Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
A validation programme involves various components in pharmaceutical organisation related to process, equipment and product.
It is a regulatory requirement for pharmaceutical companies to perform Instrument Validation on all new instruments.
Instrument Validation requires detailed knowledge of the instrumentation system being validated and is therefore usually performed by the company supplying the instrument.
A validation programme involves various components in pharmaceutical organisation related to process, equipment and product.
It is a regulatory requirement for pharmaceutical companies to perform Instrument Validation on all new instruments.
Instrument Validation requires detailed knowledge of the instrumentation system being validated and is therefore usually performed by the company supplying the instrument.
Master batch record,batch production record ,Quality Audit Type and plan &Rec...KarishmaFuse
Standard Operating procedure(SOP), Preparation review ,Approval Issuance of master batch Record MBR and Batch Production Record (BPR) and Quality Audit Type, plan and Objectives.
Second Party Audit and External Third Party AuditShantanuThakre3
Second Party Audit:- Second-party audit is when a company performs an audit of a supplier to ensure that they are meeting the requirements specified in the contract.
External Third Party Audit:-
A third-party audit occurs when a company has decided that they want to create a Quality Management System (QMS) that conforms to a standard set of requirements, such as ISO 9001 and hire an independent auditing company to perform an audit to verify that the company has succeeded in meeting these standards.
Các nhà sản xuất thuốc đã sử dụng các biện pháp kiểm soát ô nhiễm như một yếu tố cốt lõi trong thực hành sản xuất thuốc.
Tài liệu này cung cấp các nguyên tắc kiểm soát ô nhiễm đáp ứng thực hành sản xuất tốt GMP.
Xem thêm các tài liệu khác trên kênh của Công ty Cổ phần Tư vấn Thiết kế GMP EU.
Qualification of tablet compression machinePritam Kolge
Qualification of Tablet Compression Machine ...
This topic comes under Quality Control and Quality Assurance....
This is useful for M.Pharm (Pharaceutical Quality Assurance) Students who studying in First year sem II....
This Presentation Contain following...
#Introduction
#Design Qualification
#Installation Qualification
#Operational Qualification
#Performance Qualification
#Case Study
#Conclusion
#References
Thanks For Help and Guidance of Dr. Mrs. N. M. Bhatia Mam
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Master batch record,batch production record ,Quality Audit Type and plan &Rec...KarishmaFuse
Standard Operating procedure(SOP), Preparation review ,Approval Issuance of master batch Record MBR and Batch Production Record (BPR) and Quality Audit Type, plan and Objectives.
Second Party Audit and External Third Party AuditShantanuThakre3
Second Party Audit:- Second-party audit is when a company performs an audit of a supplier to ensure that they are meeting the requirements specified in the contract.
External Third Party Audit:-
A third-party audit occurs when a company has decided that they want to create a Quality Management System (QMS) that conforms to a standard set of requirements, such as ISO 9001 and hire an independent auditing company to perform an audit to verify that the company has succeeded in meeting these standards.
Các nhà sản xuất thuốc đã sử dụng các biện pháp kiểm soát ô nhiễm như một yếu tố cốt lõi trong thực hành sản xuất thuốc.
Tài liệu này cung cấp các nguyên tắc kiểm soát ô nhiễm đáp ứng thực hành sản xuất tốt GMP.
Xem thêm các tài liệu khác trên kênh của Công ty Cổ phần Tư vấn Thiết kế GMP EU.
Qualification of tablet compression machinePritam Kolge
Qualification of Tablet Compression Machine ...
This topic comes under Quality Control and Quality Assurance....
This is useful for M.Pharm (Pharaceutical Quality Assurance) Students who studying in First year sem II....
This Presentation Contain following...
#Introduction
#Design Qualification
#Installation Qualification
#Operational Qualification
#Performance Qualification
#Case Study
#Conclusion
#References
Thanks For Help and Guidance of Dr. Mrs. N. M. Bhatia Mam
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
(Clover™) coa butcher's broom cnbbe170108Emily Wei
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com
(Clover™) coa of butea superba root powderEmily Wei
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
(Clover™) coa broccoli powder extract 016Emily Wei
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Clover Nutrition is a manufacturer of tea products, herbal extract, functional food. Main Product are Icariin 20%, Lutein 20%, Zeaxanthin 10%, Asataxanthin 2%.
info@clovercn.com www.clovernutrition.com 0086-29-81875649 Xi'an, China
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
The hemodynamic and autonomic determinants of elevated blood pressure in obes...
(Clover™) coa bitter melon extract
1. A Clover Nutrition Inc www.clovernutrition.com
A Clover Leads to Natural Life. info@clovercn.com
Address: No. 43, 6th
road Hi-tech, Hi-tech Zone, Xi’an, China
Certificate of Analysis
Product Name Bitter Melon Extract Latin Name Momordica Charantia Linn.
Batch No. CNBM150902 Mfg Date/Expi Date Sep 2th
. 2015/Sep 2th
. 2017
Quantity 800KGS Part Used Fruit
Non-Irradiated, Non-GMO
Items Specifications Results
Appearance Yellow Brown Powder Complies
Odor/Taste Characteristics Complies
Partical Size 98% through 80 meshes 100% through 80 meshes
Loss on Drying ≤5.0% 3.68%
Ash ≤5.0% 4.25%
Assay Charantin≥10% UV Charantin 10.12% UV
Heavy Metals ≤10 ppm Complies
As ≤1.00 ppm Complies
Pb ≤1.00 ppm Complies
Hg ≤1.00 ppm Complies
Cd ≤0.50 ppm Complies
Pesticide Residue
Acephate <0.5 PPM Complies
Methamidophos <0.5 PPM Complies
Parathion <0.5 PPM Complies
PCNB <10PPB Complies
Total of Plate Count <10000CFU/g 290CFU/g
Yeast and Mold <1000CFU/g 89CFU/g
Salmonella Negative Complies
E.coli Negative Complies
Storage/Packaging
Store in cool & dry place & Keep away from light.
Storage temperature: -10℃ to 30℃. 25kg in one type cardboard drum.
Shelf Life 24 months when properly stored
Conclusion
CNBM150902 batch is qualified to delivery according to test report of
certification of analysis.
Report Date: Sep 2th
. 2015 QC He Tao