NES Pharmacy, Critical Appraisal 2011

Critical Appraisal Level 2 Evaluating studies using the Critical Appraisal Skills Programme (CASP) Tools

What is Critical Appraisal? ,[object Object],[object Object]

Why Critically Appraise? ,[object Object],[object Object]

Advantages of Critical Appraisal ,[object Object],[object Object],[object Object],[object Object]

Disadvantages of Critical Appraisal ,[object Object],[object Object],[object Object]

Help with Critical Appraisal ,[object Object],[object Object],[object Object]

CASP Tools ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

CASP Tools (2) ,[object Object],[object Object],[object Object],[object Object]

Randomised Controlled Trials (RCTSs) ,[object Object],[object Object]

RCTs (continued) ,[object Object],[object Object],[object Object]

Appraising RCTs ,[object Object],[object Object],[object Object],[object Object],[object Object]

Screening Questions in CASP tool ,[object Object],[object Object],[object Object],[object Object]

Validity ,[object Object],[object Object],[object Object]

Randomisation and Baseline Characteristics (Q3 in CASP Tool) ,[object Object],[object Object],[object Object],[object Object]

Randomisation and Baseline Characteristics (Q3 in CASP Tool) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Blinding (Q4 in CASP Tool) ,[object Object],[object Object],[object Object],[object Object],[object Object]

Follow-up (Q5 in CASP tool) ,[object Object],[object Object],[object Object]

Interventions (Q6 in CASP tool) ,[object Object],[object Object],[object Object],[object Object]

Sample Size (Q7 in CASP tool) ,[object Object],[object Object]

Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Presentation of Results (Q8 in CASP tool) ,[object Object],[object Object],[object Object],[object Object]

Presentation of Results (2) ,[object Object],[object Object],[object Object],[object Object]

Precision of Results (Q9 in CASP tool) ,[object Object],[object Object],[object Object]

Confidence Intervals (CI) ,[object Object],[object Object],[object Object],[object Object]

P-values ,[object Object],[object Object]

Statistics Used ,[object Object],[object Object],[object Object]

Clinical vs. Statistical Significance ,[object Object],[object Object],[object Object]

Relevance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Relevance to Local Population ,[object Object],[object Object],[object Object],[object Object]

Importance of outcomes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Risks versus Benefits ,[object Object],[object Object],[object Object],[object Object]

Other Considerations ,[object Object],[object Object],[object Object],[object Object]

Look out for…….. ,[object Object],[object Object],[object Object],[object Object],[object Object]

Sub-group analysis ,[object Object],[object Object],[object Object]

Use of Composite Endpoints ,[object Object],[object Object],[object Object],[object Object]

Analysis of Secondary Outcomes ,[object Object],[object Object],[object Object],[object Object]

Appraising other publications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Systematic Reviews ,[object Object],[object Object],[object Object],[object Object]

Systematic Reviews (2) ,[object Object],[object Object],[object Object]

Observational Studies ,[object Object],[object Object],[object Object]

Over to you…… ,[object Object]

NES Pharmacy, Critical Appraisal 2011

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