CHILDHOOD
OBESITY
DEFINITION
• BMI is the most widely used parameter to
define obesity.
• In children >2yrs,obesity is defined as BMI >/=
95th percentile.
• BMI between 85th-95th percentile falls in the
overweight range.
• Weight for height >120% is considered
obesity.
• It is a global public health problem sparing
only dramatically poor regions with chronic
food scarcity.
• Prevalence is 31% in age group of 2-6yrs,
16% in ages 6-19yrs.
PREVALENCE
ETIOLOGY
1.Environmental factors :
Increased consumption of high carbohydrate
beverages,fast food,
increased snacking between meals,
decline in levels of physical activity,
increase in sedentary activities,
high pressure for academic performance,
socioeconomic status,race,gender,
maternal education level,
parental obesity,
prenatal factors like weight gain during
pregnancy,high birth weight,gestational
diabetes,IUGR with early infant catch up growth,
chronic partial sleep loss
(1.>> hunger and appetite due to decreased
leptin levels and increased ghrelin levels,
2.decreased glucose tolerance and insulin
sensitivity due to alterations in glucocorticoids
levels,
3.synthesis of orexins,peptides in lateral
hypothalamus increasing feeding)
2.Genetic causes :
3.Endocrine causes :
• Monitoring of stored fats,control over
appetite,satiety occurs through
neuroendocrine feedback loops
• Linking adipose tissue,CNS and GI tract.
FROM THE GIT
Stimulating appetite Promoting satiety
Ghrelin Cholecystokinin
Glucagon like peptide-1
Peptide YY
FROM THE ADIPOCYTES
Adiponectin (>> levels in fasting,<< in obesity)
Leptin(= satiety,
low levels stimulate food intake,high levels inhibit
hunger)
FROM THE BRAIN
Neuropeptide Y
Agouti related peptide stimulate appetite
Orexin
Melanocortins
Alpha melanocortin stimulating hormone satiety
Endocrine causes
• Cushing syndrome (central
obesity,hirsutism,moon face,hypertension)
• Growth hormone deficiency (short
stature,slow linear growth)
• Hyperinsulinism (nesidioblastosis,pancreatic
adenoma,Mauriac syndrome)
• Hypothyroidism (short stature,weight
gain,constipation,cold intolerance)
• Pseudohypoparathyroidism (short
metacarpals,subcutaneous
calcifications,dysmorphic facies,MR,short
stature,hypocalcemia,hyperphosphatemia)
4.CONSTITUTIONAL OBESITY
• No organic cause.
• Due to imbalance between energy intake and
expenditure.
• These children are tall for age ->
differentiating factor from pathological
obesity.
• Normal development,obesity is proportional.
• Unnecessary investigations to be avoided.
5.HYPOTHALAMIC OBESITY
• Following
surgery,radiation,tumors,trauma,infection.
• Rapid onset obesity sets in.
6.DRUGS
• Anti epileptic drugs,steroids,estrogen,atypical
antipsychotics.
COMORBIDITIES
1.Type-2 diabetes (>> insulin resistance)
2.Hypertension
3.Hyperlipidemia
4.Non alcoholic fatty liver disease,cirrhosis
5.Risk of chronic inflammation (low levels of
adiponectin - anti-inflammatory peptide,
high levels of proinflammatory peptides IL-
6,TNF-a )
6.Obstructive sleep apnea
7.Orthopedic complications like Blount
disease,slipped femoral capital epiphysis
8.Mental health problems like low self
esteem,depression,eating disorders
9.Metabolic syndrome
10.PCOS
EVALUATION
• Identified as a part of routine medical checkup.
• Perform detailed physical examination.
• Charting growth charts for weight,height,BMI.
• Consider possible medical causes for obesity
(poor linear growth,rapid changes in weight gain).
• Detailed history of family eating and activity
patterns
(description of regular meal,snacking,physical
and sedentary activities).
• Family history of adiposity and obesity related
disorders.
• Laboratory testing to identify comorbid
conditions.
INTERVENTION
• Nutritional advice + exercise + cognitive
behavioral therapy.
• Meals should be based on
fruits,vegetables,whole grains,lean meat,fish
and poultry.
• Gradual approach to cut down calories.
• Family support is crucial.
RECOMMENDED CALORIC INTAKE
DESIGNATED BY AGE AND GENDER
“TRAFFIC LIGHT” DIET PLAN
• Groups foods into those which can be
consumed without any limitation (green),
in moderation (yellow), reserved for
infrequent treats (red).
• Can be adapted to any ethnic group/regional
cuisine.
• Increasing physical activity contributes to
weight loss,decreases risk for cardiovascular
disease.
• Restriction of screen time to no more than
2hrs/day in children >2yrs old,no television for
children less than 2yrs (AAP).
• Pharmacological therapy :
Adjunctive,>> rate of weight loss
• Bariatric surgery :
For adolescents with a BMI >/= 40,
after attaining complete skeletal maturity,
suffering from medical problems associated with
obesity,
after they have failed 6 months of multidisciplinary
weight management program
(Roux-en-Y,adjustable gastric band)
PREVENTION
• Improved food choices+increased physical
activity+reduced screen time.
• Promotion of breast feeding(exclusive for 6
months,total BF for 12months).
• Introduction of infant foods at 6 months with
focus on cereals,fruits,vegetables.
• Introduction of lean meat,poultry,fish later in first
year of life.
• Avoiding highly sugared beverages and foods.
• Family approach , scheduled meals.
• Frequent snacking to be avoided.
• Limiting screen time for children.
• 60min/day of activity for children.
• Encourage walking to school.
• Use of mass media.
THANK YOU

Childhood obesity

  • 1.
  • 2.
    DEFINITION • BMI isthe most widely used parameter to define obesity. • In children >2yrs,obesity is defined as BMI >/= 95th percentile. • BMI between 85th-95th percentile falls in the overweight range. • Weight for height >120% is considered obesity.
  • 3.
    • It isa global public health problem sparing only dramatically poor regions with chronic food scarcity. • Prevalence is 31% in age group of 2-6yrs, 16% in ages 6-19yrs. PREVALENCE
  • 4.
    ETIOLOGY 1.Environmental factors : Increasedconsumption of high carbohydrate beverages,fast food, increased snacking between meals, decline in levels of physical activity, increase in sedentary activities,
  • 5.
    high pressure foracademic performance, socioeconomic status,race,gender, maternal education level, parental obesity, prenatal factors like weight gain during pregnancy,high birth weight,gestational diabetes,IUGR with early infant catch up growth,
  • 6.
    chronic partial sleeploss (1.>> hunger and appetite due to decreased leptin levels and increased ghrelin levels, 2.decreased glucose tolerance and insulin sensitivity due to alterations in glucocorticoids levels, 3.synthesis of orexins,peptides in lateral hypothalamus increasing feeding)
  • 7.
  • 9.
    3.Endocrine causes : •Monitoring of stored fats,control over appetite,satiety occurs through neuroendocrine feedback loops • Linking adipose tissue,CNS and GI tract.
  • 10.
    FROM THE GIT Stimulatingappetite Promoting satiety Ghrelin Cholecystokinin Glucagon like peptide-1 Peptide YY FROM THE ADIPOCYTES Adiponectin (>> levels in fasting,<< in obesity) Leptin(= satiety, low levels stimulate food intake,high levels inhibit hunger)
  • 11.
    FROM THE BRAIN NeuropeptideY Agouti related peptide stimulate appetite Orexin Melanocortins Alpha melanocortin stimulating hormone satiety
  • 13.
    Endocrine causes • Cushingsyndrome (central obesity,hirsutism,moon face,hypertension) • Growth hormone deficiency (short stature,slow linear growth) • Hyperinsulinism (nesidioblastosis,pancreatic adenoma,Mauriac syndrome)
  • 14.
    • Hypothyroidism (shortstature,weight gain,constipation,cold intolerance) • Pseudohypoparathyroidism (short metacarpals,subcutaneous calcifications,dysmorphic facies,MR,short stature,hypocalcemia,hyperphosphatemia)
  • 15.
    4.CONSTITUTIONAL OBESITY • Noorganic cause. • Due to imbalance between energy intake and expenditure. • These children are tall for age -> differentiating factor from pathological obesity. • Normal development,obesity is proportional. • Unnecessary investigations to be avoided.
  • 16.
    5.HYPOTHALAMIC OBESITY • Following surgery,radiation,tumors,trauma,infection. •Rapid onset obesity sets in. 6.DRUGS • Anti epileptic drugs,steroids,estrogen,atypical antipsychotics.
  • 17.
    COMORBIDITIES 1.Type-2 diabetes (>>insulin resistance) 2.Hypertension 3.Hyperlipidemia 4.Non alcoholic fatty liver disease,cirrhosis 5.Risk of chronic inflammation (low levels of adiponectin - anti-inflammatory peptide, high levels of proinflammatory peptides IL- 6,TNF-a )
  • 18.
    6.Obstructive sleep apnea 7.Orthopediccomplications like Blount disease,slipped femoral capital epiphysis 8.Mental health problems like low self esteem,depression,eating disorders 9.Metabolic syndrome 10.PCOS
  • 19.
    EVALUATION • Identified asa part of routine medical checkup. • Perform detailed physical examination. • Charting growth charts for weight,height,BMI. • Consider possible medical causes for obesity (poor linear growth,rapid changes in weight gain). • Detailed history of family eating and activity patterns (description of regular meal,snacking,physical and sedentary activities).
  • 20.
    • Family historyof adiposity and obesity related disorders. • Laboratory testing to identify comorbid conditions.
  • 25.
    INTERVENTION • Nutritional advice+ exercise + cognitive behavioral therapy. • Meals should be based on fruits,vegetables,whole grains,lean meat,fish and poultry. • Gradual approach to cut down calories. • Family support is crucial.
  • 26.
  • 27.
    “TRAFFIC LIGHT” DIETPLAN • Groups foods into those which can be consumed without any limitation (green), in moderation (yellow), reserved for infrequent treats (red). • Can be adapted to any ethnic group/regional cuisine.
  • 29.
    • Increasing physicalactivity contributes to weight loss,decreases risk for cardiovascular disease. • Restriction of screen time to no more than 2hrs/day in children >2yrs old,no television for children less than 2yrs (AAP).
  • 30.
    • Pharmacological therapy: Adjunctive,>> rate of weight loss
  • 32.
    • Bariatric surgery: For adolescents with a BMI >/= 40, after attaining complete skeletal maturity, suffering from medical problems associated with obesity, after they have failed 6 months of multidisciplinary weight management program (Roux-en-Y,adjustable gastric band)
  • 33.
    PREVENTION • Improved foodchoices+increased physical activity+reduced screen time. • Promotion of breast feeding(exclusive for 6 months,total BF for 12months). • Introduction of infant foods at 6 months with focus on cereals,fruits,vegetables. • Introduction of lean meat,poultry,fish later in first year of life. • Avoiding highly sugared beverages and foods.
  • 34.
    • Family approach, scheduled meals. • Frequent snacking to be avoided. • Limiting screen time for children. • 60min/day of activity for children. • Encourage walking to school. • Use of mass media.
  • 35.

Editor's Notes

  • #5 Due to advent of computers
  • #11 Promote fat storage
  • #17 octreotide
  • #18 Gall stones
  • #20 Gh deficiency,hypothyroidism,cushings…..duration severity of obesity…
  • #26 Dietary changes of other fanily members too