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‫الرحيم‬‫الرحمن‬‫هللا‬ ‫بسم‬
‫بالعباد‬ ‫لطيف‬ ‫هللا‬ ‫و‬ ‫هللا‬ ‫الى‬ ‫أمري‬ ‫وأفوض‬
‫العظيم‬‫هللا‬ ‫صدق‬
Zagazig University
Faculty of Medicine
Radiology Department
imaging for medical
students
By
Dr. Samar Shehata
lecturer of Diagnostic Radiology
•CNS imaging
(CT scanner)
Principle of CT
• Computed tomography scanning an
x-ray source and detector, situated
180o across from each other, move
360o around the patient,
continuously sending and detecting
information on the attenuation of x-
rays as they pass through the body.
Finally, a computer manipulates and
integrates the acquired data and
assigns numerical values based on
the subtle differences in x-ray
attenuation
A CT scan is essentially a computerized assembly of several x-ray
images taken from a series of different angles
Technique of CT
- Head CTs are performed at an angle parallel to the base of the skull,
Orbito-meatal line (Reid’s line).
- Slice thickness is generally between 5 and 10 mm.
- The patient is placed in a supine position on the table.
- Evaluation of tumors, infections and some stroke cases may benefit
from the use of contrast, but contrast is not used in the routine head CT.
CT Terminology
Attenuation
Hyperattenuating (hyperdense)
Hypoattenuating (hypodense)
Isoattenuating (isodense)
Attenuation is measured in Hounsfield units
Scale -1000 to +1000 H.U
-1000 is air, Fat is -100 HU.
0 is water , Fluids is 20:40 H.U
+1000 is cortical bone & calcification
Hg. 60:70 HU.
Cerebral lobes
Sulci and Gyri
• Sulcus
– Fissure in the brain tissue.
– Interhemispheric fissure –
divides the brain into left
and right hemispheres.
• Gyrus
– Elevated “hill” areas
between sulci.
Gyrus
Sulcus
Atamai
Meninges
 Outer dura mater (Latin for “tough
mother”), beneath which is the subdural
space;
 Arachnoid (Latin for “spider,” because it
resembles a cobweb), beneath which is the
subarachnoid space, which is accessed
during a spinal tap
 Pia mater (“soft mother”), which is
attached to the brain and dips down into
sulci
 A subarachnoid hemorrhage will extend down into
cerebral sulci, while a subdural hematoma will
not.
 Pia and dura are vascular while arachnoid is
avascular
Ventricular system & CSF
 Lateral ventricles – cerebral
hemispheres
 Third ventricle, aqueduct and 4th
ventricle are in midline and in
continuity with the central canal
 All are symmetrical and are lined
by ependyma
 150 ml produced daily by choroid
plexus( mostly in lateral
ventricles)
 Flows cephalad from basal
cisterns
13
Cerebral Arterial Territory
MCA
ACA
PCA
Normal Enhanced CT
17
Here’’’ Just Remember
Imaging of
INTRACRANIAL HEMORRHAGE
What items should be included?
• Site(intracerebral-subarachnoid-dubdural-
extradural)
• Distribution
• Stage
• Association (Mass effect)
20
B is for Blood
• Blood becomes
hypodense at
approximately 2 weeks.
• Blood becomes isodense
at approximately 1 week.
• Acute blood is bright white
on CT (once it clots).
Well defined hyperdense intracerebral hematoma seen
in the Rt basal ganglia>>>> Acute Rt basal ganglia
intracerebral hematomabasal
23
Subdural Hematoma
• Typically falx or sickle-
shaped.
• Crosses sutures, but does
not cross midline.
• Acute subdural is a marker
for severe head injury.
(Mortality approaches 80%)
• Chronic subdural usually
slow venous bleed and well
tolerated.
Axial CT scan of the brain,, demonstrates hyperdense subdural hematoma
with concave inner margin and mass effect >>>acute sub dural Lt. parietal
hematoma
Axial CT scan of the brain,,
demonstrates isodense
subdural hematoma in the LT
frontal region with midline shift
>>>Subacute subdural LT frontal
hematoma
Axial CT scan of the brain,,
demonstrates right fronto-parieto-
occipital subdural with layering
>>>acute on top of chronic
hematoma
Axial CT scan of the brain,,
demonstrates hyperdense epidural
hematoma with convex inner margin
and mass effect in the LT temporo-
occipital region >>>acute epidural LT
temporo-occipital hematoma
Extradural hematoma
SDH Vs EDH
27
Subarachnoid Hemorrhage
• Blood in the
cisterns/cortical
gyral surface
– Aneurysms
responsible for 75-
80% of SAH
– AVM’s responsible
for 4-5%
– Vasculitis accounts
for small proportion
(<1%)
– No cause is found in
10-15%
Axial CT scan of the brain,, demonstrates hyperdense
hematoma in the basal cisterns and both Sylvian fissures
>>>acute subarachnoid hemorrhage
Axial CT scan of the brain,, demonstrates
hyperdense hematoma in the basal
cisterns,falx and both Sylvian fissures as
well as intraventricular
extension>>>acute subarachnoid
hemorrhage
Cerebral contusion
32
Here’’’ Just Remember……
Imaging of
BRAIN INFARCTION
What items should be included?
• Site and Distribution ((cortical-subcortical-
basal ganglia-lobe-lacunar))
• Stage(Recent –old-hemorrhagic)
• Mass effect or evacudilatation
Infarction
• When a scan looks nearly normal , always
consider infarction
Sequential images of infarction
Acute infarction
Axial CT of the brain
shows hypoattenuated
area in the cortical and
subcortical Rt temporal
region …..Rt temporal
recent infarction
MCA Infarction
MCA (inferior devision)
Infarction
MCA (main stem) Infarction
Bilateral MCA infarction
PCA INFARCT
Axial CT of the brain shows hypoattenuated area in the cortical and
subcortical Lt occipital region >>> Lt occipital recent infarction
ACA INFARCT
Old infarction
Axial CT of the brain shows hypodense(CSF like) area in the cortical and subcortical
Rt Fronto-temporal region with evacudilatation>>>Cortical and subcortical Rt
fronto-temporal old infarction
BRAIN SOL
Pre-contrast Post-contrast
Convexicty or bifalcine meningioma
medulloblastoma
Metastatic
Abscess
51
What is
this
animal
?
Case 1 :32 y F presented to the ED
with a sudden acute onset headache
that radiated down her neck.
Case 2 :54 y F developed right sided
weakness , language deficits with her
eyes deviated towards the left.
Case 3 : 82 yo male with mental status
change after a fall.
Case 4: 62 yo female acute onset headache
Hemiplegic on the right and unable to
speak
56
57

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CNS Imaging for Medical Students

  • 1. ‫الرحيم‬‫الرحمن‬‫هللا‬ ‫بسم‬ ‫بالعباد‬ ‫لطيف‬ ‫هللا‬ ‫و‬ ‫هللا‬ ‫الى‬ ‫أمري‬ ‫وأفوض‬ ‫العظيم‬‫هللا‬ ‫صدق‬
  • 2. Zagazig University Faculty of Medicine Radiology Department
  • 3. imaging for medical students By Dr. Samar Shehata lecturer of Diagnostic Radiology
  • 6. Principle of CT • Computed tomography scanning an x-ray source and detector, situated 180o across from each other, move 360o around the patient, continuously sending and detecting information on the attenuation of x- rays as they pass through the body. Finally, a computer manipulates and integrates the acquired data and assigns numerical values based on the subtle differences in x-ray attenuation A CT scan is essentially a computerized assembly of several x-ray images taken from a series of different angles
  • 7. Technique of CT - Head CTs are performed at an angle parallel to the base of the skull, Orbito-meatal line (Reid’s line). - Slice thickness is generally between 5 and 10 mm. - The patient is placed in a supine position on the table. - Evaluation of tumors, infections and some stroke cases may benefit from the use of contrast, but contrast is not used in the routine head CT.
  • 8. CT Terminology Attenuation Hyperattenuating (hyperdense) Hypoattenuating (hypodense) Isoattenuating (isodense) Attenuation is measured in Hounsfield units Scale -1000 to +1000 H.U -1000 is air, Fat is -100 HU. 0 is water , Fluids is 20:40 H.U +1000 is cortical bone & calcification Hg. 60:70 HU.
  • 10. Sulci and Gyri • Sulcus – Fissure in the brain tissue. – Interhemispheric fissure – divides the brain into left and right hemispheres. • Gyrus – Elevated “hill” areas between sulci. Gyrus Sulcus Atamai
  • 11. Meninges  Outer dura mater (Latin for “tough mother”), beneath which is the subdural space;  Arachnoid (Latin for “spider,” because it resembles a cobweb), beneath which is the subarachnoid space, which is accessed during a spinal tap  Pia mater (“soft mother”), which is attached to the brain and dips down into sulci  A subarachnoid hemorrhage will extend down into cerebral sulci, while a subdural hematoma will not.  Pia and dura are vascular while arachnoid is avascular
  • 12. Ventricular system & CSF  Lateral ventricles – cerebral hemispheres  Third ventricle, aqueduct and 4th ventricle are in midline and in continuity with the central canal  All are symmetrical and are lined by ependyma  150 ml produced daily by choroid plexus( mostly in lateral ventricles)  Flows cephalad from basal cisterns
  • 15.
  • 19. What items should be included? • Site(intracerebral-subarachnoid-dubdural- extradural) • Distribution • Stage • Association (Mass effect)
  • 20. 20 B is for Blood • Blood becomes hypodense at approximately 2 weeks. • Blood becomes isodense at approximately 1 week. • Acute blood is bright white on CT (once it clots).
  • 21.
  • 22. Well defined hyperdense intracerebral hematoma seen in the Rt basal ganglia>>>> Acute Rt basal ganglia intracerebral hematomabasal
  • 23. 23 Subdural Hematoma • Typically falx or sickle- shaped. • Crosses sutures, but does not cross midline. • Acute subdural is a marker for severe head injury. (Mortality approaches 80%) • Chronic subdural usually slow venous bleed and well tolerated. Axial CT scan of the brain,, demonstrates hyperdense subdural hematoma with concave inner margin and mass effect >>>acute sub dural Lt. parietal hematoma
  • 24. Axial CT scan of the brain,, demonstrates isodense subdural hematoma in the LT frontal region with midline shift >>>Subacute subdural LT frontal hematoma Axial CT scan of the brain,, demonstrates right fronto-parieto- occipital subdural with layering >>>acute on top of chronic hematoma
  • 25. Axial CT scan of the brain,, demonstrates hyperdense epidural hematoma with convex inner margin and mass effect in the LT temporo- occipital region >>>acute epidural LT temporo-occipital hematoma Extradural hematoma
  • 27. 27 Subarachnoid Hemorrhage • Blood in the cisterns/cortical gyral surface – Aneurysms responsible for 75- 80% of SAH – AVM’s responsible for 4-5% – Vasculitis accounts for small proportion (<1%) – No cause is found in 10-15%
  • 28. Axial CT scan of the brain,, demonstrates hyperdense hematoma in the basal cisterns and both Sylvian fissures >>>acute subarachnoid hemorrhage
  • 29. Axial CT scan of the brain,, demonstrates hyperdense hematoma in the basal cisterns,falx and both Sylvian fissures as well as intraventricular extension>>>acute subarachnoid hemorrhage
  • 30.
  • 34. What items should be included? • Site and Distribution ((cortical-subcortical- basal ganglia-lobe-lacunar)) • Stage(Recent –old-hemorrhagic) • Mass effect or evacudilatation
  • 35. Infarction • When a scan looks nearly normal , always consider infarction
  • 36. Sequential images of infarction
  • 37.
  • 38. Acute infarction Axial CT of the brain shows hypoattenuated area in the cortical and subcortical Rt temporal region …..Rt temporal recent infarction
  • 39. MCA Infarction MCA (inferior devision) Infarction MCA (main stem) Infarction
  • 41. PCA INFARCT Axial CT of the brain shows hypoattenuated area in the cortical and subcortical Lt occipital region >>> Lt occipital recent infarction
  • 43. Old infarction Axial CT of the brain shows hypodense(CSF like) area in the cortical and subcortical Rt Fronto-temporal region with evacudilatation>>>Cortical and subcortical Rt fronto-temporal old infarction
  • 48.
  • 49.
  • 52. Case 1 :32 y F presented to the ED with a sudden acute onset headache that radiated down her neck.
  • 53. Case 2 :54 y F developed right sided weakness , language deficits with her eyes deviated towards the left.
  • 54. Case 3 : 82 yo male with mental status change after a fall.
  • 55. Case 4: 62 yo female acute onset headache Hemiplegic on the right and unable to speak
  • 56. 56
  • 57. 57