The classical equations of relative motion are translated by the theory of Special Relativity into relativistic equations. The origin of the Lorentz factor recapitulated.
Cosmic Adventure 5.3 Frames in Motion in RelativityStephen Kwong
The Einstein way of transforming time and location by the Lorentz factor, marking the departure from Newtonian physics. But why is it so is not explained.
Cosmic Adventure 5.2 Visonic Transform Without MotionStephen Kwong
The case when v=0 not covered by Relativity. Delay timing happens normally in static cases. The static case leads to the universe in spatial and temporal layers.It is just the world we live in.
Relativity, Visonics, Classical physics on acceleration. Different results in different views. Relativity results in lengthy and complicated equations, almost unworkable. But in visonics, apparent acceleration = actual acceleration.
The concept of length contraction in traditional theory of Special Relativity. Although seemingly verified by many experiment, its reality still remains controversial and pending amendment.
Cosmic Adventure 5.3 Frames in Motion in RelativityStephen Kwong
The Einstein way of transforming time and location by the Lorentz factor, marking the departure from Newtonian physics. But why is it so is not explained.
Cosmic Adventure 5.2 Visonic Transform Without MotionStephen Kwong
The case when v=0 not covered by Relativity. Delay timing happens normally in static cases. The static case leads to the universe in spatial and temporal layers.It is just the world we live in.
Relativity, Visonics, Classical physics on acceleration. Different results in different views. Relativity results in lengthy and complicated equations, almost unworkable. But in visonics, apparent acceleration = actual acceleration.
The concept of length contraction in traditional theory of Special Relativity. Although seemingly verified by many experiment, its reality still remains controversial and pending amendment.
CA 5.11 Velocity Transform in Relativity & VisonicsStephen Kwong
The kinematic entity of velocity is transformed in the Theory of Relativity by the Lorentz transformation of frames; in visionics, by delayed images. Simpler results in visonics.
Cosmic Adventure Episode 2.07 Secrets of MMXStephen Kwong
Angela explained where did MMX go wrong by comparing it with the correct one. MMX is doomed from the beginning. Yet it was kept until today because some idea spawn from it still prevails.
A young astronomer’s by now ten years old
results are re-told and put in perspective. The implications are
far-reaching. Angular-momentum shows its clout not only in
quantum mechanics where this is well known, but is also a
major player in the space-time theory of the equivalence
principle and its ramifications. In general relativity, its
fundamental role was largely neglected for the better part of a
century. A children’s device – a friction-free rotating bicycle
wheel suspended from its hub that can be lowered and pulled
up reversibly – serves as an eye-opener. The consequences are
embarrassingly far-reaching in reviving Einstein’s original
dream
Cosmic Adventure Episode 2.05 Michelson's River AnalogyStephen Kwong
Albert Michelson accepted the challenge and started the experiment which changed the course of modern physics. He compared the aether motion to the flow of a river as the basic idea of his experiment.
CA 5.11 Velocity Transform in Relativity & VisonicsStephen Kwong
The kinematic entity of velocity is transformed in the Theory of Relativity by the Lorentz transformation of frames; in visionics, by delayed images. Simpler results in visonics.
Cosmic Adventure Episode 2.07 Secrets of MMXStephen Kwong
Angela explained where did MMX go wrong by comparing it with the correct one. MMX is doomed from the beginning. Yet it was kept until today because some idea spawn from it still prevails.
A young astronomer’s by now ten years old
results are re-told and put in perspective. The implications are
far-reaching. Angular-momentum shows its clout not only in
quantum mechanics where this is well known, but is also a
major player in the space-time theory of the equivalence
principle and its ramifications. In general relativity, its
fundamental role was largely neglected for the better part of a
century. A children’s device – a friction-free rotating bicycle
wheel suspended from its hub that can be lowered and pulled
up reversibly – serves as an eye-opener. The consequences are
embarrassingly far-reaching in reviving Einstein’s original
dream
Cosmic Adventure Episode 2.05 Michelson's River AnalogyStephen Kwong
Albert Michelson accepted the challenge and started the experiment which changed the course of modern physics. He compared the aether motion to the flow of a river as the basic idea of his experiment.
BPO jobs in pune | Top BPO recruiters | Gratitude India manpower consultancy ...Gratitude India
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Lime is categorized as one of the most important building material which was mainly used in the ancient Greece, Rome and India.
There are many buildings which used lime for plastering and as a mortar.
This paper contains a Brief description on lime - as a building material.
Delay Sensitive Packet Scheduling Algorithm for MANETs by Cross LayerAM Publications
The delay sensitive packet scheduling and routing algorithm to effectively deliver delay sensitive data’s over a multihop
networks. First packet urgency, node urgency, route urgency are calculated on the basis of end-to-end delay requirements.
Based on these urgency metrics, the proposed packet scheduling algorithm determines the transmission order of each packet to
minimize the node urgency without unnecessary packet drop, and the proposed routing algorithm establishes a route to minimize
the derivatives of route urgency in order to maximize the number of packets delivered within the required end-to-end delay.
Finally experimental results are presented to evaluate the performance of the proposed joint working algorithms.
The second principle of Special Relativity Theory brought up a light which is unusual and unfamiliar. It is actually derived by the Michelson-Morley experiment as verified by the light path diagrams.
Lorentz and Fitzgerald picked up the MMX equation and developed the length contraction hypothesis to explain the failure of MMX. Lorentz transformation quation surface first time in history.
Solving the problem of similarity between exponents and trigonometric functions by introducing the imaginary number i resulted in the most beautiful equation - Euler's identity.
The basis for kinetics is Newton's second law, which states that when an unbalanced force acts on a particle, the particle will accelerate in the direction of the force with a magnitude that is proportional to the force.
ADAPTIVE CONTROL AND SYNCHRONIZATION OF A HIGHLY CHAOTIC ATTRACTORijistjournal
Recently, a novel three-dimensional highly chaotic attractor has been discovered by Srisuchinwong and Munmuangsaen (2010). This paper investigates the adaptive control and synchronization of this highly chaotic attractor with unknown parameters. First, adaptive control laws are designed to stabilize the highly chaotic system to its unstable equilibrium point at the origin based on the adaptive control theory and Lyapunov stability theory. Then adaptive control laws are derived to achieve global chaos synchronization of identical highly chaotic systems with unknown parameters. Numerical simulations are shown to demonstrate the effectiveness of the proposed adaptive control and synchronization schemes.
ADAPTIVE CONTROL AND SYNCHRONIZATION OF A HIGHLY CHAOTIC ATTRACTORijistjournal
Recently, a novel three-dimensional highly chaotic attractor has been discovered by Srisuchinwong and Munmuangsaen (2010). This paper investigates the adaptive control and synchronization of this highly chaotic attractor with unknown parameters. First, adaptive control laws are designed to stabilize the highly chaotic system to its unstable equilibrium point at the origin based on the adaptive control theory and Lyapunov stability theory. Then adaptive control laws are derived to achieve global chaos synchronization of identical highly chaotic systems with unknown parameters. Numerical simulations are shown to demonstrate the effectiveness of the proposed adaptive control and synchronization schemes.
The myphotonics project deals with the construction of opto-mechanical components and optical experiment implementation using modular systems such as LEGO®.
The components are low cost and the instructions that originated them are free to use. OpenAdaptonik and myphotonics can work together sharing the same purpose.
A series of satellite projects to secure more and better images of the Cosmic Microwave Background (CMB) since 1980. Age of universe estimated to be 13.73 billion years.
CA 10.01 Discovery of CMB (Cosmic Microwave Background)Stephen Kwong
Discovery of Cosmic Microwave Background by Arno Penzias and Robert Wilson in the 1960s. Found to be the relic radiation from the beginning of the Universe. One of the greatest discovery in science history so far.
Cosmic Adventure 5.8 Time Dilation of Clocks in Motion in VisonicsStephen Kwong
Time dilation phenomenon for clocks on the move in visonics. The result is the same as clocks at rest since the speed of light is not affected by the motion of the source.
Cosmic adventure 5.4 Moving Objects in VisonicsStephen Kwong
The visonic version of objects in motion. The approach is different from relativity and the results are also different. But they are all realistic and classical.
Cosmic adventure 4.6 Superlight in ActionStephen Kwong
Einstein introduced his equations for starlight aberration. But the audience found difficult to understanding, demanding explanation from the fundamentals. So Galileo was invited to present the classical basic.
Cosmic Adventure 4:1-4 Earth vs ZyrkoniaStephen Kwong
The tournament between Earth and Zyrkonia finally started. The first subject of contention is the difference between conventional light and superlight.
Visonics is the optical study of light with finite speed. The Earth version similar to it is called Relativity. The two need to be compared and so started a tournament between Earth and Zyrkonia.
The history of light speed measurement from Galileo to Romer. The result confirmed the finite speed of light and the wrong concept of Aristotle, leading to a new world of vision
Cosmic Adventure 3.04-6 World of Infinite Light SpeedStephen Kwong
The speed of light is essential to the theory of Relativity. So it is a must to know about the history of the infinite speed concept of light and the world so created as a basis of further discussions.
Cosmic Adventure 3.01 Making of the Pandora's BoxStephen Kwong
Einstein grasped the Excalibur and mixed it with time, space, and coordinate transformation, resulting in the theory of special relativity. The mix involved all the basics of physics resulting in the Pandora's box of modern physics. It became hard to extricate except with Zyrkonian solutions.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.