Inheritance due to genes located in cytoplasm is called cytoplasmic inheritance.
Since genes governing traits showing cytoplasmic inheritance are located outside the nucleus and in the cytoplasm, they are referred to as plasmagenes.
Maternal effects are the influences of a mothers genotype on the phenotype of her offspring. It results from the asymmetric contribution of the female parent to the development of zygotes.
In terms of chromosomal genes, both male and female parents contribute equally to the zygote. The female parent contributes to the zygotes initial cytoplasm and organelles. Sperm rarely contribute anything other than chromosomes. Therefore zygotic development begins within a maternal medium and hence the maternal cytoplasm directly affects zygotic development.
A complementation test (sometimes called a "cis-trans" test) can be used to test whether the mutations in two strains are in different genes. By taking an example of Benzer's work, complementation has been explained.
Maternal effects are the influences of a mothers genotype on the phenotype of her offspring. It results from the asymmetric contribution of the female parent to the development of zygotes.
In terms of chromosomal genes, both male and female parents contribute equally to the zygote. The female parent contributes to the zygotes initial cytoplasm and organelles. Sperm rarely contribute anything other than chromosomes. Therefore zygotic development begins within a maternal medium and hence the maternal cytoplasm directly affects zygotic development.
A complementation test (sometimes called a "cis-trans" test) can be used to test whether the mutations in two strains are in different genes. By taking an example of Benzer's work, complementation has been explained.
GENETICS
CYTOGENETICS
Definition of Linkage, Coupling and Repulsion hypothesis, Linkage group- Drosophila, maize and man, Types of linkage-complete linkage and incomplete linkage, Factors affecting linkage- distance between genes, age, temperature, radiation, sex, chemicals and nutrition, Significance of linkage.
The tendency of two or more genes to stay together (i.e., the co-existence of two or more genes) in the same chromosome during inheritance is known as LINKAGE. The linked genes are present on the same chromosome are said to be SYNTENIC. The linked genes do not show independent assortment.
LINKAGE v/s INDEPENDENT ASSORTMENT
The frequency of linkage or the strength recombination is influenced by several factors (agents).
Inability of a plant with functional pollen to set seed when self-pollinated.
Hindrance to self-fertilization.
Prevents inbreeding and promotes outcrossing.
Reported in about 70 families of angiosperms including crop species.
This PPT consists of 15 slides only explaining Pleiotropy. This is a phenomenon when one gene controls more than one trait , the traits may be related .Generally one gene's product acts for many reactions and so can affect more than one trait. Examples can be seen in pea Coloured flower and pigmentation in leaf axil, frizzle trait in chicken, fur colour and deafness in cats,Human pleiotropic traits are PKU,Sickle cell Anaemia. HOsyndrome , p53 gene etc
Introduction :
Mendel and subsequent workers assumed that a character was governed by a single gene.
But it was later discovered that many characters in almost all the organisms are governed by two or more genes. Such gene affect the development of concerned characters in various ways.
The phenomenon of two or more gene affecting the expression of each other in various ways in the development of a single character of on organism is known as gene interaction.
Chromosomes are known as hereditary vehicles
They are formed of strands of DNA molecules which contain information for the development of different characteristics and performance of various metabolic activities of the cells
The coordination of various function is brought about through the formation of enzymes which are complex protein molecules
GENETICS
CYTOGENETICS
Definition of Linkage, Coupling and Repulsion hypothesis, Linkage group- Drosophila, maize and man, Types of linkage-complete linkage and incomplete linkage, Factors affecting linkage- distance between genes, age, temperature, radiation, sex, chemicals and nutrition, Significance of linkage.
The tendency of two or more genes to stay together (i.e., the co-existence of two or more genes) in the same chromosome during inheritance is known as LINKAGE. The linked genes are present on the same chromosome are said to be SYNTENIC. The linked genes do not show independent assortment.
LINKAGE v/s INDEPENDENT ASSORTMENT
The frequency of linkage or the strength recombination is influenced by several factors (agents).
Inability of a plant with functional pollen to set seed when self-pollinated.
Hindrance to self-fertilization.
Prevents inbreeding and promotes outcrossing.
Reported in about 70 families of angiosperms including crop species.
This PPT consists of 15 slides only explaining Pleiotropy. This is a phenomenon when one gene controls more than one trait , the traits may be related .Generally one gene's product acts for many reactions and so can affect more than one trait. Examples can be seen in pea Coloured flower and pigmentation in leaf axil, frizzle trait in chicken, fur colour and deafness in cats,Human pleiotropic traits are PKU,Sickle cell Anaemia. HOsyndrome , p53 gene etc
Introduction :
Mendel and subsequent workers assumed that a character was governed by a single gene.
But it was later discovered that many characters in almost all the organisms are governed by two or more genes. Such gene affect the development of concerned characters in various ways.
The phenomenon of two or more gene affecting the expression of each other in various ways in the development of a single character of on organism is known as gene interaction.
Chromosomes are known as hereditary vehicles
They are formed of strands of DNA molecules which contain information for the development of different characteristics and performance of various metabolic activities of the cells
The coordination of various function is brought about through the formation of enzymes which are complex protein molecules
It is a powerpoint presentation that discusses about the lesson or topic: Non-Mendelian Inheritance. It also talks about the definition, history and the laws included in the Non-Mendelian Inheritance or Non-Mendelian Genetics.
EXTRA CHROMOSOMAL INHERITANCE & GENOME IMPRINTINGBiswarup Nandi
Cytoplasmic Inheritance:
Imagine genetic information passing from a mother to her child. It happens through tiny structures called organelles in the cell.
These organelles have their own set of instructions, separate from the cell’s nucleus.
Why is this important? Because it affects how traits are inherited!
Genomic Imprinting:
Think of it like a “parental tag” on genes. Some genes behave differently depending on whether they come from the mother or the father.
Epigenetics plays a role here—it’s like a switch that can turn genes on or off.
This process affects development and can lead to certain diseases.
Remember, these concepts help scientists understand how our genes work and why we’re unique! 🧬
Introduction
Maternal Inheritance
Organellar inheritance
Mitochondrial inheritance
Chloroplast inheritance
Inheritance involving kappa particle
INTRODUCTION
DNA or RNA is the Genetic materials carrying information from
one generation to another.
Besides these two nucleic acids the cytoplasm also
contributes to the inheritance of some characters in some
organisms.
Extra chromosomal inheritance is also defined as nonmendelian inheritance
Inheritance due to genes located in cytoplasm plasmagenes.
The genes are located in DNA present in mitochondria and in chloroplasts these
are called organellar genes. This type of inheritance is also called as
cytoplasmic inheritance.
The evidence of cytoplasmic inheritance was first presented by Carl Correns in
mirabilis jalapa.
In 1943, Sonnenborn discovered Kappa Particles in Paramecium and they are
inherited through cytoplasm.
In cytoplasmic inheritance the character of female parent is only transmitted to
the progeny
MATERNAL INHERITANCE
The character of only one of the two parents (usually female parent) is
transmitted to their progeny.
It is usually referred to as extra-chromosomal or maternal or uniparental
inheritance.
The transmission of cytoplasm differs between sex cells:
Sperm or pollen transfer little or no cytoplasm to the zygote, but Egg
Contributes almost all of the cytoplasm to the zygote
This pattern of mtDNA inheritance is well known as "maternal
inheritance.
ORGANELLAR INHERITANCE
The cytoplasmic organelles like plastids (chloroplast) and
mitochondria are involved.
The cytoplasmic inheritance is governed by the genes of
mitochondria and chloroplast.
The genes which involve in cytoplasmic inheritance are called
plasma genes or cytoplasmic genes or extra nuclear genes.
EXMAPLES FOR NON-MENDELIAN INHERITANCE
Plastid inheritance in Mirabilis
Kappa particles in Paramecium
Shell coiling in Snail
Cytoplasmic male sterility in Maize
Milk factor in mice
CHLOROPLAST INHERITANCE
LEAF VARIEGATION IN MIRABILIS JALAPA
The evidence for cytoplasmic inheritance was first presented by Carl
Correns in Mirabilis jalapa (Four ‘O’ clock plant).
He observed a strange pattern of inheritance and studied inheritance
of leaf variegation
In M. jalapa, leaves may be g
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
GENETICS AND VARIATION -1
Genetics is a branch of science which deals with the study of inheritance and variation.
Definition of terms
Heredity
Is a passing of features from parents to their young.
Variation
Possessing of characteristics which are different from these of the parents and other offsprings.
Genotype
Is the genetic constitution or make up of an organism
Phenotype
Is the outward or physical appearance of an organism
Dominant gene
Is a gene that prevents the expression of another gene.
Recessive gene
Is a gene that is masked by another gene.
Homozygous
Is a condition where by the two genes for a given trait are similar/ alike
Heterogeneous
Is a condition where the two genes for a trait are different.
Gene
Is a part of chromosome that carries the genetic material called DNA. Are also referred to as nucleotide chemical units of inheritance arranged along the chromosomes. They are called hereditary factors.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
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Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
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We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
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The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
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2. Inheritance due to genes located in cytoplasm
(plasmagenes) is called cytoplasmic inheritance.
Since genes governing traits showing cytoplasmic
inheritance are located outside the nucleus and in the
cytoplasm, they are referred to as plasmagenes.
The plasmagenes are located in DNA present in
mitochondria (mt DNA) and in chloroplasts (cp DNA).
Together both the DNAs are called organelle DNA.
Therefore, this type of inheritance is often referred to as
organellar inheritance, plastid inheritance or
mitochondrial inheritance.
3. In this, generally, the character of only one of the two
parents (usually female) is transmitted to the progeny.
Hence such inheritance is usually referred to as extra -
nuclear or extra-chromosomal or maternal or uniparental
inheritance.
The cytoplasmic inheritance is of two types: 1) Plastid
inheritance and 2) mitochondrial inheritance.
4. 1. Plastidial or chloroplast inheritance
Plastids are self duplicated and have some
amount of DNA and plays an important role in
cytoplasmic inheritance.
Plastids have green pigments called chloroplasts.
Chloroplasts contain a unique circular DNA (cp
DNA) in the stroma that is completely different
from the nuclear genome.
5. Leaf variegation in Mirabilis Jalapa
The conclusive evidence for cytoplasmic inheritance was first
presented by C. Correns in Mirabilis jalapa (Four ‘O’ clock
plant) in 1909.
He studied inheritance of leaf variegation in M. jalapa.
Variegation refers to the presence of white or yellow spots of
variable size on the green background of leaves.
In M. jalapa, leaves may be green, white or variegated. Some
branches may have only green, only white or only variegated
leaves.
Correns made crosses in all possible combinations among the
flowers produced on these three types of branches.
6. When flowers from green branch were used as
female parent, all the progeny were green
irrespective of the phenotype (green, white or
variegated) of male parent.
Similarly, progeny from crosses involving flowers
bloomed on white branches as female parent
were all white irrespective of the phenotype of
male parent.
But in progeny from all crosses involving flowers
born on variegated branches as female
parent, all the three types i.e. green, white and
variegated individuals were recovered in
variable proportions.
7.
8. The green leaf branches have normal chloroplasts,
white branches have mutant chloroplasts and
variegated have a mixture of both normal and
mutant chloroplasts.
The above results indicated that the inheritance is
governed by chloroplasts.
Since the cytoplasm is contributed to the zygote
mainly by female parent, the plastids are
transmitted to the zygote from the female parent.
Thus the plastids are responsible for variation in the
crosses of green, white and variegated leaves.
9. Inheritance of faulty mitochondrial genes
(maternal inheritance)
The number of mitochondria in every cell of a
person’s body varies from a few, to hundreds.
All of these mitochondria, and therefore the DNA
within the mitochondria, descend from the small
number of mitochondria present in the original
egg cell at the time of that person’s conception.
The sperm contributes very few mitochondria to
the baby.
10. An individual’s mitochondria are generally only
inherited from his or her mother. A change
(mutation) in one of the mitochondrial genes that
makes it faulty, can therefore be passed by the
mother to a child in her egg cells.
This pattern of inheritance is therefore often referred
to as maternal inheritance.
11. The egg cell contains many mitochondria, each
having on average one to several copies of the
mitochondrial genes.
If a particular gene in every mitochondrion in an
egg cell is faulty, the disruption to energy
production would be so severe that the early
embryo would probably not survive.
The fact that a person survives to birth and is
affected with a mitochondrial condition means
that they must have inherited two types of
mitochondria from his or her mother: some
containing the working copy of the gene, and
some containing the faulty gene.
12. The working copy of the mitochondrial gene will
still be able to send the right instructions, but the
amount of energy produced may be impacted
and may result in a mitochondrial condition.
On the other hand, having some mitochondria
with a faulty gene may cause no problem at all.