This document provides information on the clinical management of sinusitis. It defines sinusitis as the inflammation of the paranasal sinuses and discusses its causes such as viruses, bacteria, fungi, allergens, and structural abnormalities. The document outlines the different types of sinusitis and their associated symptoms. It also discusses the diagnosis, complications, and homoeopathic and general management of sinusitis.
Your tonsils and adenoids are part of your lymphatic system. Your tonsils are in the back of your throat and your adenoids are higher up, behind your nose. They help protect you from infection by trapping germs coming in through your mouth and nose. Sometimes your tonsils and adenoids become infected themselves. Tonsillitis makes your tonsils sore and swollen. Enlarged adenoids can be sore, make it hard to breathe and cause ear problems.
The first treatment for infected tonsils and adenoids is antibiotics. If you have frequent infections or trouble breathing, you may need surgery. Surgery to remove the tonsils is tonsillectomy. Surgery to remove adenoids is adenoidectomy.
Your tonsils and adenoids are part of your lymphatic system. Your tonsils are in the back of your throat and your adenoids are higher up, behind your nose. They help protect you from infection by trapping germs coming in through your mouth and nose. Sometimes your tonsils and adenoids become infected themselves. Tonsillitis makes your tonsils sore and swollen. Enlarged adenoids can be sore, make it hard to breathe and cause ear problems.
The first treatment for infected tonsils and adenoids is antibiotics. If you have frequent infections or trouble breathing, you may need surgery. Surgery to remove the tonsils is tonsillectomy. Surgery to remove adenoids is adenoidectomy.
Laryngitis is inflammation of the larynx (or voicebox). Irritation or infection of the vocal chords causes them to swell and cause hoarseness or complete loss of voice.
Pharyngitis- Easy PPT for Nursing StudentsSwatilekha Das
Pharyngitis- Easy PPT for Nursing Students
organs of the respiratory system
Definition
Acute Pharyngitis definition
Causes
Clinical features
Diagnosis
Treatment
Nutritional therapy
Chronic Pharyngitis
types
Clinical manifestations
Medical management
Laryngitis is inflammation of the larynx (or voicebox). Irritation or infection of the vocal chords causes them to swell and cause hoarseness or complete loss of voice.
Pharyngitis- Easy PPT for Nursing StudentsSwatilekha Das
Pharyngitis- Easy PPT for Nursing Students
organs of the respiratory system
Definition
Acute Pharyngitis definition
Causes
Clinical features
Diagnosis
Treatment
Nutritional therapy
Chronic Pharyngitis
types
Clinical manifestations
Medical management
Sinuses are air-filled cavities within the skull bone. These hollow spaces in the skull are situated in cheek bones, forehead, behind the bridge of the nose and between the eyes. Another set is situated in the upper region of the nose and behind the eyes. All the sinuses have the same lining that is present in the nose.
• Individual sensitivity to a foreign substance that is usually harmless. These substances are called as allergens & antigen which is introduced in the immune system by a number of different routes.
• An allergic reaction can occur almost anywhere in the body. The symptom of reaction often occurs at the site of reaction.
Hayfever is best treated with a carefully selected constitutional remedy for a sustained result; however relief may be obtained with the use of acute homeopathic remedies as well as tissue salts, vitamins and minerals and herbal combinations which all have a part to play in strengthening the system.
Often developing from a cold or flu, acute sinusitis is the build up of mucous within the sinus linings. When the mucous fails to clear, the resulting congestion and warm, moist environment becomes the perfect site for bacteria to grow. Acting promptly with the indicated homeopathic remedies can help to prevent this from occurring.
Sinusitis results from viral or bacterial or allergic causes can be completely cured by proper homeopathy treatment. Find top homeopathy medicines for sinusitis. Visit Multicare Homeopathy.
Know more: https://www.multicarehomeopathy.com/diseases/6-best-homeopathic-medicines-for-Sinusitis-treatment
Similar to Clinical tips for the management of sinusitis (20)
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Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
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Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
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2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
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2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. Sinusitis is the inflammation or swelling of the tissue
lining the paranasal sinuses
It is also called rhinosinusitis
Definition
When sinuses become blocked and filled with fluid, organisms such as bacteria,
viruses and fungi can proliferate in them CAUSING SINUSITIS
Sinuses are a four pairs of air filled cavities within the facial
bones
They are lined with mucous membrane and trap dirt particles
and bacteria
3. Causes of Sinusitis
•Viral such as common cold, Bacterial or Fungal
•These cause swelling of the lining of the sinuses blocking the
opening
Infection
•Allergens such as Pollen, Irritants such as Chemical sprays,
smoke
•Exposure to these can inflame lining of the sinuses
Allergy
•Enlarged Adenoids, Nasal polyps, Deviated nasal septum
•These can impede the drainage of sinuses into the nasal cavity
Structural abnormalities
•Diseases such as Cystic Fibrosis
•Exposure to irritants such as cigarette smoke
Predisposing factors
4. Clinical types
Sudden onset
of runny,
blocked nose
,with facial
pain lasting
upto 2-4weeks
Symptoms of
sinusitis
lasting for 4-8
weeks
Symptoms
lasting for
more than 8
weeks
Several
attacks within
a year
Acute sinusitis Sub-acute Sinusitis Chronic sinusitis Recurrent Sinusitis
5. Symptoms of Sinusitis
Acute Sinusitis
Nasal blockage
Nasal discharge
Facial
pain/tenderness
Loss of smell
Cough
Fever
Bad
breath(halitosis)
Fatigue
Dental pain
Facial pain/ congestion/
sensation of fullness
Nasal obstruction
Fever
Discoloured nasal/post
nasal discharge
Headache
Bad breath
Fatigue
Dental pai
Chronic Sinusitis
6. Diagnosis
Physical examination-Facial Tenderness may be
present
X- ray( paranasal sinus radiography) –Normal
sinuses look black on x-ray, in sinusitis a dense
white /grey shadow indicating an air-fluid level
Mucous culture may reveal the causative
organism
Nasal endoscopy/CT Scan/MRI may also be used
Allergy tests to identify specific allergens
7. Complications
•Meningitis, Brain abscess
•Spread of infection to the
orbit can cause reduced/lost
vision, orbital cellulitis
•It may trigger asthma attacks
•Facial osteomylitis
•Cavernous sinus thrombosis
Though rare,
Chronic
sinusitis can
cause some
complications
8. Homoeopathic treatment is effective in
Acute and Chronic Sinusitis
In Acute phase, totality of symptoms must be
used as a guide to choosing the remedy,
exciting cause should also be considered
During the disease free period the a well
chosen constitutional, anti-miasmatic remedy
goes a long way in correcting the dyscrasia
Homoeopathic Management
9. Remedy Indications
ARSENICUM ALBUM Throbbing and burning pains in the sinuses< by light, noise, movement, after midnight, > by
lying quietly in a dark room with the head raised on pillows and warmth application. Nausea and
vomiting concurrent with sinusitis. Great thirst, desire for drink in frequent sips, rather than
gulps
ARSENICUM IODATUM Tubercular Diathesis, Dull, heavy headache, < occiput Eyeballs feel heavy, Foul otorrhœa,
Persistent, but unsatisfactory sneezing, Nose drips water, hot , green, acrid, reddens upper
lip, Coryza; with dyspnœa , post-nasal catarrh, Colds with hunger, Aching malar bones
ARUNDO Deep seated pain in sides of head with painful roots of hair, Coryza accompanied by marked
itching in the nostril & roof of the nose, Temporary loss of smell.
BELLADONNA Throbbing frontal headache < by jarring, touch, bending forward, or motion of the eyes and >
pressure and in semi erect posture, Pain appears suddenly , then disappears temporarily, only to
repeat the process of coming and going ,ailments from least exposure to cold.
ECHINAECIA Foul smelling discharges, membranous formations protruding, nose feels stopped up
ELAPS CORALLINES In chronic cases, with chronic nasal catarrah with fetid odour & greenish crusts, Pain at the root
of nose , Nose blocked, < cold drinks, wet weather, eating fruits
Homoeopathic therapeutics
for SINUSITIS
1
10. Remedy Indications
EUCALYPTUS Rheumatic-Hydrogenoid constitution, Stuffed-up sensation, thin, watery coryza, nose does not
stop running, tightness across nose bridge, Chronic catarrhal, purulent and fetid discharge,
Ethmoid and frontal sinus involved. Dull congestive headache
FAVUS Pain in Frontal and Maxillary sinuses, Dry with dry crust, Discharge of greenish pus < Morning, >
in morning after sneezing
FORMICA RUFA Marked deterrent on the formation of Nasal Polyp, Blocked sensation of NASAL POLYP
HEDERA HELIX Pain of the Ethmoidal and Frontal sinus. Inflammation of the frontal sinuses with headache.
Nasal discharge < Hot room
HEPAR SULPH Rarely indicated at the beginning of a sinusitis. Nasal discharge is thick and yellow. Nostrils
become very sore from the acrid discharge, and the nasal passages become sensitive to cold air
HIPPOZAENIUM Discharge acrid, corroding, bloody, offensive. Papules and ulceration in frontal sinus and
pharynx
HYDRASTIS Chronic sinusitis where there is thick, tenacious yellow secretion from posterior nares to throat.
Dull, pressive frontal pain, especially associated with constipation. Also useful in acute cases.
Sinusitis after suppressed coryza
Homoeopathic therapeutics
for SINUSITIS
2
11. Remedy Indications
INFLUENZINUM Polysinusitis with history of Influenza
IODUM Pain at the root of the nose, with nasal blockage
KALI BICHROMICUM Syphilitic or Scrofulous background. More adapted to sub-acute rather than acute violent
stages, Pressure and pain at root of nose, and sticking pain in nose. Septum ulcerated, round
ulcer. Fetid smell. Discharge thick, ropy, and greenish-yellow. Tough, elastic plugs from nose,
leave a raw surface, Inflammation extends to frontal sinuses, with distress and fullness at root
of nose, Dropping from posterior nares, Loss of smell. Hawking, Inability to breathe through
nose, Dryness, Coryza, with obstruction of nose, Violent sneezing. Profuse, watery nasal
discharge, Chronic inflammation of frontal sinus with stopped-up sensation , Fontal pain usually
over one eye
KALI IODATUM Syphilitic background, incipient organic changes. Tip of nose red; profuse, acrid, hot, watery,
thin discharge. Ozæna, with perforated septum. Sneezing. Nasal catarrh, involving frontal sinus.
Stuffiness and dryness of nose, without discharge. Profuse, greenish, irritating discharges.
Intense pain over eyes and root of nose
LACHESIS Severe frontal headache after cessation of nasal discharge. Pain > after flow begins. Bloody
discharge
Homoeopathic therapeutics
for SINUSITIS
3
12. Remedy Indications
LUFFA OPERCULATA Acute or chronic inflammation . Dryness of the nasal mucous membrane with adhering crust
formation,< confined air, > Fresh air of the outside
MENTHOLUM Frontal headache, pain over frontal sinus, descends to eyeballs. Supra orbital pain over left eye.
Pain in face above zygoma with numbness. Pain in eyeballs. Coryza with post-nasal dripping.
Cold sensation in nose. Eustachian tubes feel blocked and some deafness. Short, dry cough,
worse smoking. Asthmatic breathing, with congestive headache
MERCURIUS SOLUBILIS Thick, greenish, offensive, acrid nasal discharge. Sensitive to both heat and cold. Profuse
perspiration without relief. Tongue is flabby with imprint of teeth, profuse salivation, and foul
breath.
NAT MUR Suitable for early stages with symptoms like sneezing, loss of smell and a blocked sensation
with watery discharge. Throbbing frontal headache
NUX VOMICA Treats symptoms of sinusitis where sneezing and runny nose are frequent by day, but nose
stopped at night, and it is not uncommon for a patient to wake up with complaints around 3-4
a.m,<in warm room, > in cold air
PENTHORUM Constant wet feeling in nose with no amount of blowing will relieve. Discharge thick, pus-like,
streaked with blood. Post nasal cattarh of puberty
PENICILLINUM Right Frontal Sinusitis. Right sided frontal headache. Discharge is yellow, thick, < Humid cold
weather, > Warmth
Homoeopathic therapeutics
for SINUSITIS
4
13. Remedy Indications
PNEUMOCOCCINUM Pain on Left Frontal Sinuses, Sub-orbital frontal pain < Humid weather, > Open air
PULSATILLA Headache <in a warm room and better in open air, cold application & pressure. Pain rapidly
shifting from one part to another. The nasal discharge is thick, bland & yellowish-green. Marked
thirstlessness.
PYROGEN Pansinusitis with fever, headache, Mostly the sphenoidal sinus is involved
SABADILLA Spasmodic sneezing, with running nose. Coryza, with severe frontal pains and redness of eyes
and lachrymation. Copious, watery, nasal discharge. Sensitive smell. Pain in alternate sides of
forehead. Unilateral head pains. Tongue feels burning sensation
SILLICEA Indicated for chronic sinusitis, chronic congestion accompanied by headache that tends to be
worse in the right eye. Pain is < by cold, movement, light, noise, and mental concentration (such
as when studying), uncovering the head but > by wrapping warmly and pressure
SPIGELIA Forepart of nose always dry, discharge through posterior nares chronic catarrh, with post-nasal
dropping of bland mucus. Fetor oris. Left supra-orbital or occipital pain; boring
STICTA PULMONALIA Feeling of fullness at the root of nose. Dryness of nasal membrane, constant need to blow the
nose, but no discharge. Dry scabs, especially in evening & night. Dull headache, with dull heavy
pressure in forehead & root of nose before discharges appear
Homoeopathic therapeutics
for SINUSITIS
5
14. Eucalyptus Q
Ocimum sanctum Q
Hydrastis Q
Mother tinctures used for inhalation
Steam inhalation using water medicated with
15-20 drops, 2-3 times daily.
15. Steam inhalation with water medicated with mother
tinctures like Hydrastis, ocimum sanc & Eucayptus
Use a humidifier in the room
Drinking lots of fluids helps to keep the mucus thin,
preventing their blockage
Jal and Sutra Neti , the yogic technique of flushing out
the nasal passages & sinuses using salt water and thread
may help
Use a nasal saline solution. While they don't contain
medicine, they can help keep your nasal passages moist
Flush out the sinuses. Nasal irrigation with salt water
can clear out mucus (and other debris) and keep sinuses
moist
Putting a warm, wet towel on the face may help relieve
some of the pressure
General Measures
16. Dr Ashok Sharma, CMO
Dr Jithesh T.K, C.M.O
Dr Prasad Mahajan, CMO
Dr Pradip Kumar Roy, S.M.O
Dr Ram Kumar, SMO
Dr Malay Kumar Ray, M.O
Dr Cheshta Nagrath, M.O
Dr Deepti Chawla
C.M.O, Dte. of AYUSH
Contributors: Compiled & Edited by: