The document discusses dental management considerations for pregnant women. It notes that dental treatment may be modified during pregnancy if risk is properly assessed for the patient and fetus. Key changes include increased blood volume, heart rate and the potential for supine hypotensive syndrome in later stages. Treatment timing, dental radiation exposure, medications and nitrous oxide use all require special precautions. Periodontal disease is associated with preterm birth and low birth weight so maintenance is important. With proper risk assessment and positioning, dental care can be provided safely during pregnancy.

1. DENTAL MANAGEMENT OF
PREGNANT WOMEN

2.  The pregnant woman who presents for
dental care requires special
considerations to accommodate the
physiologic changes associated with
pregnancy.
 During pregnancy, dental treatment may
be modified but need not be withheld
provided that the risk assessment is made
properly for both the patient and the fetus.

3. PHYSIOLOGIC CHANGES:
Complex hormonal interactions profound
physiologic changes
Increase estrogen by 10 folds & progestron by 30
folds
Cardiovascular system:
 Increase in blood volume by an average of 30% -
40%.
 Dilutional anemia “ physiologic anemia of
pregnancy”.
 Cardiac output increases 30% - 50%.
 Heart rate increases 20% - 30%.
 Increased all coagulation factors except factors XI
& XIII decreased ( hypercoagulable state

4. SUPINE HYPOTENSIVE SYNDROME
During second & third trimesters, a decrease
in blood pressure & cardiac output can
occur while patient is in a supine position
due to decreased venous return to heart
due to compression of inferior vena cava
by the gravid uterus.

5. MANIFESTATIONS:
 Hypotension
 Tachycardia
 Sweating
 Nausea
 Weakness
 Sense of lack of air
 Possible loss of consciousness

6. Gastrointestinal system:
 Heart burn/reflux
 Nausea & vomiting

8. DENTAL CONSIDERATIONS
1. Timing of treatment
2. Dental radiation exposure
3. Use of local anesthesia
4. Prescription of drugs
5. Nitrous oxide gas administration
6. Prenatal fluoride
7. Amalgam restorations

9. TIMING OF TREATMENT
 First trimester:
unless emergency treatment is required it is advisable to defer elective
treatment because of potential vulnerability of fetus.
The baby’s organs develop during this time and are most sensitive to radiation and
chemicals.
 Second trimester: of pregnancy is the safest period for dental therapy because:
- absence of nausea & vomiting
- stable fetus
- low incidence of obstetrical complications
Periodontal maintenance and preventive care and simple restorative procedures that
will eliminate potential problems and control active disease may be performed..
 Third trimester:
- scaling and prophylaxis may be repeated to minimize hormonal gingival
changes
- elective treatment should be avoided
- short visits
- position is more upright rather than supine, and slightly rolled to left side or
place small pillow under right hip.
For pregnant patient with excessive ,uncontrolled vomiting morning appointments

10. DENTAL RADIATION EXPOSURE
 Fetus is most susceptible to radiation between 2nd
& 6th week of gestation.
 Single dental x-ray exposes patient to 0.01
millirads ( 40 times less than daily dose acquired
from cosmic radiation).
 Doses less than 5-10 rads not teratogenic.
 Therefore diagnostic dental x-ray should not be
withheld during pregnancy.
 Exposure can be limited by :
- lead apron shielding
- modern fast film
- avoiding retakes

11. PRESCRIPTION OF DRUGS
 FDA drug classification for pregnancy
Controlled studies in women fail to demonstrate a risk to the fetus
in 1st trimester & the possibility of fetal harm appears remote
(safe for use)
A
Animal studies show no risk or if risk shown in animals controlled trials
in women showed no risk
(safe for use)
B
Studies in animals with adverse effects & no human studies or no
animal or human studies but benefits of use may out weight potential
harms
(used only if benefits out weight the risks)
C
There is evidence of human fetal risk but benefits may out weight risks
(avoided with some exceptional circumstances)D
Studies in animal or human demonstrate fetal abnormalities or there is
evidence of fetal risk or both & risk out weight any benefits
(Strictly avoided during pregnancy)
X

12.  Common analgesics:
- Paracetamol (B)
- Ibuprofen (B/D)
- Aspirin (C/D) {despite being non teratogenic , it may cause maternal
& fetal hemorrhage as well as prolonged labor thus its use should be
avoided specially during 2nd & 3rd trimesters.}
 Common antibiotics:
- Penicillin (B)
- Amoxicillin (B)
- Cephaloxin (B)
- Erythromycine base (B) {not estate, as it cause cholestatic
hepatitis}
- Clindamycine (B)
- Tetracycline (D) {accumulates in bones & chelates calcium , inhibits
bone growth, discolors teeth}
- Nystatin (B)
- Chlorhexidine rinse (B)
- Metronidazole (B).
 Sedatives:
- Diazepam (D)

13. USE OF LOCAL ANAESTHETICS
 LA are in no way contraindicated for pregnant
women , however it should be remembered that all
LA agents cross the placental barrier & inter the
circulation of the fetus , so excessive amount of
LA should not be used & LA without
vasoconstrictor are more suitable.
 Lidocaine(xylocaine)
 Etidocaine (B)
 Prilocaine
 Procaine
 Bupivicaine (C)
 mepivicaine

14. NITROUS OXIDE GAS
 Safety is being debated.
 Short term exposure do not cause birth
defects or spontaneous abortion .
 Chronic exposure may result in fetal loss
& infertility.
 Literature suggests that nitrous oxide
should be avoided until more conclusive
research is available.

15. USE OF FLUORIDE
 Fluoride:
- inhibits demineralization & promotes
remineralization of early caries
- decreases acid production in plaque by
inhibiting glycolysis in cariogenic bacteria
- inhibits synthesis of extracellular
polysaccharides
- safely tolerated dose (STD) 1 mg/kg
 Topical fluoride :
has no increased risk during pregnancy.
 Pre-natal fluoride :
the placenta only allows small amount of fluoride to
cross, thus pre-natal fluoride is relatively

16. AMALGAM RESTORATIONS
Amount of mercury vapor released from
amalgam fillings about 1-3 µg/day is below
the toxic level, it is well established that
this amount is not enough to produce any
teratogenic effect.

18. PREGNANCY RELATED ORAL HEALTH PROBLEMS
1. Pregnancy gingivitis
2. Pregnancy epulis
3. Erosion
4. Dental caries
5. Tooth mobility

19. PREGNANCY GINGIVITIS
 Gingival inflammation initiated by
plaque & exacerbated by elevated
circulatory estrogen which
increases capillary permeability &
affect epithelium of gingiva.
 Estradiol & progestone are
essential growth factors for
provetella intermedia
 Occurs commonly in 2nd – 8th
months in 50% - 100% of women
 Treated by scaling , root planning

20. Gingivitis associated with pregnancy.
(a) A patient in the last trimester of pregnancy with very inflamed edematous
gingival tissue which tended to bleed with the slightest provocation.
(b) The improvement in gingival health 6 months after birth of the baby and an
intensive course of non-surgical periodontal treatment.

21. PRERAGNANCY EPULIS (GRANULOMA)
 Pedunculated fibro-granulomatous lesion develop
during pregnancy due to vascular response to
increased progestron usually at sites with pre-
existing gingivitis.
 Bright red , hyperemic & edematous lesion often
occur in anterior papillae of maxillary teeth not
exceed 2cm. In diameter , in up to 5% of women.
 Careful oral hygiene & debridement during
pregnancy are important in preventing its
occurrence.
 Treated by : - scaling & root planning
- excision if it is too large or bleeds

22. Multilobulated appearance of an early pregnancy epulis, demonstrating
vascular elements and tissue edema

23. (a) Pregnancy granuloma of gingiva before and after surgical removal and
healing (b).

24. DENTAL EROSION
 Erosion= loss of tooth
substance due to exposure to
chemical material.
 Vomiting & esophageal reflux
result in acid exposure which
cause weakening of tooth
enamel & dental erosion

25. DENTAL CARIES
 Saliva changes:
- decreased minerals
-decreasing flow in 1st & 3rd trimester
- more acidic
 Morning sickness
 uncontrolled oral hygiene
All are predisposing factors for dental caries

27. MATERNAL PERIODONTAL HEALTH & PREGNANCY
 Preterm labor:
- maternal periodontal disease is associated with
increased risk of preterm labor
- anaerobic oral gram-ve bacteria cause inflammatory
response which stimulates prostaglandin & cytokine
production to stimulate labor
 Low birth weight:
evidence is not conclusive
 Pre eclampsia:
inflammed periodontal tissues produce significant
amount of cytokines mainly interlukin 1 beta(IL1β) ,
IL6, prostaglandin E2 & tumor necrosis factor
alpha(TNFα) , were higher in women with pre
eclampsia compared with healthy matched pregnant
women
(Oettinger-Borak,2003)

28. STUDIES
o In the early 1990s, Offenbacher and his group hypothesized that oral
infections, such as periodontitis, could represent a significant source of
both infection and inflammation during pregnancy. Offenbacher noted that
periodontal disease is a Gram-negative anaerobic infection with the
potential to cause Gramnegative bacteremias in persons with periodontal
disease. He hypothesized that periodontal infections, which serve as
reservoirs for Gram-negative anaerobic organisms, lipopolysaccharide
(LPS, endotoxin) and inflammatory mediators including PGE2 and TNF-a,
may be a potential threat to the fetal-placental unit (Collins et al. 1994a,b).
o Jeffcoat and Hauth have recently confirmed this association in a larger
case-control study. Gathering data on 1313 mothers, Jeffcoat and Hauth
reported
that maternal periodontitis was an independent risk factor for preterm
birth. With increasing severity of periodontal disease as an exposure,
there was an increased risk for preterm birth with odds ratios ranging from
4.45 to 7.07 for moderate to severe periodontitis, adjusting for age, race,

29. CONCLUSION
 Establishing a healthy oral environment is the most important objective in
planning the dental care of pregnant patient.
 This objective is achieved by adequate plaque control, comprising tooth
brushing, flossing and professional prophylaxis.
 A consultation with a physician is necessary specially in cases of disturbed
pregnancy or history of frequent abortion.
 The American Dental Association (ADA) recommends
-that pregnant women eat a balanced diet, brush their teeth thoroughly with an
ADA-approved fluoride toothpaste twice a day, and floss daily
-Have preventive exams and cleanings during your pregnancy
-Let your dentist know you are pregnant
-Postpone non-emergency dental work until the second trimester or until after
delivery, if possible
-Elective procedures should be postponed until after the delivery
-Maintain healthy circulation by keeping your legs uncrossed while you sit in the
dentist's chair
-Take a pillow to help keep you and the baby more comfortable
-Bring headphones and some favorite music

30. THANK YOU