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CONSTIPATION
BHARAT,
POKHREL ,MD
Constipation
Defined as delay or difficulty in defecation
present for 2 weeks or longer and significant
to cause distress to the patient.
Other Terms To Know
Intractable constipation: Constipation not
responding to optimal conventional treatment
for at least 3 months.
Fecal Impaction: A hard mass in the lower
abdomen identified on PE or a dilated rectum
filled with large amount of stool on rectal
examination or excessive stool in the distal
colon on abdominal radiography.
FECAL IMPACTION
RESULTS IF CONSTIPATION IS NOT RELIEVED.
SYMPTOMS
LIQUID SEEPING
FROM ANUS
ABDOMINAL PAIN
NAUSEA, LOSS OF
APPETITE
ABDOMINAL
DISTENSION
RECTAL PAIN
TREATMENT
DIGITAL
REMOVAL
ENEMA
Other Terms to know
Soiling : the involuntary passage of fluid or
semi solid stool into clothing, usually as a
result of overflow from a faecally loaded
bowel.
Normal Bowel Movement
Varies from person to person
Some people have a bowel everyday, some every 2-3
days and some 2-3 times a
Some have bowel movement during the morning and
some in the evening.
Stools are normally brown in color
Feces are normally soft,formed,moist and shaped like
the rectum.
Constipation
Causes
A. Organic
 Structural: anal stenosis, anal fissure.
 Neuromuscular: Hirshprung disease, spina
bifida, pseudo obstruction.
 Metabolic: hypokalemia, hypercalcemia,
hypothyroidism, diabetes mellitus.
 Drugs: Narcotics, anticholenergic, lead,
 Intestinal: IBD, celiac disease,CF,tumors.
Constipation
Causes
B. Functional
In an otherwise healthy child constipation
may result simply from an episode of painful
defecation, difficulties during the period of
toilet training, inattention to the urge to
defecate because of involvement in other
activities or discomfort with toilet facilities.
Gastrointestinal disorders
Dietary: Lack of fiber and fluid intake
Motility:
Slow- transit constipation
Irritable Bowel Syndrome
Drugs
Chronic intestinal pseudo-obstruction
Causes
Structural
Colonic carcinoma
Diverticular disease
Hirschsprung’s disease
Defecation:
Anorectal disease (Crohn’s disease)
Obstructed defecation
Key components of
history-taking to
diagnose
constipation
Key
components
Potential
findings in a
child younger
than 1 year
Potential findings
in a child/young
person older than 1
year
Stool
patterns
•< 3 complete
stools per week
•Hard large stool
•'Rabbit
droppings)
•< 3 complete stools
per week
•Overflow soiling
•'Rabbit dropping
•Large, infrequent
stools that can block
the toilet
Key
components
Potential
findings in a
child younger
than 1 year
Potential findings in
a child/young
person older than 1
year
Symptoms
associated
with
defecation
•Distress on
stooling
•Bleeding
associated with
hard stool
•Straining
•Poor appetite that
improves with
passage of large stool
•Waxing & waning of
abdominal pain with
passage of stool
•Straining
•Anal pain
Key
compone
nts
Potential
findings in a
child younger
than 1 year
Potential findings in a
child/young person
older than 1 year
History •Previous
episode(s) of
constipation
•Previous or
current anal
fissure
•Previous episode(s) of
constipation
•Previous or current
anal fissure
•Painful bowel
movements and
bleeding associated
with hard stools
Constipation
Clinical features
A detailed history of pattern of defecation
may reveal stool-withholding behavior like
contracting the gluteal muscles by stiffening
the legs while lying down or holding on
furniture while standing, some children will
squat, push and cry which may be
misinterpreted as an attempt to defecate.
Accompanying symptoms include abdominal
pain, abdominal distention and flatulence.
Constipation
Clinical features
Sometimes rectal bleeding, poor appetite,
enuresis and history of UTI are associated.
 Soiling (an overflow incontinence of liquid
stool) can be
present in long
standing cases.
Constipation
Clinical features
 Physical examination of the abdomen may
reveal distention or palpable fecal masses.
Digital examination of the rectum is needed
to evaluate the sphincter and ampulla
Constipation
Diagnosis
 When no underlying cause is identified =>
history and physical examination
 laboratory tests => To rule out the organic
causes.
 Barium enema and anorectal manometry
are most helpful.
Diagnostic Criteria
The most widely accepted definitions for childhood
functional constipation => ROME III definitions,
which are divided into 2 main groups, based on the
age of the patients.
Infants up to 4 years have to fulfil >/2 criteria for at least
1 month
Children above 4 years have to fulfil >/2 of the criteria
for at least 2 months
Rome III diagnostic criteria
In the absence of organic pathology, >/2 of the
following must occur
For a child with developmental age <4 years
1. </ 2 defecations per week
2. At least 1 episode of incontinence per week after the
acquisition of toileting skills
3. History of excessive stool retention
4. History of painful or hard bowel movements
5. Presence of a large fecal mass in the rectum
6. History of large-diameter stools that may obstruct
the toilet
For a child >4 years with
insufficient criterias for IBS
<2 defecations in the toilet per week
At least 1 episode of fecal incontinence per week
History of retentive posturing or excessive volitional
stool retention
History of painful or hard bowel movements
Presence of a large fecal mass in the rectum
History of large-diameter stools that may obstruct the
toilet.
Constipation
Therapy
For functional constipation include:
1.Patient education, a regular bowel training
program including sitting on toilet for 5-10
minutes after each meal is often helpful in
establishing a regular bowel habits.
2. Relief of impaction can be achieved by
enema or polyethylene glycol.
Constipation
Therapy
 softening of stool by lactulose, high fiber diet,
or mineral oil must be continued until regular
bowel pattern has been established for
several months.
 Biofeedback training may be beneficial in
difficult cases.
Clinical guideline [CG99]
Published date: May 2010
Recommended laxative
doses
Macrogols
Laxatives Recommended doses
Polyethylene glycol 3350 +
electrolytes
Pediatric formula: Oral
powder: macrogol 3350
(polyethylene glycol 3350)a
6.563 g; sodium
bicarbonate 89.3 mg;
sodium chloride 175.4 mg;
potassium chloride 25.1
mg/sachet (unflavoured)
Osmotic laxatives
Laxatives Recommended doses
Lactulose •Child 1mon-1yr: 2.5 ml
twice daily, adjusted
according to response
•Child 1–5 years: 2.5–10
ml twice daily, adjusted
according to response
• 5–18 years: 5–20 ml
twice daily, adjusted
according to response
Stimulant laxatives
Laxatives Recommended doses
Sodium picosulfate Elixir (5 mg/5 ml)
•Child 1 month to 4 years:
2.5–10 mg once a day
•Child/young person 4–18
years: 2.5–20 mg once a
day
Perles (1 tablet = 2.5mg)
•Child/young person 4–18
years: 2.5–20mg once a
day
Stimulant laxatives
Laxatives Recommended doses
Bisacodyl •Child/young person 4–18
years: 5–20 mg once daily
(oral)
By rectum (suppository)
•Child/young person 2–18
years: 5–10 mg once daily
Stimulant laxatives
Laxatives Recommended doses
Docusate sodium •Child 6 months–2 years:
12.5 mg three times daily
(use paediatric oral
solution)
•Child 2–12 years: 12.5–
25 mg three times daily
(use paediatric oral
solution)
•Child/young person 12–
18 years: up to 500 mg
daily in divided doses
American dietary
recommendations
Total water intake per
day, including water
contained in food
Water obtained from
drinks per day
Infants 0–6 months 700 ml
assumed to be from
breast milk
7–12 months 800 ml
from milk and
complementary foods
and beverages
600 ml
1–3 years 1300 ml 900 ml
4–8 years 1700 ml 1200 ml
Boys 9–13 years 2400 ml 1800 ml
Girls 9–13 years 2100 ml 1600 ml
Boys 14–18 years 3300 ml 2600 ml
Girls 14–18 years 2300 ml 1800 ml
THANK YOU

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Constipation

  • 2. Constipation Defined as delay or difficulty in defecation present for 2 weeks or longer and significant to cause distress to the patient.
  • 3. Other Terms To Know Intractable constipation: Constipation not responding to optimal conventional treatment for at least 3 months. Fecal Impaction: A hard mass in the lower abdomen identified on PE or a dilated rectum filled with large amount of stool on rectal examination or excessive stool in the distal colon on abdominal radiography.
  • 4. FECAL IMPACTION RESULTS IF CONSTIPATION IS NOT RELIEVED. SYMPTOMS LIQUID SEEPING FROM ANUS ABDOMINAL PAIN NAUSEA, LOSS OF APPETITE ABDOMINAL DISTENSION RECTAL PAIN TREATMENT DIGITAL REMOVAL ENEMA
  • 5. Other Terms to know Soiling : the involuntary passage of fluid or semi solid stool into clothing, usually as a result of overflow from a faecally loaded bowel.
  • 6. Normal Bowel Movement Varies from person to person Some people have a bowel everyday, some every 2-3 days and some 2-3 times a Some have bowel movement during the morning and some in the evening. Stools are normally brown in color Feces are normally soft,formed,moist and shaped like the rectum.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13. Constipation Causes A. Organic  Structural: anal stenosis, anal fissure.  Neuromuscular: Hirshprung disease, spina bifida, pseudo obstruction.  Metabolic: hypokalemia, hypercalcemia, hypothyroidism, diabetes mellitus.  Drugs: Narcotics, anticholenergic, lead,  Intestinal: IBD, celiac disease,CF,tumors.
  • 14. Constipation Causes B. Functional In an otherwise healthy child constipation may result simply from an episode of painful defecation, difficulties during the period of toilet training, inattention to the urge to defecate because of involvement in other activities or discomfort with toilet facilities.
  • 15. Gastrointestinal disorders Dietary: Lack of fiber and fluid intake Motility: Slow- transit constipation Irritable Bowel Syndrome Drugs Chronic intestinal pseudo-obstruction
  • 16. Causes Structural Colonic carcinoma Diverticular disease Hirschsprung’s disease Defecation: Anorectal disease (Crohn’s disease) Obstructed defecation
  • 17. Key components of history-taking to diagnose constipation
  • 18. Key components Potential findings in a child younger than 1 year Potential findings in a child/young person older than 1 year Stool patterns •< 3 complete stools per week •Hard large stool •'Rabbit droppings) •< 3 complete stools per week •Overflow soiling •'Rabbit dropping •Large, infrequent stools that can block the toilet
  • 19. Key components Potential findings in a child younger than 1 year Potential findings in a child/young person older than 1 year Symptoms associated with defecation •Distress on stooling •Bleeding associated with hard stool •Straining •Poor appetite that improves with passage of large stool •Waxing & waning of abdominal pain with passage of stool •Straining •Anal pain
  • 20. Key compone nts Potential findings in a child younger than 1 year Potential findings in a child/young person older than 1 year History •Previous episode(s) of constipation •Previous or current anal fissure •Previous episode(s) of constipation •Previous or current anal fissure •Painful bowel movements and bleeding associated with hard stools
  • 21. Constipation Clinical features A detailed history of pattern of defecation may reveal stool-withholding behavior like contracting the gluteal muscles by stiffening the legs while lying down or holding on furniture while standing, some children will squat, push and cry which may be misinterpreted as an attempt to defecate. Accompanying symptoms include abdominal pain, abdominal distention and flatulence.
  • 22. Constipation Clinical features Sometimes rectal bleeding, poor appetite, enuresis and history of UTI are associated.  Soiling (an overflow incontinence of liquid stool) can be present in long standing cases.
  • 23. Constipation Clinical features  Physical examination of the abdomen may reveal distention or palpable fecal masses. Digital examination of the rectum is needed to evaluate the sphincter and ampulla
  • 24. Constipation Diagnosis  When no underlying cause is identified => history and physical examination  laboratory tests => To rule out the organic causes.  Barium enema and anorectal manometry are most helpful.
  • 25. Diagnostic Criteria The most widely accepted definitions for childhood functional constipation => ROME III definitions, which are divided into 2 main groups, based on the age of the patients. Infants up to 4 years have to fulfil >/2 criteria for at least 1 month Children above 4 years have to fulfil >/2 of the criteria for at least 2 months
  • 26. Rome III diagnostic criteria In the absence of organic pathology, >/2 of the following must occur For a child with developmental age <4 years
  • 27. 1. </ 2 defecations per week 2. At least 1 episode of incontinence per week after the acquisition of toileting skills 3. History of excessive stool retention 4. History of painful or hard bowel movements 5. Presence of a large fecal mass in the rectum 6. History of large-diameter stools that may obstruct the toilet
  • 28. For a child >4 years with insufficient criterias for IBS <2 defecations in the toilet per week At least 1 episode of fecal incontinence per week History of retentive posturing or excessive volitional stool retention History of painful or hard bowel movements Presence of a large fecal mass in the rectum History of large-diameter stools that may obstruct the toilet.
  • 29. Constipation Therapy For functional constipation include: 1.Patient education, a regular bowel training program including sitting on toilet for 5-10 minutes after each meal is often helpful in establishing a regular bowel habits. 2. Relief of impaction can be achieved by enema or polyethylene glycol.
  • 30. Constipation Therapy  softening of stool by lactulose, high fiber diet, or mineral oil must be continued until regular bowel pattern has been established for several months.  Biofeedback training may be beneficial in difficult cases.
  • 31. Clinical guideline [CG99] Published date: May 2010 Recommended laxative doses
  • 32. Macrogols Laxatives Recommended doses Polyethylene glycol 3350 + electrolytes Pediatric formula: Oral powder: macrogol 3350 (polyethylene glycol 3350)a 6.563 g; sodium bicarbonate 89.3 mg; sodium chloride 175.4 mg; potassium chloride 25.1 mg/sachet (unflavoured)
  • 33. Osmotic laxatives Laxatives Recommended doses Lactulose •Child 1mon-1yr: 2.5 ml twice daily, adjusted according to response •Child 1–5 years: 2.5–10 ml twice daily, adjusted according to response • 5–18 years: 5–20 ml twice daily, adjusted according to response
  • 34. Stimulant laxatives Laxatives Recommended doses Sodium picosulfate Elixir (5 mg/5 ml) •Child 1 month to 4 years: 2.5–10 mg once a day •Child/young person 4–18 years: 2.5–20 mg once a day Perles (1 tablet = 2.5mg) •Child/young person 4–18 years: 2.5–20mg once a day
  • 35. Stimulant laxatives Laxatives Recommended doses Bisacodyl •Child/young person 4–18 years: 5–20 mg once daily (oral) By rectum (suppository) •Child/young person 2–18 years: 5–10 mg once daily
  • 36. Stimulant laxatives Laxatives Recommended doses Docusate sodium •Child 6 months–2 years: 12.5 mg three times daily (use paediatric oral solution) •Child 2–12 years: 12.5– 25 mg three times daily (use paediatric oral solution) •Child/young person 12– 18 years: up to 500 mg daily in divided doses
  • 38. Total water intake per day, including water contained in food Water obtained from drinks per day Infants 0–6 months 700 ml assumed to be from breast milk 7–12 months 800 ml from milk and complementary foods and beverages 600 ml 1–3 years 1300 ml 900 ml 4–8 years 1700 ml 1200 ml Boys 9–13 years 2400 ml 1800 ml Girls 9–13 years 2100 ml 1600 ml Boys 14–18 years 3300 ml 2600 ml Girls 14–18 years 2300 ml 1800 ml

Editor's Notes

  1. Accompanying symptoms may include irritability, decreased appetite, and/or early satiety, which may disappear immediately following passage of a large stool