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1 © Gabriel Chua, 2013
Chapter 5: Cell Division
Important terms and concept
1. Haploid – Cell with single __________________ set of chromosome (n)
2. Diploid – Cell with _____ sets of chromosomes (2n)
3. Cell division:
a) Mitosis – 1 parent cell (2n)  ___ daughter cells ( _____ )
b) Meiosis – 1 parent cell (2n)  ___ daughter cells ( _____ )
4.
5.1) Mitosis
1. 1 parent cell (2n)  _____ daughter cells ( _____ )
2. It is part of the cell cycle (Interphase  Mitosis  Cytokinesis)
3. Interphase is divided into:
a) ____ __________  Growth of cell by producing proteins and organelles
b) ____ __________  Synthesis of DNA (thread-like chromatin)
c) ____ __________  Growth of cell by producing proteins and organelles
4. Mitosis is divided into __________________, _________________, _______________
and __________________
2 © Gabriel Chua, 2013
Prophase  Chromosomes start to appear and _______________ as 2
identical chromatids
 Nuclear membrane ______________________ and
nucleolus ___________________
 Centrioles move apart to ______________ sides
 ____________ ______________ begins to form
Metaphase  Chromosomes move to cell’s _________________
 Chromosomes ___________ ________ at cell’s equator
with centromeres attached to spindle fibre
 Each ______________faces its own pole
Anaphase  Chromosomes divide into two
 Each ___________ _______________ separate and
move to opposite poles
 When the chromatids reached its own pole, they become
independent chromosomes
Telophase  There are now ____sets of chromosomes, one at each
pole
 Chromosomes become __________________ structures
 Spindle fibre __________________
 ___________ ________________ begins to form
around both sets of chromosomes
 __________________ reappears
 _________________ begins
5. Cytokinesis in animal cells is by forming _________________ while that of plant cells is
by forming __________________
6. Importance of mitosis
a) Repair _______________ cells and ______________ dead cells
b) ________________ reproduction in unicellular organisms
c) Preserve ________________ number of chromosome
d) Ensure new cells are __________________ to parent cells
3 © Gabriel Chua, 2013
7. Application of mitosis
a) Repair damaged cells and replace dead cells
b) Tissue culture
c) Clonnnig
d) Uncontrolled mitosis causes cancer
5.2) Meiosis
1. 1 parent cell (2n)  _____ daughter cells ( ____ )
2. Meiosis is divided into:
a) Meiosis I b) Meiosis II
 ______________________  __________________________
 ______________________  __________________________
 ______________________  __________________________
 ______________________  __________________________
Prophase I  Chromosomes _____________ and ____________
 Each chromosome consists of 2 ____________
_____________
 _________________ _________________ pair together
(bivalent) via _________________
 The criss-cross between homologous chromosomes is
known as ___________________
 This results in genetic variation
 _______________ move to opposite poles
 ____________ ____________ forms
 _____________ ______________ and ______________
disintegrate
Metaphase I  Paired homologous chromosomes line up at cell’s
________________
 Each chromosome are attached to spindle fibre at
centromeres
 Each ____________ faces its own pole
Anaphase I  Paired homologous chromosomes _______________
from each other and move to _______________ pole
4 © Gabriel Chua, 2013
Telophase I  Chromosomes reached its own pole
 Each pole has ____________ chromosome set
 Spindle fibre ______________
 ___________ __________ and ____________ reform
 Cytokinesis begins
3. Meiosis II is the same as mitosis
4. Importance of meiosis
a) Allow trait inheritance in offspring
b) Maintain _____________ number of chromosomes in each generation
c) Ensure production of ____________ gametes in ____________ reproduction
d) Produce genetic _________________
Comparison between Meiosis I and Meiosis II
Meiosis I Meiosis II
Similarities
1. Consists of ____ stages, ie. ___________, ____________, ___________ & ___________
2. Involves division of nucleus and cytoplasm
Differences
Synapsis
Crossing over
In metaphase I, ___________
________________________
line up at equator
Metaphase
In metaphase II, __________
_______________ line up at
equator
In anaphase I, ____________
________________________
separate and move to opposite
side
Anaphase I
In anaphase II, ___________
_______________ separate
and move to opposite side
_____ daughter cells ( ____ )
Number of daughter cells
______ daughter cells ( ___ )
5 © Gabriel Chua, 2013
Comparison between Meiosis and Mitosis
Meiosis Mitosis
Similarities
1. Both process are cell division process
2. Chromosomes only replicate once
Differences
Place occur
Number of division
_____ daughter cells ( ___ ) Number of daughter cells ____ daughter cells ( ___ )
Synapsis
Number of cytokinesis
Crossing over
Each daughter cell has _____
the number of chromosome
of parent cell
Number of chromosomes in
daughter cells
Each daughter cell has the
________ number of
chromosome as parent cell
Genetic composition are
________________________
to parent cell or to each other
Genetic composition of
daughter cells
Genetic composition are
_________________ to
parent cell and each other
Occurs during interphase
before Meiosis I begins DNA replication
Occurs during interphase
before mitosis begins



Role in animal body



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Chapter 5

  • 1. 1 © Gabriel Chua, 2013 Chapter 5: Cell Division Important terms and concept 1. Haploid – Cell with single __________________ set of chromosome (n) 2. Diploid – Cell with _____ sets of chromosomes (2n) 3. Cell division: a) Mitosis – 1 parent cell (2n)  ___ daughter cells ( _____ ) b) Meiosis – 1 parent cell (2n)  ___ daughter cells ( _____ ) 4. 5.1) Mitosis 1. 1 parent cell (2n)  _____ daughter cells ( _____ ) 2. It is part of the cell cycle (Interphase  Mitosis  Cytokinesis) 3. Interphase is divided into: a) ____ __________  Growth of cell by producing proteins and organelles b) ____ __________  Synthesis of DNA (thread-like chromatin) c) ____ __________  Growth of cell by producing proteins and organelles 4. Mitosis is divided into __________________, _________________, _______________ and __________________
  • 2. 2 © Gabriel Chua, 2013 Prophase  Chromosomes start to appear and _______________ as 2 identical chromatids  Nuclear membrane ______________________ and nucleolus ___________________  Centrioles move apart to ______________ sides  ____________ ______________ begins to form Metaphase  Chromosomes move to cell’s _________________  Chromosomes ___________ ________ at cell’s equator with centromeres attached to spindle fibre  Each ______________faces its own pole Anaphase  Chromosomes divide into two  Each ___________ _______________ separate and move to opposite poles  When the chromatids reached its own pole, they become independent chromosomes Telophase  There are now ____sets of chromosomes, one at each pole  Chromosomes become __________________ structures  Spindle fibre __________________  ___________ ________________ begins to form around both sets of chromosomes  __________________ reappears  _________________ begins 5. Cytokinesis in animal cells is by forming _________________ while that of plant cells is by forming __________________ 6. Importance of mitosis a) Repair _______________ cells and ______________ dead cells b) ________________ reproduction in unicellular organisms c) Preserve ________________ number of chromosome d) Ensure new cells are __________________ to parent cells
  • 3. 3 © Gabriel Chua, 2013 7. Application of mitosis a) Repair damaged cells and replace dead cells b) Tissue culture c) Clonnnig d) Uncontrolled mitosis causes cancer 5.2) Meiosis 1. 1 parent cell (2n)  _____ daughter cells ( ____ ) 2. Meiosis is divided into: a) Meiosis I b) Meiosis II  ______________________  __________________________  ______________________  __________________________  ______________________  __________________________  ______________________  __________________________ Prophase I  Chromosomes _____________ and ____________  Each chromosome consists of 2 ____________ _____________  _________________ _________________ pair together (bivalent) via _________________  The criss-cross between homologous chromosomes is known as ___________________  This results in genetic variation  _______________ move to opposite poles  ____________ ____________ forms  _____________ ______________ and ______________ disintegrate Metaphase I  Paired homologous chromosomes line up at cell’s ________________  Each chromosome are attached to spindle fibre at centromeres  Each ____________ faces its own pole Anaphase I  Paired homologous chromosomes _______________ from each other and move to _______________ pole
  • 4. 4 © Gabriel Chua, 2013 Telophase I  Chromosomes reached its own pole  Each pole has ____________ chromosome set  Spindle fibre ______________  ___________ __________ and ____________ reform  Cytokinesis begins 3. Meiosis II is the same as mitosis 4. Importance of meiosis a) Allow trait inheritance in offspring b) Maintain _____________ number of chromosomes in each generation c) Ensure production of ____________ gametes in ____________ reproduction d) Produce genetic _________________ Comparison between Meiosis I and Meiosis II Meiosis I Meiosis II Similarities 1. Consists of ____ stages, ie. ___________, ____________, ___________ & ___________ 2. Involves division of nucleus and cytoplasm Differences Synapsis Crossing over In metaphase I, ___________ ________________________ line up at equator Metaphase In metaphase II, __________ _______________ line up at equator In anaphase I, ____________ ________________________ separate and move to opposite side Anaphase I In anaphase II, ___________ _______________ separate and move to opposite side _____ daughter cells ( ____ ) Number of daughter cells ______ daughter cells ( ___ )
  • 5. 5 © Gabriel Chua, 2013 Comparison between Meiosis and Mitosis Meiosis Mitosis Similarities 1. Both process are cell division process 2. Chromosomes only replicate once Differences Place occur Number of division _____ daughter cells ( ___ ) Number of daughter cells ____ daughter cells ( ___ ) Synapsis Number of cytokinesis Crossing over Each daughter cell has _____ the number of chromosome of parent cell Number of chromosomes in daughter cells Each daughter cell has the ________ number of chromosome as parent cell Genetic composition are ________________________ to parent cell or to each other Genetic composition of daughter cells Genetic composition are _________________ to parent cell and each other Occurs during interphase before Meiosis I begins DNA replication Occurs during interphase before mitosis begins    Role in animal body  