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Chronic
Glomerulonephritis
Benisha Julian
Poststreptococcal GN,
1%
Membranous GN,
30%
IgA nephropathy,
30%
Idiopathic,
20%
Membranoproliferative
GN
50%
Focal
Segmental
Glomerulosclerosis
80%-50%
Rapidly
Progressive
GN
90%
Causes
Normal sized
kidney
Contracted,
granular
kidney
Gross Features
Small size
Contracted, diffuse granular kidneys
Cortical Atrophy
Microscopic Features
• Glomerulus: hyalinized
• Tubules: Atrophied &
contains hyalinized
casts.
• Interstitium: Fibrosed
with lymphocytic
infiltration
• Vessels: Arterial or
aterioral sclerosis
1
2
4
3
2. Proteinuria
3. Edema
4.Azotemia and Uraemia
Clinical Features
Uraemic frost
1. Hypertension
Other symptoms of renal degeneration
• Anemia
• Weight loss
• Drowsiness
• Fatigue
• Muscle cramps
• Nausea, vomitting
Prognosis
Acute
GN
Chronic
GN
Chronic
Kidney
Failure
Treatment
Kidney
Transplant
Dialysis
Thank you!

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Chronic Glomerulonephritis