Claw hand, or intrinsic minus hand, is caused by paralysis of the intrinsic hand muscles due to ulnar nerve injury. This results in hyperextension of the MP joints and flexion of the PIP and DIP joints, impairing hand function. Management involves restoring flexion at the MP joints and extension at the PIP joints through static procedures like capsulotomy or dynamic tendon transfers. Dynamic transfers use expendable donor tendons like the ECRL/ECRB to restore finger flexion and grip strength. Legendary orthopedic surgeon Dr. Paul Brand pioneered many tendon transfer techniques for treating leprosy-related hand deformities and rehabilitating patients.
Hand rehabilitation following flexor tendon injuriesAbey P Rajan
hand rehabilitation following flexor tendon injuries include introduction, clinical anatomy, tendon nutrition, tendon healing, post op. management, special cases, summary
Hand rehabilitation following flexor tendon injuriesAbey P Rajan
hand rehabilitation following flexor tendon injuries include introduction, clinical anatomy, tendon nutrition, tendon healing, post op. management, special cases, summary
Hand anatomy and biomechanics wrist examination.pptxIbnSaad1
Humans are distinct from other primates by the
miraculous structure of the hand.
With its 27 degrees of freedom and its opposing thumb, the
hand is a highly developed and complex grasping organ
This enables a wide range of movement combinations while
simultaneously allowing adaptation of force, speed, and
facileness.
Moreover, the hand also features a highly specific sensory
and tactile organ that human beings use to perceive and
assess themselves and their surroundings. Owing to its
capacity for making gestures, the hand plays an important
role in interpersonal communication
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
8. Normal Hand Functions
To be purposeful, motion
must be controlled, and
joints stabilized by
antagonists
9. Normal Hand Function
In a normal hand, the transition from one stable
position to another is rhythmic
Groups of muscles act in proper phase and
cooperate with one another- synergistic motion
10. Normal Hand Function
When a major muscle in the hand is paralyzed the
balance of the hand is disrupted.
11.
12. Claw Hand-Intrinsic Minus Hand
Loss of Intrinsic function –Lumbricals and interossei
Hyperextension o f M C P joints
Flexion o f PIP and D I P joints
Loss of hand dexterity and strength
Complete vs incomplete claw
14. Biomechanics of finger movements
Prime extensor of MCP is long
finger extensor
Prime extensor of IP joint is
Lumbricals and Interossi
Interossei much stronger than
lumbricals
Prime flexor of MCP is
Lumbricals and Interossi
Prime flexor of IPJ is long
finger flexors
Hook making
15.
16. Clawhand-Pathoanatomy
Without stabilization o f M C P J in slight flexion,
long extensor function “blocked” b y diversion
of this tension to s a g i t t a l band, producing
hyperextension and blocking extensor's ability t o
extend PIPJ
17.
18. LOSS O F GRASP
Paralysis of a d d u c t o r pollicis muscle
Impairment of p r e c i s i o n grip
Loss of normal cascade of finger extension and
flexion
19. Aetiology
Leprosy in endemic areas
Trauma to Ulnar nerve
Compression in cubital tunnel
Compression in Guyons canal
Neuropathologies
Syringomyelia
CMT
Poliomyelitis
MND
20. Clinical Signs
Bouvier's maneuver -to test
the integrity of the central slip
and the lateral bands of the
extensor expansion
23. Management
Active and passive finger ROM
Patient compliance
Grip strength
Then demonstrate Bouvier's maneuver
Consider operations that address MPJ hyperextension
Capsulodesis or tenodesis of the MP joint
24. Management
If Bouviers not demonstrable
A static procedure not useful
A tendon transfer is needed to provide flexion at MPJ
and extension at the PIPJ
25. Static Techniques
They prevent hyperextension of the MPJ by either shortening
their palmar capsules or tenodeses
Static procedures avoid the need for tendon transfers
Do not restore the normal pattern of finger flexion and strength
Correction may stretch
out over time
32. Dynamic Tendon Transfers
Transferring functional muscle-tendon units to restore another by
transferring the working unit to a new location.
Sacrificing an expendable muscle-tendon unit (eg wrist extensor
donor,) so that hand
function remains balanced.
If grip strength is to be improved
If the MCP joints need to be
flexed beyond 40, then significant stretching of
the PIP extensor mechanism has ensued and
dynamic tendon transfers to the lateral bands is
indicated to improve the clawing.
Condition of soft tissue gliding planes
33. Advantages of Dynamic Transfers
Correction of the claw deformity
Improving grip strength,
Restoration of power pinch
Restoring the synchronistic flexion of the fingers.
34. Routes of transfer
1.The volar route
Brand (1961) using a wrist extensor and
Bunnell (1942) using a FDS
35. Routes of transfer
2.The dorsal route
Brand (1958)
Transfer though the intermetacarpal spaces
Volar to the deep transverse metacarpal ligaments
Through the lumbrical canals
46. A tribute to Paul Brand
Legendary Orthopaedic surgeon
Helped humankind to better understand and treat leprosy
First physician to appreciate that leprosy did not cause the
rotting away of tissues, but it was the loss of the sensation
of pain which made sufferers susceptible to injury
Innovated numerous tendon transfers
47. Born 1914 to British parents in Vellore
Education & medical training 1923-46 in Britain
First professor of Orthopaedics & Hand research at CMC Vellore in
1946-1965
Performed thousands of corrective surgeries on leprotic deformities
He was awarded the Hunterian professorship of the Royal College of
Surgeons in 1952
Queen Elizabeth honoured him with a title of the Commander of the
Order of the British Empire in 1961
48. A tribute to Paul Brand
Rreceived the U.S. Surgeon General's Medal for his
rehabilitation work in Carville, Louisiana.
His thesis, "Clinical Mechanics of the Hand," is still
regarded as an authoritative reference for hand &
reconstructive surgeons
Author of 100 scientific papers and six books
Authored three inspirational books
Fearfully and Wonderfully Made,
In His Image
Pain - The Gift Nobody Wants.
Died 2003
49. God designed the human body so that it is able to
survive because of pain-Paul Brand
Editor's Notes
To be purposeful, motion must be controlled, and joints crossed by moving tendons must be stabilized by balanced antagonistic muscles.
An outstanding example of this stabilization is maintenance of wrist extension by its extensors, which prevent the wrist from being flexed by the strong finger flexors when a fist is made.
Beginning with the wrist flexed and the fingers extended and abducted, the wrist can be extended and the fingers can be flexed, and then the original position can be resumed with ease.
In treating muscle imbalance, the first choice for transfer should be tendons whose muscles are normally synergistic with the weakened or paralyzed ones.
When a major muscle in the hand is paralyzed, in addition to loss of power to perform any particular function for which the muscle is directly responsible, the balance of the hand is disrupted.
Paralysis of the intrinsic metacarpophalangeal joint flexors and intrinsic interphalangeal joint extensors (interossei and lumbricals) leads to unopposed metacarpophalangeal joint extension and interphalangeal joint flexion by the extrinsic digital extensors and flexors. The interphalangeal joints remain flexed even though a strong extensor force is exerted at the metacarpophalangeal joints; without stabilization of the metacarpophalangeal joints in a neutral or slightly flexed position by the intrinsics, the long extensors cannot extend the interphalangeal joints.