Diapsids are a subclass of reptiles that first appeared during the Permian period. They are distinguished by having two openings on each side of the skull. Modern diapsids include reptiles like lizards, snakes, crocodilians, birds, and their extinct relatives. Diapsids ruled land, air, and sea during the Mesozoic era and are characterized by having two temporal fenestrae in each side of the skull which allowed for stronger jaw muscles.