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Crossing Over
Presented by:
Sanjay Kr. Vishwakarma
Crossing Over
• Discovered by T. H. Morgan
• Recombination of genes on the same chromosome
• Parts of homologous chromosomes interchanged
Crossing Over
Crossing Over
Crossing Over
• Occurs during Meiosis-I
• Crossing over occur in mitotic division cause Loss of heterozygosity
• Loss of heterozygosity (LOH) is a gross chromosome even that
results in loss of the entire gene and the surrounding chromosomal
region
Crossing Over
• Crossing over is essential for normal segregation of chromosomes
during meiosis.
• Crossing over also accounts for genetic variation because due to the
swapping (to exchange something for another) of genetic materials
during crossing over.
Percentage of Crossing Over
• The percentage of crossing over is directly proportional to the distance between two genes
• Unit of distance between genes is centimorgan (cM)
Multiple Choice Question
1) Percentage of crossing over is more when
a) Genes are located in a different cell
b) Genes are not linked
c) Linked genes are located close to each other
d) Linked genes are located far apart from each other
Answer: d
2) If the percentage of crossing over between two genes is 10, then the distance between two
genes will be
a) 5 centimorgans
b) 10 centimorgans
c) 20 centimorgans
d) 40 map units
Answer: b
3) Alleles of different genes that are on the same chromosome may occasionally be separated
by a phenomenon known as
a) Pleiotropy
b) Epistasis
c) Continuous variation
d) Crossing over
Answer: d
4) Crossing over in diploid organism is responsible for
a) Dominance of gene
b) Linkage between genes
c) Recombination of linked allele
d) Segregation of alleles
Answer: c
Thank You

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Crossing over

  • 2. Crossing Over • Discovered by T. H. Morgan • Recombination of genes on the same chromosome • Parts of homologous chromosomes interchanged
  • 5. Crossing Over • Occurs during Meiosis-I • Crossing over occur in mitotic division cause Loss of heterozygosity • Loss of heterozygosity (LOH) is a gross chromosome even that results in loss of the entire gene and the surrounding chromosomal region
  • 6. Crossing Over • Crossing over is essential for normal segregation of chromosomes during meiosis. • Crossing over also accounts for genetic variation because due to the swapping (to exchange something for another) of genetic materials during crossing over.
  • 7. Percentage of Crossing Over • The percentage of crossing over is directly proportional to the distance between two genes • Unit of distance between genes is centimorgan (cM)
  • 9. 1) Percentage of crossing over is more when a) Genes are located in a different cell b) Genes are not linked c) Linked genes are located close to each other d) Linked genes are located far apart from each other Answer: d
  • 10. 2) If the percentage of crossing over between two genes is 10, then the distance between two genes will be a) 5 centimorgans b) 10 centimorgans c) 20 centimorgans d) 40 map units Answer: b
  • 11. 3) Alleles of different genes that are on the same chromosome may occasionally be separated by a phenomenon known as a) Pleiotropy b) Epistasis c) Continuous variation d) Crossing over Answer: d
  • 12. 4) Crossing over in diploid organism is responsible for a) Dominance of gene b) Linkage between genes c) Recombination of linked allele d) Segregation of alleles Answer: c