This document summarizes a study that used design of experiments (DOE) to determine the optimal parameters for curing and heat treating EPDM G2 flange O-rings. A 2^4 factorial design was used to test the effects of four factors (curing temperature, curing time, heat treatment temperature, and heat treatment time) on the mechanical properties of O-rings, including tensile strength, elongation at break, and load at break. Interaction plots and ANOVA were used to analyze the results. The analysis found a significant interaction between curing temperature and curing time for elongation at break and percentage elongation, but other interactions were insignificant. The study aims to optimize the curing and heat treatment parameters to achieve