This document discusses the importance of providing minerals to animals in organic forms like chelates and proteinates. It notes that inorganic minerals are not well absorbed and can be toxic. Organic mineral forms bind with amino acids or proteins, forming complexes that are more bioavailable and do not compete with each other for absorption. The document recommends using proteinated minerals in animal feed to improve health, immunity, nutrient absorption and production while reducing environmental pollution from mineral excretion.
Role of Oxidative Stress in Assessment of Damage Induced by Lead Acetate in M...ijtsrd
Heavy metal deposition has increased due to the anthropogenic activities leading to heavily polluted areas worldwide. The objective of present study was to evaluate the effect of lead acetate Pb C2H3O2 2 on antioxidant enzyme activities in gastrocnemius muscle of mice. Lead is a toxic heavy metal widely distributed in the environment due to its role in modern industry. Normal healthy looking mice showing no sign of morbidity were divided into three groups. Group I was designated as control whereas group II and group III received lead acetate having doses 10 mg kg body weight of lead acetate, daily and 150 mg kg body weight of lead acetate, weekly respectively. Study was performed at 40 and 80 days stages. Lead acetate significantly decreases antioxidant enzymes and increase oxidative stress along with muscle tissue damage. Sushma Sharma | Anita Thakur "Role of Oxidative Stress in Assessment of Damage Induced by Lead Acetate in Mice Gastrocnemius Muscle" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-1 , December 2018, URL: http://www.ijtsrd.com/papers/ijtsrd18927.pdf
http://www.ijtsrd.com/biological-science/zoology/18927/role-of-oxidative-stress-in-assessment-of-damage-induced-by-lead-acetate-in-mice-gastrocnemius-muscle/sushma-sharma
Antioxidant potentials of tannic acid on lipid peroxidation induced by severa...Premier Publishers
Various prospective studies have indicated the antioxidant potency of tannic acid in several models. However, there is no clear-cut evidence revealing that the reported antioxidant properties of tannic acid remains potent regardless of the lipid sources and pro-oxidants employed for the oxidative assault. Hence, this study sought to investigate the antioxidant properties of tannic acid against cerebral and hepatic lipid peroxidation induced by several pro-oxidants (Iron (II) sulfate, Sodium nitroprusside, cyclophosphamide and acetaminophen) in vitro. Rats were decapitated under mild ether anesthesia and the tissues were rapidly dissected, placed on ice, weighed and immediately homogenized in cold 50 mM Tris-HCl, pH 7.4 (1/10, w/v). The homogenates were centrifuged for 10 min at 4000 g to yield a pellet that was discarded and a low-speed supernatant (S1). Our results indicated that Fe (II) showed the highest pro-oxidative effects in both tissues lipids. Furthermore, tannic acid demonstrated potent inhibitory effects against lipid peroxidation in both tissues lipids regardless of the pro-oxidant employed. To this end, there is a dire need to exploit the protective benefits of tannic acid as a potential exogenous antioxidant against lipid peroxidation with a view to providing solution to the global oxidative stress menace.
Nutrition and respiration are essential life processes. Nutrition involves taking in nutrients from food to provide energy and materials for growth through processes like ingestion, digestion, absorption, assimilation and egestion. There are two main types of nutrition - autotrophic where organisms produce their own food (like plants) and heterotrophic where food is obtained from other organisms. Respiration is the process by which living beings break down food to release energy. It involves breaking down glucose and pyruvate through aerobic and anaerobic pathways to produce energy molecules like ATP. Exchange of gases like oxygen and carbon dioxide is also crucial for aerobic respiration.
Glutathione is the body's most important antioxidant, protecting cells from free radicals. Chronic alcohol use and certain drugs like acetaminophen can deplete glutathione levels. RiboCeine was designed to provide the rate-limiting amino acid L-cysteine in a bioavailable form to support glutathione production. Studies showed RiboCeine was more effective than N-acetylcysteine at protecting mice from liver damage from toxic acetaminophen doses. Further research found RiboCeine restored glutathione levels and had protective effects in animal models of conditions linked to oxidative stress. RiboCeine dissociates into D-ribose and L-cysteine after ingestion to support glutathione biosynthesis.
This document discusses essential and trace metal ions in biological systems. It begins by stating that all living organisms require certain elements in large quantities for growth and development, as well as some in trace amounts. There are criteria for an element to be considered essential, including being necessary for normal growth/reproduction and being directly involved in metabolism. Essential metals include sodium, potassium, magnesium, calcium, molybdenum and zinc, while beneficial metals include lithium, vanadium and chromium. The document further discusses classification of essential elements, importance of trace elements, and provides examples of essential elements like iron, iodine, zinc, manganese, calcium, potassium, sodium and copper.
LYCOTENFORTE CapsulesTM: The most powerful antioxidant mentains optimum healt...SriramNagarajan16
Oxidation is a chemical reaction that transfers electrons from a substance to anoxidizing agent Oxidation
reactions can produce free radicals. In turn, these radicals can start chain reactions.
Antioxidants terminate the chain reactions by removing free radical intermediates, and inhibit other oxidation
reactions. They do this by being oxidized themselves, so antioxidants are often called as reducing agents such
as thiols, ascorbic acid or polyphenols.
Antioxidants are widely used as ingredients in dietary supplements and have been investigated for the
prevention of diseases such as cancer, coronary heart disease and even altitude sickness.
Antioxidants are our first line of defense against free radical damage, and are critical for maintaining optimum
health and wellbeing. The need for antioxidants becomes even more critical with increased exposure to free
radicals. Pollution, cigarette smoke, drugs, illness, stress, and even exercise can increase free radical exposure.
Because so many factors can contribute to oxidative stress, individual assessment of susceptibility becomes
important. Many experts believe that the Recommended Dietary Allowance (RDA) for specific antioxidants
may be inadequate and, in some instances, the need may be several times the RDA. As part of a healthy lifestyle
and a well-balanced, wholesome diet, antioxidant supplementation is now being recognized as an important
means of improving free radical protection. Damage to cells caused by free radicals is believed to play a central
role in the aging process and in disease progression. The present paper Reviews the Role of LYCOTENFORTE
Capsules in maintaining optimum health and wellbeing.
Role of Oxidative Stress in Assessment of Damage Induced by Lead Acetate in M...ijtsrd
Heavy metal deposition has increased due to the anthropogenic activities leading to heavily polluted areas worldwide. The objective of present study was to evaluate the effect of lead acetate Pb C2H3O2 2 on antioxidant enzyme activities in gastrocnemius muscle of mice. Lead is a toxic heavy metal widely distributed in the environment due to its role in modern industry. Normal healthy looking mice showing no sign of morbidity were divided into three groups. Group I was designated as control whereas group II and group III received lead acetate having doses 10 mg kg body weight of lead acetate, daily and 150 mg kg body weight of lead acetate, weekly respectively. Study was performed at 40 and 80 days stages. Lead acetate significantly decreases antioxidant enzymes and increase oxidative stress along with muscle tissue damage. Sushma Sharma | Anita Thakur "Role of Oxidative Stress in Assessment of Damage Induced by Lead Acetate in Mice Gastrocnemius Muscle" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-1 , December 2018, URL: http://www.ijtsrd.com/papers/ijtsrd18927.pdf
http://www.ijtsrd.com/biological-science/zoology/18927/role-of-oxidative-stress-in-assessment-of-damage-induced-by-lead-acetate-in-mice-gastrocnemius-muscle/sushma-sharma
Antioxidant potentials of tannic acid on lipid peroxidation induced by severa...Premier Publishers
Various prospective studies have indicated the antioxidant potency of tannic acid in several models. However, there is no clear-cut evidence revealing that the reported antioxidant properties of tannic acid remains potent regardless of the lipid sources and pro-oxidants employed for the oxidative assault. Hence, this study sought to investigate the antioxidant properties of tannic acid against cerebral and hepatic lipid peroxidation induced by several pro-oxidants (Iron (II) sulfate, Sodium nitroprusside, cyclophosphamide and acetaminophen) in vitro. Rats were decapitated under mild ether anesthesia and the tissues were rapidly dissected, placed on ice, weighed and immediately homogenized in cold 50 mM Tris-HCl, pH 7.4 (1/10, w/v). The homogenates were centrifuged for 10 min at 4000 g to yield a pellet that was discarded and a low-speed supernatant (S1). Our results indicated that Fe (II) showed the highest pro-oxidative effects in both tissues lipids. Furthermore, tannic acid demonstrated potent inhibitory effects against lipid peroxidation in both tissues lipids regardless of the pro-oxidant employed. To this end, there is a dire need to exploit the protective benefits of tannic acid as a potential exogenous antioxidant against lipid peroxidation with a view to providing solution to the global oxidative stress menace.
Nutrition and respiration are essential life processes. Nutrition involves taking in nutrients from food to provide energy and materials for growth through processes like ingestion, digestion, absorption, assimilation and egestion. There are two main types of nutrition - autotrophic where organisms produce their own food (like plants) and heterotrophic where food is obtained from other organisms. Respiration is the process by which living beings break down food to release energy. It involves breaking down glucose and pyruvate through aerobic and anaerobic pathways to produce energy molecules like ATP. Exchange of gases like oxygen and carbon dioxide is also crucial for aerobic respiration.
Glutathione is the body's most important antioxidant, protecting cells from free radicals. Chronic alcohol use and certain drugs like acetaminophen can deplete glutathione levels. RiboCeine was designed to provide the rate-limiting amino acid L-cysteine in a bioavailable form to support glutathione production. Studies showed RiboCeine was more effective than N-acetylcysteine at protecting mice from liver damage from toxic acetaminophen doses. Further research found RiboCeine restored glutathione levels and had protective effects in animal models of conditions linked to oxidative stress. RiboCeine dissociates into D-ribose and L-cysteine after ingestion to support glutathione biosynthesis.
This document discusses essential and trace metal ions in biological systems. It begins by stating that all living organisms require certain elements in large quantities for growth and development, as well as some in trace amounts. There are criteria for an element to be considered essential, including being necessary for normal growth/reproduction and being directly involved in metabolism. Essential metals include sodium, potassium, magnesium, calcium, molybdenum and zinc, while beneficial metals include lithium, vanadium and chromium. The document further discusses classification of essential elements, importance of trace elements, and provides examples of essential elements like iron, iodine, zinc, manganese, calcium, potassium, sodium and copper.
LYCOTENFORTE CapsulesTM: The most powerful antioxidant mentains optimum healt...SriramNagarajan16
Oxidation is a chemical reaction that transfers electrons from a substance to anoxidizing agent Oxidation
reactions can produce free radicals. In turn, these radicals can start chain reactions.
Antioxidants terminate the chain reactions by removing free radical intermediates, and inhibit other oxidation
reactions. They do this by being oxidized themselves, so antioxidants are often called as reducing agents such
as thiols, ascorbic acid or polyphenols.
Antioxidants are widely used as ingredients in dietary supplements and have been investigated for the
prevention of diseases such as cancer, coronary heart disease and even altitude sickness.
Antioxidants are our first line of defense against free radical damage, and are critical for maintaining optimum
health and wellbeing. The need for antioxidants becomes even more critical with increased exposure to free
radicals. Pollution, cigarette smoke, drugs, illness, stress, and even exercise can increase free radical exposure.
Because so many factors can contribute to oxidative stress, individual assessment of susceptibility becomes
important. Many experts believe that the Recommended Dietary Allowance (RDA) for specific antioxidants
may be inadequate and, in some instances, the need may be several times the RDA. As part of a healthy lifestyle
and a well-balanced, wholesome diet, antioxidant supplementation is now being recognized as an important
means of improving free radical protection. Damage to cells caused by free radicals is believed to play a central
role in the aging process and in disease progression. The present paper Reviews the Role of LYCOTENFORTE
Capsules in maintaining optimum health and wellbeing.
Nico wanandy unsw mechanism of antioxidant for the skinNico Wanandy
The document summarizes research on antioxidants and their role in protecting skin from oxidative stress. It discusses how UV radiation from the sun generates reactive oxygen species that can damage skin cells. Antioxidants from foods like vitamins C and E, carotenoids, and flavonoids can help combat this by neutralizing free radicals. The document also examines the endogenous antioxidant defense system in cells, including enzymes like superoxide dismutase, catalase, and glutathione peroxidase that protect mitochondria from oxidative damage. Preliminary experiments suggest natural extracts may help alleviate the damaging effects of hydrogen peroxide on cells.
This document discusses nutrition and inflammation. It outlines that acute inflammation is the body's normal response to injury or infection, while chronic inflammation can be caused by persistent triggers and can lead to diseases. Certain nutrients like high-GI carbohydrates, trans fats, and saturated fats are pro-inflammatory, while omega-3s and antioxidants are anti-inflammatory. While antioxidants can reduce oxidative stress, high doses may also be pro-oxidative, and antioxidant supplements have not been found effective for disease prevention in most cases. Chronic inflammation results from ongoing injuries, persistent triggers, autoimmunity, tissue damage and oxidative stress.
Sulfur is an essential element that plays an important role in biological processes through electron transfers. Understanding sulfur metabolism in model organisms like Escherichia coli and Bacillus subtilis is important to extend knowledge to other ecological niches. Sulfur metabolism involves three main processes: synthesis of sulfur-containing amino acids and coenzymes, catabolism and equilibration of sulfur molecules, and methionine recycling. Iron-sulfur proteins and copper proteins participate in one-electron transfers involving oxidation states of iron and copper.
This document discusses antioxidants and their role in protecting against free radical damage. It defines antioxidants as substances that inhibit oxidation reactions and describes how free radicals form and damage cells. The document then classifies antioxidants, describes how they work to neutralize free radicals, and lists important antioxidant vitamins and foods containing them. It discusses the role of antioxidants in protecting against various oral diseases and conditions like cancer and periodontal disease.
Free radicals are unstable molecules with unpaired electrons that can cause oxidative damage. They are produced during normal metabolism but also due to environmental toxins and radiation. Antioxidants help stabilize free radicals and prevent cellular damage. The body has endogenous antioxidants like glutathione, vitamin C and E, and antioxidant enzymes. Exogenous antioxidants from foods and supplements can further support the antioxidant defense system. Oxidative stress occurs when there is an imbalance between free radicals and antioxidants leading to diseases. Maintaining adequate antioxidant levels through diet and lifestyle can help reduce oxidative damage and disease risk.
LYCOZEN-GT A SUPER ANTI-OXIDANT MULTIVITAMINpharmaindexing
This document discusses the formulation LYCOZEN-GT, a super antioxidant multivitamin and multimineral supplement containing lycopene, green tea extract, and grape seed extract. It provides background on oxidative stress and antioxidants, describing how free radicals damage cells and the body's antioxidant defenses. The formulation aims to provide antioxidants that protect against this damage. The document details the ingredients in LYCOZEN-GT and their roles in combating oxidative stress and related diseases.
Polyether antibiotics include lasalocid, maduramicin, monensin, narasin, salinomycin, and semduramicin. They are used exclusively in veterinary medicine as antibacterials and to prevent coccidiosis. These ionophores bind and transport metal ions across cell membranes, disrupting ion gradients in bacteria and protozoa and ultimately exhausting their energy, leading to cell death. They were discovered through fermentation of various Streptomyces and Actinomadura bacteria between 1951-1988 and are most effective against gram-positive bacteria and coccidia.
Copper Nanoparticles and Antioxidant Stress: Problem Makers or Solvers?_ Cri...CrimsonpublishersNTNF
Copper nanoparticles (NPs) have various applications but also pose environmental concerns. They can act as both problem makers and problem solvers. As problem makers, copper NPs may accumulate in the environment and cause toxicity in plants and animals over the long term. However, they also show promise as problem solvers by demonstrating antibacterial properties useful for wound dressings, and potential antioxidant and antidiabetic effects. More research is still needed to fully understand the ecological effects of copper NP exposure and their long term impacts on human health before their widespread use can be considered safe.
Ionophores are lipid-soluble compounds that form complexes to transport ions across biological membranes. They play an important role in improving livestock and poultry health and feed efficiency. Ionophores are produced by microorganisms and act by increasing the permeability of cell membranes to specific cations. Common ionophores used in animal feed include monensin, lasalocid, and salinomycin.
This document summarizes the key points from a meeting discussing the role of reactive oxygen species (ROS) in physiological processes. The meeting highlighted that ROS produced during moderate exercise are beneficial, not detrimental, as they promote muscle adaptation, endurance performance, and antioxidant defenses. However, excessive ROS from exhaustive exercise can damage cells. The discussion reconsidered definitions of oxidative stress and antioxidants, noting that ROS also have important signaling functions and that mild oxidative stress can trigger protective responses. More research is still needed to fully understand ROS regulation and when levels become harmful versus beneficial.
Schiff bases are compounds containing an imine or azomethine (-C=N-) functional group formed through condensation reactions between primary amines and carbonyl compounds. They have a wide variety of applications including as catalysts, pigments, dyes, polymers stabilizers, and in organic synthesis. Schiff bases also exhibit biological activities such as antimicrobial, anticancer, anti-inflammatory, and more. Transition metal complexes of Schiff bases have particularly shown potential as antimicrobial drugs and DNA binding agents. Due to the lone pair of electrons on nitrogen, Schiff bases have basic properties and can form insoluble salts through reactions with strong acids.
PPT on Protective Activity Of Certain Important Antioxidant Naveen K L
This document categorizes and describes various antioxidants. It discusses how antioxidants are classified based on their mode of action, location, and solubility. The major groups of antioxidants found in plants are enzymes, minerals, low and high molecular weight compounds, vitamins, hormones, and essential oils. Antioxidants play an important biological role in boosting the immune system, preventing neurodegenerative disorders, and promoting cardiovascular health. They can also be used therapeutically for conditions like Alzheimer's, cataracts, diabetes, and skin aging.
This document discusses essential plant nutrients and how they are classified. It outlines that 17 elements are considered essential for plant growth according to specific criteria. These elements can be classified based on their concentration in plants as either macronutrients, which are needed in larger quantities, or micronutrients, which are needed in smaller amounts. They can also be classified into four groups based on their biochemical behavior and physiological functions in plants. The four groups include elements that are major constituents of organic materials, involved in biochemical reactions, present in free ionic states or adsorbed to organic anions, or predominantly present as chelates.
Antioxidants /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Defence mechanism of antioxidant in Human BodyImad Khan
This document summarizes the antioxidant defense mechanism in the human body. It discusses what free radicals are and their main sources, as well as the antioxidant defense system that protects the body from free radical damage. The defense system includes antioxidant compounds and enzymes that act at different levels - prevention, interception, and repair - to neutralize free radicals. Some key antioxidant compounds and their roles are also described.
Acute Toxicity and Bioaccumulation Patterns of Lead and Zinc in Juveniles of ...iosrjce
Acute toxicity of lead and zinc salts (Pb(NO3)2 and ZnCl2) and their bioaccumulation patterns in
juveniles of Clarias gariepinus was investigated. ZnCl2 with a 96hr LC50 value of 15.301mg/l was found to be
more toxic than Pb(NO3)2 with a 96hr LC50 value of 51.516mg/l. ZnCl2 was bio-accumulated at a faster rate
in the gills and flesh of the fish than Pb(NO3)2 . The amount of ZnCl2 and Pb(NO3)2 bio-accumulated reduced
as the experiment proceeded. Higher levels of ZnCl2 were recorded in the gills than in the flesh of the juvenile
fishes. Essential heavy metals can be more toxic to aquatic organisms than non essential heavy metals when the
former is present in high enough concentrations. Water chemistry, speciation and bio-availability of heavy
metals in surrounding media are major factors that determine rate of accumulation in aquatic organisms.
This document discusses reactive oxygen species (ROS), antioxidants, and their roles in various disorders. It begins by defining ROS as unstable molecules that can damage cells, and listing their sources. ROS are necessary in small amounts but can cause issues in excess. Antioxidants help neutralize ROS and prevent oxidative damage. The document then examines the roles of ROS and antioxidants in specific disorders like diabetes, cardiovascular disease, chronic fatigue, cancers, pregnancy complications, and male infertility. It provides treatment options like antioxidant supplementation to help control ROS levels and reduce related disease complications.
This document provides the front matter, including title page, dedication page, and contents page, for a book titled "Antioxidants in Human Health and Disease". The book is edited by Tapan K. Basu, Norman J. Temple, and Manohar L. Garg and contains 27 chapters contributed by various authors on topics related to antioxidants and their role in human health and disease. The book is published by CABI Publishing and copyrighted in 1999.
This document summarizes key concepts from chapters 6-8 of a microbiology textbook including:
- The essential nutrients required by microbes including carbon, hydrogen, oxygen, nitrogen, phosphorus, and sulfur.
- The chemical composition of E. coli and what microbes use as energy and carbon sources, categorizing them as autotrophs and heterotrophs.
- The processes of osmosis, diffusion, and endocytosis that transport substances into and out of cells.
- Temperature categories for microbes like psychrophiles, psychrotrophs and how gases like oxygen and carbon dioxide influence microbial growth.
Reactive oxygen species and anti-oxidantsPeriowiki.com
This document discusses reactive oxygen species (ROS) and antioxidants. It begins with a brief history of the discovery of oxygen, free radicals, and their role in biology. ROS are classified and sources both endogenous and exogenous are described. The document outlines the origins and formation of ROS, as well as their beneficial roles in physiological functions and microbial destruction. However, excessive ROS can also cause tissue damage through lipid peroxidation and DNA damage. The body's antioxidant defense systems and how ROS levels impact periodontal health are examined. The conclusion discusses measuring ROS and antioxidants.
The document discusses drug delivery and amino acid chelated minerals. It notes that amino acid chelates have higher bioavailability than inorganic minerals due to resisting precipitation in the intestinal tract. It then summarizes several SKP Pharma products that use amino acid chelated minerals, including Calcifer for anemia and bone health, Osteoforte for bone health, and GlucoTin DS for joint support.
Nico wanandy unsw mechanism of antioxidant for the skinNico Wanandy
The document summarizes research on antioxidants and their role in protecting skin from oxidative stress. It discusses how UV radiation from the sun generates reactive oxygen species that can damage skin cells. Antioxidants from foods like vitamins C and E, carotenoids, and flavonoids can help combat this by neutralizing free radicals. The document also examines the endogenous antioxidant defense system in cells, including enzymes like superoxide dismutase, catalase, and glutathione peroxidase that protect mitochondria from oxidative damage. Preliminary experiments suggest natural extracts may help alleviate the damaging effects of hydrogen peroxide on cells.
This document discusses nutrition and inflammation. It outlines that acute inflammation is the body's normal response to injury or infection, while chronic inflammation can be caused by persistent triggers and can lead to diseases. Certain nutrients like high-GI carbohydrates, trans fats, and saturated fats are pro-inflammatory, while omega-3s and antioxidants are anti-inflammatory. While antioxidants can reduce oxidative stress, high doses may also be pro-oxidative, and antioxidant supplements have not been found effective for disease prevention in most cases. Chronic inflammation results from ongoing injuries, persistent triggers, autoimmunity, tissue damage and oxidative stress.
Sulfur is an essential element that plays an important role in biological processes through electron transfers. Understanding sulfur metabolism in model organisms like Escherichia coli and Bacillus subtilis is important to extend knowledge to other ecological niches. Sulfur metabolism involves three main processes: synthesis of sulfur-containing amino acids and coenzymes, catabolism and equilibration of sulfur molecules, and methionine recycling. Iron-sulfur proteins and copper proteins participate in one-electron transfers involving oxidation states of iron and copper.
This document discusses antioxidants and their role in protecting against free radical damage. It defines antioxidants as substances that inhibit oxidation reactions and describes how free radicals form and damage cells. The document then classifies antioxidants, describes how they work to neutralize free radicals, and lists important antioxidant vitamins and foods containing them. It discusses the role of antioxidants in protecting against various oral diseases and conditions like cancer and periodontal disease.
Free radicals are unstable molecules with unpaired electrons that can cause oxidative damage. They are produced during normal metabolism but also due to environmental toxins and radiation. Antioxidants help stabilize free radicals and prevent cellular damage. The body has endogenous antioxidants like glutathione, vitamin C and E, and antioxidant enzymes. Exogenous antioxidants from foods and supplements can further support the antioxidant defense system. Oxidative stress occurs when there is an imbalance between free radicals and antioxidants leading to diseases. Maintaining adequate antioxidant levels through diet and lifestyle can help reduce oxidative damage and disease risk.
LYCOZEN-GT A SUPER ANTI-OXIDANT MULTIVITAMINpharmaindexing
This document discusses the formulation LYCOZEN-GT, a super antioxidant multivitamin and multimineral supplement containing lycopene, green tea extract, and grape seed extract. It provides background on oxidative stress and antioxidants, describing how free radicals damage cells and the body's antioxidant defenses. The formulation aims to provide antioxidants that protect against this damage. The document details the ingredients in LYCOZEN-GT and their roles in combating oxidative stress and related diseases.
Polyether antibiotics include lasalocid, maduramicin, monensin, narasin, salinomycin, and semduramicin. They are used exclusively in veterinary medicine as antibacterials and to prevent coccidiosis. These ionophores bind and transport metal ions across cell membranes, disrupting ion gradients in bacteria and protozoa and ultimately exhausting their energy, leading to cell death. They were discovered through fermentation of various Streptomyces and Actinomadura bacteria between 1951-1988 and are most effective against gram-positive bacteria and coccidia.
Copper Nanoparticles and Antioxidant Stress: Problem Makers or Solvers?_ Cri...CrimsonpublishersNTNF
Copper nanoparticles (NPs) have various applications but also pose environmental concerns. They can act as both problem makers and problem solvers. As problem makers, copper NPs may accumulate in the environment and cause toxicity in plants and animals over the long term. However, they also show promise as problem solvers by demonstrating antibacterial properties useful for wound dressings, and potential antioxidant and antidiabetic effects. More research is still needed to fully understand the ecological effects of copper NP exposure and their long term impacts on human health before their widespread use can be considered safe.
Ionophores are lipid-soluble compounds that form complexes to transport ions across biological membranes. They play an important role in improving livestock and poultry health and feed efficiency. Ionophores are produced by microorganisms and act by increasing the permeability of cell membranes to specific cations. Common ionophores used in animal feed include monensin, lasalocid, and salinomycin.
This document summarizes the key points from a meeting discussing the role of reactive oxygen species (ROS) in physiological processes. The meeting highlighted that ROS produced during moderate exercise are beneficial, not detrimental, as they promote muscle adaptation, endurance performance, and antioxidant defenses. However, excessive ROS from exhaustive exercise can damage cells. The discussion reconsidered definitions of oxidative stress and antioxidants, noting that ROS also have important signaling functions and that mild oxidative stress can trigger protective responses. More research is still needed to fully understand ROS regulation and when levels become harmful versus beneficial.
Schiff bases are compounds containing an imine or azomethine (-C=N-) functional group formed through condensation reactions between primary amines and carbonyl compounds. They have a wide variety of applications including as catalysts, pigments, dyes, polymers stabilizers, and in organic synthesis. Schiff bases also exhibit biological activities such as antimicrobial, anticancer, anti-inflammatory, and more. Transition metal complexes of Schiff bases have particularly shown potential as antimicrobial drugs and DNA binding agents. Due to the lone pair of electrons on nitrogen, Schiff bases have basic properties and can form insoluble salts through reactions with strong acids.
PPT on Protective Activity Of Certain Important Antioxidant Naveen K L
This document categorizes and describes various antioxidants. It discusses how antioxidants are classified based on their mode of action, location, and solubility. The major groups of antioxidants found in plants are enzymes, minerals, low and high molecular weight compounds, vitamins, hormones, and essential oils. Antioxidants play an important biological role in boosting the immune system, preventing neurodegenerative disorders, and promoting cardiovascular health. They can also be used therapeutically for conditions like Alzheimer's, cataracts, diabetes, and skin aging.
This document discusses essential plant nutrients and how they are classified. It outlines that 17 elements are considered essential for plant growth according to specific criteria. These elements can be classified based on their concentration in plants as either macronutrients, which are needed in larger quantities, or micronutrients, which are needed in smaller amounts. They can also be classified into four groups based on their biochemical behavior and physiological functions in plants. The four groups include elements that are major constituents of organic materials, involved in biochemical reactions, present in free ionic states or adsorbed to organic anions, or predominantly present as chelates.
Antioxidants /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Defence mechanism of antioxidant in Human BodyImad Khan
This document summarizes the antioxidant defense mechanism in the human body. It discusses what free radicals are and their main sources, as well as the antioxidant defense system that protects the body from free radical damage. The defense system includes antioxidant compounds and enzymes that act at different levels - prevention, interception, and repair - to neutralize free radicals. Some key antioxidant compounds and their roles are also described.
Acute Toxicity and Bioaccumulation Patterns of Lead and Zinc in Juveniles of ...iosrjce
Acute toxicity of lead and zinc salts (Pb(NO3)2 and ZnCl2) and their bioaccumulation patterns in
juveniles of Clarias gariepinus was investigated. ZnCl2 with a 96hr LC50 value of 15.301mg/l was found to be
more toxic than Pb(NO3)2 with a 96hr LC50 value of 51.516mg/l. ZnCl2 was bio-accumulated at a faster rate
in the gills and flesh of the fish than Pb(NO3)2 . The amount of ZnCl2 and Pb(NO3)2 bio-accumulated reduced
as the experiment proceeded. Higher levels of ZnCl2 were recorded in the gills than in the flesh of the juvenile
fishes. Essential heavy metals can be more toxic to aquatic organisms than non essential heavy metals when the
former is present in high enough concentrations. Water chemistry, speciation and bio-availability of heavy
metals in surrounding media are major factors that determine rate of accumulation in aquatic organisms.
This document discusses reactive oxygen species (ROS), antioxidants, and their roles in various disorders. It begins by defining ROS as unstable molecules that can damage cells, and listing their sources. ROS are necessary in small amounts but can cause issues in excess. Antioxidants help neutralize ROS and prevent oxidative damage. The document then examines the roles of ROS and antioxidants in specific disorders like diabetes, cardiovascular disease, chronic fatigue, cancers, pregnancy complications, and male infertility. It provides treatment options like antioxidant supplementation to help control ROS levels and reduce related disease complications.
This document provides the front matter, including title page, dedication page, and contents page, for a book titled "Antioxidants in Human Health and Disease". The book is edited by Tapan K. Basu, Norman J. Temple, and Manohar L. Garg and contains 27 chapters contributed by various authors on topics related to antioxidants and their role in human health and disease. The book is published by CABI Publishing and copyrighted in 1999.
This document summarizes key concepts from chapters 6-8 of a microbiology textbook including:
- The essential nutrients required by microbes including carbon, hydrogen, oxygen, nitrogen, phosphorus, and sulfur.
- The chemical composition of E. coli and what microbes use as energy and carbon sources, categorizing them as autotrophs and heterotrophs.
- The processes of osmosis, diffusion, and endocytosis that transport substances into and out of cells.
- Temperature categories for microbes like psychrophiles, psychrotrophs and how gases like oxygen and carbon dioxide influence microbial growth.
Reactive oxygen species and anti-oxidantsPeriowiki.com
This document discusses reactive oxygen species (ROS) and antioxidants. It begins with a brief history of the discovery of oxygen, free radicals, and their role in biology. ROS are classified and sources both endogenous and exogenous are described. The document outlines the origins and formation of ROS, as well as their beneficial roles in physiological functions and microbial destruction. However, excessive ROS can also cause tissue damage through lipid peroxidation and DNA damage. The body's antioxidant defense systems and how ROS levels impact periodontal health are examined. The conclusion discusses measuring ROS and antioxidants.
The document discusses drug delivery and amino acid chelated minerals. It notes that amino acid chelates have higher bioavailability than inorganic minerals due to resisting precipitation in the intestinal tract. It then summarizes several SKP Pharma products that use amino acid chelated minerals, including Calcifer for anemia and bone health, Osteoforte for bone health, and GlucoTin DS for joint support.
This document discusses minerals and their classification as major, trace, organic, or inorganic. It describes how minerals can be chelated to amino acids to form organic complexes that have greater absorption and bioavailability compared to inorganic minerals. The document provides examples of studies that demonstrate improved production outcomes, such as higher milk yield and quality, when animals are supplemented with organic chelated minerals rather than inorganic minerals.
This study investigated the potential inhibitory effects of different inorganic and organic sources of iron, zinc, copper, and manganese on the activity of three commercially available phytases from Aspergillus niger, Escherichia coli, and Peniophora lycii. Organic sources tested included proteinates, glycinates, polysaccharide complexes, and amino acid chelates. The results showed a highly significant relationship between phytase inhibition, trace mineral type and source, and mineral concentration. Proteinate mineral sources were generally less inhibitory than other sources. Different chelate sources demonstrated varying abilities to inhibit phytase activity.
The human body contains elements that can be classified as
abundant elements trace elements
What are the trace elements
Essential trace element
Biological Significance of Trace Elements
This document discusses the nutrient requirements of microbes. It notes that carbon, hydrogen, and oxygen requirements are often satisfied together through organic molecules that serve as carbon sources. These molecules can also serve as energy sources if they are reduced. Nitrogen, oxygen, hydrogen, phosphorus, and sulfur are also important nutrient sources for microbes. Some microbes can use inorganic sources like carbon dioxide, nitrates, sulfates and phosphates while others require organic sources or growth factors obtained from other organisms. The document outlines the various roles of these elements in microbial metabolism and biochemistry.
This document summarizes a study that analyzed levels of trace metals in Moringa oleifera leaves using atomic absorption spectroscopy. The study found that Moringa oleifera accumulates metals in the order of Nickel > Copper > Manganese. Specifically, the levels of copper, manganese and nickel in the leaves were determined to be 2.866 mg/kg, 1.1050 mg/kg and 3.2002 mg/kg respectively. The levels of metals found were generally below World Health Organization and Food and Agriculture Organization maximum permissible limits.
This document provides information about a lecture on essential and non-essential elements given by Prof. G.M. Dongare. It discusses macro and micro elements, and provides biological significance and functions of important metal ions like sodium, potassium, calcium, iron, cobalt, copper, zinc, and chlorine. It also summarizes the structure and function of hemoglobin, myoglobin, and chlorophyll.
Importance of transition metals in human bodyARUNIMAMISHRA11
Transition metals like iron, magnesium, zinc, cobalt, copper, nickel, molybdenum, and chromium are essential trace elements that play important roles in human health and biology. They are sequestered into metalloprotein complexes in the body which allows their properties to be controlled and directed as needed, while minimizing their ability to generate harmful reactive oxygen species. Transition metals are key components of many enzymes and proteins involved in processes like oxygen transport, DNA binding and replication, and cell signaling. While necessary in small amounts, maintaining appropriate levels of transition metals is important as deficiencies or toxicities can impact cellular functions and health.
Essential and non-essential elements/types of essential elements-Bulk and trace elements/ Some important essential elements/their uses / role in biological processes.
Prepared for my college-Kanya Maha Vidyalaya,Jalandhar.
ABSTRACT- Aquatic organisms have been considered to concentrate metals several times greater than environmental levels. Fishes have been used for many decades to evaluate the pollution status of water and thus considered as excellent biological indicator of heavy metals in aquatic environments. Heavy metals are natural tress components of the aquatic environment, but their levels have increased due to domestic, industrial, mining and agricultural activities. These heavy metals when accumulated in the fish tissues, they damage and weaken the mechanisms concerned leading to physiological, pathological and biochemical changes. The lead is non essential element while cobalt is an essential element for living organisms but its presence in fresh water in higher concentration are toxic to organism’s brain, liver, ovary, kidney and gills of the fish. The present study was aimed to investigate the changes due to two heavy metals (lead & cobalt) on the activity of the antioxidant enzyme, Catalase (CAT), Reduced glutathione (GSH), and Lipid peroxidation (LPO) in the brain of Danio rerio during 5, 10, 15 and 20 days of exposure period. For this study adult fishes were exposed to four different concentrations viz., 20, 30, 40 and 50 mg/l of cobalt and 5, 9, 13, and 17 mg/l of lead. Key-words- Zebrafish, Lead, Cobalt, Catalase, LPO, Glutathione, Heavy metals
This document discusses factors affecting the bioavailability of minerals in animals. It defines bioavailability and describes several methods for estimating mineral bioavailability and requirements, including absorption studies, growth responses, bone development assessments, tissue accumulation of minerals, and the use of isotopes. Common factors that can influence bioavailability are also outlined, such as deficiencies increasing absorption and cooking or processing altering mineral forms. Specific details are provided on how various factors affect the bioavailability of different minerals like calcium, iron, copper, iodine, and selenium.
This document summarizes essential and non-essential elements in biological systems. It defines essential elements as those required for life that cause death or malfunction if absent. Examples include oxygen, hydrogen, nitrogen, calcium and phosphorus. Non-essential elements do not play a positive role if absent. The document further describes essential elements as either bulk elements, which are found at higher concentrations, or trace elements, which are needed at very low concentrations. It provides sodium, potassium, calcium, magnesium, iron, copper, cobalt, iodine, fluoride and zinc as examples of essential bulk and trace elements and describes their roles in biological processes. The document also discusses porphyrins, metalloporphyrins like heme and chlor
This document discusses iron deficiency anemia, including its causes, prevalence, diagnosis, and management. Some key points:
- Iron deficiency is the most common micronutrient deficiency globally, affecting over 1 billion people. It ranges from mild iron deficiency to severe anemia.
- Those most at risk include infants, children under 5, children of school age, and women of childbearing age. The prevalence of anemia is highest in South Asia, Africa, and the Middle East.
- Causes include inadequate iron intake, high intake of inhibitors like phytic acid, hookworm infection, blood loss, and high fertility rates in women. Diagnosis involves clinical signs, hemoglobin levels, and other lab
Importance of zinc supplementation in layersOssama Motawae
Zinc plays many important roles in poultry nutrition and health. It is a component of enzymes involved in metabolism. Zinc deficiency can cause reduced growth, bone problems, poor feathering, and increased mortality in chickens. It also decreases immune function. Zinc is important for reproduction and development. While zinc is found in many foods, its bioavailability varies. Chelated zinc sources are better absorbed than inorganic sources. Proper zinc supplementation is important for optimal poultry performance and health.
This document discusses minerals in the human body. It notes that minerals are inorganic substances found in all body tissues and fluids, and serve important functions. The major minerals found in the body are calcium, phosphorus, potassium, sulfur, sodium, chloride and magnesium, comprising 90% of total mineral content. Minerals are absorbed from foods and their levels regulated by hormones and excretion to maintain dynamic equilibrium. The document lists the approximate amounts of various minerals in the adult body and their general functions.
Agricultural production systems are adapting operations to meet the increasing demand for wholesome and affordable food. Attention has focused on the long-term impact on ecosystems of both crop and animal production. With reference to animal agriculture, concerns have been expressed about the concentration of minerals in manure and its subsequent effect on soil mineral content and phytotoxicity.
This document summarizes a study that evaluated the reactivity of nanoparticles in the human digestive system. Specifically, it investigated the dissolution of copper and iron nanoparticles in simulated digestive fluids, and the ability of various nanoparticles to induce lipid oxidation in these fluids. Key results include: 1) Gastric fluid most readily dissolved copper and iron nanoparticles compared to other digestive fluids. 2) All nanoparticles induced some level of lipid oxidation, with nanoiron causing the most oxidation across all fluids. 3) The reactivity of nanoparticles differed between particle types and digestive fluids. This suggests nanoparticles may react in the digestive system and pose potential health risks.
1) Metal toxicity or metal poisoning refers to the toxic effects of certain metals in excessive amounts or certain chemical forms. Some metals are toxic when they form soluble poisonous compounds.
2) Arsenic contamination of groundwater is a major problem in Bangladesh, exposing millions of people. Arsenic is a metalloid that is toxic in its inorganic forms, especially trivalent arsenite which has a slow excretion rate.
3) The factors influencing metal toxicity include the metal properties like solubility and ligands, as well as environmental factors like pH, temperature, and organic substances present. Arsenic toxicity is linked to its interference with cellular respiration and sulfhydryl groups in proteins.
The document discusses solid waste management and composting. It explains that composting is a process where organic waste materials are broken down by microorganisms into a stable humus-like material called compost. Composting reduces the volume of waste and provides nutrients for plant growth. It can be done aerobically, using oxygen, or anaerobically, without oxygen. During aerobic composting, microbes break down organic compounds into carbon dioxide, nitrites, and nitrates.
RELATION BETWEEN EARTH, MOON, MARS AND A GIANT IMPACT DVS BioLife Ltd
It is believed that there was a Giant Impact causing formation of Pacific ocean and an astral body. General belief is Mars collided and Moon formed.
In this document, it is proposed that Moon has collided and Mars formed.
It is for the scientific community to credit or discredit this theory
Probiotics are live microorganisms that are similar to beneficial microorganisms found in humans. They are generally recognized as safe and help balance intestinal microbiota, enhancing health and boosting the immune system. The gut contains trillions of microorganisms, especially in the large intestine. Probiotics were first introduced in the early 20th century and are thought to benefit the host by improving microbial balance and inhibiting pathogens. Modern research investigates specific health effects of probiotics such as treating diarrhea and inflammatory diseases.
Somalatha and its most probable candidates_ a Review by Vijayaraghavan Gonuguntla in his book "Comprehensive Indian Medicinal Plants Vol i pages 207 to 225 published by Studium Press, Houston
Meat preservation without using chemical preservatives, which are generally carcinogenic or possess health risk factors in a natural way employing GRAS, non GM and Naturally occuring Microbes
The document discusses using algae for wastewater treatment. It notes that algae can efficiently treat wastewater by removing nutrients, heavy metals, and pathogens. This allows the treated water to be safely used for irrigation, reducing freshwater usage and pollution of waterways. Algae treatment in oxidation ponds also produces algal biomass that can be converted to biofuels or other products. The document provides examples of how different algae species effectively remove various wastewater contaminants like nitrogen, phosphorus, and COD. Algae wastewater treatment is seen as a more cost-effective and environmentally friendly alternative to conventional wastewater treatment methods.
IMPROVING BUFFALO MILK FOR FEEDING NEONATALS AS A REPLACEMENT OF MOTHER'S MILKDVS BioLife Ltd
The document discusses developing a breast milk substitute called MIMIC-BM made from buffalo milk. It aims to resemble human breast milk by making buffalo milk more compatible and functional. The need arises when mothers cannot breastfeed for medical reasons, poor lactation, or lack of availability. The document provides nutritional analyses of human milk, animal milks like cow and buffalo milk, and reviews the establishment of infant gut microbiota from breastfeeding versus formula feeding. It also discusses digestion in neonates and their nutritional requirements.
This document discusses proteases and their role in digestion in poultry. It begins by explaining that animals must obtain some amino acids from their diet as they lack the necessary enzymes to synthesize them. It then describes how ingested proteins are broken down through digestion involving acid and protease enzymes. The document provides classifications and examples of different types of proteases. It discusses how proteases break down proteins, fats, and carbohydrates at different pH levels along the gastrointestinal tract. The document also notes some anti-nutritional factors found in various feed ingredients and how proteases can help degrade them to improve digestibility.
This document discusses enzymes and their role in digestion. It provides information on different types of enzymes including cellulase, protease, lipase, and others. It describes what substrates each enzyme acts on and the end products produced. It also discusses various feed ingredients and their anti-nutritional factors, as well as the regions of the GI tract and enzymes involved in digestion.
This document discusses the use of poultry litter as a feed ingredient for livestock. It provides a history of regulations around using poultry litter in animal feed in the US, beginning with an FDA ban in 1967 over safety concerns, which was later reversed. In the mid-2000s, the FDA again considered banning litter use due to mad cow disease risks but ultimately decided a ban was unnecessary. The document also provides several citations and studies on using litter in poultry and cattle feed and the effects on animal growth and performance.
This document summarizes a study on the effect of hen age on fertility. The study found that older hens had decreased sperm penetration and fertility compared to younger hens, even when inseminated with similar numbers of sperm. There are a few potential reasons for this: 1) older hens may release sperm from storage more readily or in larger numbers; 2) older hens have smaller sperm storage areas due to increased weight; 3) sperm may remain viable for less time when stored in older hens; 4) older hens may produce fewer sperm receptor sites on eggs. The results indicate that reduced fertility in older flocks is partly due to physical and physiological changes in hens with age.
This document provides information about alternatives to chemotherapy for cancer treatment. It discusses chemotherapy drugs and their mechanisms of action. Additionally, it explores the potential role of unusual plant derivatives and microbes in cancer diagnosis, treatment and minimizing recurrence. The document contains a lengthy list of over 350 common cancer drugs used in chemotherapy.
TREATING Cattle dung for use as manure or poultry feeding stuffDVS BioLife Ltd
This document discusses methods for processing cattle dung. It begins by providing background on changes in livestock practices, including the rise of confined animal feeding operations that produce large volumes of manure slurry. Key issues with slurry include ammonia emissions, odors, and pathogens. The document then evaluates methods for processing cattle dung, including composting and converting it into a livestock feed ingredient to recycle nutrients. It provides details on the chemical composition and energy content of cattle manure and analyzes factors that influence emissions and degradation.
MastitisCare is a formulation used to control subclinical mastitis in dairy cows. It can also be used as an adjunct to conventional mastitis therapy involving antibiotics. Mastitis is caused by bacteria and impacts animal welfare and milk quality. MastitisCare contains minerals, probiotics, organic acids, and vitamins that can help prevent and treat mastitis as an alternative to antibiotics. It is applied topically to the udder and surrounding areas to control mastitis without the need for withdrawal times.
This document discusses methods for protecting orchards and vineyards from frost damage. It begins by describing how cold temperatures can damage crops in winter months. It then discusses various frost protection methods including shelter belts, covers, and heating systems. Specific systems mentioned include overtree and undertree sprinklers, heaters, wind machines, and evaporative cooling. Key considerations for selecting a protection system include the crop, location, costs, and weather conditions. Maintaining adequate water supplies and distribution is also important for methods using water like sprinklers. The document provides details on estimating heat outputs and water needs for different systems. Overall it aims to help farmers choose effective and economical frost protection.
The document discusses sodium chloride (common salt) and its replacement Saltex. It provides background on common salt, including its properties, roles in the body, absorption, and regulation. It notes that excess salt consumption is linked to several health conditions like hypertension. While salt is essential in small amounts, reducing sodium chloride levels in foods is challenging. The document then proposes ammonium chloride as a probable safe alternative to sodium chloride for its properties and physiological roles.
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Colion p
1. COLION_P
Index
1. PROLOGUE
2. INTRODUCTION
3. MAGNITUDE OF PHOSPHATIC FERTILIZER
PRODUCTION AND USE
4. ENVIRONMENTAL POLLUTION BY PHOSPHATIC
FERTILIZER INDUSTRY
5. NEED FOR A NOVEL PHOSPHORUS
NUTRIENTSUPPLEMENTATION
6. HOW CAN THIS BE ACHIEVED?
7. MODE OF ACTION OF COLION_P
8. SALIENT FEATURES OF COLION_P
9. RECOMMENDED DOSE:
10. PROXIMATE ANALYSIS:
11. REFERENCES
2. PROLOGUE
ABOUT
INORGANIC/ ORGANIC/CHELATED/ PROTEINATED/ NANO MINERALS
Conventional animal nutrient supplements including
A) Minerals
B) Amino acids
C) Vitamins
D) Drugs
have certain specific inherent drawbacks like
1) Poor bio-absorbability
2) Toxicity
3) Unpalatable taste
4) Poor solubility
5) High bio-absorption inhibiting activity (High reactivity)
Science long back recognized that the body must have certain minerals to
accomplish its work and preserve its health. However, recently Modern Science
conceives that these minerals must be in their Chelated, Proteianated, Organic,
Colliodal or Nano state to do the consumer any use at all; based on the following
observations.
1. Minerals are inorganic as they exist naturally in the soil and water.
2. Minerals are organic as they exist in plants and animals.
3. Only plants can transform inorganic minerals into organic minerals.
4. Animals must eat plants or plant-eating animals to obtain their organic minerals.
5. Inorganic minerals are useless and injurious to the animal organism.
Minerals and mineral mixes and premixes used in animal feed can contain
contaminants such as dioxin and various heavy metals. Some mineral mixes and
premixes are by-products or co-products of industrial metal production and can
become contaminated. For example, mineral mixes containing zinc oxide obtained
from brass production have been found to have high levels of dioxin contamination.
FDA has issued an alert to the feed industry warning against the use of mineral mixes
and premixes that are by-products or co-products of industrial metal production
(FDA CVM Update, 2003).
EPA is aware that hazardous wastes are sometimes recycled as nutritional
supplements in animal feed preparations but does not necessarily consider this use
3. to constitute disposal of hazardous waste. For example, zinc oxide reclaimed from
emission control dust from electric arc furnaces is a listed hazardous waste, but EPA
permitted it to be used as a nutritional feed supplement for animals
(EPA, 1994).
Minerals may also contain heavy metal contaminants such as lead, arsenic,
cadmium, and mercury. AAFCO lists 133 different mineral products used as feed
ingredients, and the “typical” levels of these contaminants in mineral feed
ingredients. Lead is considered only “moderately toxic” by the American Association
of Food Control Officials (AAFCO), and the maximum tolerance in complete feed is
30 ppm.
Because inorganic minerals and organic minerals have the same chemical
compositions, they were being treated as same, for a long time by the early
nutritionists. The mineral, iron, in the bloodstream has the same chemical
composition as the mineral, iron, in a nail—iron is iron, after all. However, only of
late, nutritionists visualized the differences between these two forms of iron.
Although there was a nutritive similarity between Chelated, Proteinated, Nano,
Colloidal, Organic and Inorganic minerals, each of these will have different impacts
on the performance of the Animals.
It is necessary that the minerals in the soil be elaborated into organic compounds by
the plant before they can be assimilated by the animal or human body. The various
mineral compounds produced synthetically differ in their structure and in the
relative positions of their component molecules than those produced in the plant.
Over sixty years ago a German scientist named Abderhalden conducted a series of
experiments comparing how several species absorbed different forms of iron. He
found that animals fed with food poor in iron, plus in addition of inorganic iron, were
unable in the long run to produce as much hemoglobin as those, receiving a natural
iron-sufficient diet.
While the inorganic iron may be absorbed into the body, it is not utilized in the
formation of hemoglobin, but remains unused within the tissues. Abderhalden also
concluded that any apparent benefit of the inorganic iron resulted from its
stimulating effect.
Chemically, it is true that iron in the bloodstream and iron in nails are the same and
that calcium in rocks (known as dolomite) is identical to calcium in the bones.
However, it is a grave error to believe that the body can digest and assimilate and
utilize powdered nails and crushed rocks.
The word chelate is derived from the Greek word meaning "claw". Technically
chelates hold trace elements in suspension while in transit.
4. A mineral amino acid chelate is composed of an amino acid that has two or more
donor groups combined with the mineral so that one or more rings are formed, with
the mineral being the closing component of this heterocyclic ring. Chelate structures
contain covalent bonds which give these chelates properties that are much different
than ionically bonded mineral salt forms. Mineral amino acid chelates are bidentate
(the mineral is attached at two ends of amino acid ligand), and have a ring in their
structure, while mineral complexes are unidentate (mineral is attached at one end of
its ligand) with no ring structure. It has been shown that a bidentate (chelated)
glycino group absorbs at the IR wavelength of 1643 cm-1, an ionized unidentate at
1610 cm-1, and a unionized unidentate at 1710 cm-1. In addition, it has been shown
that the carboxyl group in the amino acid glycine absorbs at the band of infra-red
light of 504 cm-1. The degree of absorption at this band segment has been shown to
diminish as the amount of bound glycine increases in a sample.
The term “organic mineral” refers to a variety of compounds including metal-amino
acid complexes, metal amino chelates, metal proteinates, metal-polysaccharide
complexes, metalyeast complexes, and metal-organic acid complexes. (Patton, 1990)
An organic mineral is simply a combination of a metal ion with an organic ligand such
as amino acids, proteins, polysaccharides, yeast, or organic acids. Specifically, the
metal ion is bound to the organic ligand through multiple attachments (either ionic
or covalent) with the metal ion occupying a central position in the structure (Kincaid,
1989, Nelson, 1988). During organic mineral formation, the metal ion and organic
ligand act as mutual electron donors (ligand) and electron acceptors (metal cations)
forming a heterocyclic ring structure (Nelson, 1988). Generally, the metal ion is
attached to electronegative areas (two or more) on a ligand.
The minerals can be absorbed along with the amino acids as a single unit utilizing the
amino acid(s) as a carrier molecule. Therefore, the problems associated with the
competition of ions for active sites and the suppression of specific nutritive mineral
elements by others can be avoided.
Interest is also building in using organic trace minerals in place of a portion of the
feed inorganic mineral supplement in order to get maximum growth and health with
lower levels of mineral intake, thus lowering the amount of minerals excreted from
the birds
(Bao et al., 2006).
Reducing mineral levels in litter placed on the land is an issue in many countries and
lower levels of complexed trace minerals may aid in reducing litter mineral excess.
A number of minerals have been shown to play crucial roles in broiler health and
organic trace minerals have been shown to have a role in boosting cellular and
humoral immunity in broilers. Organic zinc compounds have shown benefits in
improving immunity in birds
(Pimental et al., 1991a; Kidd et al., 1994).
5. In addition, chicks hatched from breeder hens fed organic trace minerals have shown
improved cellular and humoral immunity as well
(Kidd et al., 1992; Kidd et al., 1993).
The neutralization of stomach acid by pancreatic secretions into the intestine could
have negative consequences on mineral absorption because without the influence of
acid, some minerals may not remain dissociated and may bind with other
components present in the intestinal contents, rendering them unavailable for
absorption. One way this problem can be avoided is for the mineral to be
surrounded by “ligands,” or weak binding agents, which will protect the mineral
from stronger binding agents, even in the absence of acid, yet allow normal
absorption to occur.
SALIENT FEATURES OF PROTEINATED MINERALS
1. Counteracts Anti Nutritional Factors, which affect the mineral absorption
2. Health improvement (immune status, functional nutrition)
3. Improve the bioavailability of minerals
4. Improvement in the quality of animal produce (meat, milk, egg, wool etc.,)
5. Ensures over all animal welfare
6. Performance improvement
7. Protects environment by reducing metal pollution through excreta.
8. Reduces degenerative effect of trace minerals on vitamins in premixes and
feed.
9. Reduction of antagonism, interferences and competition among minerals.
6. THE CHELATE MOLECULAR WEIGHT: BELOW 800.
AVERAGE WEIGHT OF THE HYDROLYZED AMINO ACIDS IS AROUND 150-200
TECHNOLOGY FOR PREPARATION OF PROTEINATED MINERALS
HYDROLYSIS OF PROTEIN
↓
SEPARATION BY CENTRIFUGE
AND ULTRAFILTRATION
↓
CHELATION PROCESS
↓
REMOVAL OF UNBOUND MINERAL
MODE OF ACTION OF PROTEINATED MINERALS
1. STABLE IN RUMEN ENVIRONMENT & ABOMASUM
2. DELIVERED IN SMALL INTESTINE AS SUCH.
3. ABSORBED THROUGH ACTIVE TRANSPORT (MORE BLOOD LEVEL)
4. IT ACTS AS A BIOLOGICAL COMPLEX (MORE TISSUE LEVEL)
5. ENTER INTO DIFFERENT POOL
6. METABOLIZABLE IN DIFFERENTLY
(NEATHERY ET AL 1972) (PHARMACO-DYANAMICS NUTRIENT) (USING 65
ZN)
7. Strategies used to synthesize nanoparticles
Traditionally nanoparticles were produced only by physical and chemical methods. Some of
the commonly used physical and chemical methods are ion sputtering, solvothermal
synthesis, reduction and sol gel technique. Basically there are two approaches for
nanoparticle synthesis namely the Bottom up approach and the Top down approach.
In the Top down approach, scientists try to formulate nanoparticles using larger ones to
direct their assembly. The Bottom up approach is a process that builds towards larger and
more complex systems by starting at the molecular level and maintaining precise control of
molecular structure.
Physical and chemical methods of nanoparticle synthesis
Some of the commonly used physical and chemical methods include:
Sol-gel technique, which is a wet chemical technique used for the fabrication of metal oxides
from a chemical solution which acts as a precursor for integrated network (gel) of discrete
particles or polymers. The precursor sol can be either be deposited on the substrate to form
a film, cast into a suitable container with desired shape or used to synthesize powders.
Solvothermal synthesis, which is a versatile low temperature route in which polar solvents
under pressure and at temperatures above their boiling points are used. Under solvothermal
conditions, the solubility of reactants increases significantly, enabling reaction to take place
at lower temperature.
Chemical reduction, which is the reduction of an ionic salt in an appropriate medium in the
presence of surfactant using reducing agents. Some of the commonly used reducing agents
are sodium borohydride, hydrazine hydrate and sodium citrate.
Laser ablation, which is the process of removing material from a solid surface by irradiating
with a laser beam. At low laser flux, the material is heated by absorbed laser energy and
evaporates or sublimates. At higher flux, the material is converted to plasma. The depth over
which laser energy is absorbed and the amount of material removed by single laser pulse
depends on the material’s optical properties and the laser wavelength. Carbon nanotubes
can be produced by this method.
Inert gas condensation, where different metals are evaporated in separate crucibles inside
an ultra high vacuum chamber filled with helium or argon gas at typical pressure of few 100
pascals. As a result of inter atomic collisions with gas atoms in chamber, the evaporated
metal atoms lose their kinetic energy and condense in the form of small crystals which
accumulate on liquid nitrogen filled cold finger. E.g. gold nanoparticles have been
synthesized from gold wires.
8. NANO PARTICLES OF MINERALS
Current research is going on regarding the use of magnetic nanoparticles in the
detoxification of military personnel in case of biochemical warfare. It is hypothesized that by
utilizing the magnetic field gradient, toxins can be removed from the body. Enhanced
catalytic properties of surfaces of nano ceramics or those of noble metals like platinum and
gold are used in the destruction of toxins and other hazardous chemicals (Salata, 2005).
Photocatalytic activity of nanoparticles has been utilized to develop self- cleaning tiles,
windows and anti- fogging car mirrors.
The high reactivity of Titanium nanoparticles either on their own or when illuminated by UV
light have been used for bactericidal purposes in filters.
An important opportunity for nanoparticles in the area of computers and electronics is their
use in a special polishing process, chemical-mechanical polishing or chemical-mechanical
planarization (CMP), which is critical to semiconductor chip fabrication. CMP is used to
obtain smooth, flat, and defect-free metal and dielectric layers on silicon wafers. This
process utilizes slurry of oxide nanoparticles and relies on mechanical abrasion as well as a
chemical reaction between the slurry and the film being polished. CMP is also used in some
other applications, such as the polishing of magnetic hard disks.
Nanoscale titanium dioxide and zinc oxide have been used as sunscreens in cosmetics. The
primary advantage of using these nanoparticles is that they are well dispersed and transmit
visible light, acting as transparent sunblocks. On the other hand, inorganic sunscreens
appear white on the skin- a potential drawback.
The interaction of silver nanoparticles with HIV I has been demonstrated in vitro. It was
shown that the exposed sulfur binding residues of the glycoprotein knobs were attractive
sites for nanoparticle interaction and that the silver nanoparticles had preferential binding
9. to the gp 120 glycoprotein knobs. Due to this interaction, it was found that the silver
nanoparticles inhibited the binding of the virus to the host cells in vitro (Elechiguerra et al.,
2005).
Magnetic nanoparticles are also used in targeted therapy where a cytotoxic drug is attached
to a biocompatible magnetic nanoparticle. When these particles circulate in the
bloodstream, external magnetic fields are used to concentrate the complex at a specific
target site within the body. Once the complex is concentrated in the target, the drug can be
released by enzymatic activity or by changes in pH or temperature and are taken up by the
tumour cells (Pankhurst et al., 2003).
Porous nanoparticles have also been used in cancer therapy where the hydrophobic version
of a dye molecule is trapped inside the Ormosil nanoparticle. The dye is used to generate
atomic oxygen which is taken up more by the cancer cells when compared to the healthy
tissue. When the dye is not entrapped, it travels to the eyes and skin making the patient
sensitive to light. Entrapment of the dye inside the nanoparticle ensures that the dye does
not migrate to other parts and also the oxygen generating ability is not affected.
Alivisatos (2001) reported the presence of inorganic crystals in magnetotactic bacteria. The
bacterium was found to have about 20 magnetic crystals with a size range of 35- 120nm
diameter. The crystals serve as a miniature compass and align the bacteria with the external
magnetic field. This enables the bacterium to navigate with respect to the earth’s magnetic
field towards their ideal environment. These bacteria immobilize heavy metals from a
surrounding solution and can be separated by applying a low intensity magnetic field. This
principle can be extended to develop a process for the removal of heavy metals from waste
water.
Bioremediation of radioactive wastes from nuclear power plants and nuclear weapon
production, such as uranium has been achieved using nanoparticles. Cells and S layer
proteins of Bacillus sphaericus JG A12 have been found to have special capabilities for the
clean up of uranium contaminated waste waters (Duran et al., 2007).
Gold nanoparticles are widely used in various fields such as photonics, catalysis, electronics
and biomedicine due to their unique properties. E. coli has been used to synthesize gold
nanoparticles and it has been found that these nanoparticles are bound to the surface of the
bacteria. This composite may be used for realizing the direct electrochemistry of
haemoglobin (Du et al., 2007). p- nitrophenol is widely used in pesticides, pharmaceutical
industries, explosives and in dyes and is known to be a carcinogenic agent. Gold
nanoparticles have been synthesized using the barbated skullcap extract. The nanoparticles
synthesized by this method have been modified to the glass electrode and this has been
used to enhance the electronic transmission rate between the electrode and p- nitrophenol
(Wang et al., 2009).
Tripathy et al., (2008) reported the antibacterial applications of the silver nanoparticles
synthesized using the aqueous extract of neem leaves. The nanoparticles were coated on
cotton disks and their bactericidal effect was studied against E.coli. Duran et al., (2005)
reported the significant antibacterial activities of the silver nanoparticles synthesized using
Fusarium oxysporum.
12. INTRODUCTION
P is an important nutrient but the concentration of plant available P is generally
low (0.7 to 1.2% of total P) in arid soils. Further, nearly 70% of the applied
phosphate fertilizers is converted to -1 unavailable forms after application. Total
quantity of P in arid soils is >600 kg ha , but its availability is restricted. Thus,
application of phosphate fertilizers is a must for good crop.
Phosphate fertilizers are mainly synthesized from rock phosphate.
Phosphorus is a nonmetallic chemical element in group 15 (nitrogen family, formerly Va)
of periodic table; atomic number 15 atomic mass 30.9738; melting point ca 44.1 C (white);
boiling point ca 280 C (white); specific gravity 1.82 (white), 2.34 (red), 2.70 (black); valence
-3, +3, or +5 ; electronic config. 2-8-5 or 1s 22s 22p 63s 23p 3. The phosphorus molecule is
composed of four phosphorus atoms, P4. Phosphorus exists in a number of allotropic
forms [white (alpha and beta), red, black and/or violet] in the same physical state.
Phosphorus (P) is an essential mineral that is found in all cells within the bodies of every
living being.
Phosphorus is primarily found as phosphate.
The major building blocks of biology are covalent molecules comprising proteins,
polysaccharides, and nucleic acids.
The nucleic acids deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are polymers
based on phosphate ester monomers. The high-energy phosphate bond of ATP is the
major energy currency of living organisms. Cell membranes are composed largely of
phospholipids.
13. Metabolic functions of Phosphorous
Phosphorous provides the energy to cells to multiply and grow. The phosphate
ion present in the fertilizers get attached with adenosine moity to synthesize
adenosine triphosphate (ATP), the energy currency of cells.
Another biomolecule synthesised by the photosynthetic tissue contains phosphate ion,
called reduced nicotinamide adenine dinucleotide phosphate (NADPH) that drives the
fixation of carbon dioxide to form starch.
A variety of enzymatic activities are controlled by alternate phosphorylation and
dephosphorylation of proteins. The metabolism of all major metabolic substrates depends
on the functioning of phosphorus as a cofactor in a variety of enzymes and as the principal
reservoir for metabolic energy.
The ability of plants to acquire phosphate-P during deficiency conditions also
increases due to the synthesis of phosphate transporters. These biomolecules
also transport phosphite ions. Phosphite is rapidly absorbed and translocated
within the plant. However, the uptake is pH dependent and subject to
competition by phosphate ions. Phosphite in presence of a small quantity of
phosphate will not be recognised by phosphate transporters. Despite having
similar mobility, the phosphite is a non-metabolized form of phosphorous and
plants cannot use this as the sole source of phosphorous. Phosphate can be
assimilated into organic P compounds within minutes of uptake.
Antagonistic nature of the Minerals.
14. Phosphorous Deficiency Symptoms:
IN AGRICULTURE:
Enhanced root growth at the cost of shoot development
Increased root to shoot ratio
Low yields
Purple (anthocyanin pigment) colouration of leaves and petioles
Purple and weak stems
IN ANIMALS:
Phosphorus deficiency in cattle may cause symptoms related to reduced appetite,
including retarded growth rate of young cattle, low milk yield and impaired fertility.
Skeletal abnormalities associated with osteomalacia may appear as stiffness, reluctance to
move, shifting lameness, cracking sounds in joints when walking, an arched back and in
severe cases, spontaneous fractures.
15. Sources of Phosphorous:
Percentages of water-soluble and available phosphate in several common fertilizer
sources.
P 2 O 5 K
P 2 O 5 Source N Total Available
Water
Soluble*
- - - - - - - - - - - - - - - % - - - - - - - - - - - - - -
Superphosphate (OSP) 0 21 20 85 0
Concentrated Superphosphate
(CSP)
0 45 45 85
0
Monoammonium Phosphate
(MAP)
11 49 48 82
0
Diammonium Phosphate (DAP) 18 47 46 90 0
Ammonium Polyphosphate
(APP)
10 34 34 100
0
Rock Phosphate 0 34 3-8 0 0
COLION_P 0.95 45 45 100 0
*Water-soluble data are a percent of the total P2O5
Source: Ohio Agronomy Guide. Ohio Cooperative Extension Service Bull.472.
Pure anhydrous phosphoric acid is a white solid that melts at 42.35 °C to form a colorless,
viscous liquid.
Most people and even chemists refer to orthophosphoric acid as phosphoric acid, which is
the IUPAC name for this compound. The prefix ortho is used to distinguish the acid from
other phosphoric acids, called polyphosphoric acids.
Orthophosphoric acid is a non-toxic, inorganic, rather weak triprotic acid, which, when
pure, is a solid at room temperature and pressure. The chemical structure of
orthophosphoric acid is shown above in the data table.
Orthophosphoric acid is a very polar molecule; therefore it is highly soluble in water. The
oxidation state of phosphorus (P) in ortho- and other phosphoric acids is +5; the oxidation
state of all the oxygen atoms (O) is -2 and all the hydrogen atoms (H) is +1. Triprotic means
that an orthophosphoric acid molecule can dissociate up to three times, giving up an H+
each time, which typically combines with a water molecule, H2O, as shown in these
reactions:
H3PO4(s) + H2O(l) H3O+
(aq) + H2PO4
–
(aq) Ka1= 7.25×10−3
H2PO4
–
(aq)+ H2O(l) H3O+
(aq) + HPO4
2–
(aq) Ka2= 6.31×10−8
HPO4
2–
(aq)+ H2O(l) H3O+
(aq) + PO4
3–
(aq) Ka3= 3.98×10−13
The anion after the first dissociation, H2PO4
–
, is the dihydrogen phosphate anion. The
anion after the second dissociation, HPO4
2–
, is the hydrogen phosphate anion. The anion
after the third dissociation, PO4
3–
, is the phosphate or orthophosphate anion. For each of
16. the dissociation reactions shown above, there is a separate acid dissociation constant,
called Ka1, Ka2, and Ka3 given at 25°C. Associated with these three dissociation constants are
corresponding pKa1=2.12 , pKa2=7.21 , and pKa3=12.67 values at 25°C. Even though all three
hydrogen (H ) atoms are equivalent on an orthophosphoric acid molecule, the successive
Ka values differ since it is energetically less favorable to lose another H+
if one (or more)
has already been lost and the molecule/ion is more negatively-charged.
Phosphite is the fungicidal form of phosphorous that is not recognised by roots for uptake
and metabolism compared to the most
acceptable form called phosphate.
Although, phosphite can get oxidised by soil microbes to phosphates , but most recent
research has shown that phosphate reduced the root and shoot growth @ 24 kg/ha
(Barrett, 2002).
McDonald et al., 2001 found that phosphite is not utilized, but may trick phosphorus
deficient plants into not mimicking typical P deficiencies.
Wells et al., (2000) found that toxicity symptoms in alfalfa disappeared after 21 days.
Harris (2003) applied both phosphate and phosphite starter and foliar fertilizers on cotton
to compare its growth response to different P sources, and found that phosphite treated
plants were shorter compared to phosphate treated plants
Phosphites
should not be used as a substitute for plant – available , orthophosphate forms
of phosphorous . Phosphite is not immediately plant available and could lead to plant
toxicities in sensitive crops if high rates are applied . Phosphite damage appears amazingly
similar to glyphosate injury to crops.
MECHANISMS INVOLVED IN USING
SUPER PHOSPHATE IN SOIL.
The following article was written by Soiltech Soil Scientist, Dave McKie MAgSc (Hons)
1. Formation of Metal Phosphates
After Super has been applied and while it is being assimilated into the soil, dissolution-
precipitation processes are active. These involve both the formation of and subsequent
dissolving of phosphate precipitates. The fertiliser granules on the soil surface attract
moisture to them, resulting in chemical reactions which convert the soluble P within the
granules into phosphoric acid and a less soluble form of P, di-calcium phosphate. If the
prevailing soil conditions are acidic, and good levels of iron, aluminium, or manganese are
present, the P from the granules can be transformed into low solubility phosphates of
these metals. On the other hand, if the overall soil pH is neutral or alkaline, and adequate
levels of calcium are present, di-calcium phosphate can be further converted to an
insoluble tri-calcium phosphate, a compound similar to naturally occurring rock
phosphate. The latter scenario is believed to be more important to the overall
17. concentration of P in soil solution and thus also to plant P nutrition. Maintaining an overall
soil pH 6-6.5 lessens the likelihood of P precipitation and enhances P solubility.
During the assimilation process, an acid laden solution of low pH (1.5) moves out into the
soil. This is hostile to soil biology and, as a result, any biological life in the vicinity of the
disintegrating Super granule is wiped out. The impact of a fertiliser on soil biology is often
ignored when fertilizer is applied, yet soil biology is critical to the plant uptake of nutrients
from the soil. How long these
adverse acid conditions continue varies depending on other soil factors but eventually the
pH returns to levels close to that which existed before the fertiliser was applied.
The application of ammonium phosphate fertilisers also lowers pH during assimilation but
not as severely as Super does. Dicalcium phosphate and RPR fertilisers do not lower pH
when being assimilated and are thus “friendly” to the organisms living within the soil. The
latter fertilisers also release P more slowly and at a rate which more closely complements
plant P requirements.
Plants are unable to uptake all of the initial soil solution flush of P from Super.
Although Super lowers pH around the granules during the assimilation phase, this
situation is not permanent. In terms of overall soil pH, Super only slightly increases overall
soil acidity.
2. Absorption on Soil Particles
Sorption-desorption processes play a significant role in removing soluble inorganic P from
soil solution. Sorption occurs when P is removed from the soil solution and becomes
attached or fixed to the surface of soil particles. The impact of sorption varies depending
on the nature and extent of the particle and aggregate surfaces within the soil, but it is
generally worse in ash derived soils and other soils with a large content of amorphous or
poorly structured material. Such soils have a large available surface area to which P can
become fixed. Once the initial dissolution-precipitation reactions outlined above have run
their course, sorption-desorption processes become the main controller of soil solution P
concentration.
In time, and again depending on other prevailing soil factors, the P absorbed on these soil
surfaces either slowly penetrates deeper into the fabric of the soil material or becomes
buried beneath iron and aluminium oxide coatings which form on the surface of soil
particles. When this occurs the P is said to be “occluded”.
It is sometimes assumed that P fixation processes are always in the direction of loss of P
from soil solution. This is not correct. P is also released back into soil solution from soil
surfaces by the reverse process, desorption.
However, the P that has penetrated within soil particles or become occluded is only
released very slowly, and then not until surface absorbed P reserves have been depleted.
Release of penetrated P generally occurs too slowly to maintain soil solution P
concentrations at a high enough level for good plant growth.
3. Organic Immobilisation
Plants remove P from soil solution through their roots. In time, much of this P is returned
to the soil in plant litter, roots etc and in animal dung. Because dung is often deposited at
18. stock camps or in races etc, dung transfer can result in loses of P from the system, or at
best uneven re-distribution of
P. Obviously, some P is also lost in products/commodities that are removed from the farm.
P is constantly being cycled through soil organic matter. It is constantly being incorporated
into the plant and then subsequently released and made available again and so on.
Soil microbes, soil animals and other soil biological life also remove P from soil solution.
The life cycle of the microbes is usually quite short and hence, after they die, the P is
released again, generally with a much faster turn around than occurs with plant P.
Microbial P is returned to soil solution in both organic and inorganic soluble P forms. Just
like the P immobilised in plants, so also the P in soil organisms is recycled either through
other soil organisms, or back into plants or else it is subjected to the other processes
described earlier.
Soil biological life plays a key role in the mineralization of P from both organic and non
organic sources. In many pastoral situations, organic material can often comprise 50 – 80%
of the total P in the soil. Not all of this P is plant available or even becomes plant available
P in the short term.
However, the microbial biomass P is usually re-cycled quite rapidly when soil conditions
favour these organisms. For instance, in a typical soil with say 1000kg/ha of total P within
the plant rooting zone and a microbial biomass comprising say 3% of the total soil P, P re-
cycled from this source could supply roughly 15-24kg of P/yr or the equivalent of an
annual application of 250kg/ha of Super!
In a manner similar to the way soil solution P is subject to sorption-desorption processes
on the surface of soil particles, it can also become absorbed onto the surface of organic
matter particles within the soil. If conditions are favourable, significant amounts of P can
be immobilised in this way, especially as soils become more acid. The chemistry of organic
P is complex and not very well understood. Never the less, it is clear that under the
influence of soil microbial life, and in particular rhizosphere fungi, a portion of this organic
P is returned to soil solution.
As a general rule, there is often more organic P in soil solution than inorganic P. When it is
considered that the Olsen P test only assesses the inorganic plant available P fraction of
the soil, then it becomes clear that the Olsen P test may under-estimate plant available P
i.e. there may be much more P available than is commonly realised.
Because of the size and complexity of organic soil molecules, it is difficult to assess how
much of this soluble organic P is taken up by plant roots but clearly, organic P does
contribute to plant P nutrition.
19. MAGNITUDE OF
PHOSPHATIC FERTILIZER
PRODUCTION AND USE
Worldwide phosphate production for 2010 is expected to be roughly 176 million
tonnes per year. China, Morocco and the United States represent roughly 67% of
the global phosphate rock supply. Also, roughly 65% of worldwide reserves are
located in Morocco with China a distant second.
Evolution of fertilizer consumption between 2007/08 and 2010/11
(Adapted from Heffer and Prud’homme, 2012)
20.
21.
22. ENVIRONMENTAL POLLUTION
BY PHOSPHATIC FERTILIZER INDUSTRY
Phosphate Fertilizer Mining Waste. www.industrialscars.com
Effects of Fluoride Pollution
It is well known that where ever phosphate industries have had inefficient, or non-
existent, pollution control that has caused a very serious threat of Fluoride.
The Canadian Broadcasting Corporation (CBC) called the phophate industry a
“pandora’s box.” While the industry brought wealth to rural communities, it also
brought ecological devastation. The CBC described the effects of one particular
phosphate plant in Dunville, Ontario:
“Farmers noticed it first… Something mysterious burned the peppers, burned the
fruit, dwarfed and shriveled the grains, damaged everything that grew. Something in
the air destroyed the crops. Anyone could see it… They noticed it first in 1961. Again
in ’62. Worse each year. Plants that didn’t burn, were dwarfed. Grain yields cut in
half…Finally, a greater disaster revealed the source of the trouble. A plume from a
silver stack, once the symbol of Dunville’s progress, spreading for miles around
poison – fluorine. It was identified by veterinarians. There was no doubt. What
happened to the cattle was unmistakable, and it broke the farmer’s hearts. Fluorosis
– swollen joints, falling teeth, pain until cattle lie down and die. Hundreds of them.
The cause – fluorine poisoning from the air.”
Fluoride has been, and remains to this day, one of the largest environmental
liabilities of the phosphate industry. The source of the problem lies in the fact that
raw phosphate ore contains high concentrations of fluoride, usually between 20,000
to 40,000 parts per million (equivalent to 2 to 4% of the ore).
23. When this ore is processed into water-soluble phosphate (via the addition of sulfuric
acid), the fluoride content of the ore is vaporized into the air, forming highly toxic
gaseous compounds (hydrogen fluoride and silicon tetrafluoride).
In Polk County, Florida, the creation of multiple phosphate plants in the 1940s
caused damage to nearly 25,000 acres of citrus groves and “mass fluoride poisoning”
of cattle. It is estimated that, as a result of fluoride contamination, “the cattle
population of Polk County dropped 30,000 head” between 1953 and 1960, and “an
estimated 150,000 acres of cattle land were abandoned” (Linton 1970). According to
the former president of the Polk County Cattlemen’s Association:
“Around 1953 we noticed a change in our cattle… We watched our cattle become
gaunt and starved, their legs became deformed; they lost their teeth. Reproduction
fell off and when a cow did have a calf, it was also affected by this malady or was a
stillborn.”
In the 1960s, air pollution emitted by another phosphate plant in Garrison, Montana
was severe enough to be branded “the worst in the nation” by a 1967 National Air
Pollution Conference in Washington, D.C.
As in Polk County, and other communities downwind of fluoride emissions, the cattle
in Garrison were poisoned by fluoride. As described in a 1969 article from Good
Housekeeping:
“The blight had afflicted cattle too. Some lay in the pasture, barely able to move.
Others limped and staggered on swollen legs, or painfully sank down and tried to
graze on their knees… Ingested day after day, the excessive fluoride had caused
tooth and bone disease in the cattle, so that they could not tolerate the anguish of
standing or walking. Even eating or drinking was an agony. Their ultimate fate was
dehydration, starvation – and death.”
Litigation from Fluoride Damage
Damage to vegetation and livestock, caused by fluoride emissions from large
industry, has resulted, as one might expect, in a great deal of expensive litigation. In
1983, Dr. Leonard Weinstein of Cornell University, stated that “certainly, there has
been more litigation on alleged damage to agriculture by fluoride than all other
pollutants combined” (Weinstein 1983). While Weinstein was referring to fluoride
pollution in general, his comments give an indication of the problem facing the
phosphate industry – one of the most notorious emitters of fluoride – in its early
days.
So too does an estimate from Dr. Edward Groth, currently a Senior Scientist at
Consumers Union. According to an article written by Groth, fluoride pollution
between the years 1957 to 1968, “was responsible for more damage claims against
industry than all twenty (nationally monitored air pollutants) combined.”
The primary reason for the litigation against fluoride emitters was “the painful,
economically disastrous, debilitating disease” that fluoride causes to livestock
24. (Hodge & Smith 1977). As noted in a 1970 review by the US Department of
Agriculture (USDA),
“Airborne fluorides have caused more worldwide damage to domestic animals than
any other air pollutant” (Lillie 1970).
Another review on air pollution reached the same conclusion. According to Ender
(1969):
“The most important problem concerning damage to animals by air pollution is, no
doubt, the poisoning of domestic animals caused by fluorine in smoke, gas, or dust
from various industries; industrial fluorosis in livestock is today a disorder well
known by veterinarians in all industrialized countries.”
According to a review discussing “Fluorine toxicosis and industry”, Shupe noted that:
“Air pollution damage to agricultural production in the United States in 1967 was
estimated at $500,000,000. Fluoride damage to livestock and vegetation was a
substantial part of this amount” (Shupe 1970).
Scrubbing away the problem
Due to the inevitable liabilities that fluoride pollution presented, and to an
increasingly stringent set of environmental regulations, the phosphate industry
began cleaning up its act. As noted by Ervin Bellack, a chemist for the US Public
Health Service:
“In the manufacture of super-phosphate fertilizer, phosphate rock is acidulated with
sulfuric acid, and the fluoride content of the rock evolves as volatile silicofluorides. In
the past, much of this volatile material was vented to the atmosphere, contributing
heavily to pollution of the air and land surrounding the manufacturing site. As
awareness of the pollution problem increased, scrubbers were added to strip
particulate and gaseous components from the waste gas…” (Bellack 1970)
A 1979 review, published in the journal Phosphorous & Potassium, added:
“The fluorine compounds liberated during the acidulation of phosphate rock are now
rightly regarded as a menace and the industry is now obliged to suppress emissions-
containing vapors to within very low limits in most parts of the world… In the past,
little attention was paid to the emission of gaseous fluorine compounds in the
fertilizer industry. But today fluorine recovery is increasingly necessary because of
stringent environmental restrictions which demand drastic reductions in the
quantities of volatile and toxic fluorine compounds emitted into the waste gases.
These compounds now have to be recovered and converted into harmless by-
products for disposal or, more desirably, into marketable products” (Denzinger
1979).
A Missed Opportunity: Little Demand for Silicofluorides
Considering the great demand among big industry for fluoride chemicals as a
material used in a wide variety of commercial products and industrial processes, the
phosphate industry could have made quite a handsome profit selling its fluoride
25. wastes to industry. This was indeed the hope among some industry analysts,
including the authors of the review noted above (Denzinger 1979).
However, the US phosphate industry has thus far been unable to take advantage of
this market. The principal reason for this failure stems from the fact that fluoride
captured in the scrubbers is combined with silica. The resulting silicofluoride
complex has, in turn, proved difficult for the industry to separate and purify in an
economically-viable process.
As it now stands, silicofluoride complexes (hydrofluorosilicic acid & sodium
silicofluoride) are of little use to industry. Thus, while US industry continues to satisfy
its growing demand for high-grade fluoride chemicals by importing calcium fluoride
from abroad (primarily from Mexico, China, and South Africa), the phosphate
industry continues dumping large volumes of fluoride into the acidic wastewater
ponds that lie at the top of the mountainous waste piles which surround the
industry. In 1995, the Tampa Tribune summed up the situation as follows:
“The U.S. demand for fluorine, which was 400,000 tons, is expected to jump 25
percent by next year… Even though 600,000 tons of fluorine are contained in the 20
million tons of phosphate rock mined in Florida, the fluorine market has been
inaccessible because the fluorine is tied up with silica, a hard, glassy material.”
Of course, not all of the phosphate industry’s fluoride waste is disposed of in the
ponds. As noted earlier, the phosphate industry has found at least one regular
consumer of its silicofluorides: municipal water-treatment facilities. According to
recent estimates, the phosphate industry sells approximately 200,000 tons of
silicofluorides (hydrofluorosilicic acid & sodium silicofluoride) to US communities
each year for use as a water fluoridation agent (Coplan & Masters 2001).
Fluoridation:
According to Dr. J. William Hirzy, the current Senior Vice-President of EPA
Headquarters Union
“If this stuff gets out into the air, it’s a pollutant; if it gets into the river, it’s a
pollutant; if it gets into the lake it’s a pollutant; but if it goes right into your drinking
water system, it’s not a pollutant. That’s amazing… There’s got to be a better way to
manage this stuff.”
Recent Findings on Silicofluorides
Adding to Hirzy’s, and the EPA Union’s, concerns are three recent findings.
First and foremost are two recent studies reporting a relationship between water
treated with silicofluorides and elevated levels of lead in children’s blood (Masters &
Coplan 1999, 2000). The authors of these studies speculate that the silicofluoride
complex may increase the uptake of lead (derived from other environmental
sources, such as lead paint) into the bloodstream.
The second finding is the recent, and quite remarkable concession from the EPA, that
despite 50 years of water fluoridation, the EPA has no chronic health studies on
silicofluorides. All safety studies on fluoride to date have been conducted using
26. pharmaceutical-grade sodium fluoride, not industrial-grade silicofluorides. A similar
concession has also been obtained from the respective authorities in England.
The defense made by agencies promoting water fluoridation, such as the US Centers
for Disease Control, to the lack of such studies, is that when the silicofluoride
complex is diluted into water, it dissociates into free fluoride ions or other fluoride
compounds (e.g. aluminum-fluoride), and thus the treated water, when consumed,
will have no remaining silicofluoride residues (Urbansky & Schock, 2000).
This argument, while supported by a good deal of theoretical calculation is at odds
with a recently obtained and translated PhD dissertation from a German chemist.
(Westendorf 1975). According to the dissertation, not only do the silicofluorides not
fully dissociate, the remaining silicofluoride complexes could be more potent
inhibitors of cholinesterase, an enzyme vital to the functioning of the central nervous
system.
The third finding is that the silicofluorides, as obtained from the scrubbers of the
phosphate industry, contain a wide variety of impurities present in the process water
– particularly arsenic and possibly radionuclides. While these impurities occur at low
concentrations, especially after dilution into the water, their purposeful addition to
water supplies directly violates EPA public health goals. For instance, the EPA’s
Maximum Contaminant Level Goal for arsenic, a known human carcinogen, is 0 parts
per billion. However, according to the National Sanitation Foundation, the addition
of silicofluorides to the water supply will add, on average, about 0.1 to 0.43 ppb, and
as much as 1.6 ppb, arsenic to the water.
As noted by the Salt Lake Tribune,
“Those who had visions of sterile white laboratories when they voted for fluoride
weren’t thinking of fluorosilicic acid. Improbable as this sounds, much of it is
recovered from the scrubbing solution that scours toxins from smokestacks at
phosphate fertilizer plants.”
Gypsum Stacks & ‘Slime Ponds’
Fluoride-contaminated wastewater sitting on top of “gypsum stack.”To make 1
pound of commercial fertilizer, the phosphate industry creates 5 pounds of
contaminated phosphogypsum slurry (calcium sulfate). This slurry is piped from the
processing facilities up into the acidic wastewater ponds that sit atop the
mountainous waste piles known as gypsum stacks.
According to the EPA, 32 million tons of new gypsum waste is created each year by
the phosphate industry in Central Florida alone. (Central Florida is the heart of the
US phosphate industry). The EPA estimates that the current stockpile of waste in
Central Florida’s gypsum stacks has reached “nearly 1 billion metric tons.” (The
average gypsum stack takes up about 135 acres of surface area – equal to about 100
football fields – and can go as high as 200 feet.)
27. Radiation Hazard
It is sort of a misnomer, however, to call these stacks “gypsum” stacks. Indeed, if the
stacks were simply gypsum, they probably wouldn’t exist, as gypsum can be readily
sold for various purposes (e.g. as a building material). What can’t be readily sold,
however, is radioactive gypsum, which is about the only type of gypsum the
phosphate industry has to offer.
The source of the gypsum’s radioactivity is the presence of uranium, and uranium’s
various decay products (i.e. radium), in raw, phosphate ore. As noted by the Sarasota
Herald Tribune
“there is a natural and unavoidable connection between phosphate mining and
radioactive material. It is because phosphate and uranium were laid down at the
same time and in the same place by the same geological processes millions of years
ago. They go together. Mine phosphate, you get uranium.”
Phosphate ore can contain high concentrations of uranium, as evident by this sign at
IMC Agrico’s plant in Polk County.
While uranium, and its decay-products, naturally occur in phosphate ore, their
concentrations in the gypsum waste, after the extraction of soluble phosphate, are
up to 60 times greater.
The gypsum has therefore been classified as a “Naturally Occurring Radioactive
Material“, or NORM waste, although some, including the EPA, have questioned
whether this classification understates the problem. According to the Tampa
Tribune, the gypsum “is among the most concentrated radioactive waste that comes
from natural materials.”
It is so concentrated, in fact, that “it can’t be dumped at the one landfill in the
country licensed to take only NORM waste.”
Thus, according to US News & World Report, the EPA is currently “weighing whether
to classify the gypsum stacks as hazardous waste under federal statutes, which
would force the industry to provide strict safeguards” (to nearly 1 billion tons of
waste).
One of EPA’s main concerns with gypsum stacks centers around the fact that radium-
226 breaks down into radon gas. When radon gas is formed, it can become airborne,
leading to potentially elevated exposures downwind of the stacks. Such airborne
exposures are of particular concern to areas like Progress Village, Florida, where “a
new gypsum stack is rising a few hundred yards from a grade school.” According to
US News & World Report, there is evidence to suggest cancer rates downwind of the
stacks may be elevated:
“Some epidemiological studies suggest that lung cancer rates among nonsmoking
men in the phosphate region are up to twice as high as the state average. Acute
leukemia rates among adults are also double the average. An industry-sponsored
28. study of male phosphate workers, however, found lung cancer rates no higher than
the state average. There is no proof that mine wastes cause cancer, but the evidence
is worrisome.”
Will radioactive gypsum be added to roads?
With the growing realization that gypsum stacks represent a serious environmental
threat to Central Florida, both now and for generations to come, the phosphate
industry has been looking into ways of reducing the size of the stacks (and the size of
their liability.)
In an interesting parallel to fluoride, the phosphate industry is looking to turn its
gypsum waste into a marketable product: as a potential cover for landfills, as a soil
conditioner, and as a base material for roads.
As of yet, however, the EPA does not appear willing to relax its rules and lift its ban
on commercial uses of gypsum. According to the Tampa Tribune, “EPA’s limit for use
is 10 picocuries of radium per gram, well below the levels usually found in the
mounds.”
A recent statement from the EPA reads:
“Only two uses (for the gypsum) are permitted: limited agricultural use and research.
Other uses may be proposed, but otherwise the phosphogypsum must be returned
to mines or stored in stacks.”
Cold War Secrets & Worker Health
In Joliet, Illinois, it has only recently come to light that the local phosphate plant had
secretly produced some 2 million pounds of uranium for the US government in the
years 1952 to 1962. According to local newspaper reports, the cancer rates of people
who worked at the plant, especially “Building 55” where the uranium was processed,
are unusually high.
Today, with the Cold War over, it is becoming clear that workers in the phosphate
industry need special protection. According to a report from the European
Commission:
“Processing and waste handling in the phosphate industry is associated with
radiation levels of concern for workers and the public. The level of protection for
these groups should be more similar to the level of protection that is state of the art
in other industries, particularly the nuclear industry.”
Wastewater Issues
While the radioactivity of the gypsum stacks has probably been the key health
concern of the EPA, it is not the only one.
Resting atop the phosphate industry’s gypsum piles are highly-acidic wastewater
ponds, littered with toxic contaminants, including fluoride, arsenic, cadmium,
chromium, lead, mercury, and the various decay-products of uranium. This
29. combination of acidity and toxins makes for a poisonous, high-volume, cocktail,
which, when leaked into the environment, wreaks havoc to waterways and fish
populations. As noted by the St. Petersburg Times, “Spills from these stacks have
periodically poisoned the Tampa Bay environs. ”
One spill, in 1997, from a now-defunct gypsum stack in Florida, “killed more than a
million fish.”
“Strike the Alafia River off your list of fishing spots,” wrote one journalist after the
spill. “It’s gone, dead as a sewer pipe, killed by the carelessness of yet another
phosphate company.”
Today, the same gypsum stack which caused this particular spill, is considered by
Florida’s Department of Environmental Protection to be “the most serious pollution
threat in the state.” That’s because tropical rains over the past couple of years have
brought the wastewater to the edge of the stack’s walls.
As noted by the Tampa Tribune, “The gypsum mound is near capacity, and a wet
spring or a tropical storm could cause a catastrophic spill.”
To prevent such a spill, which was all but inevitable, the EPA recently agreed to let
Florida pursue “Option Z“: To load 500-600 million gallons of the wastewater onto
barges and dump it directly into the Gulf of Mexico.
The dumping of the wastewater into the Gulf represents the latest in a series of
high-profile embarrasments for Florida’s phosphate industry; one of the most
dramatic of which happened on June 15, 1994.
On that day, a massive, 15-story sinkhole appeared in the middle of an 80 million ton
gypsum stack. The hole was so big that, according to US News & World Report, it
“could be as big as 2 million cubic feet, enough to swallow 400 railroad boxcars.
Local wags call it Disney World’s newest attraction — ‘Journey to the Center of the
Earth.’”
But, as US News noted,
“there’s nothing amusing about it. The cave-in dumped 4 million to 6 million cubic
feet of toxic and radioactive gypsum and waste water into the Floridan aquifer,
which provides 90 percent of the state’s drinking water.”
(http://www.thelibertybeacon.com/2013/05/19/the-phosphate-fertilizer-industry-
an-environmental-overview-fluoride-is-poison/)
Thus it can be seen that processing Rock phosphate into super phosphates involves
heavy environmental pollution and is becoming a threat to Livestock and humans.
30. NNNEEEEEEDDD FFFOOORRR AAA NNNOOOVVVEEELLL PPPHHHOOOSSSPPPHHHOOORRRUUUSSS
NNNUUUTTTRRRIIIEEENNNTTT SSSUUUPPPPPPLLLEEEMMMEEENNNTTTAAATTTIIIOOONNN
Low utilization of native-P by crops and high fixation of applied P had been a major
concern in crop production for over three decades. Different approaches viz.
phosphorus solubilizing bacteria (PSB), phosphatase and phytase producing fungi
(PPF), organic acid producing microorganisms, and VAM have been tried in past to
address these problems.
But success of these phosphorus mobilizing microorganisms (PMM) had been
limited for two reasons
(a) Low soil organic carbon (SOC) which limit the energy supply to PMM
(b) High evaporation from surface soils which adversely affect the survivability of
PMM.
(http://www.cazri.res.in/naip/brochure.pdf#page=2&zoom=auto,-99,746)
NOW WE PROPOSE
1. TO REDUCE LEVEL OF USAGE OF PHOSPHATIC FERTILIZERS
AND THUS MINIMIZE PRODUCTION OF PHOSPHATIC FERTILIZERS
2. TO INSTILL MORE BIOAVAILABLE PROTEINATED PHOSPHOROUS
AND THUS EVEN REDUCE RESIDUAL PHOSPHORUS LEACHATES INTO
SURFACE WATERS
3. TO REDUCE QUANTITY OF LITTER WHEN USED IN ANIMALS
31. HHHOOOWWW CCCAAANNN TTTHHHIIISSS BBBEEE AAACCCHHHIIIEEEVVVEEEDDD???
Plants exude about 25 to 30% of the photosynthates through roots. These
exudates consist of low molecular weight amino acids, amino sugars, organic acids
and polysaccharides and can provide energy to PMM and C skeleton for synthesis
of exo-polysaccharides. Any attempt to increase proportion of root exudates
would logically result in yield reduction; therefore, we propose to increase
photosynthesis in crop plants to achieve higher root exudates.
Nano-particles of Mg, Zn, Fe and P are the structural component of enzymes
(phosphatases and phytase), polysaccharides and chlorophyll. They are known to
stabilize the enzyme complexes in plants. We aim on utilizing this property for
increasing photosynthesis that would most likely lead to higher exudation which in
turn would increase the energy supply and supply of C skeleton compounds to
PMM and exo-polysaccharide producing micro-organisms. This approach would
enable in breaking of existing barriers in utilization of native P and reduce
dependence on imported P fertilizers.
Most of the P in soil is bound as highly stable Ca-P, Fe-P, Al-P and as plant
unavailable inorganic form besides C-O-P ester bond in organic form. These bonds
can be solubilized/hydrolyzed by phosphatases, phytase enzymes and organic acid
produced by microorganisms viz. phosphorus solubilizing bacteria, phosphatase
and phytase producing microorganisms and arbuscular mycorrhizal fungi through
biochemical reactions. But this biochemical process is energy intensive. Total
energy availability in arid soils is low due to low SOC. As a consequence the
population, survivability and efficacy of phosphorus mobilizing microorganisms
(PSM) in soil is low.
Utilization efficiency of phosphatic fertilizers is very low due to their inversion to
insoluble forms in general and it is further aggravated in arid soils by higher
concentration of silicic acid and calcium carbonate. We propose to synthesize
nano-particles of rock phosphate and use them as fertilizer by direct application on
plant surface. This would avoid contact of P with soil to avert inversion and
increase utilization efficiency of fertilizer P by crops. Moreover, there would be no
competition with silicic acid and also no fixation by calcium.
(http://www.cazri.res.in/naip/brochure.pdf#page=2&zoom=auto,-99,746)
32. NOW WE OFFER COLION_P
IONISED PHOSPHOROUS EMBEDDED IN A MATRIX OF COLLOIDAL
AMINOACID LIKE L LYSINE, WHICH IS CONSIDERED AS AN ESSENTIAL
AMINOACID.
COLION_P is totally bioavailable and enters into plant system as a
bioencapsulated molecule in whole and results in no antagonisms.
Organic P content in COLION_P can replace ten folds inorganic P
supplements.
MMMOOODDDEEE OOOFFF AAACCCTTTIIIOOONNN OOOFFF CCCOOOLLLIIIOOONNN___PPP
Natural Ionised Phosphorus and Colloidal Protein successfully combined with a
biopolymer.
This blend has been delicately handled to ensure the full benefit of a boost to
metabolism of high performance ruminants, poultry, fish, prawn, agricultural crops
etc, in a safe naturally occurring manner.
This product is totally bioassimable as a whole without break up and will also
improve the performance of the microflora.
33. CCCOOOLLLIIIOOONNN___PPP
COLION_P is a non-phosphite phosphorous nutrient formulation to help harvest the best
crop.
COLION_P safely replaces Use of Dicalcium phosphate and Phytase in animal feeds.
In Agriculture, COLION_P can be conveniently applied through the drippers at early stages
of crops and through the leaves ( foliar ) during the fruiting and later stages of growth to
produce the best quality crop with higher yields.
In Animals it can be safely used either in feed or in drinking water.
COLION_P contains Phosphorous, Metabolites of Phosphorous Solubilising Bacteria,
Phytase and Phosphatase Enzymes, which is an unique combination.
When available P is considered
COLION_P replaces inorganic phosphorus sources like rock Phosphate and
Superphosphate.
Organic phosphorous content of 1 L COLION_P can replace 15 Kg Superphosphate.
Metabolites of the Microbes and enzymes impart efficiency to the plants to uptake the
insoluble Phosphorus available in the soil.
STUDY CONDUCTED
Combinations of trisodium phosphate with boric acid and sodium humate gave superior
results as compared to superphosphate (maximum productivity 74.7 t/ha). Use of
trisodium phosphate also obtained beetroot with the highest sugar (9.7%) and the lowest
nitrate (1232 mg/kg) contents.
(http://www.cababstractsplus.org/abstracts/Abstract.aspx?AcNo=20043146810)
34. SALIENT FEATURES OF CCCOOOLLLIIIOOONNN___PPP
100% BIOAVAILABILITY
100% WATER SOLUBLE PHOSPHOROUS
ABSORBED AND METABOLIZED MORE EFFICIENTLY.
ABSORBED BY DIFFERENT ROUTES THAN INORGANIC MINERALS.
ABSORBED BY THE AMINO ACID TRANSPORT SYSTEM.
BUILDS CRITICAL LEVELS OF PHOSPHOROUS
COST EFFECTIVE
DELIVERED IN A FORM SIMILAR TO THAT FOUND IN THE PLANT.
EASY TO ADMINISTER
HELPFUL IN THE CASES OF MALABSORPTION CONDITIONS
IMPARTS THE PLANTS ABILITY TO WITHSTAND PHOSPHORUS DEFICIENCY.
IMPROVED PLANT HEALTH
INCREASES LEVELS FOR ENERGY, WATER AND NUTRIENT HOLDING CAPACITY
INCREASES PASSIVE ABSORPTION BY INCREASING WATER AND LIPID SOLUBILITY
OF THE MINERAL NUTRIENT.
INCREASES THE ABILITY OF PLANTS TO RESIST PEST AND DISEASE ATTACK
MAKES THE PLANTS EFFICIENT TO UPTAKE THE ORGANIC P AVAILABLE IN THE SOIL.
MEETS THE DEMANDS OF MODERN PLANT GENOTYPES WITH HIGHER
REQUIREMENTS
MOST USEFUL IN STRESS CONDITIONS
MOVEMENT THROUGH CELL MEMBRANES.
NON-TOXIC TO THE PLANTS.
PROMOTES AVAILABILITY OF BOTH PHOSPHOROUS AND PROTEINS
REBUILDS TIRED NUTRITION THROUGH REMINERALISATION
REDUCES INPUT COSTS THROUGH EFFICIENCY
RESISTS DISEASES LIKE DOWNY MILDEW OF GRAPES, FRUIT ROT, ROOT ROT &
CITRUS GUMMOSIS, LATE BLIGHT OF TOMATO ETC.
STABLE AT A LOW PH.
WORKS WELL IN NEUTRAL AND LITTLE ALKALINE SOILS ALSO.
35. RECOMMENDED CROPS
Corn, Soy bean, Fruits, Vegetables, Rice, Sugar cane, Wheat, Cotton, Tobacco etc
RECOMMENDED ANIMALS
POULTRY, CATTLE, SHEEP, FISH AND PRAWN
RECOMMENDED DOSE:
IN AGRICULTURE
As P Source:
6.66 L COLION_P can replace 100 Kg Single super phosphate.
8 to 16 ml per liter of water for spraying/ Sprinkler/Drip; first during preparation of the
soil before sowing; Then when the crop is 1-2 weeks old; Again one week before when it is
going to flowering, Lastly 1-2 weeks before harvesting.
In the cases of diseases like downy mildew of grapes, fruit rot, Root Rot & citrus
Gummosis, Late blight of Tomato etc;
20- 30 ml per L of Water for spraying/ Sprinkler/Drip.
Other key nutrients like all water-soluble fertilizers, nitrogen and trace elements can be
mixed with COLION_P except for calcium fertilizers and concentrated magnesium
solutions.
In hydroponic systems, it should normally be added to the B tank along with the sulphates
and trace elements.
COLION_P has a buffering effect which will help stabilize the pH of the solution at around
5.5.
IN ANIMAL FEEDS:
1 L per MT Feed regularly replacing 10 Kg DCP of 18% P, and 50g PHYTASE of 10000
IU/g
Or
0.5 ml per 1 L in drinking water to replace 10 Kg DCP of 18% P, and 50g PHYTASE of
10000 IU/g in feed
36. PROXIMATE ANALYSIS:
Phosphorous as P: 0.18 % Min
Phosphorous as P2O5: 0.382 % Min
Chloride as Cl : 0.01%max
Iron(as Fe): 0.0005%max
Arsenic(as As): 0.0005%max.
pH: 4.35-4.85
Suitable pH Buffers
PACKING:
25 L
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Mitchell, C and J Adam (2004). Alabama Coop. Ext. Sys., S-04-04. May 2004.
Wells, KL, JE Dollaride and RE Mundell (2000). Comm. Soil Sci Plant Anal.
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