...ILRI
Poster prepared by Michel Dione (ILRI), Charles Masembe (Makerere University), Joyce Akol (Makerere University), Joseph Kungu (National Livestock Resources Research Institute, Uganda), Winfred Amia (ILRI) and Barbara Wieland (ILRI) for the Joint International Conference of the Association of Institutions for Tropical Veterinary Medicine and the Society of Tropical Veterinary Medicine, Berlin, 4–8 September 2016
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OACI Farmer Certification Program - Jordan Hoewischer, Ohio Farm Bureau, from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
Fred Yoder - No-till and Climate Change: Fact, Fiction, and IgnoranceJohn Blue
No-till and Climate Change: Fact, Fiction, and Ignorance - Fred Yoder, Former President, National Corn Growers Association, from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
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Fifty Years Of No-till Research In Kentucky - Dr. John Grove, Univerity of Kentucky, from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
Dr. Warren Dick - Pioneering No-till Research Since 1962John Blue
Pioneering No-till Research Since 1962 - Dr. Warren Dick, OSU-OARDC (retired), from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
Dr. Christine Sprunger - The role that roots play in building soil organic ma...John Blue
The role that roots play in building soil organic matter and soil health - Dr. Christine Sprunger, OSU - SENR, from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
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Stratification, the Role of Roots, and Yield Trends after 60 years of No-till - Dr. Leonardo Deiss, OSU, from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
Dr. Steve Culman - No-Till Yield Data AnalysisJohn Blue
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Setting up a Corn and Soybean Herbicide Program with Cover Crops - Dr. Jeff Stachler, OSU Extension, from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
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Dealing with Cover Crops after Preventative Planting - Jim Hoorman, Hoorman Soil Health Services, from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
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Dealing with Poor Soil Structure and Soil Compaction - Dr. Sjoerd Duiker, Extension Agronomist, Penn State University, from the 2020 Conservation Tillage and Technology Conference, held March 3-4, 2020, Ada, OH, USA.
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Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Dr. Bong Kyun Park - Research View of Porcine Epidemic Diarrhea Virus
1. Molecular genetics of recent
PEDV isolates and Understanding
the variability of PEDV
BongKyun Park
DVM, MSc, PhD
Dept. of Veterinary Microbiology
College of Veterinary Medicine
Seoul National University
Sep-16-2013
Porcine Epidemic Diarrhea Virus
5. Recent Outbreaks of PED and TGE in Korea
PED Outbreaks
Sep-16-2013
TGE Outbreaks
Porcine Epidemic Diarrhea Virus
5
6. 4 Major Swine Diseases in Korea
Classical Swine Fever(Apr. 2009)
PCV-2
PRRS
PED
Sep-16-2013
Porcine Epidemic Diarrhea Virus
6
7. Routine pattern of SN titers against PEDV
in commercial farms
SN titers(2ⁿ)
Sep-16-2013
Porcine Epidemic Diarrhea Virus
7
8. PED(Porcine Epidemic Diarrhea)
A devastating enteric disease with acute diarrhea,
vomiting, dehydration and significant mortality in
swine, incurring heavy economic losses
In many swine-raising countries, notably in Europe,
North America, southeast Asian countries including
China.
Extremely difficult to differentiate PED from TGE
clinically
The family Coronaviridae, serologically unrelated
Sep-16-2013
Porcine Epidemic Diarrhea Virus
8
16. Beginning in October 2010, the PED outbreak
overwhelmed >10 provinces in southern China,
and >1,000,000 piglets died.
Sep-16-2013
Porcine Epidemic Diarrhea Virus
16
18. Sequences of the S genes from this outbreak were 99.1%–
100.0% homologous and had 88.7%–98.9% nt identity with
all reference strains, 98.5%–98.9% with Thailand strains,
and 94.5%–95.1% with vaccine strain CV777. The partial S
gene deduced amino acid sequences were compared and
also showed a high degree of homology (98.0%–100.0%);
they had 85.3%–98.7% identity with all reference strains,
98.0%–98.7% with Thailand strains, and 93.3%–94.7%
with vaccine strain CV777.
Sep-16-2013
Porcine Epidemic Diarrhea Virus
18
20. Fig. 2 Schematic representation of the PEDV genome based on the CV777
(GenBank accession No. AF353511) strain
Sep-16-2013
Porcine Epidemic Diarrhea Virus
20
22. New variants of porcine epidemic diarrhea virus –
3 new PEDV variants were identified in vaccinated
swine herds which animals exhibited severe diarrhea
Sep-16-2013
Porcine Epidemic Diarrhea Virus
22
25. Phylogenetic analysis of the complete M gene showed that
all south China PEDV strains have a close relationship
with most of the strains in Korea and Thailand, but differ
genetically from the vaccine strain (CV777).
Sep-16-2013
Porcine Epidemic Diarrhea Virus
25
26. Phylogenetic analysis based on S1 or sM gene, which
have high levels of variations, indicated that each sample
was related to the specific reference strain, and this finding
was consistent with the protein characterization prediction
analysis.
Sep-16-2013
Porcine Epidemic Diarrhea Virus
26
37. Fecal shedding of PEDV DR13 after
oral inoculation in pigs
RT-PCR & RFLP
For up to 6 days in 3-day-old piglets,
9 days in 2-week-old pigs, and
3 days in late-term pregnant sows.
* All 3-day (n=2) and 2-week-old (n=4) piglets were inoculated with
5 mL of virus suspension, and sows (n=16) with 1 mL. Srain DR13
was harvested from intestinal mucosa of infected pigs and either
administered as a 10% suspension (parent strain; 0 passage) or
propagated in Vero cells.
Sep-16-2013
Porcine Epidemic Diarrhea Virus
37
38. Immune responses of serum samples from pregnant sows inoculated
with Vero cell attenuated PEDV DR13, using IgA-specific ELISA
(*P<0.05)
Sep-16-2013
Porcine Epidemic Diarrhea Virus
38
39. Antibody responses from serum samples against PEDV in 3-day-old
piglets using IgG and IgA-specific ELISA before challenge exposure
(*P<0.05)
Sep-16-2013
Porcine Epidemic Diarrhea Virus
39
40. Antibody responses from serum samples against PEDV in 3-day-old
piglets using the SN test before challenge exposure (*P<0.05)
Sep-16-2013
Porcine Epidemic Diarrhea Virus
40
41. RT-PCR detection of virus shedding in serial passages of
colostrum-deprived 3-day-old pigs
Level of pig passage
Pig
No.
Days after oral inoculation
0 1
5
6
7
− +/+a
+/+
+/+
+/+
+/+
+/+
−
− +/+
+/+
+/+b
Control
− −
−
−
−
−
−
−
2-A
− +/+
+/+
+/+
+/+
−
−
−
2-B
− +/+
+/+
+/+b
Control
− −
−
−
−
−
−
−
3-A
3
4
1-B
2
3
1-A
1
2
− +/+
+/+
+/+
−
−
−
−
control − −
−
−
−
−
−
−
PEDV detection in feces using RT-PCR/RFLP patterns (HindIII andXhoII) of the virus.
b
Pigs 1B and 2B were sacrificed at day 3 after oral inoculation, and small intestines collected for preparing the next
oral inoculum.
a
Sep-16-2013
Porcine Epidemic Diarrhea Virus
41
42. Survival rate (%) of piglets born from vaccinated sows
after challenge with wild-type PEDV
90
80
70
60
50
40
30
20
10
0
Oral(20/ 23)
Sep-16-2013
IM(6/ 15)
Control(14/ 14)
Porcine Epidemic Diarrhea Virus
42
43. Acknowledgements
Dr. Jin-Sik Oh, DVM, MSc, PhD
Dr. Dae-Sop Song, DVM, PhD
Dr. Seong-Jun Park, BS, PhD
Green Cross Veterinary Products Co.
Ltd
Sep-16-2013
Porcine Epidemic Diarrhea Virus
43
44. Thank you for your attention !
Cross neutralization and new vaccine candidate ???
Sep-16-2013
Porcine Epidemic Diarrhea Virus
44