The document presents a novel congestion-aware routing algorithm for asynchronous network-on-chip designs that addresses the impact of process variation (PV) on performance metrics like saturation throughput and average message delay. It evaluates various adaptive routing algorithms to improve efficiency under different traffic patterns and introduces a low-power content-addressable memory (CAM) for enhanced data address associativity. The findings suggest that ignoring PV in routing algorithms leads to significant performance degradation, emphasizing the necessity for design strategies that account for such variations.